Child and Adolescent Health Research Design and Support Unit

Child and Adolescent Health Research Design and Support Unit



Child and Adolescent Health Research Design and Support (CAHRDS) Unit of the Department of Pediatrics of the University of Louisville School of Medicine exists to improve effectiveness, quality, safety and delivery of health care and promote optimal health for all children in Kentucky. The Unit will support missions of the University of Louisville, School of Medicine, and the Department of Pediatrics through the application of pediatric health services research. We define health services research as follows:

Health services research is a multidisciplinary field of study that aims to understand factors that influence child and adolescent health, which include individuals, families, communities, and organizations. Areas of study may include health behaviors, social determinants of health, access to care, care quality, health care costs, resource utilization, and system structures, processes, and policies.


The faculty and staff of the CAHRDS Unit are guided by values of 1) improving child health and well-being through developing evidence that identifies best practices, 2) pursuing scientific rigor with integrity and accountability, and 3) building collaborative and inclusive University and community partnerships.


With the mindset of "what is best for children," the CAHRDS Unit expects to produce excellent research that serves the health and well-being of children, their families and communities, and our colleagues who provide health care services to them.

Programs and Studies

Kentucky Antibiotic Awareness Program

Louisville Twin Study

To Request Assistance

Please submit an email to:   and include the following:

  • Name
  • division 
  • general description of the project
  • what services you think you will need and 
  • deadline (if applicable).

We look forward to working with you.

Louisville Twin Study

The Louisville Twin Study was internationally recognized as one of the oldest, largest, and most comprehensive studies of child development related to multiple birth status and is unique because of the extensive, longitudinal assessments and because of the relatively low rate of mobility out of the Louisville area. This low rate of immobility is important because it increases the likelihood that the participants or some of their family members may still be in the Louisville area and, thus, may be available for future studies. The Louisville Twin Study data consists of extensive longitudinal evaluations of child factors such as temperament, personality, cognitive abilities, physical growth, health status, accidental injuries, and school achievement from birth through adolescence. Genetic data were collected on a sub-sample of the twins and their families.

Until recently, the Louisville Twin Study was closed and the data were in storage. Efforts are currently underway to ensure that the Louisville Twin Study data are preserved and converted to newer data formats. The Louisville Twin Study was an important part of the history of the University of Louisville and the Department of Pediatrics. Participants contributed significantly to our understanding of the complex interactions between genes and the environment. Twin and family studies provide a unique method to examine the many factors that contribute to developmental and health outcomes of children and to understand the underlying processes responsible for individual differences in those outcomes. We appreciate the willingness of the former participants to take part in such an important project. We also appreciate the creativity, dedication, and hard work of the former researchers and staff members who worked diligently over many years to develop and execute the studies that make up the Louisville Twin Study.

In addition to archiving the previously collected data, efforts began in mid-2008 to locate previous participant.  Former participant who are now adults will be recruited into a new study of adult health. A variety of methods will be used to locate former participants. If you formerly participated in the Louisville Twin Study, we would love to hear from you. If you know someone who may have participated, we would appreciate you sharing this information with him or her. While we are not currently enrolling new twins, we may develop new research projects in the future involving twins who did not previously participate.

Kentucky Antibiotic Awareness

Did you know that Kentucky has one of the highest rates of antibiotic prescribing in the country?

Kentucky Antibiotic Awareness (KAA) is a campaign to reduce inappropriate antibiotic use across the state of Kentucky.  KAA encourages healthcare professionals and community members to utilize the educational resources provided here.  The materials available on this site were developed by health professional researchers from the University of Louisville, Department of Pediatrics, Child and Adolescent Health Research Design and Support Unit (CAHRDS).

All Kentucky Antibiotic Awareness materials on the website may be reproduced as needed; however, literature content should not be altered without permission.

Stay Up-to-Date:


Kentucky Outpatient Antimicrobial Stewardship Implementation Workbook

This comprehensive workbook  was created to assist providers in implementing stewardship initiatives in their practice.

Kentucky Antibiotic Awareness Commitment Posters

Order customized Commitment Posters to display in your waiting area and exam rooms. Free while supplies last.



This project was supported by the following: Kentucky Cabinet for Health and Family Services:Department for Medicaid Services under the State University Partnership contract titled “Improving Care Quality for Children Receiving Kentucky Medicaid”, Norton Children’s Hospital, and the University of Louisville School of Medicine, Department of Pediatrics; School of Public Health and Information Sciences.

This content is solely the responsibility of the authors and does not necessarily represent the official views of the Cabinet for Health and Family Services, Department for Medicaid Services