Division of Environmental Medicine

Welcome to University of Louisville's Division of Environmental Medicine, a division within the UofL Department of Medicine.

Envirome Institute Building 2021Mission

The Division of Environmental Medicine was created in 2018 within the Department of Medicine with the mission to understand the relationships between the environment and human health towards preventing and mitigating chronic disease through environmental adaptations and interventions. The division supports a multidisciplinary research program focused on studying how environmental conditions and characteristics relate to the development, mitigation, or prevention of cardiovascular and metabolic disease (e.g. heart disease, diabetes). Faculty within the division conduct place-based clinical and basic research, educate the next generation of environmental health and medicine scientists, and engage with Louisville communities.


Environmental Medicine

Environmental medicine is a multidisciplinary field involving environmental science, medicine, chemistry, toxicology, epidemiology, sociology, and other disciplines. It is a specialized form of environmental health, a branch of public health, which advances health and well-being by identifying and limiting exposure to hazardous agents in the environment. Environmental medicine scientists study how these environmental exposures are related to the causes and effects of disease and test interventions that can prevent and mitigate disease formation and progression.   


Research Foci

Natural Environment

  • Effects of green environments on cardiovascular and metabolic diseases
  • Relationships between components of nature, such as pollen and biodiversity, on human health  
  • How fundamental systems of the ecosphere (air, water, and soil) contribute to human health, wellbeing, or disease

Social Environment

  • Effects of ambient and roadway air pollution (PM2.5) on cardiovascular and metabolic disease progression
  • Effects of volatile organic compounds (VOCs) on the cardiovascular and metabolic disease progression
  • Developing methods to spatially visualize pollution and disease risk and burdens among communities

Personal Environment

  • Effects of tobacco and vaping on cardiovascular and metabolic disease progression
  • Relationships between lifestyle patterns (sleep, diet, exercise) and cardiovascular and metabolic disease progression
  • Developing novel approaches to measure environmental factors that impact human health, wellbeing, or disease


The Envirome

The Human Envirome is the complete set of natural, social, and personal conditions that shape each person's health. Unique to every person, over the course of their lifetime, their envirome regulates and influences development, disease risk, physical and mental health, and lifespan.

The Christina Lee Brown Envirome Institute is an affiliated research institute within the Division of Environmental Medicine. Researchers within the Envirome Institute study how conditions of the human envirome promote health or instigate disease.  Learn more about the Envirome Institute.




Pfeiffer, Jack A., et al. "The importance of urban planning: Views of greenness and open space is reversely associated with self-reported views and depressive symptoms." Population Medicine 3.July (2021): 1-11.

Depression, Urban greening, Views of greenness, Satisfaction with greenness7/15/2021

Petri, Belinda J., et al. "HNRNPA2B1 regulates tamoxifen-and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells.Cancer Letters (2021).

Breast cancer, Endocrine resistance, ER, Tamoxifen, Fulvestrant7/14/2021

Li, Xiaohong, et al. "Exposure to Fine Particulate Matter Air Pollution Alters mRNA and miRNA Expression in Bone Marrow-Derived Endothelial Progenitor Cells from Mice." Genes 12.7 (2021): 1058.

Air pollution, Endothelial progenitor cell, Cardiovascular disease7/10/2021

Li, Xiaohong, et al. "Adjusted Sample Size Calculation for RNA-seq Data in the Presence of Confounding Covariates." BioMedInformatics 1.2 (2021): 47-63.

RNA-seq, Sample size, Power, Monte Carlo simulation, FDR, Confounding covariates6/29/2021

Lin, Qian, et al. "Activating AMP-activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection from Nonalcoholic Fatty Liver Disease in Mice." Hepatology (Baltimore, Md.) 73.6 (2021): 2206.

Fibroblast growth factor 1, Nonalcoholic fatty liver disease, Nonalcoholic steatohepatitis, AMP-activated protein kinase, Nuclear factor erythroid 2-related factor 26/22/2021

Reynolds, Lindsay M., et al. "Tobacco Use Prevalence and Transitions From 2013 to 2018 Among Adults With a History of Cardiovascular Disease." Journal of the American Heart Association (2021): e021118.

Cardiovascular disease, Race and ethnicity, Smoking6/9/2021

Sansbury, Brian E., et al. "PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds." The American Journal of Pathology 191.6 (2021): 1049-1063.

Tissue injury, Inflammation, cys-SPM, PCTR16/1/2021

Tevis, Denise S., et al. "Harmonization of acronyms for volatile organic compound metabolites using a standardized naming system." International Journal of Hygiene and Environmental Health 235 (2021): 113749.

Biomonitoring, Volatile organic compounds, Volatile organic compound metabolites, Mercapturic acids, Naming systems, Acronyms6/1/2021

Stokes, Andrew C., et al. "Racial/Ethnic Differences in Associations of Non-cigarette Tobacco Product Use With Subsequent Initiation of Cigarettes in US Youths." Nicotine and Tobacco Research 23.6 (2021): 900-908.

Adolescent, Ethnic group, Hispanics or Latinos, Tobacco, Tobacco use, Cigarettes, Electronic cigarettes, Ethnic differences, Cigarette smoking6/1/2021

Majid, Sana, et al. "Lipid profiles in users of combustible and electronic cigarettes." Vascular Medicine (2021): 1358863X211009313.

E-cigarettes, Electronic cigarettes, Fasting glucose, Lipids, Smoking, Vaping5/20/2021

Alcaide, Pilar, and Steven P. Jones. "The Sweet Smell of Progress With Hyaluronan and Heart Failure." (2021): 1928-1930.

Heart Failure5/12/2021

Collins, Helen E., et al. "Mitochondrial Morphology and Mitophagy in Heart Diseases: Qualitative and Quantitative Analyses Using Transmission Electron Microscopy." Frontiers in Aging 2 (2021): 9.

Transmission electron microscopy, Heart, Heart failure, Myocardial infarction, Mitochondria, Autophagy, Mitophagy, Aging5/6/2021

Moore 4th, Joseph B., and Marcin Wysoczynski. "Immunomodulatory Effects of Cell Therapy after Myocardial Infarction."

Immunotherapy, Myocardial infarction, Heart attack, Coronary artery disease, Endothelial dysfunction, Vascular permeability


Raimundo, Rodrigo Daminello, et al. "Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated Subjects." Respiratory Care 66.5 (2021): 785-792.

Endotracheal aspiration, Airway resistance, Pulmonary compliance, Mechanical ventilation, Pulmonary pressure, Lung5/1/2021

McGraw, Katlyn E., et al. "Exposure to volatile organic compounds–acrolein, 1, 3-butadiene, and crotonaldehyde–is associated with vascular dysfunction." Environmental Research 196 (2021): 110903.

Volatile organic compounds, VOCs, VOC metabolites, Cardiovascular disease, CVD, Catecholamines, Endothelial function, Blood pressure, Pollution, Environmental health, Multipollutant, Mixture5/1/2021

Hill, Bradford G., et al. "Fine particulate matter (PM2. 5) inhalation-induced alterations in the plasma lipidome as promoters of vascular inflammation and insulin resistance." American Journal of Physiology-Heart and Circulatory Physiology 320.5 (2021): H1836-H1850.

Air pollution, Cardiovascular disease, Free fatty acids, Plasma metabolome, Pulmonary oxidative stress4/22/2021

Singh, Parul, et al. "Endothelial progenitor cells as critical mediators of environmental air pollution-induced cardiovascular toxicity." American Journal of Physiology-Heart and Circulatory Physiology 320.4 (2021): H1440-H1455.

Cardiovascular disease, Endothelial progenitor cells, Environmental air pollution, Fine particulate matter, PM2.5, Air pollution, Volatile air pollution4/7/2021

McNally, Lindsey A., et al. "Considerations for using isolated cell systems to understand cardiac metabolism and biology." Journal of Molecular and Cellular Cardiology (2021).

Glycolysis, Mitochondria, Catabolism, Anabolism, Heart failure, Cardiomyocyte4/1/2021

Fuqua, J. L., et al. "A rapid assessment of wastewater for genomic surveillance of SARS-CoV-2 variants at sewershed scale in Louisville, KY." medRxiv.

SARS-CoV-2, Wastewater, surveillance, Wastewater-based epidemiology, High-throughput sequencing3/26/2021

Oshunbade, Adebamike A., et al. "Cigarette smoking, incident coronary heart disease, and coronary artery calcification in black adults: The jackson heart study." Journal of the American Heart Association 10.7 (2021): e017320.

Cigarette smoking, Coronary artery calcification, Black adults, Jackson Heart Study, Coronary heart disease3/23/2021

Sonowal, Himangshu, et al. "Aldose reductase regulates doxorubicin-induced immune and inflammatory responses by activating mitochondrial biogenesis." European Journal of Pharmacology 895 (2021): 173884.

Chemotherapy and inflammation, Doxorubicin, Monocytes and macrophages3/15/2021

Weinstock, Ada, et al. "Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis." eLife 10: e67932.

IL4, STAT3, Wnt, Atherosclerosis resolution, Human, Immunology, Inflammation, Macrophages, Medicine, Mouse3/15/2021

Wood, Lindsey A., et al. "Time spent outdoors and sleep normality: A preliminary investigation." Population Medicine 3.March (2021): 1-6.

Sleep, Health risks, Nature, Time outdoors, Greenness


Keith, Rachel, and Aruni Bhatnagar. "Cardiorespiratory and Immunologic Effects of Electronic Cigarettes." Current Addiction Reports (2021): 1-11.

Electronic cigarettes, Tobacco, Nicotine, Cardiovascular disease, Pulmonary disease, Acquired and innate immunity


Riggs, Daniel W., et al. "Residential proximity to greenness mitigates the hemodynamic effects of ambient air pollution." American Journal of Physiology-Heart and Circulatory Physiology 320.3 (2021): H1102-H1111.

Air pollution, Arterial stiffness, Greenness, Ozone, PM2.53/2/2021

Farley, Gabrielle, et al. "Omega-3 polyunsaturated fatty acids modify the inverse association between systemic inflammation and cardiovascular fitness." Clinical Nutrition (2021).

Inflammation, Exercise, Omega-3, CRP, Cardiovascular2/11/2021

Tarran, Robert, et al. "E-cigarettes and Cardiopulmonary Health." Function 2.2 (2021): zqab004.

E-cigarette, Cardiovascular disease, Pulmonary disease, Policy, Cessation2/8/2021

Nong, Yibing, et al. "Echocardiography-guided percutaneous left ventricular intracavitary injection as a cell delivery approach in infarcted mice." Molecular and Cellular Biochemistry 476.5 (2021): 2135-2148.

Echocardiography guided, Intracavity injection, Cell therapy, Myocardial infarction, Mouse


Jin, Lexiao, et al. "Electronic Cigarette Solvents, Pulmonary Irritation and Endothelial Dysfunction: Role of Acetaldehyde and Formaldehyde." American Journal of Physiology-Heart and Circulatory Physiology (2021).

Aldehydes, Cardiovascular disease, Electronic cigarettes, Endothelium, Irritants, Tobacco2/5/2021

Kim, Thuy et al. “Disclosing Inspection Results at Point-of-Service: Affect of Characteristics of Food Establishment Inspection Programs on Foodborne Illness Outcomes.” Journal of Environmental Health 83.6 (2021): 8-13. 

Food safety, Environmental health, Restaurant inspection, Foodborne illness2/1/2021

O’Toole, Timothy E., et al. "Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Risk." International Journal of Molecular Sciences 22.3 (2021): 1383.

Carnosine, Acrolein, Cardiovascular disease, Biomarker1/30/2021

Ohanyan, Vahagn, et al. "Myocardial Blood Flow Control by Oxygen Sensing Vascular Kvβ Proteins." Circulation Research (2021).

Potassium channels, Coronary circulation, Physiology, Aldo-keto reductases, Ion channels1/27/2021

Fontenele, Rafaela S., et al. "High-throughput sequencing of SARS-CoV-2 in wastewater provides insights into circulating variants." medRxiv (2021).

SARS-CoV-2, Wastewater, surveillance, Wastewater-based epidemiology, High-throughput sequencing1/25/2021

Hosseini, Zeinab, et al. "Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation." Arteriosclerosis, Thrombosis, and Vascular Biology 41.3 (2021): 1062-1075.

Atherosclerosis, Necroptosis, Macrophage, Resolvin, Thromboxane1/21/2021

Solanki, Mitesh, et al. "Association of temporal trends in neutrophil lymphocyte ratio on left ventricular assist device patient outcomes." Artificial Organs (2021).

Heart failure, Left ventricular assist device, Neutrophil lymphocyte ratio1/12/2021

Smith, Ted, Gail Cassell, and Aruni Bhatnagar. "Wastewater Surveillance Can Have a Second Act in COVID-19 Vaccine Distribution." JAMA Health Forum. Vol. 2. No. 1. American Medical Association, 2021.

Infectious diseases, Coronavirus (COVID-19), Vaccination


O'Toole, Timothy E., et al. "Protocol: Protocol to assess the efficacy of carnosine supplementation in mitigating the adverse cardiovascular responses to particulate matter (PM) exposure: the Nucleophilic Defense Against PM Toxicity (NEAT) trial." BMJ Open 10.12 (2020).

Vascular medicine, Cardiology, Clinical trials, Toxicology, Cardiology12/28/2020

Abouleisa, Riham, et al. "Transient Cell Cycle Induction in Cardiomyocytes to Treat Ischemic Heart Failure." (2020).

Myocardial infarction (MI), Regenerative capacity


Mohamed, Tamer MA, and Daniel J. Conklin. "Emerging technology and platforms for cardiotoxicity testing." (2020): 115262.

Anticancer drugs, Cardiomyocyte, Embryonic stem cells, High throughput, Human-induced pluripotent stem cells, Toxicity


Dassanayaka, Sujith, et al. "Cardiomyocyte Oga haploinsufficiency increases O-GlcNAcylation but hastens ventricular dysfunction following myocardial infarction." Plos one 15.11 (2020): e0242250.

Heart, Heart failure, Cardiomyocytes, Cardiovascular physiology, Myocardial infarction, Echocardiography, Mouse models, Apoptosis


O’Toole, Timothy E., et al. "Urinary levels of the acrolein conjugates of carnosine are associated with inhaled toxicants." Inhalation Toxicology 32.13-14 (2020): 468-476.

Carnosine, PM2.5, Smoking, Acrolein, Biomarker


Heffron, Sean P., et al. "Platelet‐conditioned media induces an anti‐inflammatory macrophage phenotype through EP4." Journal of Thrombosis and Haemostasis 19.2 (2021): 562-573.

Atherosclerosis, Inflammation, Macrophages, Platelets, Prostaglandin E211/10/2020

Kaufman, Joel D., et al. "Guidance to reduce the cardiovascular burden of ambient air pollutants: a policy statement from the American Heart Association." Circulation 142.23 (2020): e432-e447.

Air pollution, Cardiovascular diseases, AHA Scientific Statements, Particulate matter, Policy making


Miller, Jessica M., et al. "Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity." Toxicology and Applied Pharmacology 406 (2020): 115213.

Antineoplastic Agents, Cardiotoxins, Doxorubicin, Trastuzumab, Apoptosis, Cardiotoxicity, Tissue Culture Techniques


Doherty Lyons, Shannon, et al. "Prenatal Exposure to Gutkha, a Globally Relevant Smokeless Tobacco Product, Induces Hepatic Changes in Adult Mice." International journal of environmental research and public health 17.21 (2020): 7895.

Smokeless tobacco, Developmental origins of health and disease, Gutkha, Hepatic, Liver disease10/28/2020

Irfan, Affan B., et al. "Smoking Accelerates Atrioventricular Conduction in Humans Concordant with Increased Dopamine Release." Cardiovascular toxicology (2020): 1-10.

Cigarette, Cotinine, Electrocardiography, Catecholamines, PR interval, PR segment, P wave, Atrioventricular, Smoking, Dopamine


Posa, Dheeraj Kumar, and Shahid P. Baba. "Intracellular pH Regulation of Skeletal Muscle in the Milieu of Insulin Signaling." Nutrients 12.10 (2020): 2910.

Carnosine, Chronic kidney disease, Diabetes, Glycolysis, Histidyl dipeptides, Insulin signaling, Intracellular pH, Obesity


Cave, Barbra, et al. "Working Toward elimination of Hepatitis C: The Kentucky Hepatitis academic Mentorship Program." Clinical Liver Disease 16.3 (2020): 123.

Hepatitis C, Public Health, Human Immunodeficiency Virus, HIV, Treatment, Injectable Drugs, Harm Reduction, Therapy


Bushau-Sprinkle, Adrienne, et al. "NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex." Antioxidants 9.9 (2020): 862.

Cellular redox state, Oxidative stress, Mitochondrial function, Cisplatin nephrotoxicity9/14/2020

Kang, Yi, et al. "Administration of cardiac mesenchymal cells modulates innate immunity in the acute phase of myocardial infarction in mice." Scientific Reports 10.1 (2020): 1-13.

Cardiac arrhythmia, Cardiac myocytes, Myocardium, Cardiovascular diseases, Teratoma, Embryonic stem cells, Heart diseases, Heart failure, Cancer, Fibrosis, Adult, Embryo, Transplant rejection, Primates, Therapeutic immunosuppression, Heart, Neoplasms, Transplantation, Stem cells, Pluripotent, Engraftment, Paracrine, Cell therapy, Clinical research, European society of cardiology, Enhanced s-cone syndrome


Lynch, Jordan, et al. "Acute and chronic vascular effects of inhaled crotonaldehyde in mice: Role of TRPA1." Toxicology and Applied Pharmacology 402 (2020): 115120.

Aldehydes, Blood pressure, Cigarettes, Endothelial dysfunction, Tobacco products, Transient receptor potential ankyrin-1


Rai, Shesh N., et al. "Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients." BMC medical research methodology 20.1 (2020): 1-16.

Composite outcomes, COVID-19, Efficacy, Hospitalization, Interim analysis, Intubation, Power, Mortality, Sample size, Toxicity monitoring


Lynch, Jordan, et al. "Tobacco Smoke and Endothelial Dysfunction: Role of Aldehydes?." Current Hypertension Reports 22.9 (2020): 1-9.

Acrolein, Aldehydes, Tobacco cigarettes, Electronic cigarettes, Electronic nicotine delivery systems, Endothelial dysfunction


Yeager, Ray A., et al. "Wastewater sample site selection to estimate geographically-resolved community prevalence of COVID-19: A research protocol." medRxiv (2020).

Wastewater based epidemiology, Wastewater, Sewer, COVID-19, SARS-CoV-2, Site Selection


Kaplin, Adam Ian, et al. "Evidence and magnitude of seasonality in SARS-CoV-2 transmission: Penny wise, pandemic foolish?." medRxiv (2020).

COVID-19, SARS-CoV-2, Temperature, Seasonality, Transmission


Baba, Shahid, et al. "Space Flight Diet-Induced Deficiency and Response to Gravity-Free Resistive Exercise." Nutrients 12.8 (2020): 2400.

Immune system, Microgravity, Ergogenic, Nutrition


Dong, Yunzhou, et al. "Epsin-mediated degradation of IP3R1 fuels atherosclerosis." Nature communications 11.1 (2020): 1-16.

Atherosclerosis, Endocytosis, Endosomes, Proteasome


Moore IV, Joseph B., et al. "The A-to-I RNA editing enzyme Adar1 is essential for normal embryonic cardiac growth and development." Circulation research 127.4 (2020): 550-552.

Cell death, High-throughput nucleotide sequencing, Myocardium, Myocytes, Cardiac, RNA editing7/31/2020

Wysoczynski, Marcin, et al. "Macrophage Long Non-Coding RNAs in Pathogenesis of Cardiovascular Disease." Non-coding RNA 6.3 (2020): 28.

Cardiovascular disease, Inflammation, lncRNA, Macrophage


Conroy, Lindsey R., et al. "Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells." Cancer cell international 20.1 (2020): 1-12.

RB, Palbociclib, Metabolism, Glutaminolysis, PPP, Lung cancer


Jin, L., et al. "Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1)." Toxicology and applied pharmacology 398 (2020): 115012.

Aldehydes, Crotonaldehyde (CR), Transient receptor potential ankyrin-1 (TRPA1), EDRF, Mesenteric artery, Nitric oxide (NO)7/1/2020

Audam, Timothy N., et al. "Cardiac mesenchymal cells from failing and nonfailing hearts limit ventricular dilation when administered late after infarction." American Journal of Physiology-Heart and Circulatory Physiology 319.1 (2020): H109-H122.

Cardiac repair, Cell therapy, Fibrosis, Ventricular remodeling6/24/2020

Sansbury, Brian E., et al. "Myeloid ALX/FPR2 regulates vascularization following tissue injury." Proceedings of the National Academy of Sciences 117.25 (2020): 14354-14364.

Macrophages, Ischemia, Resolvins6/23/2020

Zhao, Jingjing, et al. "Cardiospecific overexpression of ATPGD1 (carnosine synthase) increases histidine dipeptide levels and prevents myocardial ischemia reperfusion injury." Journal of the American Heart Association 9.12 (2020): e015222.

Carnosine, Balenine, Anserine, Carnosine synthase, Intracellular pH, Ischemia reperfusion, Acrolein


Kumar, Anupama, et al. "An Automated Mobile Mood Tracking Technology (Mood 24/7): Validation Study." JMIR Mental Health 7.5 (2020): e16237.

Depression, Text messaging, Patient monitoring, Mobile phone, Short message service, Ecological momentary assessment, Digital health5/20/2020

Wang, Kai, et al. "Endothelial overexpression of metallothionein prevents diabetes-induced impairment in ischemia angiogenesis through preservation of HIF-1α/SDF-1/VEGF signaling in endothelial progenitor cells." Diabetes 69.8 (2020): 1779-1792.

Diabetes, Oxidative stress, Endothelial progenitor cells, Endothelial regeneration, Metallothionein, Angiogenesis5/13/2020

Hammouda, K., et al. "A new framework for performing cardiac strain analysis from cine MRI imaging in mice." Scientific reports 10.1 (2020): 1-15.

Cardiology, Medical research


Casey, Joan A., et al. "Coal-fired power plant closures and retrofits reduce asthma morbidity in the local population." Nature Energy 5.5 (2020): 365-366.

Energy policy, Environmental impact, Environmental studies


Yeager, Ray A., Theodore R. Smith, and Aruni Bhatnagar. "Green environments and cardiovascular health." Trends in cardiovascular medicine 30.4 (2020): 241-246.

Prevention, Cardiovascular disease, Risk factors, Environment


Collins, Helen E., and John C. Chatham. "Regulation of cardiac O-GlcNAcylation: more than just nutrient availability." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866.5 (2020): 165712.

O-GlcNAc, O-GlcNAc transferase (OGT), O-GlcNAcase (OGA), Heart, Nutrient regulation, Metabolism, Cardiomyocyte, GFAT


Moore IV, Joseph B., and Shizuka Uchida. "Functional characterization of long noncoding RNAs." Current opinion in cardiology 35.3 (2020): 199-206.

Cardiovascular disease , Long noncoding RNAs , MicroRNAs


Sharma, Monika, et al. "Regulatory T cells license macrophage pro-resolving functions during atherosclerosis regression." Circulation research 127.3 (2020): 335-353.

Macrophages, Atherosclerosis, Inflammation, Immunity, Cardiovascular disease4/27/2020

Casey, Joan A., et al. "Improved asthma outcomes observed in the vicinity of coal power plant retirement, retrofit and conversion to natural gas." Nature energy 5.5 (2020): 398-408.

Energy and society, Environmental impact, Environmental studies


Liu, Min, et al. "Transcription Factor c-Maf Is a Checkpoint That Programs Macrophages in Lung Cancer." The Journal of clinical investigation 130.4 (2020): 2081-2096.

Cancer, Immunology, Immunotherapy, Macrophages4/1/2020

Yeager, Ray, et al. "Association between residential greenness and exposure to volatile organic compounds." Science of The Total Environment 707 (2020): 135435.

Greenness, VOC, NDVI, Pollution, Metabolites, Exposure


Basner, Mathias, Daniel W. Riggs, and Daniel J. Conklin. "Environmental determinants of hypertension and diabetes mellitus: sounding off about the effects of noise." (2020): e016048.

Hypertension, Editorials, Traffic, Noise, Air pollution, Sleep disturbance, Diabetes mellitus


Konkle, Stacey L., et al. "National secular trends in ambient air volatile organic compound levels and biomarkers of exposure in the United States." Environmental research 182 (2020): 108991.

Volatile organic compounds, VOCs, Air pollution, Secular trends, Environmental health, NHANES, Biomarkers of exposure


Keith, Rachel J., et al. "Characterization of volatile organic compound metabolites in cigarette smokers, electronic nicotine device users, dual users, and nonusers of tobacco." Nicotine and Tobacco Research 22.2 (2020): 264-272.

Nicotine, Tobacco, Volatile organic compounds, Metabolites, Cigarettes, Smokers


Carll, Alex P., et al. "Inhalation of printer-emitted particles impairs cardiac conduction, hemodynamics, and autonomic regulation and induces arrhythmia and electrical remodeling in rats." Particle and fibre toxicology 17.1 (2020): 1-21.

Arrhythmia, Particulate matter, Autonomic, Electrocardiogram, Cardiac, Nanoparticles, Printers, Telemetry, Left ventricular pressure, Contractility, Repolarization, Electrical remodeling


Li, Xiaohong, et al. "Choice of library size normalization and statistical methods for differential gene expression analysis in balanced two-group comparisons for RNA-seq studies." BMC genomics 21.1 (2020): 1-17.

RNA-seq, Sample sizes, Normalization, Statistical test, Differentially expressed genes


Conroy, Lindsey R., et al. "Loss of Rb1 enhances glycolytic metabolism in Kras-driven lung tumors in vivo." Cancers 12.1 (2020): 237.

Rb1, Metabolomics, Glycolysis, TCA anaplerosis, Lung cancer1/17/2020

Heidel, Justin S., et al. "The effect of cardiogenic factors on cardiac mesenchymal cell anti-fibrogenic paracrine signaling and therapeutic performance." Theranostics 10.4 (2020): 1514.

Cardiac Mesenchymal Cells, Fibrosis, Myocardial Infarction, Paracrine Signaling, Therapy1/1/2020

Riggs, Daniel W., et al. "Exposure to airborne fine particulate matter is associated with impaired endothelial function and biomarkers of oxidative stress and inflammation." Environmental research 180 (2020): 108890.

Air pollution, Endothelial dysfunction, PM2.5, Isoprostanes, Reactive hyperemia index, Cytokines