Centers of Biomedical Research Excellence (COBRE) Grant

The University of Louisville Center for Biomedical Research (COBRE), in Functional Microbiomics, Inflammation and Pathogenicity is a multidisciplinary research center dedicated to finding new ways to fight potentially devastating diseases while creating the next generation of innovation leaders. 

In the past few decades, the fields of inflammation and pathogenicity have undergone a renaissance, driven in part by technological advances, which have shaped our understanding of the human microbiome and its role in fundamental aspects of human health and disease. 

Advances in our understanding of the microbiome, along with a realization that inflammatory processes are at the core of a number of common diseases, necessitates a cross-disciplinary perspective that accommodates the host-microbe interface. 

The UofL COBRE is conducting an integrated set of complementary projects to make novel connections between inflammatory processes and bacterial pathogenicity, and establish the basis for the development of novel therapeutics and delivery methods. 

We are creating a multidisciplinary program in research, education, mentoring and career development that will facilitate and accelerate the transition of junior faculty to independent extramural funded status.