Recent Student Publications

Publications produced from University of Louisville work

Current MD/PhD Students and Recent Graduates

Tracy EP, Nair R, Roe G, Beare JE, Beyer A, LeBlanc AJ. Adipose Stromal Vascular Fraction Reverses Mitochondrial Dysfunction and Hyperfission in Aging-Induced Coronary Microvascular Disease. Am J Physiol Heart Circ Physiol. 2022 Aug 26. doi:10.1152/ajpheart.00311.2022.

Tracy EP, Dukes M, Beare J, Rowe G, Nair R, LeBlanc AJ. Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease. Antioxid Redox Signal. 2022 Aug 11. doi: 10.1089/ars.2021.0249. Online ahead of print.

Tracy EP, Rowe G, LeBlanc AJ. Cell therapy-induced recovery of dysfunctional microvasculature. Aging (Albany NY). 2022 Jul 13; 14(13):5296-5298. doi: 10.18632/aging.204183. Epub 2022 Jul 13.

Sokhadze G, Campbell PW, Charalambakis N, Govindaiah G, Guido W, McGee AW. Cre driver mouse lines for thalamocortical circuit mapping. J Comp Neurol. 2022 May; 530(7): 1049-1063. doi: 10.1002/cne.25248. Epub 2021 Oct 20.

Engelbrecht E, Metzler MA, Sandell LL. Retinoid signaling regulates angiogenesis and blood-retinal barrier integrity in neonatal mouse retina. Microcirculation. 2022 Apr; 29(3):e12752. doi 10.1111/micc.12752. Epub 2022 Mar 5.

Tracy EP, Stielberg V, Rowe G, Benson D, Nunes SS, Hoying JB, Murfee WL, LeBlanc AJ. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration. Am J Physiol Heart Circ Physiol. 2022 Apr 1: 322(4): H647-H680. doi 10.1152/ajpheart.00674.2021. Epub 2022 Feb 18.

Knipe RS, Spinney JJ, Abe EA, Probst CK, Franklin A, Logue A, Giacona F, Drummond M, Griffith J, Brazee PL, Hariri LP, Montesi SB, Black KE, Hla T, Kuo A, Cartier A, Engelbrecht E, Christoffersen C, Shea BS, Tager AM, Medoff BD. Am J Respir Cell Mol Biol. 2022 Jan:66(1):38-52. doi: 10.1165/rcmb.2020-0408OC.

Rowe G, Tracy E, Beare JE, LeBlanc AJ. Cell Therapy rescues aging-induced beta-1 adrenergic receptor and GRK2 dysfunction in the coronary microcirculation. Geroscience. 2022 Feb; 44(1):329-348. doi: 10.1007/s11357-021-00455-6. Epub 2021 Oct 4.

Woolley CR, Brinkman NC, Cash ED, Chandran SK, Mitchell TC. An Unexpected Role for Cell Density Rather than IgM in Cell-Surface Display of the Fc Receptor for IgM in Cell-Surface Display of the Fc Receptor for IgM on Human Lymphocytes. Immunohorizons. 2022 Jan 18: 6(1):47-63. doi: 10.4049/immunohorizons.2100094.

Slomnicki LP, Wei G, Burke DA, Hodges ER, Myers SA, Yarberry CD, Morehouse JR, Whittemore SR, Saraswat Ohri S, Hetman M. Limited Changes in locomotor recovery and unaffected white matter sparing after spinal cord contusion at different times of day. PLoS One. 2021 Nov 23; 16(11):e0249981. doi:10.137/journal.pone.0249981. eCollection 2021.

Noe JT, Rendon BE, Geller AE, Conroy LR, Morrissey SM, Young LEA, Buntz RC, Kim EJ, Wise-Mitchell A, Barbosa deSouza Rizzo M, Relich ER, Baby BV, Johnson LA,Affronti HC, McMaster KM,Clem BF, Gentry MS, Yan J, Wellen KE, Sun RC, Mitcehll RA. Lactate supports a metabolic-epigenetic link in macrophage polarization. Sci Adv. 2021 Nov 12; 7(46):eabi8602. doi 10.1126/sciadv.abi8602. Epub 2021 Nov 12

Morrissey SM, Zhang F, Ding C, Montoya-Durango DE, Hu X, Yang C, Wang Z, Yuan F, Fox M, Zhang HG, Guo H, Tieri D, Kong M, Watson CT, Mitchell RA, Zhang X, McMasters KM, Huang J, Yan J. Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic nich through glycolytic dominant metabolic reprogramming. Cell Matab. 2021 Oct 5; 33(10):2040-2058.e10. doi: 10.1016/j.cmet.2021.09.002. Epub 2021 Sep 23.

Tracy EP, Hushes W, Beare JE, Rowe G, Beyer A, LeBlanc AJ. Aging-Induced Impairment of Vascular Function: Mitochondrial Redox Contributions and Physiological/Clinical Implications. Antioxid Redox Signal. 2021 Oct 20; 35(12):974-1015. doi:10.1089/ars.2021.0031. Epub 2021 Sep 17.

Donninger H, Harrell-Stewart D, Clark GJ. Detection of Endogenous RASSF1A Interacting Proteins. Methods Mol Biol. 2021; 2262:303-310. doi: 10.1007/978-1-0716-1190-6_18.

Morrissey SM, Geller AE, Hu X, Tieri D, Ding C, Klaes CK, Cooke EA, Woeste MR, Martin ZC, Chen  O, Bush SE, Zhang HG, Cavallazzi R, Clifford SP, Chen J, Ghare S, Barve SS, Cai L, Kong M, Rouchka EC, McLeish KR, Uriarte SM, Watson CT, Huang J, Yan J. A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients. JCI Insight. 2021 May 10;6(9):e 148435. doi: 10.1172/jci.insight.148435 

Wei GZ, Saraswat OS, Khattar NK, Listerman AW, Doyle CH, Andres KR, Karuppagounder SS, Ratan RR, Whittemore SR, Hetman M. Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery. PLoS One. 2021 Apr 5;16(4):e0249591. doi: 10.1371/journal.pone.0249591. Collection 2021.

Cash E, Sephton S, Woolley C, Elbehi AM, RIA, Ekine-Afolabi B, Kok VC. The role of circadian clock in cancer hallmark acquisition and immune-based cancer therapeutics. J Exp Clin Cancer Res. 2021 Apr 1;40(1):119. doi: 10.1186/s13046-021-01919-5.

Woeste MR, Geller AE, Martin RCG 2nd, Polk HC Jr. Optimizing the Combination of Immunotherapy and Trans-Arterial Locoregional Therapy for Stages B and C Hepatocellular Cancer. Ann Surg Oncol. 2021 Mar;28(3):1499-1510. doi: 10.1245/s10434-020-09414-5. Epub 2021 Jan 3.

Noe JT, Mitchell RA. MIF-Dependent Control of Tumor Immunity. Front Immunol. 2020 Nov 25;11:609948. doi: 10.3389/fimmu.2020.609948. eCollection 2020.

Govindaiah G, Campbell PW, Guido W. Differential Distribution of Ca2+ Channel Subtypes at Retinofugal Synapses. eNeuro. 2020 Nov 5; 7(6):ENEURO.0293-20.2020 doi:10.1523/ENEURO.0293-20.2020 Print 2020 Nov/Dec.

Tracy EP, Gettler BC, Zakhari JS, Schwartz RJ , Williams SK, Birla RK. 3D Bioprinting the Cardiac Purkinje System Using Human Adipogenic Mesenchymal Stem Cell Derived Purkinje Cells. Cardiovasc Eng Technol. 2020 Oct;11(5):587-604. doi: 10.1007/s13239-020-00478-8. Epub 2020 Jul 24.

Bridgwater C, Geller A, Hu X, Burlison JA, Zhang HG, Yan J, Guo H. 89Zr-Labeled Anti-PD-L1 Antibody Fragment for Evaluating In Vivo PD-L1 Levels in Melanoma Mouse Model. Cancer Biother Radiopharm. 2020 Oct;35(8):549-557. doi: 10.1089/cbr.2019.3056. Epub 2020 Apr 21.

Campbell PW, Govindaiah G, Masterson SP, Bickford ME, Guido W. Synaptic properties of the feedback connections from the thalamic reticular nucleus to the dorsal lateral geniculate nucleus. J Neurophysiol. 2020 Aug 1: 124(2):404-417. doi: 10.1152/jn.00757.2019. Epub 2020 Jul 1.

Geller A., Yan J. Could the Induction of Trained Immunity by Beta-Glucan Serve as a Defense Against COVID-19? Front Immunol. 2020 Jul 14;11:1782. doi: 10.3389/fimmu.2020.01782. eCollection 2020

Morrissey SM, Yan J. Exosomal PD-L1: Roles in Tumor Progression and Immunotherapy. Trends Cancer. 2020 Jul;6(7):550-558.                                                doi: 10.1016/j.trecan.2020.03.002 Epub 2020 Mar 29.

Tracy E, Rowe G, LeBlanc AJ. "Cardiac tissue remodeling in health aging: the road to pathology." Am J Physiol Cell Physiol. 2020 Jul 1;319(1):C166-C182. doi: 10.1152/ajpcell.00021.2020. Epub 2020 May 20.

Woeste MR, Bhutiani N, Geller AE, Eldridge-Hindy H, McMasters KM, Ajkay N. "Identifying Factors Predicting Prolonged Opioid Use After Mastectomy." Ann Surg Oncol. 2020 Apr;27(4):993-1001. doi: 10.1245/s10434-019-08171-4. Epub 2020 Jan 21.

Harrell Stewart DR, Clark Gj. Pumping the brakes on RAS - negative regulators and death effectors of RAS. J Cell Sci. 2020 Feb 10; 133(3)jcs238865. doi: 10.1242/jcs.238865.

Chen X, Morrissey S, Chen F, Yan J. "Novel Insight into the Molecular and Metabolic Mechanisms Orchestrating IL-17 Production in yS T Cells." Front Immunol. 2019 Dec 3;10:2828. doi: 10.3389/fimmu.2019.02828 eCollection 2019.

SenGupta S, Rane MJ, Uriarte SM, Woolley C, Mitchell TC. "Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation." Innate Immun. 2019 Nov;25(8)473-486. doi: 10.1177/1753425919871994. Epub 2019 Sep 3.

Noe JT, Mitchell RA. "Tricarboxylic acid cycle metabolites in the control of macrophage activation and effector phenotypes." J Leukoc Biol. 2019 Aug;106(2):359-367. doi: 10.1002/JLB.3RU1218-496R. Epub 2019 Feb 15.

Geller A, Shrestha R, Yan J. "Yeast-Derived Betta-Glucan in Cancer: Novel Uses of a Traditional Therapeutic." Int J Mol Sci. 2019 Jul 24;20(15):3618. doi: 10.3390/ijms20153618.

Rowe G, Kelm NQ, Beare JE, Tracy E, Yuan F, LeBlanc AJ. "Enhanced beta-1 adrenergic receptor responsiveness in coronary arterioles following intravenous stromal vascular fraction therapy in aged rats." Aging (Albany NY). 2019 Jul 11;11(13):4561-4578. doi: 10.18632/aging.102069.

Geller, A, Yan J. "The Role of Membrane Bound Complement Regulatory Proteins in Tumor Development and Cancer Immunotherapy." Front Immunol. 2019 May 21:10:1074. doi: 10.3389/fimmu.2019.01074. eCollection 2019

Charalambakis NE, Govindaiah G, Campbell PW, Guido W. Developmental Remodeling of Thalamic Interneurons Requires Retinal Signaling. J Neurosci. 2019 May 15; 39(20):3856-3866. doi: 10.1523/JNEUOSCI.2224-18.2019. Epub 2019 Mar 6.

Harrell Stewart D, Hobbing K, Schmidt ML, DonningerH, Clark GJ. The role of RASSF proteins in modulating RAS driven lung tumors in vivo. J. Thorac Dis. 2019 May; 11(Suppl 9):S1436-S1437. doi: 10.21037/jtd.2019.03.60.

Sokhadze G, Campbell PW, Guido W. Postnatal development of cholinergic input to the thalamic reticular nucleus of the mouse. Eur J Neurosci. 2019 Apr; 49(8):978-989. doi:10.1111/ejn.13942. Epub 2018 Jul 21.

Dwenger M, Kowalski WJ, Ye F, Yuan F, Tinney JP, Setozaki S, Nakane T, Masumoto H, Campbell P. Guido W, Keller BB. Chronic optical pacing conditioning of H-iPSC engineered cardiac tissues. J Tissue Eng. 2019 Apr 17; 10:2041731419841748. doi: 10.1177.2041731419841748. ecollection 2019 Jan-Dec.

Fleming C, Morrissey SM, Cai Y, Yan J. "yS T Cells: Unexpected Regulators of Cancer Development and Progression." Trends Cancer. 2017 Aug;3(8):561-570. doi:10.1016/j.trecan.2017.06.003. Epub 2017 Jul 17.

Fleming, C, Cai Y, Sun X, Jala VR, Xue F, Morrissey S, Wei YL, Chien YH, Zhang HG, Haribabu B, Huang J, Yan, J. "Microbiota-activated CD 103+ DCs stemming from microbiota adaptation specifically drive yST17 proliferation and activation." Microbiome. 2017 Apr 24;5(1):46. doi: 10.1186/s40168-017-0263-9