Education and Training

• Ph.D.: Washington State University, Environmental Science

Research Interests

Dr. Holm is an Associate Professor in the Christina Lee Brown Envirome Institute. She specializes in water and sanitation technologies, environmental health to improve the well-being of the most vulnerable population groups and the role of fecal waste streams in public health surveillance.

Featured Publications

• Han D, Linares P, Holm RH, Chandran K, Smith T. Wastewater threshold as an indicator of COVID-19 cases in correctional facilities for public health response: A modeling study. Water Res. 2024 Aug 15;260:121934. doi: 10.1016/j.watres.2024.121934. Epub 2024 Jun 12. PMID: 38908309.
• Jin A, DuPré N, Holm R, Smith T, Kavalukas S. Environmental Levels of Volatile Organic Compounds, Race, and Socioeconomic Markers Correlate with Areas of High Colorectal Cancer Incidence. J Racial Ethn Health Disparities. 2024 May 16. doi: 10.1007/s40615-024-02030-z. Epub ahead of print. PMID: 38755478.
• Hodge B, Holm RH. Where Does Wastewater-Based Epidemiology Fall in Medical Student Education? J Med Educ Curric Dev. 2024 May 2;11:23821205241252069. doi: 10.1177/23821205241252069. PMID: 38706937; PMCID: PMC11067427.
• Chigwechokha P, Nyirenda RL, Dalitsani D, Namaumbo RL, Kazembe Y, Smith T, Holm RH. Vibrio cholerae and Salmonella Typhi culture-based wastewater or non-sewered sanitation surveillance in a resource-limited region. J Expo Sci Environ Epidemiol. 2024 May;34(3):432-439. doi: 10.1038/s41370-023-00632-z. Epub 2024 Jan 4. PMID: 38177335.
• Holm RH, Rempala GA, Choi B, Brick JM, Amraotkar AR, Keith RJ, Rouchka EC, Chariker JH, Palmer KE, Smith T, Bhatnagar A. Dynamic SARS-CoV-2 surveillance model combining seroprevalence and wastewater concentrations for post-vaccine disease burden estimates. Commun Med (Lond). 2024 Apr 9;4(1):70. doi: 10.1038/s43856-024-00494-y. PMID: 38594350; PMCID: PMC11004132.
• Anderson LB, Ness HD, Holm RH, Smith T. Wastewater-Informed Digital Advertising as a COVID-19 Geotargeted Neighborhood Intervention: Jefferson County, Kentucky, 2021-2022. Am J Public Health. 2024 Jan;114(1):34-37. doi: 10.2105/AJPH.2023.307439. Epub 2023 Oct 19. PMID: 37856730; PMCID: PMC10726935.
• Klaassen F, Holm RH, Smith T, Cohen T, Bhatnagar A, Menzies NA. Predictive power of wastewater for nowcasting infectious disease transmission: A retrospective case study of five sewershed areas in Louisville, Kentucky. Environ Res. 2024 Jan 1;240(Pt 2):117395. doi: 10.1016/j.envres.2023.117395. Epub 2023 Oct 12. PMID: 37838198; PMCID: PMC10863376.
• Marin-Ramirez A, Mahoney T, Smith T, Holm RH. Predicting wastewater treatment plant influent in mixed, separate, and combined sewers using nearby surface water discharge for better wastewater-based epidemiology sampling design. Sci Total Environ. 2024 Jan 1;906:167375. doi: 10.1016/j.scitotenv.2023.167375. Epub 2023 Sep 27. PMID: 37774884.
• Sokoloski KJ, Holm RH, Smith M, Ford EE, Rouchka EC, Smith T. What is the functional reach of wastewater surveillance for respiratory viruses, pathogenic viruses of concern, and bacterial antibiotic resistance genes of interest? Hum Genomics. 2023 Dec 18;17(1):114. doi: 10.1186/s40246-023-00563-8. PMID: 38105239; PMCID: PMC10726489.
• Holm RH, Nyirenda R, Smith T, Chigwechokha P. Addressing the challenges of establishing quality wastewater or non-sewered sanitation-based surveillance, including laboratory and epidemiological considerations, in Malawi. BMJ Glob Health. 2023 Nov;8(11):e013307. doi: 10.1136/bmjgh-2023-013307. PMID: 37918872; PMCID: PMC10626866.