Amanda LeBlanc, Ph.D.

 

Interim Associate Dean of Research, UofL School of Medicine
Professor, tenure,
 Department Cardiovascular and Thoracic Surgery

 https://leblanclaboratory.com/

Education

  • Ph.D. in Exercise Physiology, West Virginia University (2008)
  • M.S. in Exercise Physiology, University of Louisville (2004)
  • B.S. in Kinesiology, Indiana University (2002)
  • Postdoctoral Associate, Cardiovascular Innovation Institute, Jewish Hospital and University of Louisville (2011)
  • Postdoctoral Fellow, Center for Cardiovascular and Respiratory Research, West Virginia University (2009)

Selected Publications

  • Tracy EP, Nair R, Rowe G, Beare JE, Beyer A, LeBlanc AJ. Adipose stromal vascular fraction reverses mitochondrial dysfunction and hyperfission in aging-induced coronary microvascular disease. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H749-H762. doi: 10.1152/ajpheart.00311.2022. Epub 2022 Aug 26. PMID: 36018760; PMCID: PMC9529257.
  • SenthilKumar G, Gutierrez Huerta CA, Freed JK, Beyer AM, FancherIS, LeBlanc AJ.New Developments in Translational Microcirculatory Research. Am J Physiol Heart Circ Physiol. 2022 Oct 28. doi: 10.1152/ajpheart.00566.2022. Epub ahead of print. PMID: 36306213.
  • Tracy EP, Rowe G, LeBlanc AJ. Cell therapy-induced recovery of dysfunctional microvasculature. Aging (Albany NY). 2022 Jul 13;14(13):5296-5298. doi: 10.18632/aging.204183. Epub 2022 Jul 13. PMID: 35832022; PMCID: PMC9320541.
  • Tracy EP, Dukes M, Beare J, Rowe G, Nair R, LeBlanc AJ. Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease. Antioxid Redox Signal. 2022 Aug 11. PMID: 35950616.
  • Rowe G, Heng DS, Beare JE, Hodges NA, Tracy EP, Murfee WL, LeBlanc AJ.Stromal Vascular Fraction Reverses the Age-Related Impairment in Revascularization following Injury. J Vasc Res. 2022;59(6):343-357. doi: 10.1159/000526002. Epub 2022 Sep 8. PMID: 36075199; PMCID: PMC9780192
  • Rowe G, Tracy E, Beare JE, LeBlanc AJ. Cell therapy rescues aging-induced beta-1 adrenergic receptor and GRK2 dysfunction in the coronary microcirculation. Geroscience. 2022 Feb;44(1):329-348. doi: 10.1007/s11357-021-00455-6. Epub 2021 Oct 4. PMID: 34608562; PMCID: PMC8811091
Areas of Interest

  • Coronary microvascular dysfunction
  • Regenerative medicine utilizing adipose-derived stromal cells
  • The effect of aging on the cardiovascular system
  • Mitochondrial signaling in the vascular wall