Mark S. Slaughter, M.D.

Professor and Chair, Department Cardiovascular and Thoracic Surgery

Executive Medical Director, UofL Health - Jewish Hospital

Director, Heart Transplant and Mechanical Assist Device, University of Louisville, UofL Health - Jewish Hospital

Special interests

  • Clinical research trials in thoracic surgery
  • Training future leaders in thoracic surgery


  • Medical degree – Indiana University School of Medicine, Bloomington, IN
  • General surgery residency – McGaw Medical Center, Northwestern University, Chicago, IL
  • Cardiovascular and thoracic surgery fellowship – University of Minnesota Medical Center, Minneapolis, MN


  • American Board of Surgery
  • American Board of Thoracic Surgery

Professional activities

  • Board of Directors for the American Society of Artificial Internal Organs (ASAIO)
  • Board of Trustees for the International Society of Rotary Blood Pumps
  • Editorial Board of American Society for Artificial Internal Organs
  • Consultant to the US FDA Medical Device Review Panel
  • Grant reviewer for US National Science Foundation SBIR/STTR
  • Past member of the US Health and Human Services Medicare Coverage Advisory Committee
  • Reviewer for the following journals: Annals of Thoracic Surgery, Circulation and Journal of Heart and Lung Transplantation
  • Visiting professor at various universities
  • Guest speaker at numerous national and international conferences
  • Author of numerous peer-reviewed articles in medical journals, book author, and author of book chapters
  • Awarded 2010 ARGI Physician of the Year by Medical News
  • Named Science Ambassador for the Louisville Science Center in 2009.


Learn about our Advanced Heart Failure Research (AHFR) Program 


Recent Publications:

    1. Tsiouris A, Slaughter MS, Jeyakumar AKC, Protos AN. Left ventricular assist devices: yesterday, today, and tomorrow. J Artif Organs. 2024 Mar 7. doi: 10.1007/s10047-024-01436-0.

    2. Endo T, Peters MG, Hopkins CD, Slaughter MS, Miller KR. Management of contained penetrating cardiac injury in a patient with prior cardiac surgery. BMJ Case Rep. 2024 Mar 5;17(3):e257855. doi: 10.1136/bcr-2023-257855.

    3. Gallo M, Slaughter MS, Trivedi JR. Donor heart preservation with controlled hypothermic technology: Insights into the data. J Heart Lung Transplant. 2024 Feb 17:S1053-2498(24)00053-6. doi: 10.1016/j.healun.2024.02.012.

    4. Sweeney JC, Trivedi JR, Endo T, Ankem A, Pahwa SV, Slaughter MS, Ganzel BL. Cannula Placement for Cerebral Protection Without Circulatory Arrest in Patients Undergoing Hemiarch Aortic Aneurysm Repair. Tex Heart Inst J. 2024 Feb 12;51(1):e228026.

    5. Trivedi JR, Endo T, Sharma A, Fox MP, Slaughter MS, van Berkel VH. Ambulatory Extracorporeal Membrane Oxygenation Use in Patients Listed for Lung Transplant. ASAIO J. 2024 Feb 2. doi: 10.1097/MAT.0000000000002154

    6. Gemelli M, Addonizio M, Geatti V, Gallo M, Dixon LK, Slaughter MS, Gerosa G. Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery. Med Sci (Basel). 2024 Jan 11;12(1):6. doi: 10.3390/medsci12010006.

    7. Sabharwal A, Tsiouris A, Slaughter MS, Lemor A, Jeyakumar AKC, Protos A, Hernandez GA. Left Atrial-Veno Arterial Extracorporeal Membrane Oxygenation as a Bridge to Surgery for Endocarditis-Related Acute Severe Aortic Regurgitation. ASAIO J. 2023 Nov 2. doi: 10.1097/MAT.0000000000002077.

    8. Trivedi J, Pahwa S, Rabkin D, Gallo M, Guglin M, Slaughter MS, Abramov D. Predictors of Survival After Heart Transplant in the New Allocation System: A UNOS Database Analysis. ASAIO J. 2024 Feb 1;70(2):124-130. doi: 10.1097/MAT.0000000000002070.

    9. Gemelli M, Gallo M, Addonizio M, Van den Eynde J, Pradegan N, Danesi TH, Pahwa S, Dixon LK, Slaughter MS, Gerosa G. Surgical Ablation for Atrial Fibrillation During Mitral Valve Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Cardiol. 2023 Dec 15;209:104-113. doi: 10.1016/j.amjcard.2023.09.088.