Adrianna Masters, M.D. , Ph.D.

Program Director & Assistant Professor

Program Director & Assistant Professor

 


Education/Training

Institution and LocationDegreeDateField of Study
Wake Forest Baptist Medical Center2015-2019Radiation Oncology Residency Program
University of Louisville School of Medicine2014-2015Internal Medicine Preliminary Year
University of Louisville School of MedicinePh.D.2013

Doctor of Philosophy, Biochemistry and Molecular Biology

Molecular Bases of Inherited Bone Marrow Failures: Shwachman-
Diamond Syndrome and Diamond Blackfan Anemia

University of Louisville School of MedicineM.D.2006-2014Physician Scientist Training Program
Wake Forest UniversityB.S.2001-2005Chemistry

Positions and Honors

Academic AppointmentsDate
Program Director & Assistant Professor, Department of Radiation Oncology, University of Louisville, Louisville, KY8/2022 - Present
Assistant Professor, Southern Illinois School of Medicine, Springfield, IL8/2019 - 4/2022
Radiation Oncology associate physician, Springfield Clinic, Springfield, IL7/2020 - 4/2022

Radiation Oncology physician, partner track, University Radiologists, SC Springfield, IL

8/2019 - 7/2020

Other Experience and Professional Memberships

ADMINISTRATIVE & LEADERSHIP ACTIVITIES:

  • Founding Member and Senior Executive Committee for SWRO (2017 - Present)
  • Membership Committee, ACRO; Diversity and Inclusion Subcommittee Chair; Women’s Subcommittee (2017 - Present)

  • New Practitioners Committee, ACRO (2017 - Present) 

  • New Practitioners Committee, ACRO Chair (2022 - Present)

  • Board of Chancellors, ACRO (2022 - Present)

  • Department representative, Cancer Control Committee, Memorial Medical Center (2020 - 2022)

  • Research Committee, Springfield Clinic (2020 - 2022)

  • IT Committee, Springfield Clinic (2020 - 2022)

  • Breast Cancer Leadership Team, Springfield Clinic (2020 - 2022) 

  • WFU, Clinical Operations Committee, Department of Radiation Oncology (2017 - 2019)

  • American Medical Women’s Association, Louisville: Treasurer (2007 - 2008)

  • Pathology Course Reform Committee, University of Louisville SOM (2008)

PROFESSIONAL MEMBERSHIPS:
  • 2017 – Present         American Society of Clinical Oncology (ASCO)
  • 2017 – Present         American College of Radiation Oncology (ACRO)
  • 2017 – 2019             Association of Residents in Radiation Oncology (ARRO)
  • 2019 - Present         American Association for Women in Radiology (AAWR)
  • 2017 – 2019            Radiological Society of North America (RSNA)
  • 2017 – Present        Society for Women in Radiation Oncology (SWRO)
  • 2016 – Present        Radiation Research Society (RRS)
  • 2016 – Present        American College of Radiology (ACR)
  • 2015 – Present        American Society of Therapeutic Radiology and Oncology (ASTRO)
  • 2014 – 2019            American Brachytherapy Society (ABS)
  • 2008 – Present       American Physician Scientists Association (APSA)
  • 2005 – Present       American Medical Women’s Association (AMWA)

Honors and Awards
  • Recognized as top 10% of providers within specialty for overall patient satisfaction scores, Press-Ganey, Springfield Clinic, 2022

  • MD/PhD Physician-Scientist Training Program University of Louisville, One of two fully funded students. University of Louisville School of Medicine, 2006-2014

  • Physician/Scientist Award: Biochemistry and Molecular Biology, University of Louisville School of Medicine, 2014
  • Dr. Norvin Green Memorial Prize (Best Thesis), University of Louisville, 2014
  • Medical Student Travel Grant: American Brachytherapy Society Meeting, University of Louisville, 2014
  • George F. Hankins, Zachary T. Smith, William K. Stamey, and Robert C. Byrd Scholarships, Wake Forest University, 2001-2005

Selected peer-reviewed publications

1. Dover L, Hentz C, Khan J, Lee A, Masters A, Doke K, Goodman C. Implications of Medical Board Certification Practices on Family Planning and Professional Trajectory for Early Career Female Radiation Oncologists. Pract Radiat Once. 2022 Mar-Apr; 12(2):95-102.

2. Su J, Song Q, Qasem S, O’Neill S, Lee J, Furdui CM, Pasche B, Metheny-Barlow L, Masters AH, Lo HW, Xing F, Watabe K, Miller LD, Tatter SB, Laxton AW, Whitlow CT, Chan MD, Soike MH, Ruiz J. Multi-Omic Analysis of Brain Metastasis Outcomes Following Craniotomy. Front Oncol. 2021Apr 6; 10:615472.

3. Lecompte MC, Hughes RT, Farris M, Masters A, Soike MH, Lanier C, Glenn C, Cramer CK, Watabe K, Su J, Ruiz J, Whitlow CT, Wang G, Laxton AW, Tatter SB, Chan MD. Impact of Brain metastasis velocity on neurologic death for brain metastasis patients experiencing distant brain failure are initial stereotactic radio surgery. J Neurooncol. 2020 Jan; 146(2):285-292.

4. Helis CA, Hughes RT Glenn CW, Lanier CM, Masters AH, Dohm A, Ahmed T, Ruiz J, Triozzi P, Gondal H, Cramer CK, Tatter SB, Laxton AW, Xing F, Lo HW, Watabe K, Wang G, Whitlow CT, Chan MD. Predictors of Adverse Radiation Effect in Brain Metastasis Patients Treated with Stereotactic Radiosurgery and Immune Checkpoint Inhibitor Therapy. Int J Radiat Oncol Viol Phys. 202 Sep 1; 108(1):295-303.

5. McTyre E, Ayala-Peacock D, Soike M, Hepel J, Page B, Shen C, Kleinberg L, Contessa J, Corso C, Chiang V, Henson A, Cramer C, Ruiz J, Pasche B, Watabe K, D’Agostino R, Su J, Laxton A, Tatter S, Fiveash J, Ahluwalia M, Kotecha R, Chao S, Braunstein S, Attia A, Chung C, Chan M. Multi-Institutional Validation of Brain Metastasis Velocity, a Recently Defined Predictor of Outcomes Following Stereotactic Radiosurgery. Radiother Oncol. 2020 Jan;142:168-174. doi: 10.1016/j.radonc.2019.08.011.

6. Masters AH, Hughes R, Strowd L, Lamar Z, Winkfield KM. Efficacy of Very-low Dose Radiotherapy for Refractory Mycosis Fungoides of the Face. JAAD Case Rep. 2019 Apr 5;5(4):348-351. doi: 10.1016/j.jdcr.2019.01.027

7. Albert A, Knoll M, Doke K, Masters AH, Lee A, Dover L, Hentz C, Puckett L, Goodman C, Osborn V, Barry P, Jagsi R. #WomenWhoCurie: Leveraging Social Media to Promote Women in Radiation Oncology. Adv Radiat Oncol. 2019 Jan 29;4(2):218-225. doi: 10.1016. j.adro.2019.01.003

8. Hughes RT, Masters AH, McTyre ER, Farris MK, Chung C, Page BR, Kleinberg LR, Hepel J, Contessa JN, Chiang V, Ruiz J, Watabe K, Su J, Fiveash JB, Braunstein S, Chao S, Attia A, Ayala-Peacock DN, Chan MD. Initial SRS for Patients with 5 to 15 brain Metastases. Int J Radiat Oncol Biol Phys. 2019 Aug 1;104(5):1091-1098. doi: 10.1016/j.ijrobp.2019.03.052.

9. Hughes R, Soike M, Prajapati S, Lin A, Ververs J, Masters AH, Helis C, Blackstock A, Farris M. Stereotactic body radiotherapy for an isolated splenic metastasis from ovarian carcinoma. J Radiosurg SBRT 2019;6 (2): 161-163

10. Lanier C, Hughes R, Ahmed T, Lecompte M, Masters A, Petty W, Ruiz J, Triozzi P, Su J, O’Neil S, Watabe K, Cramer CK, Laxton A, Tatter S, Wang G, Whitlow C, Chan MD. Immunotherapy is associated with improved survival and decreased neurologic death after SRS for brain metastases from lung and melanoma primaries. Neurooncol Pract. 2019 Sep; 6(5);402-409.

11. Farris MK, Wheless WH, Hughes RT, Soike MH, Masters AH, Helis CA, Chan MD, Cramer CK, Ruiz J, Lycan T, Petty WJ, Ahmed T, Leyrer CM, Blackstock AW. Limited-Stage Small Cell Lung Cancer: Is Prophylactic Cranial Irradiation Necessary? Practical Radiat Oncol. 2019 Nov;9(6):e599-e607

12. Osborn VW, Doke K, Griffith KA, Jones R, Lee A, Maquilan G, Masters AH, Albert AA, Dover LL, Puckett LL, Hentz C, Kahn JM, Colbert LE, Barry PN, Jagsi R. A Survey Study of Female Radiation Oncology Residents' Experiences to Inform Change. Int J Radiat Oncol Biol Phys. 2019 Aug 1;104(5):999-1008. doi: 10.1016/j.ijrobp.2019.05.013. Epub 2019 May 17.

13. LeCompte M, McTyre E, Strowd R, Lanier C, Soike M, Hughes R, Masters A, Cramer C, Farris M, Ruiz J, Watabe K, Laxton A, Tatter S, Winkfield K, Chan M. Impact of Diabetes Mellitus on Outcomes in Patients with Brain Metastasis Treated with Stereotactic Radiosurgery. J Radiosurg SBRT. 2018;5(4):285-291.

14. McTyre E, Ayala-Peacock D, Contessa J, Corso C, Chiang V, Chung C, Fiveash J, Ahluwalia M, Kotecha R, Chao S, Attia A, Henson A, Hepel J, Braunstein S, Chan M. Multi-Institutional Competing Risk Analysis of Distant Brain Failure and Salvage Patterns after Upfront Radiosurgery without Whole Brain Radiotherapy for Brain Metastases. Ann Oncol. 2018 Feb 1; 29(2):497-503. doi: 10.1093/annonc/mdx740.

15. Osborn V, Lee A, Maquilan G, Dover L, Masters A, Puckett L, Albert A, Hentz C, Doke K, Barry P. Society for Women in Radiation Oncology: Residents’ perspectives on #MeToo and the founding of SWRO. Applied Radiation Oncology. March 2018.

16. LeCompte MC, McTyre E, Henson A, Farris M, Okoukoni C, Cramer CK, Triozzi P, Ruiz J, Watabe K, Lo HW, Munley MT, Laxton AW, Tatter SB, Zhou X, Chan M. Survival and Failure Outcomes Predicted by Brain Metastasis Volumetric Kinetics in Melanoma Patients Following Upfront Treatment with Stereotactic Radiosurgery Alone. Cureus. 2017 Dec 11; 9(12):e1934. doi: 10.7759/cureus.1934

17. Dohm A, McTyre ER, Okoukoni C, Henson A, Cramer CK, LeCompte MC, Ruiz J, Munley MT, Qasem S, Lo HW, Xing F, Watabe K, Laxton AW, Tatter SB, Chan MD. Staged Stereotactic Radiosurgery for Large Brain Metastases: Local Control and Clinical Outcomes of a One-Two Punch Technique. Neurosurgery. 2017 Jul 7 doi: 10.1093/neuros/nyx355.

18. Barry PN, Henson AL, Goodwin N, Cash E, Mezera M, Wilson L, Redman R, Perez C, Bumpous J, Potts K, Silverman C, Dunlap N. Factors predicting suitability of organ preservation with radiation therapy in laryngeal and hypopharyngeal cancer. J of Solid Tumors. 2014 Dec 4; 4(4):9-17. doi: 10.5430/jst.v4n4p9

19. Farrar JE, Quarello P, Fisher R, O'Brien KA, Aspesi A, Parrella S, Henson AL, Seidel NE, Atsidaftos E, Prakash S, Bari S, Garelli E, Arceci RJ, Dianzani I, Ramenghi U, Vlachos A, Lipton JM, Bodine DM, Ellis SR. Exploiting pre-rRNA processing in Diamond Blackfan anemia gene discovery and diagnosis. Am J Hematol. 2014 Oct;89(10):985-91.

20. Singh SA, Goldberg TA, Henson AL, Husain-Krautter S, Nihrane A, Blanc L, Ellis SR, Lipton JM, Liu JM. p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5. PLoS One. 2014 Feb 18;9(2)

21. Henson A, Moore J, Alard P, Wattenberg M, Liu J, Ellis S. Mitochondrial function is impaired in yeast and human cellular models of Shwachman Diamond syndrome, Biochem. Biophys. Res. Commun. 2013 Jul 19;437(1):29-34.

22. Henson A, Sezgin G, Singh S, Nihrane A, Singh S, Wattenberg M, Alard P, Ellis S, Liu J. Impaired Growth, Hematopoietic Colony Formation, and Ribosome Maturation in Human Cells Depleted of Shwachman-Diamond Syndrome Protein SBDS. Pediatr Blood Cancer. 2012 Sep 19. Feb;60(2):281-6

23. Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, Ellis S, Schambach A, Baum C, Richter J, Larsson J, Bryder D, Karlsson S. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond- Blackfan anemia. Blood. 2011 Dec 1;118(23):6087-96.

24. Henson AL, Ellis SR. Finding a diamond in the (mouse is) rough. Blood. 2010 Oct 14; 116(15): 2623-5.

25. Donninger H, Allen N, Henson A, Pogue J, Williams A, Gordon L, Kassler S, Dunwell T, Latif F, Clark GJ. Salvador protein is a tumor suppressor effector of RASSF1A with hippo pathway-independent functions. J Biol Chem. 2011 May 27;286(21): 18483-91.

26. Thomas LR, Henson A, Reed JC, Salsbury FR, Thorburn A. Direct binding of Fas- associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD. J Biol Chem. 2004 Jul 30;279(31):32780-5.