Clinical Trials


Spine Mets Studies

BCC-RAD-11-01Randomized Phase II Trial of Stereotactic Radiation Therapy (SRT) versus SRT plus Vertebral Augmentation Procedure (VAP) for Vertebral Metastasis
RTOG 0631

PHASE II/III STUDY OF IMAGE-GUIDED RADIOSURGERY/SBRT FOR LOCALIZED SPINE METASTASIS

Head and Neck Studies

RTOG 1216

Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin versus Docetaxel versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck

RTOG 1016Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer
RTOG 0920Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer
RTOG 1008A Randomized Phase II Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors
RTOG 0912

A Randomized Phase II Study of Concurrent Intensity Modulated Radiation Therapy (IMRT), Paclitaxel and Pazopanib (NSC 737754)/Placebo, for The Treatment of Anaplastic Thyroid Cancer

Plant ExosomesPreliminary Clinical Trial Investigating the Ability of Plant Exosomes to Abrogate Oral Mucositis Induced by Combined Chemotherapy and Radiation in Head and Neck Cancer Patients
RASH Study

Preemptive therapy of Cetuximab (Erbitux®) induced skin rash using doxycycline, sunscreen, hydrocortisone, and moisturizer in colorectal and head and neck cancer patients

Lung Studies
Trental/Vitamin EThe effect of pentoxifylline and Vitamin E in preventing radiation-induced toxicity in the treatment of recurrent or new primary non-small cell lung cancers using stereotactic ablative radiotherapy (SABR) in patients previously treated with thoracic radiation
RTOG 0538

CALGB 30610/Endorsed Study: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide

RTOG 0839Randomized Phase II Study of Pre-Operative Chemoradiotherapy +/- Panitumumab (IND #110152) Followed By Consolidation Chemotherapy In Potentially Operable Locally Advanced (Stage IIIA, N2+) Non-Small Cell Lung Cancer
RTOG 0937

Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC)

RTOG 1106

RTOG 1106/ACRIN 6697, Randomized Phase II Trial of Individualized Adaptive Radiotherapy Using During-Treatment FDG-PET/CT and Modern Technology in Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

RTOG 1306A RANDOMIZED PHASE II STUDY OF INDIVIDUALIZED COMBINED MODALITY THERAPY FOR STAGE III NON-SMALL CELL LUNG CANCER (NSCLC)
BCC-RAD-11-02A Feasibility Study Using Four-Dimensional CT Imaging to Evaluate Lung Strain in Patients Treated with External Beam Radiation Therapy for Primary Lung Cancer
Breast Studies
BCC-AHFRT-10A Phase II Study of Accelerated Hypofractionated Radiotherapy (AHFRT) after Breast Conserving Surgery (BCS) in Medically Underserved Patients
NSABP-51/RTOG 1304A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
Brain Tumor Studies
RTOG 1205Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma