Graduates of the Department of Pharmacology and Toxicology

#GraduateDegreeYearMentor (s)Dissertation/Thesis Title (electronic versions)
402

Disha Nagesh Moholkar

M.S.2024Ramesh Gupta, Ph.D.

Exosomal cannabidiol:  A promising candidate for targeted oral delivery against breast cancer

401

Katarina L. Mayer

M.S.2024Nobuyuki Matoba, Ph.D.

Investigation of avaren-Fc's therapeutic potential against ovarian cancer

400

Wendy Kittle

M.S.2024Nobuyuki Matoba, Ph.D.

EPICERTIN's preclinical path to mucosal healing in ulcerative colitis 

399

Kennedy M. Walls

Ph.D.2023David W. Hein, Ph.D. & Kyung U. Hong, Ph.D.

Investigation of heterocyclic amines and N-acetyltransferase 2 genetic polymorphism in the dysregulation of hepatic energy homeostasis:  A gene-environment approach

398

Sarah H. Shrader

Ph.D.2023Zhao-Hui (Joe) Song, Ph.D. & Gregory N. Barnes, M.D., Ph.D.Cannabidiol, behavior & the immune system in idiopathic autism spectrum disorder
397

Tyler C. Gripshover

Ph.D.2023Matthew C. Cave, M.D.The impact of environmental pollutants on alcohol-associated liver disease pathogenesis
396

Caitlin C. Wilkerson

M.S.2023Walter H. (Bert) Watson, Ph.D.

Ethanol dysregulates Sirt1-mediated lipogenic signaling pathways through α4*-nicotinic acetylcholine receptors in hepatocytes

395

Samuel T. Vielee

M.S.2023Johnny Wise Jr., Ph.D. & John P. Wise, Sr., Ph.D. 

Using a toxic aging coin to assess hexavalent chromium-induced neurotoxicity

394

Daniel C. Gomes

M.S.2023Timothy O'Toole, Ph.D.

Environmental exposures and aging

393

Dakota D. Cathey

M.S.2023Lu Cai, M.D., Ph.D. & Jiapeng Huang, M.D., Ph.D.

Study of the effects of chronic cadmium exposure on the pathogenesis of pulmonary arterial hypertension

392

Raphael Jigo

M.S.2023Geoffrey J. Clark, Ph.D.

Inhibition of RALGDS as a therapeutic approach in NSCLC

391Dana HammouriM.S.2023Tamer M.A. Mohamed, Ph.D.

KDM5B as a potential epigenetic regulator of cardiomyocyte regeneration and cell cycle activation

390Ngozi V. AdieleM.S.2023Matthew C. Cave, M.D.

The effects of environmental pollutants on liver disease: role of the gut-liver axis

389Jeffrey B. WarnerPh.D.2023Irina A. Kirpich, Ph.D.

Soluble epoxide hydrolase inhibition: A novel therapeutic strategy for alcohol-associated liver disease

388Micaela A. ReevesPh.D.2023Nobuyuki Matoba, Ph.D.

EPICERTIN: preclinical development of a novel mucosal healing agent

387Andrew J. OrwickPh.D.2023Leah Siskind, Ph.D. & Levi Beverly, Ph.D.

Lung cancer-kidney crosstalk prevents protection from 5-hydroxytryptamine 1F receptor agonist in repeated low dose cisplatin induced nephrotoxicity

386Sean M. RaphPh.D.2022Matthew A. Nystoriak, Ph.D.  

Voltage gated potassium channel dependent mechanisms of cardiovascular adaptation to chronic exercise

385Nagwa El-BazPh.D.2022Martin G. O'Toole, Ph.D.

The impact of pegylation on cellular uptake and in vivo biodistribution of gold nanoparticle MRI contrast agents 

384Breandon S. TaylorM.S.2022Sanjay Srivastava, Ph.D.

The impact of volatile organic compound exposure on subclinical biomarkers of cardiovascular injury

383Mariam R. HabilPh.D.2022David W. Hein, Ph.D.Investigation of human N-acetyltransferases (NAT1 and NAT2) genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity
382Samantha A. McFallM.S.2022Sanjay Srivastava, Ph.D.

The effect of volatile organic compounds on endothelial function and atherogenesis 

381Kate TarvestadM.S.2022Brian P. Ceresa, Ph.D.
HGF-mediated c-Met signaling in human corneal epithelial cells
380Haiyan LuPh.D.2022John P. Wise, Sr., Ph.D.
Translating particulate hexavalent chromium-induced chromosome instability from human lung cells to experimental animals, human lung tumors, and whale cells
379

Alyssa S. Aebersold

Ph.D.2022Zhao-hui (Joe) Song, Ph.D.

Application of cannabidiol to occular pharmacokinetics and pharmacodynamics

378

Andre D. Richardson

Ph.D.2022Daniel J. Conklin, Ph.D.

Tobacco-derived aldehydes, platelets and thrombogenicity:  Role of transient receptor potential ankyyrin-1

377

Jennifer H. Toyoda

Ph.D.2022John P. Wise, Sr., Ph.D.

Molecular mechanisms of hexavalent chromium-induced centrosome amplification 

376

Hunter A. Miller

Ph.D.2022Hermann B. Frieboes, Ph.D.

A modeling platform to predict cancer survival and therapy outcomes using tumor tissue derived metabolomics data

375

Aaron G. Whitt

Ph.D.2022Chi Li, Ph.D.

The roles of PON2 in mitochondrial physiology, lung tumor cell proliferation, and lung tumorigenesis

374

Mengwei Jiang

Ph.D.2022Wenke Feng, Ph.D.

Extracellular vesicles from Lactobacillus rhamnosus GG protect against alcohol-induced liver injury through suppression of intestinal miR194 and subsequent activation of FXR in mice

373

 Aggie R. Williams

M.S.2022John P. Wise, Sr., Ph.D.

Particulate hexavalent chromium inhibits homologous recombination repair by targeting RAD51 paralogs in human lung fibroblasts

372

Lucy J. Sloan

M.S.2022Zhao-hui (Joe) Song, Ph.D. &  Shigeo Tamiya, Ph.D.

Cannabinoids and retinal fibrotic disorders

371

Angeliki Lykoudi

M.S.2021J. Christopher States, Ph.D.

Assessing the role of arsenic exposure and miRNA-186 in skin tumorigenesis and chromosomal instability

370

Matthew W. Dent

Ph.D.2021Nobuyuki Matoba, Ph.D.

Preclinical development of Avaren-FC:  A novel lectin-FC fusion protein targeting cancer-associated high-mannose glycans

369

Nicholas A. Hoffman

M.S.2021Leah Siskind, Ph.D.

The role of sphingolipids in AKI and the progression to CKD: potential therapeutic targets

368

Idoia Meaza Isusi

M.S.2021John P. Wise, Sr., Ph.D.

Translating particulate Cr(VI)-induced chromosome instability, loss of homologous recombination repair and targeting of RAD51 from human lung fibroblasts to bronchial epithelial cells

367

Sophia M. Sears

Ph.D.2021Leah Siskind, Ph.D. & Levi Beverly, Ph.D.

Characterizing the role of macrophages in cisplatin-induced kidney injury and progression to chronic kidney disease

366

Marc M. Dwenger

Ph.D.2021Matthew A. Nystoriak, Ph.D.  

Pyridine nucleotide redox potential in coronary smooth muscle couples myocardial blood flow to cardiac metabolism

365

Srineil Bodduluri

M.S.2021Shirish Barve, Ph.D.

Histone deacetylases in alcohol associated liver disease

364

George Z. Wei

Ph.D.2021Scott R. Whittemore, Ph.D. & Michal Hetman, M.D., Ph.D.

Oligodendrocyte responses after spinal cord injury

363

Tyler C. Gripshover

M.S.2021Matthew C. Cave, M.D.

Investigating the effects of perfluorooctanoic sulfonate (PFOS) and ethanol on fatty liver disease using a modified NIAAA model

362

Andrew J. Orwick

M.S.2021Leah Siskind, Ph.D. & Levi Beverly, Ph.D.

The role of PGC-1α in repeated low-dose cisplatin-induced kidney injury and the progression to chronic kidney disease

361

Kennedy M. Walls

M.S.2021David W. Hein, Ph.D. & Kyung U. Hong, Ph.D.

Heterocyclic amines and arylamine N-acetyltransferase 2 polymorphism in pathogenesis of insulin resistance

360

Austin M. Krueger

M.S.2021Leah Siskind, Ph.D. & Levi Beverly, Ph.D.

Characterizing the role of Src in NSCLC cell and fibroblast migration on 3D cell-derived matrix

359

Micaela A. Reeves

M.S.2021Nobuyuki Matoba, Ph.D.

Preclinical development of Epicertin, a novel biotherapeutic for the treatment of ulcerative colitis

358

Mohamed A.  Elnagdy

M.S.2021Leila Gobejishvili, Ph.D.

PDE4 inhibition:  A novel therapeutic strategy of liver fibrosis

357

Sean M. Raph

M.S.2021Matthew A. Nystoriak, Ph.D.  

Myocardial blood flow control by oxygen sensing vascular KVβ proteins

356

Christine Kim

Ph.D.2021Brian P. Ceresa, Ph.D.

Assessing the role of arsenic in the EGFR signaling axis

355

Jamie L. Young

Ph.D.2020Lu Cai, M.D., Ph.D.

The effects of whole life, low dose cadmium exposure on high fat diet-induced NAFLD and the role of zinc

354

Jian (Joseph) Jin

Ph.D.2020Matthew C. Cave, M.D.

Effects of polychlorinated biphenyls on nonalcoholic fatty liver disease: Role of the aryl hydrocarbon receptor

353

Jeffrey B. Warner

M.S.2020Irina A. Kirpich, Ph.D.

Soluble expoxide hydrolase inhibition:  A novel therapeutic strategy in alcoholic liver disease

352

Rachel M. Speer

Ph.D.2020John P. Wise, Sr., Ph.D.

Mechanisms of chromate-induced suppression of RAD51: A one environmental health approach

351

Mariam R. Habil

M.S.2020David W. Hein, Ph.D.

N-Acetyltransferase 2 (NAT2) genotype polymorphism in cryopreserved human hepatocytes and Chinese hamster ovary (CHO) cells

350

Desmond R. Harrell Stewart 

Ph.D.2020Geoffrey J. Clark, Ph.D.

A novel role for RASSF1A in the regulation of RAS activation

349

Shuhan (Ellen) Meng

Ph.D.2020Chi Li, Ph.D.

Exosomes from embryonic stem cells as a prophylactic vaccine against lung cancer

348

Jordan B. Lynch

Ph.D.2020Daniel J. Conklin, Ph.D.

Tobacco product-derived aldehydes: Effects on circulating angiogenic cells & implications for cardiovascular disease

347

Fengyuan (Linda) Li

Ph.D.2020Wenke Feng, Ph.D.

Dual role of antimicrobial peptide cathelicidin in alcohol-associated liver disease

346

Lexiao (Monica) Jin

Ph.D.2020Daniel J. Conklin, Ph.D.

The cardiovascular effects of tobacco product-derived aldehydes: Contribution of Transient Receptor Potential Ankyrin-1

345

Yuxuan Zheng

Ph.D.2020Walter H. Watson, Ph.D.

The role of Slc7a11 in controlling extracellular and intracellular redox environments of lung fibroblasts - potential targets for intervention in aging and idiopathic pulmonary fibrosis

344

Yihong (Summer) Li

Ph.D.2020Shao-yu Chen, Ph.D.

Sulphorophane protects against ethanol-induced apoptosis and teratogenesis through epigenetic modulation of anti-apoptotic genes

343

Andre D. Richardson

M.S.2020Daniel J. Conklin, Ph.D.

Tobacco-derived aldehydes: Platelet activation, thrombosis and the role of TRPA1

342

Adrienne Bushau-Sprinkle

Ph.D.2020

Eleanor Lederer, M.D.

Mechanistic insight of the role of NHERF1 in cisplatin-induced acute kidney injury

341

Al Hassan Kyakulaga

Ph.D.2019Ramesh C. Gupta, Ph.D.Therapeutic potential of Withaferin A against non-small cell lung cancer
340Joshua M. RoyalPh.D.2019Nobuyuki Matoba, Ph.D.A recombinant cholera toxin B subunit variant with a endoplasmic retention KDEL motif (CTB-KDEL) exhibits unique colon mucosal healing effects that have therapeutic implications for inflammatory bowel disease
339Kevin M. TyoPh.D.2019Jill Steinbach-Rankins, Ph.D.Electrospun fibers and nanoparticles for the prevention of sexually transmitted infections
338Sarah H. ShraderM.S.2019Zhao-Hui (Joe) Song, Ph.D.Discovery of novel molecular targets for endogenous and phytocannabinoids
337

Sophia M. Sears

M.S.2019

Leah J. Siskind, Ph.D.

Characterizing the roles of neutral ceramidase in cisplatin-induced kidney injury

336

Aditya S. Barve

Ph.D.2019

Levi Beverly, Ph.D.

Characterization of a more clinically relevant human leukemia xenograft model to examine perturbation of MET/SAM metabolism as a novel paradigm for MLL-R leukemia in vivo

335

Douglas J. O. Saforo

Ph.D.2019

Levi Beverly, Ph.D. & Leah J. Siskind, Ph.D.

Characterizing the role of extracellular matrix in non-small cell lung carcinoma metastasis using a 3D microenvironment mimetic in-vitro culture system

 

334

Christine E. Dolin

Ph.D.2019

Gavin E. Arteel, Ph.D. & Michael L. Merchant, Ph.D.

Novel mechanisms and biomarkers in alcohol-induced organ injury

333

Mohamed Y. Mahmoud

Ph.D2019

Jill M. Steinbach-Rankins, Ph.D. & Donald R. Demuth, Ph.D. 

Development of BAR-peptide nanoparticles and electrospun fbers for the prevention and treatment of oral biofilms

332

Matthew W. Dent

M.S.2019Nobuyuki Matoba, Ph.D.

Development of a lectin-FC fusion protein with antiviral and anti-cancer activity 

331

Aaron G. Whitt

M.S.2019Chi Li, Ph.D.

Paraoxonase 2 is critical for non-small cell lung carcinoma proliferation

330

Shanice V. Hudson

Ph.D.2018Gavin E. Arteel, Ph.D. &  Hermann B. Frieboes, Ph.D.

Innate immunity, the extracellular matrix, and liver injury:  mathematical modeling of metastatic potential and tumor development in alcoholic liver disease

329

Fengyuan (Linda) Li

M.S.2018Wenke Feng, Ph.D.

The role of cathelicidin in the regulation of gut microbiota and inflammasome activation in alcoholic liver disease

328Jamie S. RushM.S.2018Brian P. Ceresa, Ph.D.

Epidermal growth factor-like ligands regulate dimer selection

327Liya (Leah) ChenPh.D.2018Juliane I. Beier, Ph.D.

The role of aldehyde dehydrogenase 2 in liver injury caused by vinyl chloride and high-fat diet

326Ashley M. MuddPh.D.2018Ramesh C. Gupta, Ph.D.

Influence of bilberry-derived anthocyanidins on key regulators of colorectal cancer development

325Christine KimM.S.2018Brian P. Ceresa, Ph.D.Assessing the role of arsenite in disrupting the EGFR signaling axis
324Qian (Zoe) LinPh.D.2018Yi Tan, M.D., Ph.D.A novel fibroblast growth factor 1 variant reverses nonalcoholic fatty liver disease in type 2 diabetes
323Harshulkumar M. PanditPh.D.2018Robert C.G. Martin II, M.D., Ph.D.WNT/β-catenin mediated cancer stem cell activation in hepatocellular carcinoma
322Jennifer H. ToyodaM.S.2018John P. Wise, Sr., Ph.D.Particulate hexavalent chromium does not induce centrosome amplification in sperm whale and bowhead whale cells
321Samantha M. CarlislePh.D.2018David W. Hein, Ph.D.Deciphering the role of human arylamine N-acetyltransferase 1 in breast cancer cell metabolism using a systems biology approach
320Hunter A. MillerM.S.2018Hermann B. Frieboes, Ph.D.Evaluation of nanoparticle transport and effect in heterogeneously vascularized tumor tissue
319Nagawa El-BazM.S.2018Martin G. O'Toole, Ph.D.A cancer targeted gold nanoparticles based MRI contrast agent
318Ryan C. McAllisterPh.D.2018Jessie Roman, M.D.Perinatal nicotine with or without early life influenza infection leads to lung dysfunction with age
317Julie A. GosneyPh.D.2018Brian P. Ceresa, Ph.D.EGFR signaling from the early endosome
316Cierra N. SharpPh.D.2018Leah J. Siskind, Ph.D.A clinically relevant mouse model of cisplatin-induced kidney injury
315Alyssa S. LaunM.S.2018Zhao-Hui (Joe) Song, Ph.D.A study of GPR3, GPR6, and GPR12 as novel molecular targets for cannabidiol
314Hongxue ShiPh.D.2018Matthew C. Cave, M.D.The effects of polychlorinated biphenyls exposure on non-alcoholic fatty liver disease: Role of aryl hydrocarbon receptor
313

Anna L. Lang

Ph.D.2018Juliane I. Beier, Ph.D.Vinyl chloride enhances diet-induced liver injury via metabolic dyshomeostasis: Critical role of mitochondria
312Joshua M. RoyalM.S.2018Nobuyuki Matoba, Ph.D.

Therapeutic potential of a plant-made cholera toxin B subunit variant for the treatment of ulcerative colitis

311

Adrienne M. Bushau-Sprinkle

M.S.2018Eleanor Lederer, M.D.Loss of the Na+ H- exchange regulatory Factor 1 results in increased susceptibility to cisplatin-induced acute kidney injury
310

Jamie L. Young

M.S.2018Gavin E. Arteel, Ph.D.

A model to study the effects of whole life chronic exposure to arsenic or cadmium on the development of adult metabolic syndrome: Initial characterization of hepatic changes

309

Marc M. Dwenger

M.S.2018Bradley B. Keller, M.D.

Maturation of human induced pluripotent stem cell derived  engineered cardiac tissues using channel rhodopsin transfection and chronic optical pacing

308

J. Caleb Greenwell

Ph.D.2017Jessie Roman, M.D.

Age-related host factors regulate lung cancer progression

307

Marcus W. Stepp

Ph.D.2017David W. Hein, Ph.D.

Role of human arylamine N-acetyltransferase 1 in tumorigenesis and cancer biology

306

Lauren G. Poole-Hardy

Ph.D.2017Gavin E. Arteel, Ph.D.

Novel insight into the liver-lung axis in alcohol-enhanced acute lung injury

305

Zimple D Kurlawala

Ph.D.2017Levi J. Beverly, Ph.D.

UBQLN1: A multi-domain protein with multiple functions

304

Tuo Shao

Ph.D.2017Wenke Feng, Ph.D.

The role of HIF-1α in intestinal epithelial barrier function in alcoholic liver disease

303

Laila Al-Eryani

Ph.D.2017J. Christopher States, Ph.D.

miRNA expression changes in arsenic-induced skin cancer in vitro and in vivo  

302

J. Mason Hoffman

M.S.2017J. Christopher States, Ph.D.

Targeting the major regulator of mitosis 

301

Ashley M. Mudd

M.S.2017Ramesh C. Gupta, Ph.D.

Prevention and treatment of familial adenomatous polyposis and colorectal cancer by bilberry-derived anthocyanidins

300

Divya Karukonda

M.S.2017Ramesh C. Gupta, Ph.D.

Advances in tumor-targeted therapy using nanomedicine

299

Rachel M. Speer

M.S.2017John P. Wise, Sr., Ph.D.

The comparative cytotoxicity and genotoxicity of hexavalent chromium in humans and sea turtles

298

Tess V. Dupre

Ph.D.2017Leah J. Siskind, Ph.D.

Sphingolipids in models of kidney injury and disease

297

Elizabeth M. Hollis

M.S.2017Ayman El-Baz, Ph.D.

Diffusion-weighted magnetic resonance imaging in diagnosing graft dysfunction: a non-invasive alternative to renal biopsies

296

Al Hassan Kyakulaga

M.S.2017Ramesh C. Gupta, Ph.D.

Withaferin A synergistically enhances the effect of paclitaxel against lung cancer

295Stephan L. WechmanPh.D.2017Kelly M. McMasters, M.D., Ph.D.

Characterization of a mutant oncolytic adenovirus and the role of JNK in enhancing virotherapy

294Nicole M. Jackson-SanterrePh.D.2017Brian P. Ceresa, Ph.D.

Identifying the signaling mechanisms of EGFR-mediated apoptosis

293Jaspreet S. GrewalPh.D.2017Jason A. Chesney, M.D., Ph.D.

Targeting the glucose metabolism of myeloid-derived suppressor cells (MDSCs) to stimulate cancer immunity

292Christine E. DolinM.S.2017Juliane I. Beier, Ph.D.

The effects of moderate alcohol consumption and inflammation on the hepatic matrisome and the renal cortex proteome

291Christopher P. ShidalPh.D.2017Keith R. Davis, Ph.D.

Combating malignant melanoma with the multifaceted soy-derived peptide lunasin

290Aaron M. NeelyPh.D.2017Chi Li, Ph.D.

The interaction of homoserine lactones and paraoxonase 2 modulates cell death signaling and cell proliferation

289Gretchen E. HolzM.S.2016Igor S. Lukashevich, M.D., Ph.D., D.Sc.

Proinflammatory cytokines promote viral replication and cell cycle mediators in arenavirus-induced hepatitis

288Glenn W. VicaryPh.D.2016Jesse Roman, M.D.The role of nicotine, α7 nicotinic acetylcholine receptors and extracellular matrix remodeling in pulmonary fibrosis
287Aditya S. BarveM.S.2016Levi J. Beverly, Ph.D.

Establishing a clinically relevant mouse model of human AML to test novel transmethylation inhibitors

286Kevin M. TyoM.S.2016Jill Steinbach-Rankins, Ph.D.

Multipurpose tenofovir disoproxil fumarate electrospun fibers for the prevention of HIV-1 and HSV-2 infections

285Justin L. HallgrenPh.D.2016Michal Hetman, M.D., Ph.D.The role of the nucleolus in neurodegeneration
284Anna L. LangM.S.2016Juliane I. Beier, Ph.D.Vinyl chloride-diet interactions in liver disease: potential roles of autophagy and energy management
283Wei-Yang (Jeremy) ChenPh.D.2016Swati Joshi-Barve, Ph.D. & Craig McClain, M.D.Acrolein is a critical mediator of alcohol-induced liver and intestinal injury in alcoholic liver disease
282Jordan B. FinchM.S.2016Daniel J. Conklin, Ph.D.Air pollution, pulmonary oxidative stress, and the endothelin system in the development of cardiovascular injury
281Julie A. GosneyM.S.2016Brian P. Ceresa, Ph.D.Isolation of EGFR-containing early endosomes
280Cierra N. SharpM.S.2016Leah J. Siskind, Ph.D.Developing a more clinically-relevant mouse model of cisplatin-induced nephrotoxicity
279Dominique Z. JonesPh.D.2016La Creis R. Kidd, Ph.D. & Geoffrey J. Clark, Ph.D.

MicroRNA-186 and metastatic prostate cancer

278Diana V. AvilaPh.D.2016Shirish Barve, Ph.D. & Leila Gobejishvili, Ph.D.Role of phosphodiesterase-4 in alcohol-induced organ injury
277Aaron M. NeelyM.S.2016Chi Li, Ph.D.Modulation of cell death signaling and cell proliferation by the interaction of homoserine lactones and paraoxonase 2
276Hridgandh DondePh.D.2015Shirish Barve, Ph.D.Mechanisms and intervention strategies for alcohol and HIV-antiretroviral therapy-induced liver injury
275Keegan J. BaldaufPh.D.2015Nobuyuki Matoba, Ph.D.Studies on the impacts of a plant-made recombinant cholera toxin B subunit on the gastrointestinal tract
274Pritesh P. KumarPh.D.2015Zhao-Hui (Joe) Song, Ph.D.Searching for novel ligands for the cannabinoid and related receptors
273Zimple D. KurlawalaM.S.2015Levi J. Beverly, Ph.D.Regulation of receptor tyrosine kinases by UBQLN1
272Stephen L. WechmanM.S.2015Kelly M. McMasters, M.D., Ph.D.Improved oncolytic virotherapy by increasing virus spread within tumors
271Lauren G. PooleM.S.2015Gavin E. Arteel, Ph.D.Alcohol-enhanced acute lung injury: Role of plasminogen activator inhibitor-1 and the transitional extracellular matrix
270Harshulkumar M. PanditM.S.2015Robert C.G. Martin II, M.D., Ph.D.Identifying hepatocellular carcinoma (HCC) cells with cancer stem cell-like properties
269Nicole M. JacksonM.S.2015Brian P. Ceresa, Ph.D.The regulation and mechanisms of EGFR-mediated apoptosis in MDA-MB-468 cells
268Tess V. DupreM.S.2015Leah J. Siskind, Ph.D.Identifying novel renoprotective strategies for cisplatin-induced AKI
267Samantha M. CarlisleM.S.2015David W. Hein, Ph.D.Investigating pathway changes associated with varying levels of human arylamine N-acetyltransferase 1 (NAT1) activity
266Tareq Al-MaqtariPh.D.2015Aruni Bhatnagar, Ph.D. & Kyung Hong, Ph.D.Promoting differentiation and survival of human c-kit+ cardiac progenitor cells ex vivo
265J. Caleb GreenwellM.S.2015Jesse Roman, M.D.Role of nicotinic acetylcholine receptors in lung cancer
264Veronica L. MasseyPh.D.2014Gavin E. Arteel, Ph.D.Extracellular matrix proteins and the liver-lung axis in disease
263Christopher G. EnglandPh.D.2014Hermann B. Frieboes, Ph.D.Study of novel nanoparticle transport and drug release for cancer treatment
262Banrida WahlangPh.D.2014Matthew C. Cave, M.D.Evaluating the effects of polychlorinated biphenyls in non-alcoholic fatty liver disease
261Christopher P. ShidalM.S.2014Keith R. Davis, Ph.D.Lunasin reduces the melanoma stem cell population in-vitro and inhibits tumor proliferation in-vivo
260Dominique Z. JonesM.S.2014La Creis R. Kidd, Ph.D.The role of inflammatory and immune response-related sequence variants and miR-186 in prostate cancer
259Diana V. AvilaM.S.2014Shirish Barve, Ph.D. & Leila Gobejishvili, Ph.D.Pathogenic role of PDE4 in the development of alcohol induced hepatic steatosis
258Wei-Yang (Jeremy) ChenM.S.2014Craig J. McClain, M.D.The pathogenic role of acrolein in alcoholic liver disease
257Marcus W. SteppM.S.2014David W. Hein, Ph.D.Inducible tumor difference between rapid and slow rat Nat2 congenic Fischer 344 rats administered methyl-nitrosourea
256Morgan L. StathemM.S.2014Levi J. Beverly, Ph.D. & Leah J. Siskind, Ph.D.Building a metabolic bridge between glycolysis and sphingolipid biosynthesis: Implications for cancer
255Christopher L. BartonPh.D.2014Kenneth E. Palmer, Ph.D.Evaluation of the safety and pharmacokinetic profile of the broad spectrum antiviral lectin griffithsin
254Ryan C. McAllisterM.S.2014Colleen B. Jonsson, Ph.D.Development of models for the study of the molecular mechanisms of host restriction and adaptation of hantaviruses
253Zachary J. PritchardM.S.2014Uma Sankar, Ph.D.Bone strength and architecture: pharmacological targeting of CaMKK2 as a method for enhancing bone quality
252Laila Al-EryaniM.S.2014Matthew C. Cave, M.D.The role of pesticides in non-alcoholic fatty liver disease (NAFLD)
251Melissa E. SkibbaM.S.2014Lu Cai, M.D., Ph.D.Preventive effect of non-mitogenic acidic fibroblast growth factor on diabetes-induced testicular cell death
250Justin L. HallgrenM.S.2014Michal Hetman, M.D., Ph.D.The role of the nucleolus in neurodegeneration
249Pei-Hsin (Penny) ChengPh.D.2013Kelly M. McMasters, M.D., Ph.D.Cyclin E induction and oncolytic replication of E1B-deleted adenoviruses
248Amanda B. LasnikM.S.2013Kenneth E. Palmer, Ph.D.Preclinical safety assessment of griffithsin-based vaginal microbicides
247Alex C. BelshoffPh.D.2013Teresa Fan, Ph.D.Probing the anti-cancer mechanism of selenite: a metabolic approach
246Robin H. SchmidtPh.D.2013Gavin E. Arteel, Ph.D.Olanzapine-induced liver injury: Direct metabolic effects, exacerbation by high-fat diet, and protection with sulforaphane
245Christopher G. EnglandM.S.2013Hermann B. Frieboes, Ph.D.Optimization of drug uptake into solid tumors using an integrated experimental/computational modeling approach
244Glenn W. VicaryM.S.2013Jesse Roman, M.D.The role of α7 nicotinic acetylcholine receptors in lung injury and repair
243Hridgandh DondeM.S.2013Shirish Barve, Ph.D.Role of ethanol as a cofactor in HAART induced hepatic steatosis and injury
242Veronica L. MasseyM.S.2012Gavin E. Arteel, Ph.D.Integrin inhibitor cyclorgdfv blunts enhanced LPS-induced liver injury caused by ethanol in mice
241Keegan J. BaldaufM.S.2012Gavin E. Arteel, Ph.D.Acetaldehyde dehydrogenase 2 (ALDH2) activation protects hepatocytes from mitochondrial damage and death caused by 4-hydroxynonenal
240Madhuvanti PatilPh.D.2012Shirish Barve, Ph.D.The role of the transmethylation pathway in the regulation of cell death in leukemic CD4+ T cells
239Colins O. EnoPh.D.2012Chi Li, Ph.D.The role of endogenous Bcl-xL in regulation of apoptotic signaling pathways
238Akshata MoghePh.D.2012Shirish Barve, Ph.D.Role of chromatin remodeling in curcumin-mediated regulation of gene expression in hepatocellular carcinoma
237Carmine S. LeggettPh.D.2012David W. Hein, Ph.D.Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression
236Daniel FioretM.S.2012Jesse Roman, M.D.Idiopathic pulmonary fibrosis: Diagnosis, management, and the search for a cure
235Tareq Al-MaqtariM.S.2012Uma Sankar, Ph.D.Approaches in the treatment of Parkinson's disease: A focus on stem cell-based therapies
234Banrida WahlangM.S.2012Matthew Cave, M.D.Polychlorinated biphenyl 153 exacerbates nonalcoholic fatty liver disease in C57BL/6 mice
233Huihui WuM.S.2012Al Cunningham, Ph.D.Structure-activity relationship model for estrogen receptor ligands
232Elaina Marie ChambersPh.D.2012Shirish Barve, Ph.D.The role of phosphodiesterase 4 in diabetic inflammation
231Pritesh P. KumarM.S.2011Zhao-Hui (Joe) Song, Ph.D.Searching for novel ligands for cannabinoid and related receptors
230Benjamin M. RisnerM.S.2011Richard Goldstein, M.D., Ph.D.Pharmacists as mid-level healthcare providers and the clinical results of a pharmacist-led diabetes disease management program
229Stephanie A. MathewsPh.D.2011Shirish Barve, Ph.D.Role of HDACs and SAM in interferon-alpha signaling and epigenetic regulation of anti-HCV gene expression
228Erica N. RogersPh.D.2011J. Christopher States, Ph.D.The role of curcumin in response to BPDE-induced DNA damage in human lung epithelial cells
227Katherine S. BourcyPh.D.2011Y. James Kang, Ph.D.Mechanistic insights into copper-induced regression of heart hypertrophy
226Ntube Nini Olive NgalamePh.D.2011J. Christopher States, Ph.D.Arsenic-induced developmental changes in the liver and adult cardiovascular disease
225Shelia A. ArnoldPh.D.2011Theo Hagg, M.D., Ph.D.Roles of 5HT1A receptor in CNS neurogenesis and ADAM21 in spinal cord injury
224Clarisse S. MuenyiPh.D.2011J. Christopher States, Ph.D.Mitigating cisplatin resistance in ovarian cancer
223Lori M. MillnerPh.D.2011David W. Hein, Ph.D.Functional analysis of N-acetyltransferase (NAT1*14B and NAT1*10) in complete NATb and NATa mRNA
222Pei-Hsin (Penny) ChengM.S.2011Kelly M. McMasters, M.D., Ph.D.Adenovirus-induced cyclin E activates CDK2 for virus replication
221Lindsey Jay StallonsPh.D.2011J. Christopher States, Ph.D.DNA polymerase iota promotes G2/M checkpoint activation and genetic stability after UV-induced DNA damage
220Shyam Sunder BansalPh.D.2011Ramesh C. Gupta, Ph.D.Development and evaluation of polymeric implants of curcumin for enhanced chemopreventive activity
219Christopher L. BartonM.S.2011Kenneth E. Palmer, Ph.D.Profile of systemic treatment with the antiviral lectin griffithsin in guinea pigs
218Pengxiao CaoPh.D.2011Ramesh C. Gupta, Ph.D.Prevention and treatment of lung cancer by green tea polyphenols
217Gilandra K. RussellPh.D.2011Ramesh C. Gupta, Ph.D.Sustained systemic delivery of chemopreventive agents in inhibiting dibenzo[a,l]pyrene-induced DNA adducts in the lungs of A/J mice
216Jianxun WangPh.D.2011Paul N. Epstein, Ph.D.Cardiac abnormalities after transaortic constriction are worsened by changing glucose metabolism and benefited by repair of mitochondrial DNA
215Robin H. SchmidtM.S.2011Gavin E. Arteel, Ph.D.Sulforaphane prevents acetaminophen-induced hepatic injury in mice
214Nicole A. LavenderPh.D.2010La Creis R. Kidd, Ph.D.The role of genetic and environmental oxidative stress factors in prostate cancer
213Lu YangPh.D.2010Paul N. Epstein, Ph.D.Adriamycin nephrotoxicity is reduced by metallothionein over-expression and kidney gene expression is modified by diabetes in the OVE26 diabetic model
212Afsoon MoktarPh.D.2010Ramesh C. Gupta, Ph.D.Cigarette smoke, DNA damage and repair in human cervical and vaginal cells in vitro and ex vivo
211Carmine S. LeggettM.S.2010David W. Hein, Ph.D.Effects of CYP1A2, NAT1, and NAT2 genetic variants in nucleotide excision repair-deficient human fibroblasts: Implications for toxicological risk from environmental arylamines
210Matthew R. ZajackM.S.2010J. Christopher States, Ph.D.Arsenic in drinking water causes gene expression changes in the liver related to inflammation and metabolic dysfunction and accelerates atherosclerosis in APOE-/- mice
209Akshata MogheM.S.2010Shirish Barve, Ph.D.Curcumin reactivates epigenetically silenced tumor suppressor gene tissue factor pathway inhibitor-2 in hepatocellular carcinoma cells
208Madhuvanti PatilM.S.2010Shirish Barve, Ph.D.Role of the transmethylation pathway in the regulation of cell death in T leukemic cells
207Colins O. EnoM.S.2010Chi Li, Ph.D.Mechanism of regulation of apoptosis by the BCL-2 proteins BCL-XL and BCL-XS
206Christelle K. KamgaPh.D.2010Yang Wang, M.D., Ph.D.GSH transport through the dicarboxylate carrier: A key component in UCP4-mediated antioxidants effects in neuronal-like PC12 cells
205John PhiliposePh.D.2010Michele Pisano, Ph.D.Craniofacial anomalies: sensitivity of the neural crest to altered folate metabolism
204Aisha Isabelle BagshawM.S.2010Aruni Bhatnagar, Ph.D.Potential cardiotoxic impact of aldehydes in the progression of atherosclerosis
203LaSharon D. MosleyPh.D.2009James W. Lillard, Jr., Ph.D.Mechanisms mediated by CXCL12 signaling through CXCR4 and CXCR7 in breast cancer
202J. Phillip KaiserPh.D.2009Gavin E. Arteel, Ph.D.The role of PKC-epsilon in models of alcohol- and toxin-induced liver disease
201Ntube Nini Olive NgalameM.S.2009J. Christopher States, Ph.D.Arsenic-induced developmental changes in the liver and adult cardiovascular disease
200Pengxiao CaoM.S.2009Ramesh C. Gupta, Ph.D.Effect of green tea catehins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure activity relationship
199Shyam Sunder BansalM.S.2009Ramesh C. Gupta, Ph.D.A novel implantable drug delivery system of curcumin for cancer chemoprevention
198Jean-Claude NzimulindaPh.D.2009Zhao-Hui (Joe) Song, Ph.D.Ligand binding, activation, and dimerization of CB2 cannabinoid receptor
197Yang ZhouPh.D.2008Y. James Kang, Ph.D.Copper-induced regression of cardiomyocyte hypertrophy through alteration of VEGF/VEGFR pathways
196Nason P. SchoolerM.S.2008John W. Eaton, Ph.D.The use of the reducing agent N-(2-mercaptopropionyl)glycine to detoxify oxidized lipids in atherosclerotic lesions
195Katharine Shumate RichardsonPh.D.2008Wayne Zundel, Ph.D.Regulation of placental ribonuclease inhibitor by tumor suppressor Von Hippel-Lindau
194Stephanie A. MathewsM.S.2008Shirish Barve, Ph.D.Impaired SAM metabolism and IFNα antiviral signaling: Relevance to hepatitis C virus
193Robert C.G. Martin, IIPh.D.2008David W. Hein, Ph.D.Polymorphisms in manganese superoxide dismutase as a risk factor for cancer
192Nicole A. LavenderM.S.2008La Creis R. Kidd, Ph.D.Joint modifying effects of variant oxidative stress factors in relation to prostate cancer
191Emily Roberts EspositoPh.D.2008Michele Pisano, Ph.D.In vivo and in vitro models for cigarette smoke-induced low birth weight and other adverse developmental outcomes
190Christina Blume ClarkPh.D.2008Evelyne Gozal, Ph.D.The role of HSP90 in PC-12 cell survival
189Elaina Marie ChambersM.S.2008Shirish Barve, Ph.D.Immune dysregulation and diabetes: A potential role of phosphodiesterases
188Thomas J. SchlierfM.S.2008David W. Hein, Ph.D.Role of N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in breast cancer risk with exposure to aromatic and heterocyclic amine carcinogens
187Katherine S. BourcyM.S.2008Y. James Kang, Ph.D.The role of vascular endothelial growth factor receptors in copper-induced regression of cardiac hypertrophy
186Carl Alexander CarrasquerPh.D.2008Zhao-Hui (Joe) Song, Ph.D.Activation and regulation of cannabinoid receptors
185Clarisse S, MuenyiM.S.2008J. Christopher States, Ph.D.Improving the efficacy of platinum chemotherapy against ovarian cancer
184Lindsey Jay StallonsM.S.2008W. Glenn McGregor, M.D.Mutagenic and tumor suppressor functions of DNA polymerase iota in mammalian cells
183Lori M. MillnerM.S.2008David W. Hein, Ph.D.Effect of N-acetyltransferase (NAT1) polymorphism on mutagenesis and DNA adduct formation
182Shankang MaM.S.2008Y. James Kang, Ph.D.Metallothionein gene therapy for chemically-induced liver fibrosis
181Jean-Claude NzimulindaM.S.2008Zhao-Hui (Joe) Song, Ph.D.Residues accessible in the binding site crevice of transmembrane helix 2 of CB2 cannabinoid receptor
180Erica N. RogersM.S.2008J. Christopher States, Ph.D.The modulation of DNA damage by curcumin
179Nicholas B.  WatsonPh.D.2008W. Glenn McGregor, M.D.RAD18 is recruited to stalled DNA replication forks and is required for recruitment of accessory translesion synthesis proteins
178Xiaoyan (Susan) ZhangPh.D.2008David W. Hein, Ph.D.Characterization of N-acetyltransferase 1 (NAT1) expression in breast cancer
177Ya Fatou NjiePh.D.2007Zhao-Hui (Joe) Song, Ph.D.Cannabinoids as potential therapeutic agents for glaucoma
176Christelle K. KamgaM.S.2007Yang Wang, M.D., Ph.D.UCP4 is a key regulator of mitochondrial antioxidant defense in rat PC12 cells
175Jianxun WangM.S.2007Paul N. Epstein, Ph.D.The changes of fructos-2,6-biphosphate level in transgenic mice causing cardiomyopathy
174Joshua M. ThornburgPh.D.2007Jason A. Chesney, M.D., Ph.D.Identification of aspartate aminotransferase as a novel target for anti-neoplastic research
173Samuel C. McNeelyPh.D.2007J. Christopher States, Ph.D.Sensitivity to sodium arsenite depends upon susceptibility to mitotic arrest-associated apoptosis
172Jason M. WalravenPh.D.2007David W. Hein, Ph.D.Computational and functional analyses of human and rat N-acetyltransferase genetic variants N-acetyltransferase genetic variants
171J. Phillip KaiserM.S.2007Gavin E. Arteel, Ph.D.The role of PKC-epsilon in alcoholic liver disease
170Agata M. HabasPh.D.2007Michal Hetman, M.D., Ph.D.The role of GSK3β  and NFATc4 in NMDA-mediated neuronal survival
169B. Frazier TaylorPh.D.2007J. Christopher States, Ph.D.Arsenite inhibition of mitotic progression
168LaSharon D. MosleyM.S.2007Richard E. Goldstein, M.D., Ph.D.Estrogen receptors in thyroid cell proliferation
167Lu YangM.S.2007Paul N. Epstein, Ph.D.Protection by metallothionein from adriamycin induced nephropathy in mice and gene expression profiling during progression of diabetic nephropathy
166Chad A. DumstorfPh.D.2007W. Glenn McGregor, M.D.Participation of mouse DNA polymerases iota, eta, and rev1 in translesion synthesis of carcinogen induced DNA adducts and carcinogenesis
165Kristin J. MetryPh.D.2007David W. Hein, Ph.D.Role of N-acetyltransferase 2 polymorphism in DNA adduct formation and mutagenesis by aromatic and heterocyclic amine carcinogens
164Jin LiuPh.D.2007Michael E. Brier, Ph.D.Design evaluation for pharmacokinetic studies in patients with renal impairment
163Kevyn E. MertenPh.D.2007Y. James Kang, Ph.D.Effect of zinc on doxorubicin-induced activation of the calcineurin signaling pathway and the relation to myocardial cell death and hypertrophy
162Alex CarrasquerM.S.2006Zhao-Hui (Joe) Song, Ph.D.The effects of polymorphisms on the function of the CB2 cannabinoid receptor
161Afsoon MoktarM.S.2006Ramesh C. Gupta, Ph.D.Cigarette smoking as a major cofactor in human cervical cancer
160Emily Roberts EspositoM.S.2006M. Michele Pisano, Ph.D.Low birth weight-Consequences of maternal tobacco smoke exposure during embryonic and fetal development
159Nstang Miranda NebanePh.D.2006Zhao-Hui (Joe) Song, Ph.D.Structure-activity relationship of the CB1 and CB2 cannabinoid receptors
158Yang ZhouM.S.2006Y. James Kang, Ph.D.Copper inhibition of hydrogen peroxide-induced hypertrophy in H9C2 embryonic rat cardiac cells
157Xiaoqiang (Steven) XuM.S.2006Theresa Whei-Mei Fan, Ph.D.TrxR SECIS RNA synthesis and biophysical characterization
156Rundong (Ray) ZhangPh.D.2006Zhao-Hui (Joe) Song, Ph.D.Structure and function of CB2 cannabinoid receptors
155Sheila A. MullinsM.S.2006Paul N. Epstein, Ph.D.Effects of fructose-2,6-bisphosphate on Akt phosporylation and insulin signaling in cardiomyocytes
154Joshua M. ThornburgM.S.2006Jason A. Chesney, M.D., Ph.D.Role of lactate dehydrogenase A (LDH-A) in oncogenic transformation; Revisiting a classic enzyme
153Wei (Wendy) Yuan ChangPh.D.2006Theresa S. Chen, Ph.D.Mechanism of 4-hydroxynonenal induced toxicity in Jurkat CD4+ T lymphocytes
152Katharine S. RichardsonM.S.2006Wayne S. Zundel, Ph.D.Impact of von Hippel-Lindau in regulating ribonuclease activity in renal cell carcinoma
151Yu (Janet) ZangPh.D.2006David W. Hein, Ph.D.Functional characterization and mechanistic studies on single nucleotide polymorphisms of human N-acetyltransferase 2
150Tanvi S. JaniPh.D.2006Shirish Barve, Ph.D.Role of methionine adenosyltransferase II (MAT II) and S-adenosylmethionine (SAMe) in survival of CD4+ T lymphocytes: Relevance to immune dysfunction
149Stephen R. ReevesPh.D.2006David Gozal, M.D.Chronic intermittent hypoxia and respiratory plasticity
148Paul C. PorterPh.D.2005J. Christopher States, Ph.D.Discovery and functional analysis of XPA polymorphisms and use of telomerase immortalized cells for nucleotide excision repair studies
147Ya Fatou NjieM.S.2005Zhao-Hui (Joe) Song, Ph.D.Effects of the endogenous cannabinoid, noladin ether on aqueous humor outflow facility mediated by the CB1 cannabinoid receptor
146Molly Anne DavisM.S.2005Gavin E. Arteel, Ph.D.Characterization of recovery from liver damage by choline deficiency:  Effect of biochemical modulators of lipid metabolism?
145E. Cristian CampianPh.D.2005Frederick W. Benz, Ph.D.Acute acrylonitrile toxicity:  Mechanistic Studies
144Anwar HusainPh.D.2005David W. Hein, Ph.D.Regulatory control regions of human arylamine N-acetyltransferase 1 and 2:  Implications for genetic predisposition to breast cancer
143Xiaoyan (Susan) ZhangM.S.2005David W. Hein, Ph.D.Role of N-acetyltransferase (NAT) polymorphism on 4,4’-methylene bis (2-chloroaniline) and 4,4’-methylenedianiline (MDA) acetylation, MDA hepatotoxicity and a proposal to study NAT expression in breast cancer
142Gilandra K. RussellM.S.2005Gavin E. Arteel, Ph.D.Protection of cultured hepatocytes from hypoxic death by ATP-delivery with lipid vesicles
141Samuel C. McNeelyM.S.2005J. Christopher States, Ph.D.Arsenic:  A potential chemotherapeutic for melanoma
140Tanvi S. JaniM.S.2005Shirish Barve, Ph.D.Methionine adenosyltransferase IIA (MAT IIA) and S-adenosylmethionine (SAMe) are critical for the survival of CD4+ T lymphocytes
139Jin LiuM.S.2005Michael E. Brier, Ph.D.An evaluation of pharmacokinetic study design for describing drug disposition in renal failure
138Kevyn E. MertenM.S.2005Y. James Kang, Ph.D.Molecular mechanisms of metallothionein protection from adriamycin cardiotoxicity
137Jason M. WalravenM.S.2005David W. Hein, Ph.D.Investigations of N-acetyltransferases in human hepatocytes and rat models
136Nicholas B. WatsonM.S.2005W. Glenn McGregor, M.D.The ubiquitin ligase RAD18 is implicated in mutagenic translesion synthesis of DNA damage in human cells
135Prachi T. HoteM.S.2004Shirish Barve, Ph.D.Ethanol mediated loss of MAT2A (methionine adenosylmethyltransferase) expression and SAMe (S-adenosylmethionine) biosynthesis induced FAS-mediated CD4+ T lymphocyte death: Potential mechanism(s) for alcohol mediated immunotoxicity
134Ntsang Miranda NebaneM.S.2004Zhao-Hui (Joe) Song, Ph.D.Effects of D3.49N mutations on ligand binding and activation of the CB1 and CB2 cannabinoid receptors
133Xia (Clare) ShenPh.D.2004Paul N. Epstein, Ph.D.Mitochondrial damage and biogenesis in diabetic heart and protection by overexpression of manganese superoxide dismutase
132Chad A. DumstorfM.S.2004W. Glenn McGregor, M.D.Mutagenesis of induced tumors in murine lung
131Yuanqi ZhuPh.D.2004David W. Hein, Ph.D.Human NAT1 genetic polymorphisms: coding region & non-coding region
130Agata M. HabasM.S.2004Michal Hetman, M.D., Ph.D.The role of nuclear factors of activated T-cells (NFAT) in neuronal death
129Yu (Cindy) WangM.S.2004David Gozal, M.D.Cooperative effects of amyloid beta (25-35) and hypoxia-reoxygenation on cell death in primary cultured mouse neurons of cerebral cortex
128Christopher R. CunninghamPh.D.2004Steven R. Myers, Ph.D.Hemoglobin adducts and the role of genotype in the modification of risk associated with tobacco smoke exposure to the fetus
127Xiaoyan (Nina) LiPh.D.2004Paul N. Epstein, Ph.D.The roles of pancreatic beta cell antioxidants in islet transplantation and type 1 diabetes
126Kristin J. MetryM.S.2004David W. Hein, Ph.D.NAT polymorphism in breast cancer risk
125Wei (Wendy) Yuan ChangM.S.2004Theresa S. Chen, Ph.D.Mechanism of oxidative stress induced cell toxicity
124Jennifer A. LoehleM.S.2004David W. Hein, Ph.D.Pediatric pharmacogenetic studies:  The advent of genomics, clinical implications and current initiatives in research
123April K. HartfordPh.D.2004Nicholas A. Delamere, Ph.D.NA,K-ATPase Alpha 2: Its role in calcium homeostasis, signaling and cell survival in astrocytes
122Laila ElsherifPh.D.2004Y. James Kang, Ph.D.Dietary copper restriction-induced cardiomyopathy and its reversibility in mice
121Jian LiPh.D.2003John W. Eaton, Ph.D.Oxygen toxicity and mitochondrial metabolism
120Yu (Janet) ZangM.S.2003David W. Hein, Ph.D.Mechanistic studies on the T341C (Ile114Thr) single nucleotide polymorphism of human N-acetyltransferase 2
119Rundong (Ray) ZhangM.S.2003Zhao-Hui (Joe) Song, Ph.D.Cysteine 89(2.69) in the second transmembrane domain of human CB2 receptor is exposed in the ligand binding crevice
118Hainan ChenPh.D.2003Paul N. Epstein, Ph.D.Studies on the effects of pancreatic beta cell antioxidant transgenes on experimental models of diabetes
117Terry L. Wright, Jr.M.S.2003Gavin E. Arteel, Ph.D.The TNFalpha paradox in ischemic heart disease
116Denise R. ClarkM.S.2003W. Glenn McGregor, M.D.Ribozyme-mediated REV1L inhibition reduces UV-induced mutations in the human HPRT gene
115Paul C. PorterM.S.2003J. Christopher States, Ph.D.Detection and functional analysis of polymorphic XPA alleles
114Jason C. LambertPh.D.2003Y. James Kang, Ph.D.Zinc inhibition of acute ethanol-induced liver injury
113Yuanqi ZhuM.S.2002David W. Hein, Ph.D.Functional characterization of NAT gene polymorphisms
112Xiaoyan (Nina) LiM.S.2002Paul N. Epstein, Ph.D.Metallotheionein overexpression prolongs grafts survival in the early phase of pancreatic islet transplantation
111Bradley G. BrewerM.S.2002Peter P. Rowell, Ph.D.Short-term distribution of nicotine in the rat
110Xia (Clare) ShenM.S.2002Paul N. Epstein, Ph.D.Proteomics and morphology demonstrate mitochondrial changes in diabetic cardiomyopathy
109Hana H. KhaledM.S.2002William M. Pierce Jr., Ph.D.Osteoporosis: An overview of prevention, genetics, and treatment
108Hainan ChenM.S.2002Paul N. Epstein, Ph.D.Metallothionein protection against streptozotocin induced pancreatic beta cell damage and diabetes
107Jason R. NealePh.D.2002William M. Pierce Jr., Ph.D.Bone-targeted estrogens:  Structure-activity relationships and mechanistic studies
106Jian LiM.S.2002John W. Eaton, Ph.D.Mitochondrial metabolism and oxygen toxicity
105Yining HouPh.D.2002Nicholas A. Delamere, Ph.D.The influence of cytoplasmic calcium on H+-ATPase; and the influence of H+-ATPase inhibition on sodium transport in non-pigmented ciliary epithelial cells
104Alfred A. Jacobs, Jr.Ph.D.2001Michael E. Brier, Ph.D.Influence of cyclosporin on renal hemodynamics in the isolated perfused kidney
103Jason C. LambertM.S.2001Y. James Kang, Ph.D.Zinc inhibition of caspase-3 activation does not prevent apoptotic cell death
102E. Cristian CampianM.S.2001Frederick W. Benz, Ph.D.Acute acrylonitrile toxicity: inhibition of glyceraldehyde- 3-phosphate dehydrogenase activity in vitro
101Laila ElsherifM.S.2001Y. James Kang, Ph.D.Metallothionein protection against cadmium cardiotoxicity
100R. Scot PaynePh.D.2001Avital Schurr, Ph.D.The corticosterone hypothesis of hyperglycemia-enhanced cerebral ischemic damage
99Xin FuPh.D.2001Walter M. Williams, M.D., Ph.D.Para-Aminophenol-induced hepatotoxicity in hamsters
98Xichun SunPh.D.2001Y. James Kang, Ph.D.Metallothionein protection of the heart from ischemia/reperfusion injury: Cellular and molecular mechanisms
97John P. HennionM.S.2001Rif El-Mallakh, M.D.Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage
96April K. HartfordM.S.2000Nicholas A. Delamere, Ph.D.Calcium signaling in astrocytes of the optic nerve head; Evidence for a role for Na,K-ATPase Alpha-2
95Jason R. NealeM.S.2000William M. Pierce Jr., Ph.D.A novel bone selective estrogen:  A candidate compound for the treatment of osteopenia
94Adrian J. FretlandPh.D.2000David W. Hein, Ph.D.Pharmacogenetics of heterocyclic amine carcinogenesis
93Joseph A. Spinnato, IIIPh.D.1999Steven R. Myers, Ph.DMicrosomal metabolism and tissue distribution of N-Methyl-N-2,4,6-tetranitroaniline (tetryl)
92Matthew A. LeffPh.D.1999David W. Hein, Ph.D.Molecular genetics of N-acetyltransferases and prostate cancer
91Jian CaiPh.D.1999Harrell E. Hurst, Ph.D.N-(carboxymethyl)valine adduct in hemoglobin: A biomarker of advanced glycation end product formation and oxidative stress
90Jungyu LiPh.D.1999Frederick W. Benz, Ph.D.Acrylonitrile acute intoxication: Toxicodynamics and the effects of antidotes
89Nicolas MeloM.S.1999Walter M. Williams, M.D., Ph.D.Prevention of acetaminophen-induced hepatotoxicity by S-(2-hydroxyethylmercapto)-L-cysteine
88David A. HasselbacherM.S.1998George R. Aronoff, M.D.The development of a dosing model for the anticoagulant heparin using neural networks
87Emiko Lynn KreklauPh.D.1997Y. James Kang, Ph.D.Cross-resistance to adriamycin in cadium-resistant human lung carcinoma A549 cells
86Qiang WuPh.D.1997Nicholas A. Delamere, Ph.D.Studies of carbonic anhydrases and intracellular pH regulation in non-pigmented ciliary epithelial cells
85Mary Manlei LiPh.D.1997Avital Schurr, Ph.D.Global cerebral ischemia and neuroprotection
84Sue HanPh.D.1997Laurence A. Carr, Ph.D.Regulation of the dopamine neuronal transporter in the striatum
83Chandrika SrinivasanPh.D.1997Theresa S. Chen, Ph.D.Prevention of acetylaminophen-induced toxicity by n-propylthiazolidine carboxylic acid
82Yining HouM.S.1997Nicholas A. Delamere, Ph.D.Solutes transport mechanism in nonpigmented ciliary epithelium: influence of ascorbic acid uptake on sodium transport
81Maureen LiPh.D.1996Peter P. Rowell, Ph.D.Effect of chronic nicotine treatment on rat brain nicotine acetylcholine receptors
80Ray KemperPh.D.1995Harrell E. Hurst, Ph.D.Effects of xenobiotic induction in metabolic activation and detoxification of ethyl carbamate
79Hong SongPh.D.1994Theresa S. Chen, Ph.D.Mouse and rat differences in p-aminophenol-induced liver and kidney toxicities
78Jing DongPh.D.1994Nicholas A. Delamere, Ph.D.Solute transport mechanism in non-pigmented ciliary epithelium
77Yun MengPh.D.1994Walter M. Williams, M.D., Ph.D.Elimination of uridine, thymidine and thymine by the isolated perfused rat liver
76David B. GazakPh.D.1993Walter M. Williams, M.D., Ph.D.Pharmacological modulation of hepatic pyrimidine metabolism
75Cathy Ann Rouze SpigarelliM.S.1993Carlo Tamburro, M.D.An investigation of nickel toxicity: an invitro study with  escherichia coli
74Di ChenPh.D.1992William M. Pierce Jr., Ph.D.Effects of zinc on bone metabolism
73Qusai Al-MahasnehM.S.1991George R. Rodgers, M.D., Ph.D.The role of activated charcoal in the treatment of acute arsenic poisoning: an in vivo study
72Mary Kathleen King KaysingerPh.D.1991William M. Pierce Jr., Ph.D.Regulation of bone prolyl-4-hydroxylase activity by 2-oxoglutarate
71Rachelle J. Sells GalvinPh.D.1990Warren K. Ramp, Ph.D.Effects of prolyhydroxylase inhibitors extracted from tobacco on bone collagen synthesis
70Mordechai SharirPh.D.1990William M. Pierce Jr., Ph.D.Novel thiadiazole sulfonamide carbonic anhydrase inhibitors as topically effective ocular hypotensive agents (glaucoma)
69Chong ZhangPh.D.1990Guandershan Thind, M.D.Effects of cadmium on the renal and skeletal muscle microcirculation in rats
68James M. Joly IIPh.D.1989Walter M. Williams, M.D., Ph.D.Elimination of 5-ethylpyridimidines and 5-methylpyrimidines by the isolated perfused rat liver
67Mark J. KlanPh.D.1988Donald E. Nerland, Ph.D.Microsomal carbinol dehydrogenase: isolation and possible role in xenobiotic toxicity
66Karl G. CsakyPh.D.1987Walter M. Williams, M.D., Ph.D.Metabolism of fluorodeoxyuridine by the isolated perfused rat liver
65Charles R. Ashby, Jr.Ph.D.1987Laurence A. Carr, Ph.D.Alteration of serotoninergic mechanisms in premenstrual syndrome (PMS)
64Elizabeth D. DunlapPh.D.1987Michael A. Pfeifer, M.D.Biochemical and physiological change associated with diabetes in the diabetic BB rat
63Fu-Hsiung LinPh.D.1987Walter M. Williams, M.D., Ph.D.Fluorodeoxyuridine catabolism by isolated intestinal and tumor cells
62John J. SchlagerPh.D.1987Harrell E. Hurst, Ph.D.Elimination of acetaminophen by the isolated perfused rat liver in the absence and presence of ethanol
61Michael S. WellsPh.D.1986Donald E. Nerland, Ph.D.Benzene metabolism and toxicity after inhalation exposure: analysis at steady-state
60Donald E. WaltersPh.D.1986Laurence A. Carr, Ph.D.Neurochemical development in the rat following perinatal exposure to marihuana
59Frank LaCretaPh.D.1986Walter M. Williams, M.D., Ph.D.Effect of nucleoside phosphorylase inhibitors on hepatic fluoropyridmidine elimination
58Ching-hsuen ChuM.S.1986Warren K. Ramp, Ph.D.The interrelationships of calcium release and glucose metabolism in bone
57Cynthia L. WabnerPh.D.1986Theresa S. Chen, Ph.D.Aging changes n renal function and structure
56Barbour S. WarrenPh.D.1985Walter M. Williams, M.D., Ph.D.Fluoropyrimidine disposition: dose and flow dependence
55Nancy A. MumaPh.D.1985Peter P. Rowell, Ph.D.Pharmacological, biochemical, morphological and behavioral effects on long-term choline and lecithin administration on the aged central cholinergic nervous system
54Brian J. LukeyPh.D.1985Harrell E. Hurst, Ph.D.Predictors of plasma and tissue concentrations of nortriptyline and 10-OH metabolites
53James A. BlankPh.D.1985Leonard C. Waite, Ph.D.Calcium metabolism by the avian embryo
52Michael J. KelleyPh.D.1984Theresa S. Chen, Ph.D.Effects of 5-Thio-D-glucose on hexose transport and metabolism
51Sayed DaoudPh.D.1984Kee Chang Huang, M.D., Ph.D.Adriamycin: pharmacological studies on liver, kidney and heart
50Brian J. LukeyM.S.1983Harrell E. Hurst, Ph.D.Sources of variability in plasma concentration measurements of nortriptyline and 10-hydroxylated metabolites
49David R. JonesPh.D.1983Harrell E. Hurst, Ph.D.Tissue distribution and toxicokinetics of nortriptyline
48Michael W. McWilliamsM.S.1983Theresa S. Chen, Ph.D.Preservation of microsomal enzyme activities in rat liver by WR-2721 following gamma-irradiation
47Mostafa Z. BadrPh.D.1983Thomas G. Scharff, Ph.D.Cellular penetration and toxicity of benzoic and salicyclic acids
46Christopher J. KemperPh.D.1983Donald E. Nerland, Ph.D.Studies concerning the metabolism and kinetics of benzene in the mouse
45Adrian B. VanBakelPh.D.1983William J. Waddell, M.D.Renal vascular activity of bis substituted (3,4-dimethoxybenzyl)cycloalkylamine and heterocyclic amine hydrochlorides
44Lois E. BolcsakPh.D.1982Donald E. Nerland, Ph.D.Benzene toxicity:emphasis on cytosolic dihydrodiol dehydrogenases
43Stanley D. ErkPh.D.1982Charles H. Jarboe, Ph.D.Toxicokinetic study of 1,2-propanediol dinitrate (PGDN) in the dog
42Michael P. LachancePh.D.1982William J. Waddell, M.D.Whole-body localization of caffeine in the mouse
41Mahmood H. Al-WathiquiPh.D.1982William J. Waddell, M.D.Effects of total parenteral nutrition on pharmacokinetics of drugs
40Sonia R. TellerPh.D.1982Charles H. Jarboe, Ph.D.Synthesis and peripheral cardiovascularization of cis- and trans-2-(3,4-dimethoxybenzyl)cycloalkylamine hydrochlorides
39David R. JonesM.S.1981Harrell E. Hurst, Ph.D.Human pharmacokinetics of clovoxamine
38William M. Pierce, Jr.Ph.D.1981Leonard C. Waite, Ph.D.Effects of heterocyclic sulfonamides on bone metabolism
37Steven M. LeventerPh.D.1981Peter P. Rowell, Ph.D.Investigations of the human placental cholinergic system
36Raymond M. DavidPh.D.1981Donald E. Nerland, Ph.D.Induction of hepatic glutathione S-transferase by ethanol
35David C. MayPh.D.1981Charles H. Jarboe, Ph.D.Some aspects of rabbit and human methylxanthine pharmacokinetics
34Maralyn E. KaufmanPh.D.1980Kee Chang Huang, M.D., Ph.D.Effects of glucagon on the electrical and transport properties of the intestine
33Harriet TobiasPh.D.1980Laurence A. Carr, Ph.D.The interaction of gonadal steroids and catecholamine neurons on release of luteinizing hormone and prolactin
32Margaret M. SchweriPh.D.1980Laurence A. Carr, Ph.D.Inhibition of monoamine synthesis of cycloheximide and anisomycin: possible mechanisms of action
31Gary E. DuncanPh.D.1980Peter P. Rowell, Ph.D.The subcellular distribution and release of newly synthesized acetylcholine in rat cerebral cortical synaptosomes
30Barbara WenzakPh.D.1980Kee Chang Huang, M.D., Ph.D.The renal excretion of methotrexate
29Susan M. WehryM.S.1979Laurence A. Carr, Ph.D.The effects of amnesic agents and d-amphetamine on brain catecholamines in two mouse strains
28Michael J. BannonM.S.1978Charles H. Jarboe, Ph.D.Central nervous system action of 2,5-bis-(3,4-dimethoxybenzyl)cyclopentyl amine, a peripheral dopamine blocking agent
27Mark D. LineberryPh.D.1978Leonard C. Waite, Ph.D.Effects of carbonic anhydrase inhibitors on calcium metabolism
26Paul H. LungrenM.S.1978Laurence A. Carr, Ph.D.The effects of anisomycin and central nervous stimulants on brain catecholamine synthesis
25Andrew M. ConnorM.S.1975Curtis A. Sigdestad, Ph.D.The enhancement of gamma radiation by procarbazine hydrochloride
24Aaron E. LucasM.S.1974John A. Nicholson, Ph.D.The effects of acute and chronic morphine administration on the cardiovascular system of the dog
23Chung Sim KimM.S.1973Kee Chang Huang, M.D., Ph.D.A cerebroventricular perfusion technique for studying L-tryrosine transport into the ventricle
22James A. SchaeferM.S.1973Charles H. Jarboe, Ph.D.Some aspects of S-(-)-nicotine biochemorphology
21Yun-Lai ChanPh.D.1971Kee Chang Huang, M.D., Ph.D.Microperfusion and micropuncture studies of renal tubular transport of tryptophan derivatives
20Theresa S.T. ChenPh.D.1971Kee Chang Huang, M.D., Ph.D.Ion transport across the intestinal mucosa of fish
19Walter M. WilliamsPh.D.1970Kee Chang Huang, M.D., Ph.D.Structural specificity in the renal tubular transport of tryptophan derivatives
18George P. CastenPh.D.1969Thomas G. Scharff, Ph.D.Hexose-induced delay of hexose monophosphate fermentation in dialysed yeast extract
17Gloria D. SellsPh.D.1969Kee Chang Huang, M.D., Ph.D.Studies of the development of intestinal transport
16John A. NicholsonPh.D.1969Charles H. Jarboe, Ph.D.Pharmacological properties of viburnum
15Patrick E. BentleyPh.D.1968Peter K. Knoefel, M.D.Liberation of histamine as a mechanism of the toxic action of radiopaque diagnostic agents
14Kenneth L. BaileyPh.D.1968Peter K. Knoefel, M.D.Hippuric acid secretion in the mammalian kidney
13Karimullah Abd ZirviPh.D.1968Charles H. Jarboe, Ph.D.Centrally active imides and amides of certain cyclobutanecarboxylic acids
12Raymond L. WoosleyPh.D.1967Kee Chang Huang, M.D., Ph.D.Renal tubular transport of hexoses
11David N. JohnsonM.S.1966Richard P. Smith, Ph.D.The sympathetic innervation of the rabbit seminal vesicle
10Mahmoud OskouiPh.D.1965Peter K. Knoefel, M.D.Nephrotic action of a synthetic plastic material and some of its constituents
9Lin Min ChenM.S.1965Paul G. LeFevre, Ph.D.Reactions of red cell sugar transport system with non-transported analogues
8Robert L. MoffittPh.D.1964Thomas G. Scharff, Ph.D.Reinvestigation of certain aspects of fermentation in yeast extracts
7David LingM.S.1964Kee Chang Huang, M.D., Ph.D.Biliary excretion of organic acids
6Alan R. KolberPh.D.1964Paul G. LeFevre, Ph.D.Evidence for carrier-mediated transport of monosaccharides in the Ehrlich ascitis tumor cell
5Linda CohenM.S.1963Kee Chang Huang, M.D., Ph.D.Intestinal absorption of tryptophan and its derivatives
4Hubert J. WolfeM.S.1959Kee Chang Huang, M.D., Ph.D.The metabolism of the aminobenzoic acids in the adult and embryonic gallus domesticus
3James W. FisherPh.D.1958Peter K. Knoefel, M.D.The influence of the adrenocortical hormones on cobalt polycythemia
2Frederic E. ShafferM.S.1945A. James Miller, Ph.D. & Peter K. Knoefel, M.D.Studies on spinal anesthesia
1Herbert J. BrinkerM.S.1937George E. Wakerlin, M.D., Ph.D.

The effect of splenectomy on the differential cell count of the anterior pituitary in relation to post-splenectomy changes in the blood picture of the dog