News
Back-to-back celebrations honor faculty and staff excellence at the ULSOM
Excitement and pride filled the air as the University of Louisville School of Medicine recently celebrated the extraordinary contributions of its faculty and staff during two evenings of recognition. The 9th celebration of staff excellence took place on December 3, with the 6th celebration of faculty excellence the following evening on December 4.
These back-to-back events highlighted the individuals who continue to distinguish the School of Medicine through their unwavering dedication to education, research, patient care, and community engagement.
The 2024 Dean’s Staff Excellence Awards honored staff members whose work exemplifies the mission of the School of Medicine. These awards recognize the vital contributions of staff in fostering a supportive, inclusive, and innovate environment for students, patients, and researchers alike.
“As we reflect on the past year, it’s clear the work of our staff, both visible and behind the scenes, is essential to our success as an institution,” said Jeffrey Bumpous, dean of the School of Medicine. “We are immensely proud of the staff we recognized this year, who demonstrate excellence daily in service to our mission.”
Cardinal Spirit Award – Ignacio Bravo Rojas
Commitment to an Inclusive Community Award – Sharon Gordon
Community Impact Award – Jan Ke-McCue
Team Impact Award – Academic Technology Office and Brown Cancer Center Clinical Trials Team
Dean’s Lifetime Achievement Award – Maurice Eichenberger
Heart of the School – Ruby Keith
New Professionals Award – Dr. Maya Lynum-Walker
Performance Excellence Award in an Administrative Office – Hao Zhang
Performance Excellence Award in a Basic Sciences Department – Colleen Quinter
Performance Excellence Award in a Clinical Sciences Department – Elizabeth Welsh
Faculty Awards
On the following evening, the 6th celebration of Faculty Excellence honored faculty members whose remarkable achievements advance the mission of the School of Medicine. Faculty were recognized for their dedication to their areas of service, teaching, research, and inclusive excellence initiatives. In addition to the 13 award winners, the event also honored 60 individuals who were promoted and/or newly tenured, four new endowed chairs, and 40 award nominees.
“There is no question that our faculty are some of the most committed and talented medical professionals in the nation,” said Dr. Michelle Stevenson, vice dean for Faculty Affairs. “Our outstanding faculty demonstrate excellence and leadership as we teach, serve others, and conduct groundbreaking research, right here at the University of Louisville School of Medicine. We are deeply committed to honoring their achievements and supporting and celebrating their successes.”
Career Achievement in Research – Jon B. Klein, M.D., Ph.D.
Career Achievement in Distinguished Service – Vicki Montgomery, M.D.
Career Achievement in Education – Jennifer Brueckner-Collins, Ph.D.
Diversity, Equity & Inclusion Champion – La Creis R. Kidd, Ph.D., M.P.H.
Leonard Tow Humanism in Medicine Award sponsored by the Arnold P. Gold Foundation – Brittany Badal, M.D.
Outstanding Multicultural Education – Daniela Terson de Paleville, Ph.D.
Outstanding Educator – Christopher Barton, M.D.
Outstanding Education by Gratis Faculty – Adam C. Neff, M.D.
Outstanding Research in Basic & Applied Sciences – Jiapeng Huang, M.D., Ph.D.
Distinguished Service to Community, The Commonwealth & Region – Alexander Bautista, M.D.
Distinguished Service in the National/International Community – Jackson Williams, M.D.
Distinguished Service to the Profession – Charles Scoggins, M.D., M.B.A.
Distinguished Service to the University of Louisville – Forest Arnold, D.O.
The School of Medicine is proud to celebrate these remarkable faculty and staff who continually elevate the institution’s reputation. Congratulations to all of the 2024 award recipients! We look forward to even more accomplishments in the year ahead.
Dr. In Kim appointed vice dean of Innovation and Strategy at the ULSOM
In K. Kim, M.D., vice dean of Innovation and Strategy and associate vice president of Health Affairs
The School of Medicine is pleased to announce In K. Kim, MD as the new vice dean of Innovation and Strategy and associate vice president of Health Affairs.
In his new role, Kim will oversee and guide the Office of Strategy and Innovation, facilitating key strategic projects for both the School of Medicine and the Health Sciences Campus. He will play a critical role in supporting decision-making and shaping strategies that align with the institution’s growth and innovative goals.
“I am honored to serve the School of Medicine and Health Sciences Campus in this new capacity,” said Kim. “At a time when innovation and strategic thinking are more vital than ever, I am honored to be the voice of those very imperative objectives.”
Kim’s professional background began at the Cornell University, followed by his tenure at Weill Cornell Medical College. After completing his residency at St. Christopher’s Hospital for Children in Philadelphia, Kim pursued fellowship training in pediatric emergency medicine at the Children’s Hospital of Pittsburgh. He later earned an master’s in business administration from the University of Louisville, deepening his involvement with the College of Business.
In addition to his international recognition for the research of helium-oxygen therapies for pediatric respiratory diseases, Kim is known for his comprehensive array of profoundly impactful positions, including director of the Center for Health Process Innovation, co-director of the Business and Leadership Distinction Track, co-director of Bluegrass Biodesign, and program director of the UofL MD-MBA program.
As executive vice chair in the department of Pediatrics and the executive medical director for the Norton Children’s Medical Group, Kim has demonstrated a deep commitment to enhancing patient outcomes and upholding high standards of care in pediatric medicine.
“Dr. Kim’s inspiring career and dedication to innovative healthcare solutions make him an invaluable addition to this role,” said Dean Jeffrey Bumpous. “I am confident that he will excel in this role as he expands on the high caliber of innovation and strategy at our institution.”
Dr. Kim accepted his new responsibilities effective October 1. Please join us in congratulating him on his new role!
UofL launches new program aimed at helping biomedical students innovate
Students participating in the Bluegrass Biodesign program. The program is a nine-month training course where students gain hands-on experience creating and testing their ideas in the real world.
The University of Louisville has launched a new entrepreneurship program aimed at helping students develop innovations that save and improve lives.
The Bluegrass Biodesign program is a nine-month training course where students gain hands-on experience creating and testing their ideas in the real world. The curriculum includes opportunities to prototype new designs while participating in workshops and lectures led by faculty at the UofL School of Medicine, College of Business and J.B. Speed School of Engineering.
“This is about training the next generation of innovators in health care and medicine,” said In Kim, a professor of pediatric medicine and program lead. “With Bluegrass Biodesign, we hope to equip UofL students with the tools they need to launch technologies that can save lives.”
Students complete the program in multidisciplinary teams, each blending undergraduate and graduate students in medicine and engineering. The idea is that they each bring insights from their own area of expertise that could help them solve problems and innovate.
“What we find is that innovation is a team sport,” said Beth Spurlin, an associate professor and co-director of the program. “The best solutions come from different people with different perspectives working together. With Bluegrass Biodesign, we give students the opportunity to experience that before they even leave campus.”
Eight teams — a total of 58 students —participated in the 2024-2025 cohort. Logan Davis, an M.D./MBA student, said the experience taught him just how much work goes into developing the innovations his patients will one day rely on. His team worked on a device to help patients who struggle with both urinary control and motor tremor and/or dexterity. The solution for the former is to self-catheterize, which can be difficult without full control of your hands or arms.
“We wanted to target this set of problems to give back some comfort and autonomy to these patients,” said Davis, who also was co-president for the 2023-2024 cohort. “This is a process I am so thankful to have been a part of, and I plan on using the biodesign process Bluegrass BioDesign is based on for the rest of my career to design/improve care for all of my patients.”
The student teams also complete business training via LaunchIt, the office’s accelerated entrepreneurial bootcamp that is part of UofL’s National Science Foundation Innovation Corps (I-Corps) program, housed in the UofL Office or Research and Innovation. In the 2024 cycle, all eight teams received $3,000 in funding, along with mentorship and training, via the I-Corps program.
“We are thrilled to formalize the collaboration between Bluegrass Biodesign and UofL's I-Corps program,” said Jessica Sharon, senior director of innovation programs and new ventures, who leads I-Corps and LaunchIt. “We are proud of these students' hard work in the program to identify and validate market needs they are working to solve!”
Applications for the next cycle of Bluegrass bioDesign will be open for submission at the beginning of the spring 2025 semester. Learn more and apply here.
Damian Shin, Ph.D., appointed Chair of Anatomical Sciences and Neurobiology
The University of Louisville School of Medicine (ULSOM) is excited to announce Damian Shin, Ph.D., as the new Chair of Anatomical Sciences and Neurobiology.
As Chair, Dr. Shin will oversee the department’s educational and research programs, guiding its strategic growth and fostering innovation across initiatives.
“Joining the University of Louisville School of Medicine is a phenomenal step in my career,” said Dr. Shin. “The work being done at the School of Medicine is a true inspiration and it is an honor to bring my own ideas and contributions to such an impactful team.”
Dr. Shin is a distinguished scholar who earned an Honors Bachelor of Science in Biology and a Master of Science in Physiology from the University of Western Ontario, along with a Ph.D. in Neurophysiology from the University of Toronto. He further refined his expertise during a postdoctoral fellowship at the Division of Fundamental Neurobiology at Toronto Western Hospital.
Over the past 15 years, Dr. Shin has held several key positions at Albany Medical College, including his most recent role as Interim Chair and Professor in the Department of Neuroscience & Experimental Therapeutics.
“Dr. Shin’s impressive academic and professional background makes him an excellent fit to build on the cutting-edge biomedical neurosciences research and professional education that is present and expanding at the School of Medicine and in the department of Anatomical Sciences and Neurobiology,” said Jeffrey Bumpous, MD, dean of the School of Medicine. “We are thrilled to welcome him to the UofL family.”
Please join the School of Medicine in welcoming Dr. Shin, whose official appointment will begin December 9.
Joint Pilot Project Receives Internal Funding
Katie Cardarelli, Dean of the School of Public Health & Information Sciences (SPHIS), and Jeffrey Bumpous, Dean of the School of Medicine (SOM), developed the Joint Pilot Project Program with $250,000 to support novel, collaborative research projects forming the basis for new NIH ROI grant applications. The Joint Pilot Project Program offers valuable resources for SOM and SPHIS investigators to tackle pressing health and public health challenges.
“Establishing this initiative and funding four joint pilot projects underscores our commitment to expanding transdisciplinary research. A key part of that is fostering strong relationships across schools and growing our NIH portfolio. Together, we are ready to elevate the impact of our research in Louisville and beyond,” said Dr. Cardarelli.
The awardee selection process was established and managed by SOM’s Vice Dean of Research, J. Christopher States, and SPHIS’ Associate Dean for Research, W. Paul McKinney. In response to the RFA announcement, faculty submitted 15 letters of intent; eight (8) projects were invited to submit full proposals. A panel of six faculty from SPHIS and SOM scored the proposals (listed below), and four joint projects were selected for funding.
“The research activities involved with these projects underscores the immeasurable talents we have at the University of Louisville. Our physician scientists are leading the way in cutting-edge discoveries that will improve the health and well-being of our community, Commonwealth and world. I am honored to have the opportunity to support such impactful work,” said Dr. Bumpous.
Congratulations to the following researchers who received pilot project funding to support four unique initiatives that launched in October 2024 and will run through December 2025. These awardees are expected to submit an NIH grant proposal using data from their pilot projects by June 30, 2026.
PROJECTS & INVESTIGATORS
Integrating artificial intelligence and gene editing to identify and validate epigenetic targets for nutrient-based interventions in fetal alcohol spectrum disorder
- Shao-yu Chen, PhD, Professor & Distinguished Scholar, Dept. of Pharmacology & Toxicology, School of Medicine
- Shuoyang Wang, PhD, Assistant Professor, Dept. of Bioinformatics and Biostatistics, School of Public Health & Information Sciences
Exposome approach to environmental carcinogen exposures and breast cancer incidence
- Lu Cai, Professor, MD, MPH, Professor, Depts. of Pediatrics, Radiation Oncology, Pharmacology & Toxicology; Director, Pediatric Research Institute; School of Medicine
- Natalie DuPré, ScD, MS, Assistant Professor, Dept. of Epidemiology & Population Health, School of Public Health & Information Sciences
Development of a novel intervention to improve treatment of liver disease in rural communities
- Michael E. Egger, MD, MPH, Associate Professor, Department of Surgery, School of Medicine
- Seyed Karimi, PhD, Associate Professor, Dept. of Health Management & Systems Sciences, School of Public Health & Information Sciences
Individual and Structural Factors of Prescription Weight Loss Drug Misuse Among People with Eating Disorders
- Cheri Levinson, PhD, Professor, Dept. of Psychological & Brain Sciences; Dept. of Pediatrics, School of Medicine
- Nicholas Peiper, PhD, MPH, Associate Professor, Epidemiology & Population Health, School of Public Health & Information Sciences
PROPOSAL REVIEWERS
- Richard Baumgartner, PhD, Professor and Chair, Dept. of Epidemiology & Population Health
- Amanda Jo LeBlanc, PhD, FAHA, Professor, Dept. of Cardiovascular and Thoracic Surgery; Cardiovascular Innovation Institute; Pilot Project Program Director, Center for Integrative Environmental Health Sciences; Interim Associate Dean of Research, School of Medicine; Interim Associate Dean of Research, School of Nursing
- Maureen McCall, PhD, Professor, Dept. of Ophthalmology and Visual Sciences; Chair of the School of Medicine Research Committee
- Bert Little, PhD, Professor, Dept. of Health Management & Systems Sciences
- Jelani Kerr, PhD, Associate Professor and Interim Chair, Dept. of Health Promotion & Behavioral Sciences
- KB Kulasekera, PhD, Professor and Chair, Dept. of Bioinformatics & Biostatistics
ULSOM recognizes inspiring student journey in honor of National First-Generation Day
Becoming a physician is a challenging path for any medical student, but first-generation students face additional hurdles as they navigate the complexities of higher education for the first time in their families.
Parris Kapple, a fourth-year student at the University of Louisville School of Medicine (ULSOM), began her journey with a Bachelor of Arts in Psychology on a Pre-Med track at Bellarmine University. Now, she’s achieving her dreams at ULSOM while actively volunteering with programs like Future Healers, a student-led initiative supporting community health. As a first-generation student, Parris has overcome unique obstacles on her way to earning an M.D.
Medicine wasn’t always Parris’ goal. She originally had her mind set on nursing, but a clinical rotation observation with an interventional radiologist changed her perspective. Inspired by the patient care she witnessed, Parris switched her focus to medicine, a choice that required her to adjust her academic path and fulfill pre-med requirements.
“As a first-generation college student from a community where few people become doctors, pursuing medicine felt as far-fetched as becoming an astronaut,” said Kapple. “Still, I decided to go for it.”
Parris, who grew up in South Louisville, chose ULSOM for its reputation and deep-rooted commitment to serving the community. She has been able to give back to her own community while being surrounded by a supportive network of family and mentors, including ULSOM alum, Dr. Suzanne McGee. The guidance from ULSOM faculty and residents has provided Parris with valuable insights into the profession.
“The UofL School of Medicine is the perfect environment for first-generation students who are looking to pour back into communities while receiving support of their own,” said Tony Simms, M.P.H., director of Medical Student Affairs & Student Wellness. “We are proud to cultivate an inclusive community that equips students from all backgrounds to become resilient, compassionate physicians.”
Parris’ background as a first-generation student has fostered a unique connection with her patients. As her patients work to navigate an ever-complex health care system, she is navigating the systems of higher education. As she works through the demands of medical education, she’s committed to ensuring her patients feel heard, respected, and valued – a perspective she brings to each interaction.
Now preparing for a urology residency, Parris is inspired by the mentors who supported her journey and hopes to be a source of mentorship for future medical students. She understands the importance of having someone who believes in you, especially as a first-generation student, and aspires to show future students that a career in medicine is possible regardless of the challenges they face.
Parris encourages other first-generation students to seek out mentors who recognize their potential and stay true to the values that sparked their passion for medicine. She also reminds peers of the importance of reflecting on their progress and growth.
“Watching first-generation students like Parris thrive in medical school is incredibly rewarding,” said Monica Ann Shaw, M.D., M.A., FACP, vice dean of Undergraduate Medical Education. “Being a first-generation student in medical school is nothing short of inspiring, and the UofL School of Medicine is proud to support their educational journey, from application to graduation.”
In celebration of National First-Generation Day, ULSOM is proud to honor the achievements of its first-generation students like Parris, who embody the school’s mission to educate compassionate physicians, dedicated researchers, and committed community leaders.
UofL medical student advocates for equitable health care
The Centers for Disease Control (CDC) defines health disparities as preventable differences in the burden of disease, injury, violence, or opportunities to achieve optimal health. Resulting from multiple factors, including poverty, environmental threats, among others, health disparities are related to unequal distribution of social, political, economic, and environmental resources.
UofL News talked with fourth-year UofL medical student Sierra Shockley about her commitment to addressing health disparities as a Health and Social Justice Scholar (HSJS). Recently selected by the American Lung Association to represent the organization at Respiratory Advocacy Day in Washington, D.C., Shockley met with legislators to address disparities in lung health. Her ongoing advocacy work as a HSJS gave her the chance to not only represent the American Lung Association, but also the University of Louisville.
UofL News: Tell us about your involvement with the Health and Social Justice Scholar (HSJS) program.
What truly excites me about this program is its emphasis on interdisciplinary collaboration, fostering partnerships between students from various professional and doctoral programs, all working together to tackle the most pressing health inequities. Participating in this program has also challenged me to reflect on my role as a future physician, not just in treating patients but in advocating for systemic change.
UofL News: Why is it so important to address health disparities?
Shockley: Health disparities are not just medical problems—they are societal and reflect deep-rooted inequalities that need to be confronted if we are to create a more just and equitable health care system. It’s about making sure that healthcare is fair and accessible to all, no matter where people live or who they are.
It’s a stark reality that something as simple as a zip code can determine a person’s health outcomes, with life expectancy sometimes varying by more than ten years within just a 20-30-mile locational difference. This geographic inequality is just one example of how pervasive and alarming health disparities are. For instance, people of certain racial or ethnic backgrounds are more likely to face higher rates of morbidity and mortality for conditions such as diabetes, hypertension, and asthma, simply because of the systemic barriers that exist in their communities.
UofL Health: How can health equity be advanced through community participatory research?
Shockley: Community-based participatory research (CBPR) involves engaging the communities affected by health disparities in every step of the process, from identifying the problems to developing solutions. CBPR allows for a more inclusive and comprehensive approach to tackling disparities, creating interventions that are both culturally relevant and practically applicable. This approach also helps ensure that the research is actionable, impactful, and sustainable while fostering a sense of trust and ownership within the community as they see that their voices and lived experiences are being valued in the research process.
UofL News: Tell me about your experience in Washington D.C. What was your biggest takeaway?
Shockley: My experience standing for the University of Louisville in Washington D.C. was both inspiring and transformative. The biggest takeaway was the profound impact that storytelling and personal narratives can have when advocating for change. While data and research are crucial, it’s often the emotional and human aspects of a story that resonate most with lawmakers.
This experience also highlighted the power of collaboration—whether it’s with fellow advocates, policymakers, or health care professionals. By working together, we were able to amplify our voices and drive home the importance of lung health on a broader scale.
UofL News: How do you plan to use your research/knowledge about health disparities in your medical career/practice?
Shockley: I am fortunate to be working with Dr. Scott Bickel and Dr. Rose Hawkins on a project analyzing the impact of urban greening on asthma exacerbations and related health outcomes. By studying how urban green spaces can mitigate asthma symptoms and improve respiratory health, I am gaining valuable insight into how environmental justice is tied to health equity, and this knowledge will undoubtedly influence how I approach patient care.
As a future surgeon, knowing many underserved communities face significant barriers to accessing surgical care, I hope to focus part of my career on bridging that gap. Whether through global health initiatives, public health programs, or working with underserved populations locally, I aim to be an advocate for systemic change, ensuring that the communities I serve have access to the resources and infrastructure necessary to lead healthier lives.
LGBTQ+ Affirming Healthcare Series drives efforts to reduce healthcare disparities
The UofL School of Medicine (ULSOM) remains steadfast in its mission to reduce healthcare disparities and foster an inclusive healthcare environment for all. Through the LGBTQ+ Affirming Healthcare Series facilitated by the UofL LGBT Center, the school seeks to strengthen healthcare access and support for the LGBTQ+ community, empowering providers with tools for inclusive, affirming care.
The latest session in the series featured Pride Keynote speaker Britney Daniels, MSN, RN, who delivered a compelling presentation titled Beyond Inclusion: Cultivating Queer Conscious Healthcare Practices on October 17. Daniels, an author and emergency room nurse, drew from her career to illuminate the unique challenges faced by LGBTQ+ individuals and the critical need for equitable healthcare practices. This session marked the second in the 2024-2025 series, and Daniels’ perspective, also shared in her book Journal of a Black Queer Nurse, resonated powerfully with attendees, highlighting the systemic change needed to create safe and affirming healthcare spaces.
Structured across six in-depth training sessions and three interactive patient simulation modules, the LGBTQ+ Affirming Healthcare Series equips healthcare students, professionals, and others committed to addressing LGBTQ+ health disparities with the essential skills needed to affirm, advocate, and improve health outcomes for LGBTQ+ patients.
“Every day, the School of Medicine commits to initiatives that address the healthcare disparities we encounter,” said Jeffrey Bumpous, Executive Vice President for Health Affairs and dean of the School of Medicine. “Our contribution to the LGBTQ+ Affirming Healthcare series exemplifies this commitment and reflects our dedication to positive systemic change.”
Participants in the series have the opportunity to earn a Certificate of Completion by attending at least four training sessions in person, hybrid, or asynchronously, along with completing three online patient simulation modules and reflections by March 31, 2025. Additionally, Continuing Medical Education (CME) credits are available to eligible attendees.
The next session in the series, scheduled for November 14 at noon, will feature Brittney Richardson, MD, assistant dean of Admissions, who will lead a presentation focused on furthering equitable healthcare practices. ULSOM students, staff, and faculty are encouraged to attend in support of Dr. Richardson’s message and to continue building momentum within this transformative series.
“The progress seen from the LGBTQ+ Affirming Healthcare Series is inspiring,” said Dr. Richardson. “I am deeply honored to contribute to this movement as we work to reduce disparities in healthcare, for both patients and providers.”
In celebration of LGBTQ+ History Month, ULSOM proudly participates in this university-wide effort to advance health equity. The dedication of students, staff, and faculty reinforces our commitment to creating an inclusive and affirming environment for all.
Interested in registering for Dr. Richardson’s installment of the LGBTQ+ Affirming Healthcare Series? Fill out the interest form.
ULSOM student receives KYNETIC grant for cutting-edge technology
University of Louisville School of Medicine (ULSOM) second-year student, Connor Centner, Ph.D., has been awarded the KYNETIC (Kentucky Network for Innovation and Commercialization) grant as a Principal Investigator for his groundbreaking work in biomedical technology.
KYNETIC, funded by the National Institute of Health’s Research Evaluation and Commercialization Hub (REACH) program supports innovative health care-related product development projects led by faculty, staff, students, and trainees from Kentucky colleges and universities. The program accelerates the commercialization of cutting-edge technologies that address unmet human health needs.
Before enrolling in the ULSOM, Centner earned his Ph.D. in Translational Bioengineering from the University of Louisville and completed a postdoctoral fellowship in the department of Radiology at the University of Chicago (UChicago). While at UChicago, he was a member of the Comprehensive Cancer Center that focused on advancing next-generation histotripsy – a noninvasive, non-thermal ultrasound technology used to destroy tumors. His expertise in this emerging field earned him the prestigious F. V. Hunt Postdoctoral Research Fellowship, recognizing his work as one of the few specialists worldwide in histotripsy.
Centner is now focused on commercializing his histotripsy technology, which has the potential to revolutionize cancer care. “It is truly an honor to be the recipient of the KYNETIC grant as I continue working towards the commercialization of this cutting-edge technology,” said Centner. “The support provided by KYNETIC will have a significant impact on the future of cancer treatment.”
KYNETIC accelerates the introduction of projects like Centner’s by developing technological infrastructure, allocating funding for product definition studies, offering access to experts and mentors, offering entrepreneurial skills development, and assisting in the development of commercialization strategies.
“Dr. Centner is an exceptionally talented young scientist, and his work in translational science holds tremendous promise,” said Olivia Mittel, M.D., associate dean for Student Affairs. “The potential impact of his technology on patient outcomes is profound.”
ULSOM is proud of Dr. Centner’s achievements and commitment to improving health outcomes. Congratulations, Dr. Centner, for your remarkable contributions to the future of medicine!
ULSOM Supports Learner Success During Annual Raise Some L
Raise Some L, the University of Louisville’s annual day of giving, kicked off last night, October 15 at 6:02 p.m. for 1,798 minutes of celebrating and supporting the stories and journeys of the UofL community. Raise Some L will continue through midnight tonight, October 16.
At the University of Louisville School of Medicine (ULSOM), this year’s Raise Some L is dedicated to advancing the success of our learners. From medical students to residents to fellows, each benefits significantly from direct learner success initiatives and the broader support of ULSOM’s faculty, staff, and systems.
Support for ULSOM during Raise Some L enables numerous direct impacts for our learners, including scholarships based on academic merit, MD/PhD programs, rural county residency status and/or underrepresentation in medicine. Additionally, wellness programs and hands-on experiential learning opportunities are facilitated through initiatives such as counseling services and the LEAD Peer Tutoring Program.
As we strive to enhance learner success, we are committed to expanding opportunities within our specialized medical departments, like surgery, pediatrics, and internal medicine. Maintaining excellence in medical education requires us to stay at the forefront of both standard practices and innovative medical teachings.
Furthermore, ULSOM places great emphasis on the growth and support of its faculty and staff, recognizing that their development enhances our learner outcomes. By investing in their professional growth, we foster a collaborative environment that prepares the next generation of healthcare leaders to advocate effectively for their patients.
The cutting-edge research conducted at ULSOM creates an academic medical hotspot where students are directly involved with the latest advancements in medicine. Life-saving research in areas including cancer, cardiovascular disease, neuroscience, and more allows learners to work with faculty to tackle even the most prominent medical challenges in today’s world.
ULSOM also prides itself on its role as a community partner, providing learners with opportunities to engage in community events and assisting in emergency response efforts. Initiatives led by the Dean’s office connect learners with the community, enhancing medical education while addressing healthcare disparities.
“As we look ahead to the future of the School of Medicine, learner success remains our top priority,” said Jeffrey Bumpous, MD, dean of the UofL School of Medicine. “This year during Raise Some L, I urge you to pledge your support to the University of Louisville School of Medicine to help us create opportunities for learner success as we shape the future of health care, right here in Louisville.”
Raise Some L offers supporters a chance to make a meaningful impact on medical education and the development of future physicians at various stages of their careers. ULSOM appreciates your support in our mission and encourages you to consider making a gift to the School of Medicine.
Nurturing minds of students and trainees at ULSOM
Navigating the demanding path of medical school, residency, and fellowship requires not only academic achievement but also a strong focus on mental health and overall wellbeing. With a healthy mind, healthy body, and healthy soul, future physicians at the University of Louisville School of Medicine (ULSOM) are able to channel increased focus, creativity, and resilience.
Medical training is notoriously challenging, and ULSOM places a high priority on the mental health and wellbeing of its learners.
“The most important thing we do at the School of Medicine to nurture wellbeing and mental health is to prioritize it,” said Matthew Adamkin, M.D., assistant dean for Medical Student Affairs and associate professor, department of Neurological Surgery. “We say that an ounce of prevention is worth a pound of cure. By encouraging learners to develop healthy habits early on, we help them manage the pressures they will inevitably face throughout their training."
Fatigue and burnout are common among medical students and trainees, driven by factors such as high stress levels, sleep deprivation, limited personal time, and the emotional demands of the profession. While support from peers and mentors is invaluable, ULSOM has also established a range of resources to promote wellness.
“We understand that supporting the wellbeing and mental health of our students and trainees is essential to their success as future physicians,” said Jeffrey Bumpous, M.D., dean of the School of Medicine. “By prioritizing mental health from day one, we are not only shaping skilled doctors but also fostering compassionate, resilient individuals who will thrive both personally and professionally throughout their careers.”
The UofL School of Medicine offers students regular wellbeing events, skill-building workshops, and support systems. Social events throughout each semester foster connection, while lunch sessions introduce wellness techniques, like flash-napping and mindfulness. Students have access to the HSC fitness center and counseling services are available for all students.
Trainees in residency and fellowship programs can access the HSC fitness center and benefit from wellness initiatives offered by both the Graduate Medical Education (GME) office and affiliated hospitals. These programs focus on enhancing the mental and physical health of residents and fellows. When extra support is necessary, ULSOM trainees have access to counseling services through the university employee assistance program and campus health services. Additionally, members of the Greater Louisville Medical Society have access to free counseling services.
“In addition to the numerous resources offered by ULSOM, the Graduate Medical Education office organizes social outings, wellness initiatives, community outreach, organized medicine opportunities, financial support, and more to allow over 800 trainees to embrace their wellbeing and mental health,” shared Murali Ankem, M.D., vice dean for Graduate Medical Education. “Fostering wellbeing and mental health is truly an organization-wide priority.”
In recognition of World Mental Health Day, ULSOM encourages all learners to take time to prioritize their mental health and wellbeing. Prioritizing wellbeing and mental health can look vastly different for each learner, but the School of Medicine recommends four basic principles to being the healthiest version of yourself:
- Prioritize sleep: A consistent sleep routine with quality rest boosts cognitive function, mood, and physical health.
- Eat well: Maintain a balanced diet with healthy, nutrient-dense meals.
- Stay active: Engage in regular physical activity to boost mental clarity.
- Manage stress: Implement stress management strategies such as mindfulness and meditation.
By prioritizing wellbeing, ULSOM aims to create a foundation for lifelong learning and personal growth. As learners feel empowered to navigate challenges both inside and outside of the classroom, they are better equipped to absorb information, think critically, and engage fully with the material in front of them.
Class of 2027 Family Day offers an inside look at life of a medical student
The University of Louisville School of Medicine was buzzing with spouses, siblings, parents, and friends at the Class of 2027 Family Day on Friday, October 4th. Gathered in the ULSOM Instructional Building, family members were given the unique opportunity to explore the world of medical education through a series of engaging, hands-on activities led by faculty experts.
“Family Day is a meaningful way to bridge the gap between our academic lives and the support systems that keep us going,” said Ragan Howard, class of 2027 Family Day Chair. “It’s incredible to see our family members engaging in the same learning experiences we go through. We are so grateful to the faculty and staff who made the day possible and for giving our loved ones a deeper understanding of what it means to be a medical student at UofL.”
Russell Farmer, M.D., associate professor of surgery and UofL Health colon and rectal surgeon, led the elective “Medical School 101.” In this session, Farmer walked family members through the rigorous journey of medical students, offering insights into the curriculum, daily expectations, and the highly anticipated residency match process that takes place in the fourth year of medical school.
Attendees were invited to put their diagnostic skills to the test in an interactive ‘Crack the Case’ presentation led by Jennifer Brueckner-Collins, PhD., professor of Anatomical Sciences & Neurobiology. Participants worked on their own patient case, exploring symptoms, past medical history, pertinent lab work, and imaging to reach a diagnosis and develop a treatment plan, mirroring the real-world decision-making process that students experience.
In one of the day’s highlights, Steven Ellis, Ph.D, professor of Biochemistry and Molecular Genetics, held one of his renowned Jeopardy! sessions. Medical students and their guests were able to collaborate while showing off their combined knowledge on a range of topics.
As a nod to Morton Kasdan, M.D., a retired plastic surgeon who has devoted his last twenty years to teaching students how to tie sutures, second-year medical students shared this skill with their families. These students, trained by Kasdan at his Sunday Suture Clinics, guided their families through the basics of surgical knot-tying, giving them a hands-on taste of surgical training.
The Paris Simulation Center was open for guests to complete a real-life case-based simulation. The group of guests acted as physicians to diagnose and treat a patient in a real-life hospital setting. The center’s cutting-edge technology allowed participants to engage in life-like medical scenarios, such as airway management, IV access, chest tube insertion, and central line placement, showcasing the advanced training tools that shape the next generation of healthcare professionals.
Family Day attendees also heard from Olivia Mittel, M.D., associate dean for Medical Student Affairs, and Shorye Durrett, M.D., assistant dean for Medical Student Affairs, who offered remarks on the importance of supporting medical students on their challenging, yet rewarding, journeys.
“It is always a privilege to welcome the families and friends of our students for Family Day,” said Mittel, “this event offers a rare opportunity for loved ones to step into the shoes of their medical students to gain a deeper appreciation for the hard work and dedication it takes to become a physician.”
The School of Medicine is proud to host Family Day annually as a way to foster connections between medical students and their families while celebrating the successes of the institution. Thank you to all who attended, and we look forward to
ULSOM thanks Greater Louisville Medical Society for constant partnership and support
The University of Louisville School of Medicine admires the strong support of its partners. One such partner, the Greater Louisville Medical Society (GLMS), reinforces the School of Medicine’s goal of providing students with a seamless transition into their future as a medical professional. Led by their president, Lewis Hargett, MD, GLMS recently held their annual golf scramble where they raised money to provide scholarships to ULSOM students. The whole ULSOM community thanks GLMS for their backing and encourages faculty, staff, and students to get involved with the organization.
ULSOM: What is the mission behind GLMS?
Hargett: The Greater Louisville Medical Society empowers physicians by creating engaging experiences, advancing meaningful advocacy, and building impactful relationships in the community.
ULSOM: In what ways can ULSOM students benefit from the services and resources offered by GLMS?
Hargett: With the leadership of our physician members, GLMS advocates at a local and state level for all its physicians – that means everyone from aspiring physicians (medical students) to our retired physicians. In addition to advocacy, we host various events throughout the year; one is specifically for M1 and M2 students called Specialty Speed Networking. This award-winning event is like “speed dating” but for medical specialties. Several practicing physicians come out for an evening to share their insights with medical students to help them choose the right specialty for them (specialties are chosen based on M1 and M2 preferences). Another event and opportunity for our M3 and M4 students is the opportunity to apply for a scholarship through our GLMS Foundation Doctor’s Cup Golf Scramble. As of this year, we have awarded a total of 88 students with scholarships. We also provide four free confidential counseling sessions with a psychologist for all our members, to help prevent burnout.
ULSOM: How does GLMS support ULSOM faculty and staff?
Hargett: We sponsor the white coats and professional head shots for incoming medical students at the White Coat Ceremony. In addition to the items mentioned above, GLMS and the GLMS Foundation host various events throughout the year that provide educational and networking opportunities. We also offer a means to give back and invest in the health and well-being of our community by facilitating healthy, organic food giveaways, medical screenings, and resources to those in need in the Greater Louisville area.
ULSOM: What can medical students do to support the mission of GLMS?
Hargett: Get involved, come to an event, write for Louisville Medicine, and let us know you are interested in getting more involved by emails info@glms.org.
ULSOM: How can ULSOM students, staff, and faculty get involved with GLMS?
Hargett: There are several ways students, staff, and faculty can get involved with GLMS.
- Advocacy: Students and faculty with a MD or DO are able to get involved with our Policy & Advocacy Team and work alongside physicians to help with a variety of legislative issues. This team develops resolutions for the KMA Annual Meeting. We will host our Legislative Reception early in 2025 where we invite legislators and Metro Council members to a cocktail reception with our members to have informal discussions about pressing issues. There is also Physicians’ Day at the Capitol where physicians and medical students from across the state go to Frankfort to meet with legislators face-to-face to further discuss those issues in a more formal setting.
- Louisville Medicine: GLMS members are invited to write in our monthly magazine, which is available online and in print and is mailed to physician’s homes (there are also copies in the homerooms on campus). We have a theme each month, but we also have a “non-theme section” in each issue, so we encourage and welcome people to write on any topic at any time. We also have an annual essay contest with cash prize that will kick off in January and winning and honorable mention essays will be published in Louisville Medicine.
- The GLMS Foundation: Volunteer with The GLMS Foundation, which is the charitable arm of GLMS and does some incredible work. While they are constantly doing things throughout the year to help better the health and wellness of physicians and our community, they host two major events throughout the year, the next upcoming is our Doctor’s Cup golf tournament. This raises money for medical student scholarships, and this year, we gave out $12,500 to ten ULSOM students (total of $125,000 scholarships awarded this year)! The Foundation also hosts the Doctors’ Ball, which is both a fundraiser and award ceremony for physicians from all hospital systems and private practices. In addition, we are also always looking for volunteers to help at one of our community events throughout the year.
It is evident that Dr. Hargett and the rest of the team at the Greater Louisville Medical Society are dedicated to creating pathways for excellence in the medical community. The School of Medicine thanks GLMS for their unwavering partnership and constant support of our students, faculty, and staff.
ULSOM recognizes Women in Medicine month with esteemed new faculty member
In recognition of Women in Medicine Month, the University of Louisville School of Medicine (ULSOM) proudly honors the many women who have left their mark on not only ULSOM, but the field of medicine entirely. One such woman is Rebecca Morales, M.D., who recently joined the department of Medicine’s division of Nephrology and Hypertension as an assistant professor.
Inspired by its diverse array of opportunities ranging from clinical practice to community outreach, Morales joined ULSOM for the unique chance to both excel at her passion and explore new ways to improve the quality of care for her patients. “I immediately felt encouraged to pursue all of my goals for setting up an impactful practice here,” said Morales. Since joining, she has already benefitted from strong encouragement from faculty and staff as well as concrete resources to realize her goals with the School of Medicine.
Morales is particularly focused on establishing a strong nephrology clinic for young adults transitioning from pediatric to adult care. “My goals are for this model to serve our population and become a paradigm for transitional care moving forward,” said Morales. “While I enjoy physiology and love the constant learning inherent to our field, there is nothing more motivating than having a truly meaningful impact for our patients. It is a privilege to care from them through triumphs and challenges alike.”
Beyond her clinical work, Morales is dedicated to teaching and mentoring students and residents, aiming to inspire the next generation of nephrologists. “It’s important to me that students see the breadth of opportunities in nephrology and feel empowered to pursue them,” she said.
Women in Medicine Month celebrates trailblazers like Morales, who exemplify that it’s possible to excel as a physician and indelibly impact the field, but that it isn’t necessary to follow a “typical” career trajectory to do so. Morales reminds women in medicine that it is essential to seek out both exciting opportunities and critical support systems to address competing priorities in a physician’s life. “Be open to change and new opportunities that more closely align with your values, priorities, and long-term goals,” she advises.
ULSOM is proud to promote inclusivity for faculty, staff, and learners, ensuring a welcoming environment where everyone in medicine can thrive. One way the school supports new faculty like Morales is through the annual New Faculty Workshop. This year is the eighth annual year hosting the workshop, which will take place Friday, September 27th in Kornhauser Auditorium. New faculty hired within the last year are invited to attend, with presentations including SOM UME Curriculum and Graduate Programs, Teaching with Technology, Safety & Personal Well-being on the HSC, DEI and Community Engagement, Resources Available through Kornhauser Library, and more. Breakout sessions will cover topics like research support, self-directed learning, and Graduate Medical Education.
Those unable to attend will receive workshop materials afterward to ensure they have access to the information shared.
“Our new faculty welcome workshop is an important event that ensures all incoming faculty members feel welcomed and supported,” said Michelle Stevenson, M.D., vice dean of Faculty Affairs. “The workshop provides valuable resources and insights to help faculty members navigate their roles across all components of the academic mission in an inclusive environment. It also offers opportunities for networking with HSC leaders and other new faculty across departments. By creating a space for collaboration and community-building, we are laying the foundation for a culture that thrives on inclusivity and innovation, which ultimately benefits our students, patients, and the broader community.”
Dr. Morales, along with countless other women in medicine, continues to leave an undeniable mark on the ULSOM and beyond. With deep appreciation for their contributions, the ULSOM extends heartfelt thanks to Dr. Morales and all the women making strides in the medical field. Happy Women in Medicine Month!
2024 Kentuckiana Heart Walk: Step by Step, Heart by Heart
The University of Louisville and the UofL School of Medicine, in partnership with UofL Health and the American Heart Association, participated in the annual Kentuckiana Heart Walk on Saturday, September 21 at Waterfront Park. This year’s event saw a record-breaking turnout with 34 teams, 420 walkers, and over $40,000 raised – more than doubling last year’s impact. The funds received by the American Heart Association work to provide CPR trainings and support research, medical breakthroughs, and equitable heart health.
Vendors, giveaways and free blood pressure screenings were offered to the crowd in appreciation of their continuous contributions to the Kentuckiana Heart Walk and walkers were able to enjoy a short loop around Waterfront Park while walking in support of friends, family members, loved ones, or even themselves. UofL and UofL Health walkers sported matching t-shirts to show their support of the full range of heart health initiatives across the organizations.
“I am deeply humbled by the impact our students, staff, trainees, faculty, and partners in health care have chosen to make,” said Jeffrey Bumpous, executive vice president for health affairs and dean of the School of Medicine, “Giving both their time and money to this cause further proves the systemwide dedication to improving the future of health care, one step at a time.”
This year, the American Heart Association celebrates 100 years of making a profound impact on heart health across not only the United States, but the whole world. With a centennial of important work and groundbreaking research behind them, the University of Louisville School of Medicine is proud to be the partner of an organization that is paving the way for heart health.
"I am incredibly proud to see the University of Louisville come together for such a vital cause," said Douglas Craddock, vice president of Community Engagement. "Our partnership with the American Heart Association grows stronger each year, and the success of events like the Kentuckiana Heart Walk highlights our shared commitment to advancing health and wellness in the Louisville community."
The walk’s success reflects the dedication of the UofL community and its commitment to improving heart health. The ULSOM warmly extends gratitude to each participant for their contribution to the 2024 Kentuckiana Heart Walk. We look forward to walking with you next year!
UofL Trager Institute Optimal Aging Clinic urges age-friendly communities in recognition of Healthy Aging Month
This year in recognition of Healthy Aging Month, the University of Louisville School of Medicine celebrates the impactful work being done by the UofL Trager Institute/Republic Bank Foundation Optimal Aging Clinic to promote and advance healthy aging through both clinical and research initiatives. Older adults are one of the fastest-growing groups in the United States, yet Kentucky ranks in the lowest tier of all states on social and economic factors, health outcomes, health behaviors, social support and engagement, and clinical care for adults over the age of 65. The UofL Trager Institute Optimal Aging Clinic is dedicated to transforming the outlook for older adults in Kentucky and across the nation.
“The UofL Trager Institute Optimal Aging Clinic is committed to transforming perceptions of aging by advocating for a positive, proactive approach that encompasses all aspects of a person’s well-being—physical, mental, and emotional,” said Anna Faul, PhD, executive director. “We believe that aging should be celebrated as a time of growth, potential, and continued contribution to society, rather than merely a period of decline.”
The institute is committed to creating age- and dementia-friendly environments that support the well-being of all individuals, regardless of background or cognitive abilities. By promoting inclusivity and addressing healthcare disparities, the Optimal Aging Clinic provides culturally competent, interdisciplinary care—including primary care, behavioral care, lifestyle medicine, and community programs—tailored to meet the diverse needs of older adults. Prioritizing diversity, equity, and inclusion, the Optimal Aging Clinic ensures that everyone can age with dignity and respect.
Through comprehensive workforce development programs, the institute trains health care workers across Kentucky in the development of a broad range of skills that focus on providing respectful, individualized care, allowing individuals to flourish as they age. This training spans a wide range of disciplines, preparing providers to meet the diverse needs of older adults.
In collaboration with interdisciplinary researchers, practitioners, and students from the University of Louisville and collaborating universities, the institute addresses the emerging needs of older adults and their families through innovative research and evaluation. Key areas of focus include interdisciplinary care coordination, brain health models of care, geriatric medicine, behavioral health and the signature FlourishCare Model and FlourishCare Index. Additionally, integrated primary care and behavioral health, lifestyle medicine interventions such as tai chi, yoga, nutrition classes, and art classes, as well as the Virtual Friendly Visitors program used to combat social isolation are also evaluated for their respective impact on the older adults served. The institute also studies the best, innovative interprofessional education models to advance training in these areas and conducts clinical trials with older adults.
The Trager Institute provides interprofessional education through a variety of programs accessible to learners at any stage in their health care education and career, including:
- Interprofessional Case Management Experience, online modules and virtual case management experience
- Project ECHO, virtual monthly sessions
- Clinical Retreat for Interdisciplinary Training, single day immersive experience
- Optimal Aging Conference, multi-day event
- Online Learning Management System
As the Trager Institute challenges conventional stereotypes about aging, it is essential to shift the narrative so that individuals can embrace this stage of life as one filled with opportunities for new experiences, learning, and personal growth.
“Healthy Aging Month is a call to action for communities, health care providers, and policymakers to support environments and policies that enable older adults to thrive,” said Jeffrey Bumpous, MD, executive vice president of health affairs and dean of the School of Medicine at UofL. “The ultimate goal is to inspire a cultural shift that values and supports older adults in living their lives to the fullest, no matter their age.”
As we reflect on Healthy Aging Month and the work being done by the UofL Trager Institute Optimal Aging Clinic, let it serve as a reminder to focus on your physical well-being, cognitive health and emotional resilience.
Fourth year of Future Healers program led by ULSOM students commences with white coat ceremony
Excitement stirred amongst the latest group of Future Healers as they waited to receive their white coats in a replicated white coat ceremony. With scrubs, a medical supplies kit, and medical textbooks in hand, the participants in their new white coats were more than ready to begin the fourth year of the program.
Future Healers began as a collaboration between students from the University of Louisville School of Medicine and the UofL Health – Trauma Institute. Designed to address the impact of gun violence on Jefferson County, the Future Healers program bridges Louisville’s health care organizations and local youth that have been impacted by gun violence.
While creating a safe space for local youth to navigate their emotional trauma, the program introduces the children to the field of medicine through free, interactive lessons. Topics covered in the program include nutrition, mental health, anatomy, first aid, and more. Mentorships and participation in field trips, medical school tours, hospital tours, and community events are popular additions to the program.
With each year of the program, Future Healers has been able to offer new and exciting opportunities to promote growth and learning. Since its initiation in 2021, the Future Healers program has grown exponentially, even providing participants with free books and medical supplies to take back to their homes, in addition to offering authentic hands-on models and dissections.
More than 200 children have experienced the power of the monthly educational curriculum, mentorship opportunities, and local events of Future Healers. Children between the ages of four and 13 are invited to participate in monthly sessions held at the Galt House or UofL Health – UofL Hospital. Starting with a wellness portion and transitioning into medical stations, students are introduced to many unique, impactful topics. The fan favorite, of course, has been the pig eye dissection station! Simplified monthly sessions are held for the preschoolers at the Chestnut Street YMCA. Mentorship opportunities are available for children outside of the specified age range.
The participants have had an overwhelming response to the experience. Most of the participants felt they were capable of becoming health care providers, and more than half shared they planned to enter the medical/STEM field when they grow up.
“We hope that even if they do not wish to pursue a career in medicine, that this environment can serve as a place to explore their interest, find positive role models, and discover that they are deserving of a strong future,” said Baylee Polzin, former Future Healers Co-Executive Director and current ULSOM student.
The UofL Health – Trauma Institute, including Keith Miller, M.D. and Christopher Jones, M.D. work with community partner Christopher 2X and his organization 2X Game Changers to support the mission created by the ULSOM students. ULSOM students are the primary creators of the medical curriculum that is presented to Future Healers participants, in addition to fundraising and running social media sites. Approximately 200 medical students volunteer with Future Healers, allowing the monthly programming to be almost exclusively run by students.
“The medical students have truly made an immense impact on children affected by gun violence as they pour hours into the program, while also pursuing their medical degrees. Their dedication to making a difference is nothing short of remarkable, and all of us in the UofL Health – Trauma Institute are truly honored to contribute to their mission,” said Dr. Miller.
Volunteers from medical professions, including medical and dental students, nurses, physicians, or other health care professionals are welcomed, as well as undergraduate students at the University of Louisville. All volunteers must have a background check and may require specific training. For more information, email futurehealersky@gmail.com.
Interested families can get involved with the Future Healers organization by reaching out to stefanie.upton@uoflhealth.org.
ULSOM Honors the Legacy of Alumnus Jim Heins
The University of Louisville School of Medicine mourns the loss of alumnus James (Jim) Heins, who passed March 15, 2024. Following his Celebration of Life on July 13, ULSOM took some time to reflect on Jim’s legacy at the University of Louisville.
After an undergraduate career in basketball at the University of Louisville that ended with a 1956 National (Invitation) Tournament championship win, Jim Heins was offered a full scholarship to the School of Medicine. Jim finished first in his class and went on to complete training in Internal Medicine at Barnes Hospital in St. Louis, Missouri, where he practiced and taught for the remainder of his career. He did the compulsory two years at NIH and earned a unique tenured professorship in teaching at Washington University Medical School.
Hiram C. Polk Jr., M.D., who completed residency with Jim Heins at Barnes Hospital, remembers him as not just a colleague, but a friend: “Jim was a remarkable example of the lasting impression that the University of Louisville School of Medicine leaves on its alumni. The years Jim spent practicing and teaching medicine barely brush the surface of the impact he had on the medical field. He is greatly missed.” Jim’s wife, Joan McDonogh Heins, is a proud alumna of Sacred Heart Academy.
The University of Louisville School of Medicine fondly remembers Jim Heins and the many years he spent as a physician and professor of internal medicine.
Gibbs Foundation invests $3 million with UofL Health – Brown Cancer Center
The University of Louisville, UofL Health – Brown Cancer Center and the Gibbs Foundation will continue their partnership in finding a cure for cancer through a new $3-million investment. Thanks to the success of their prior funding, the Gibbs Foundation has committed $1.5 million to continue support for Tumor Infiltrating Lymphocytes cell therapy (TILs) which led to the therapy’s FDA approval in Feb. 2024. In addition, the Gibbs Foundation has committed $1.5 million over three years to create the Gibbs Pancreatic Cancer Research Center which will support innovative research to reduce deaths caused by this incurable cancer.
Support of TILs cell therapy
Half of this incredible investment in the Brown Cancer Center, $1.5 million, supports the TILs program by providing funding for research staff, supplies and faculty time dedicated to clinical trials. The goal is to increase capacity and access for participants in clinical trials for TILs and other immunotherapies.
The Brown Cancer Center is a lead enrolling center in TILs trials and has had patients travel to Louisville from all over the United States. The success of the program is directly related to the Gibbs Foundation initial investment of $1.5 million in 2022.
This philanthropic investment follows FDA approval of the cell product AMTAGVI™ (lifileucel), developed by Iovance Biotherapeutics for the treatment of melanoma patients. The Brown Cancer Center participated in these clinical trials leading to this FDA approval and is one of the first authorized treatment centers.
Although the initial FDA approval is specific to metastatic melanoma, the expansion of this cellular therapy to other cancers is being tested at Brown Cancer Center and elsewhere with a goal to obtain FDA approval in several solid tumor types in the future. Read more on the FDA approval in the UofL Health press release.
Creation of Gibbs Pancreatic Cancer Research Program
Through $1.5 million over three years, the Gibbs Pancreatic Cancer Research Program will be created at the University of Louisville to support efforts in testing novel therapeutic agents for the treatment of pancreatic cancer. Five $50,000 pilot grants will be awarded to researchers each year for the development of novel therapeutics to treat pancreatic cancer and increase clinical trials dedicated to treating pancreatic cancer. This center will also provide funding for trial research staff and faculty time dedicated to these projects.
Executive Director of the Gibbs Foundation Hannah Roquet said, “The Gibbs Foundation is thrilled to be continuing our partnership with the Brown Cancer Center and the fight against cancer. Based on the positive outcomes of so many patients who have been through the TILs program, it is a battle we are winning. The creation of the Gibbs Pancreatic Cancer Research Program is especially meaningful as it continues the legacy of our founder, George Gibbs, who fought his own battle valiantly, and provides the opportunity for groundbreaking research in a cancer that has taken the lives of many too quickly and without warning. We are looking forward to the future of this very special program.”
The Gibbs Foundation, Inc. was established in 2014 by George Gibbs of Louisville who died in 2022 of pancreatic cancer at age 87. The Gibbs Foundation previously supported health research at UofL through gifts of more than $2.5 million to create and expand the Gibbs Lung Research Program.
“The Brown Cancer Center has one goal – to end cancer,” said Jason Chesney, chief administrative officer and director of the Brown Cancer Center, who also serves as chief of the Division of Medical Oncology and Hematology at the UofL School of Medicine. “As more cancer centers across the country begin to implement TILs programs, we will be saving more lives. Through the philanthropy of the Gibbs Foundation, we continue to be one step closer to achieving this goal. Their dedication to finding a cure and increasing access to novel therapeutics is astounding.”
More information on TILs therapy and UofL Health – Brown Cancer Center is available at UofLHealth.org/BCC.
UofL Researcher Studies Link Between Cancer and Alzheimer’s Disease
Cancer and Alzheimer’s Disease are not generally thought to be related, but University of Louisville researcher Levi Beverly, Ph.D. has noted that there are more similarities than we may have previously thought.
While studying a gene family called Ubiquilins, Beverly noticed that while the gene family is lost in human lung cancers, Ubiquilin2 is mutated and is a driving gene in familial early-onset ALS. With this fact in mind, Beverly found that the Ubiquilin gene family was primarily studied in relation to neurodegenerative disorders, including Alzheimer’s Disease and ALS. Hence, Beverly decided to delve into this inverse relationship between cancer and neurodegenerative disorders.
So, does this indicate that cancer survivors are less likely to develop neurodegenerative disorders? Current research suggests that the treatment of cancer patients with chemotherapies may decrease the risk of developing Alzheimer’s Disease later in life. Many studies have used cancer drugs in mouse models of Alzheimer’s Disease, with some delaying progression of the disease. However, much more research must be done before any conclusion can be drawn as to why cancer survivors may be less likely to have Alzheimer’s Disease.
As for a drug that could treat both conditions, Beverly explains that this may be possible: “While a drug to treat both cancer and neurodegenerative disorders does not currently exist, it could be a possibility. Cancer is a disease of too much growth and cell survival, whereas neurodegeneration is too much cell death. Such a drug would need to restore Ubiquilin function in order to effectively treat the two conditions, which are at two opposite ends of the spectrum,” Beverly explains.
Currently, there are not many scientists researching the similarities between the two diseases. This is due, in part, to the fact that it is not common to be an expert in both cancer and neurodegenerative disorders. Beverly, for instance, has worked in cancer biology for 25 years. Only recently has he started to research neurodegenerative disorders. This, Beverly explains, is why collaborations are so important.
“Collaborations between experts in both areas are the key to bridging the gap between the two very different conditions. However, there also arises a difficulty in receiving funding. Because cancer and neurodegeneration are very different, funding for researching this inverse relationship can be very hard to come by,” Beverly explains, “Moving forward, despite these obstacles, it is my hope that scientists from both fields keep their eyes open and don’t discount the similarities of these two diseases.”
In honor of Alzheimer’s Awareness Month, the ULSOM commends Dr. Levi Beverly and his dedication to researching the inverse relationship between cancer and neurodegeneration. We remain excited to learn more about Beverly’s research and the future of these two conditions.