M&I Faculty Awarded Multiple NIH/NIAID Grants in 2017

M&I Associate Professor Matthew Lawrenz was recently awarded a National Institute of Health R21 grant entitled "Zinc Acquisition in Yersinia pestis".  The major goal of this project is to define the contribution of the yersiniabactin synthase-dependent zinc acquisition system on the virulence of Yersinia pestis.  This NIH funded project is budgeted from 11/24/2017 - 10/31/2019 for $437,080.


M&I Professor Dr. Esma Yolcu recently awarded a National Institute of Health SSRT grant to study “SA-FasL-engineered human islets as a novel product for the treatment of type 1 diabetes."  The major goal of this phase I STTR application is to develop SA-FasL-engineered human islets as a novel immune privileged product for the treatment of type 1 diabetes (T1D).  This NIH funded project is budgeted from 07/01/2017 – 03/30/2018 for $224,529.00.

 

M&I Professors Drs. Thomas Mitchell and Carolyn Casella were recently awarded a National Institute of Health R01 grant to study “Mechanisms of successful vaccine adjuvants." This NIH funded project is budgeted from 06/26/2017 – 05/31/2022 for $1,925,000.

     Casella

 

Drs. Haval Shirwan and Esma Yolcu have been awarded a multiple PI NIH/NIAID UO1 grant with Andres Garcia from Georgia Institute of Technology. The grant is entitled “Targeted delivery of immunomodulatory biologics for induction of immune privilege to allogeneic pancreatic islet grafts”.  The major focus of this project is to develop immunomodulatory biomaterials for induction of tolerance to allogeneic islets as a cure for type 1 diabetes.  The award amount of $1,954,270 is budgeted for 06/20/20176 – 05/31/2022

      

 

M&I Professor and Vice Chair, Haribabu Bodduluri, PhD was awarded a grant titled ‘Innate immune mechanisms regulating silicosis”. This NIH/NIAID funded project is budgeted from 6/6/2017 - 5/30/2019 for $423,500. This research is important to explore the mechanisms of their recent work on silicosis and lung cancer; https://www.sciencedaily.com/releases/2015/04/150429084837.htm

Hari Bodduluri

 

M&I Associate Professors Drs. Jon Warawa and Matt Lawrenz were recently awarded an NIH/ NIAID grant contract to study “Therapeutics Testing In a Murine Model of Multiple Drug Resistant (MDR) Pseudomonas Aeruginosa Lung Infection.” This NIH/ NIAID funded project is budgeted from 03/2017 – 11/2018 for $729,174.

Jonathan Warawa     Matthew Lawrenz

 

M&I Assistant Professor Dr. Krishna Jala was recently awarded a National Cancer Institute of National Institute of Health R21 grant to study “PQ-10:  Microbial metabolite, Urolithin A is a potent immunomodulator and chemosensitizing adjuvant in treating color cancer.” This NIH funded project is budgeted from 04/12/2017 – 03/31/2019 for $368,445.

 

M&I Associate Professor Dr. Jon Warawa was recently awarded an NIH/ NIAID grant contract to study “HHSN272201000033I/HHSN2720005 / Task A91- Mod #1.” This NIH/ NIAID funded project is budgeted from 03/21/2017 – 05/25/2018 for $508,703.

 

M&I Professor Dr. Nathan Schmidt was recently awarded an NIH/ NIAID grant contract to study “Role of gut microbiota in shaping severity of malaria.” This NIH/ NIAID funded project is budgeted from 01/11/2017 – 12/31/2021 for $2.6M.  http://uoflnews.com/post/uofltoday/uofl-researcher-awarded-2-6m-nih-grant-to-study-links-between-gut-microbiota-and-disease/