Grant Awards

Members of the University of Louisville Department of Medicine are working hard in labs and clinics producing novel and groundbreaking research to benefit the health and well-being of the world community.

Researchers in Roman labUpdated January 26, 2024

Those efforts require the financial means to continue toward the goal of making the world a better place through breakthroughs in research.

While certain grant funding makes headlines, all is vital in the mission to advance the knowledge of clinicians and care-givers to better treat their patients and help them live their lives to the fullest.

We congratulate the members of our department whose hard work, dedication and curiosity make it possible to move forward in those quests.

(Source: UofL Office of Research & Innovation Metrics)


January 2024

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Matthew Cave

Gastroenterology

US Army Medical Rsch Acquisition Activit

Liver and Systemic Effects of Toxic Exposures

$1,368,092

 

Walter Watson, Ph.D.

Gastroenterology

US Army Medical Rsch Acquisition Activit

Liver and Systemic Effects of Toxic Exposures

$873,034


Previous Years

December 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Helen Collins, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Mechanisms Contributing to Pregnancy-Induced Cardiac Remodeling

$486,191

 

Michael Merchant, Ph.D.

Nephrology/
Hypertension

University of Pittsburgh

Novel Biomarkers for Post Liver Transplant NASH Fibrosis

$114,042


November 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Bradford Hill, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Role of the PEP Cycle in Cardiac Fibrosis

$2,269,628

 

Allan Ramirez, M.D.

Pulmonary

CareDX

SN-C-00016 - AlloSure Lung Assessment and Metagenomics Outcomes Study (ALAMO), Protocol Number SN-C-00016

$202,388.10


October 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Rochelle Holm, Ph.D.

Environmental Medicine

North Carolina State University/NSF

National Science Foundation International Research Experiences for Students (IRES) Track I: Filling the Gaps in WaSH Research Through Field-based Student Research Experiences in Malawi

$68,055

 

Chi Li, Ph.D.

Oncology/
Hematology

NIH National Institutes of Health

A Lung Cancer Vaccine Based on Exosomes of Induced Pluripotent Stem Cells

$402,401

 

Clara Sears, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Pre- and Postnatal Chemical Mixture Exposure, Adolescent Sleep Health, and Allostatic Load

$562,367

 

Banrida Wahlang, Ph.D.

Gastroenterology

US Army Medical Rsch Acquisition Activit

Acute and Sub-Chronic Exposures to Dioxin and Dioxin-Like Compounds in Liver Disease: the Role of Sex and Age

$774,620


September 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Daniel Nguyen

Environmental Medicine

NIH National Institutes of Health

Fibroblast TAK1 Signaling in Cardiac Fibrosis

$34,484

 

Levi Beverly, Ph.D.

Oncology/
Hematology

US Army Medical Rsch Acquisition Activi

Beyond CuATSM: Novel Copper Complexes for Improved ALS Therapy

$928,649

 

Shahab Ghafghazi, M.D.

Cardiovascular Medicine

Brigham and Women's Hospital

Enhancing Evidence Generation by Linking Randomized Clinical Research Clinical Trials (RCTs) to Real World Data (RWD) - Linkage of DELIVER Trial Participants to Their Observational Data

$9,250


August 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Roberto Bolli, M.D.

Cardiovascular Medicine

US Army Medical Rsch Acquisition Activit

A Phase IIA, Randomized, Double-Blind, Placebo-Controlled Study of Single or Repeated Intravenous Administration of UC-MSCs in Ischemic Cardiomyopathy (CATO)

$7,987,611


July 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Bradford Hill, Ph.D.

Environmental Medicine

American Heart Association

Physiologic Regulation of Metabolons in the Heart

$100,000

 

Shahab Ghafghazi, M.D.

Cardiovascular Medicine

American Heart Association

University of Louisville Cardiology: American Heart Association's Second Century of Science Clinical FellowResearch Education Grant

$12,000

 

Jason Chesney, M.D., Ph.D.

Oncology/
Hematology

KY Council on Postsecondary Education

FY24 Tobacco Settlement - Cancer Research

$3,125,000

 

 

 

KY Council on Postsecondary Education

FY24 Cancer Research Institute Matching

$2,053,850

 

Abigail Stocker, M.D.

Gastroenterology

Enterra Medical Inc

RESTING -Randomized Study of Enterra Programming with Nocturnal Cycling in Gastroparetics (CLN 001-PR-00755

$90,359


June 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Bradford Hill, Ph.D.

Environmental Medicine

American Heart Association

Physiologic Regulation of Metabolons in the Heart

$300,000

 

Brian Sansbury, Ph.D.

Environmental Medicine

Mount Sinai School of Medicine/NIH

Disturbed Crosstalk between Cholesterol Homeostatus and Inflammation Resolution in NASH

$33,115

 

 

 

Mount Sinai School of Medicine/NIH

EHD1-mediated Inflammation and Resolution in Atherosclerosis

$33,115

 

 

 

NIH National Institutes of Health

Role of Splenic Pro-Resolving Mediators During Exposure

$566,366

 

Madhavi Rane, Ph.D.

Nephrology/
Hypertension

Degrannin Therapeutics

Development of a Neutrophil Inhibitor to Treat ARDs

$51,417

 

Goetz Kloecker, M.D.

Oncology/
Hematology

PPD Development Inc

DELFI-L201 - Cancer Screening Assay using DELFI; A Clinical Validation Study in Lung Protocol: DELFI-20

$51,417

 

Tamer Mohamed, Ph.D.

Cardiovascular Medicine

Tenaya Therapeutics

Human Heart Slices Transduced with Adeno-Associated Virus (AAV) Human Gene Therapy Molecule TN-201

$39,330


May 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Theodore Smith, Ph.D.

Environmental Medicine

Robert Wood Johnson Foundation

Universal Basic Neighborhood: Reframing the Way We Address Health Equity by Using the Concept of Universal Basic Neighborhood to Expose and Treat Community Level Health Issues

$547,672

 

 

 

Louisville Metro Government

Lead Data Visualization

$29,640


April 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Rochelle Holm, Ph.D.

Environmental Medicine

Eurofins Scientific

Partnership to Support Multi-Pathogen Wastewater Surveillance Pilot in Malawi

$42,245


March 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Thomas Abell, Ph.D.

Gastroenterology

Mayo Clinic

Participation in the GpCRC Ancillary Study 28

$28,095


February 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Dinesh Kalra, M.D.

Cardiovascular Medicine

Canon Medical Systems USA

Assessment of Canon PIQE Software on Cardiac Computed Tomography Angiography

$64,416

 

Forest Arnold, D.O.

Infectious Diseases

Merck & Co., Inc.

A Multicenter Retrospective Study of High-Risk Patients Hospitalized with Breakthrough Infections of Severe COVID-19 in Louisville, Kentucky

$78,702


January 2023

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Helen Collins, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Mechanisms Contributing to Pregnancy-induced Cardiac Remodeling

$2,663,511

 

Forest Arnold, D.O.

Infectious Diseases

KY Cabinet for Health and Family Svs

FY 23 -Pre-Exposure Prophylaxis (PrEP) Care Coordinator Memoranda of Agreement MOA C3998

$225,885

 

Rochelle Holm, Ph.D.

Environmental Medicine

University of Kentucky Res. Fdn.

PIPP Phase I: Advancing Environmental Surveillance for Pandemic Prediction in Remote and Resource Poor Settings

$19,952

 

Anju Abhynkar, M.D.

Internal Medicine

Oatly US

Assessing Dietary Patterns and Implementing Cost-Effective Interventions to Encourage a Plant-Based Diet in an Underserved Urban Population

$5,000

December 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Brett Rossow, M.D.

Gastroenterology

CFF Cystic Fibrosis Foundation

Developing Innovative GastroEnterology Specialty Training (DIGEST) Program

$109,791


November 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Shirish Barve, Ph.D.

Gastroenertology

NIH National Institutes of Health

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

$702,843

 

Ryan Doster, M.D., Ph.D.

Infectious Diseases

NIH National Institutes of Health

Defining the Impact of Zinc on Streptococcus Agalactiae Biofilm and Colonization

$156,781


October 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Sanjay Srivastava, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Superfund-Admin Core: Environmental Exposure and Cardiometabolic Disease - Administrative Core

$2,188,987

 

Michael Merchant, Ph.D.

Nephrology/
Hypertension

University of Pittsburgh

Novel Biomarkers for Post Liver Transplant NASH Fibrosis

$114,042

 

Tamer Mohamed, Ph.D.

Cardiovascular Medicine

Merck & Co., Inc.

Model Evaluation and Evaluating the Efficacy of Acceleron Compounds in in vitro Cultured Human Heart Tissue Slices

$100,000

 

Theodore Smith, Ph.D.

Environmental Medicine

Louisville Metro Government

Metro Louisville Community Outreach - UDS/Envirome Contract FY2023

$15,000

 

Allan Ramirez, M.D.

Pulmonary

CFF Cystic Fibrosis Foundation

Outpatient Clinical Pharmacy Services: Award for a Pharmacist and Pharmacy Technician

$67,004

 

Levi Beverly, Ph.D.

Oncology/
Hematology

University of Kentucky Res. Fdn.

KYNETIC Subproject: Novel Copper Complexes as Cancer-Selective Therapeutics

$3,125


September 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Forest Arnold, D.O.

Infectious Diseases

HRSA Health Research & Services Admin

Ryan White HIV/A DS Program Part D Coordinated HIV Services and Access to Research for Women, Infants, Children, and Youth (WICY) Existing Geographic Service Areas

$545,786

 

Gerald Dryden, M.D.

Gastroenterology

University of Missouri

Food-Grade Bacterium as a Vehicle for Targeted Delivery of Immunotherapeutic Molecules into Colorectal Cancer

$14,679


August 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Sucheta Telang, M.D.

Oncology/
Hematology

US Department of Defense

Elucidating the Role of Glycolysis in the Growth and Metastasis of HER2+ Breast Cancer

$704,250

 

 

 

NIH National Institutes of Health

Investigating the Role of PFKFB4 in the Immune Regulation of Lung Cancer

$182,909

 

Xian-Liang Tang, Ph.D.

Cardiovascular Mediine

Rhode Island Hospital

Histone Deacetylase Inhibition: A Novel Approach to Cardioprotection

$46,800


July 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Igor Zelko, Ph.D.

Environmental Medicine

NIH National Institutes of Health

Benzene Exposure and Heart Failure

$430,375


June 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Irina Kirpich, Ph.D.

Gastroenterology

NIH National Institutes of Health

Role of Soluble Epoxide Hydrolase in Alcohol-Associated Liver Disease

$2,065,910

 

Banrida Wahlang, Ph.D.

Gastroenterology

NIH National Institutes of Health

Evaluating Mechanisms of Sex Differences in Environmentally-Induced Metabolic Diseases

$377,865


May 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Aruni Bhatnagar, Ph.D.

Environmental Medicine

Commonwealth of Kentucky

DOC COVID-19 Wastewater Program - Analysis

$209,176


April 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Alex Carll, Ph.D.

Environmental Medicine

National Institutes of Health

Systematic Identification of Cardiotoxic E-cigarette Flavorants

$3,570,934


March 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Steven Jones, Ph.D.

Environmental Medicine

National Institutes of Health

Extracellular Matrix Dynamics During Remodeling

$2,167,407


January 2022

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Steven Jones, Ph.D.

Environmental Medicine

National American Heart Association

LouisVille Undergraduate Training Program (LV-UP)

$164,964

 

T. Michael Sabo, Ph.D.

Oncology/
Hematology

National Institutes of Health

Linking the Conformational Energy Landscape to Enzymatic Function Through Functional Site Distant Mutations

$1,620,883

December 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Theodore Smith, Ph.D.

Environmental Medicine

Louisville/Jefferson Co Metro Government

Metro Louisville Community Outreach - UL UDS/Envirome Contract

$15,000


November 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Ashutosh Barve, M.D., Ph.D.

Gastroenterology

Vanderbilt University/NIH

Microbiome, Metabolites, and Alcohol in HIV to Reduce CVD (META HIV CVD)

$417,184

 

 

Gastroenterology

University of Florida/NIH

Interventions to Improve Alcohol-Related Comorbidities along the Gut-Brain axis in Persons with HIV Infection

$135,075

 

Theodore Smith, Ph.D.

Environmental Medicine

Rockefeller Foundation

Augmenting Traditional Clinical Genomic Surveillance of SARS-CoV-2 With Wastewater Data to Provide Valuable Complementary Insights for Public Health

$500,000


October 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Thomas Abell, M.D.

Gastroenterology

National Institutes of Health

Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping Technique

$450,020

 

Forest Arnold, D.O.

Infectious Diseases

Ky. Cabinet for Health & Family Services/CDC

Pre-Exposure Prophylaxis (PrEP) Care Coordinator

$225,885

 

Leila Gobejishvili, Ph.D.

Gastroenterology

National Institutes of Health

Phosphodiesterase 4 Mediated Pathogenic Mechanisms in Alcohol Associated Liver Disease

$1,778,856

 

Theodore Smith, Ph.D.

Environmental Medicine

Rockefeller Foundation

Precision Public Health Interventions Playbook: Wastewater and COVID Vaccinations

$500,000


September 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

David Powell, Ph.D.

Nephrology/
Hypertension

National Institutes of Health

ABIN1 Dysfunction in Lupus Nephritis

$2,932,372


August 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Daniel Conklin, Ph.D.

Environmental Medicine

National Institutes of Health

Cardiovascular Benefits of Inhaled Biogenic Volatile Organic Compounds

$429,688


July 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Vivek Sharma, M.D.

Oncology/
Hematology

University of North Carolina

Public Health Surveillance for the Prevention of Complications of Bleeding Disorders

$10,000

 

Vatsalya Vatsalya, Ph.D.

Gastroenterology

National Institutes of Health

Lactobacillus Rhamnosus: A Novel Probiotic Therapy for Treating Alcohol Use Disorder

$703,875


June 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jason Hellmann, Ph.D.

Environmental Medicine

New York University

Aspirin-triggered Specialized Pro-resolving Mediators in Increasing Weight and Atherosclerotic Cardiovascular Disease

$82,643

 

Craig McClain, M.D.

Gastroenterology

National Institutes of Health

The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ Injury

$6,976,092

 

Ruth Carrico, Ph.D.

Infectious Diseases

Louisville/Jefferson Co Metro Government

Testing Capacity Expansion

$150,000

 

Theodore Smith, Ph.D.

Environmental Medicine

Louisville/Jefferson Co Metro Government

COVID-19 Wastewater Sampling

$155,247


May 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Paula Bates, Ph.D.

Oncology/
Hematology

U.S. Economic Development Administration

The Pandemic-Related Product Acceleration & Responsive Entrepreneurship (PRePARE) Program

$750,000


April 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Craig McClain, M.D.

Gastroenterology

National Institutes of Health

University of Louisville Hepatobiology and Toxicology COBRE

$11,356,981


March 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Loretta Jophlin, M.D., Ph.D.

Gastroenterology

National Institutes of Health

Interaction of the Microtubule Cytoskeleton and Perilipin-2 Regulates Hepatic Lipid Droplets - a Potential Therapeutic Target for Fatty Liver Disease

$828,900


February 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Jewish Heritage Fund for Excellence

Investing in Faculty Recruitment: The JHFE Startup Supplement Program 2021-2022

$600,000

 

 

 

Jewish Heritage Fund for Excellence

2021 - JHFE Research Enhancement Grants at the University of Louisville Health Sciences Center

$600,000

 

Theodore Smith, Ph.D.

Environmental Medicine

University of Kentucky Res. Fdn.

Covid 19:Wastewater Surveillance to Prevent SARS Cov2 Infection in Nursing Homes

$23,844


January 2021

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Aruni Bhatnagar, Ph.D.

Environmental Medicine

Ky. Dept. of Corrections

Monitoring COVID-19 Infections in Correctional Facilities

$100,558

 

Ruth Carrico, Ph.D.

Infectious Diseases

Louisville/Jefferson Co Metro Government

Building Local Operational Capacity for COVID-19

$52,250

December 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Michael Brier, Ph.D.

Nephrology/
Hypertension

V.A. Medical Center

Michelle Barati IPA

$15,075.99

 

Jason Chesney, M.D., Ph.D.

Oncology/
Hematology

Ky. Council on Postsecondary Ed

FY21 & FY22 -Tobacco Settlement - UofL Cancer Research and Screening - Translational and Clinical Cancer Research Programs

$4,226,500

 

 

 

Ky. Council on Postsecondary Ed

FY21 & FY22 -Tobacco Settlement - UofL Cancer Research and Screening - New Faculty and Staff Recruitment

$1,429,600

 

 

 

Ky. Council on Postsecondary Ed

FY21 & FY22 - Tobacco Settlement - UofL Cancer Research and Screening - Clinical Trial and Cancer Screening Expansion

$1,220,000


November 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Ruth Carrico, Ph.D.

Infectious Diseases

Ky. Cabinet for Health & Family Service

COVID-19 Regional Training and Consultation Center

$3,454,660


October 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jerry Yu, Ph.D.

Pulmonary

V.A. Medical Center

Chao Lei IPA Agreement

$47,614.14

 

Chi Li, Ph.D.

Oncology/
Hematology

American Lung Association

Inhibiting Lung Adenocarcinoma Growth by Inducing Apoptosis Independent of Bcl-2 Proteins

$75,000

 

Sanjay Srivastava, Ph.D.

Environmental Medicine

University of Washington

Using Fortilin Inhibitors to Block Atherosclerosis

$101,942

 

Aruni Bhatnagar, Ph.D.

Environmental Medicine

Boston University

Rapidly Advancing Discovery to Arrest the Outbreak of Youth Vaping (VAPERACE)

$1,645,560


September 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Wenke Feng, Ph.D.

Gastroenterology

National Institutes of Health

Mechanisms of Probiotics in Alcoholic Liver Disease

$2,181,238

 

Matthew Cave, M.D.

Gastroenterology

National Institutes of Health

Exposome and Precision Medicine in NAFLD

$1,871,727


August 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Aruni Bhatnagar, Ph.D.

Environmental Medicine

Ky. Cabinet for Health & Family Services

Covid-19 Wastewater Pilot Program

$22,294

 

 

 

Lou. Metro Public Health & Wellness

Louisville Metro Government Co_Immunity TESTING PROJECT

$3,003,403

 

 

Michael Brier, Ph.D.

Nephrology/
Hypertension

V.A. Medical Center

Adam Gaweda IPA

$106,434.03

 

Wenke Feng, M.D.

Gastroenterology

National Institutes of Health

Probiotic and Intestinal miR194 Regulation of Bile Acid Metabolism in Alcoholic Liver Disease

$32,130

 

Michael Merchant, Ph.D.

Nephrology/
Hypertension

University of Pittsburgh

Biomarkers of Alcoholic Hepatitis

$102,451


July 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Howard Donninger, M.D.

Oncology/
Hematology

University of Kentucky Res. Fdn.

A Novel Anti-IL-6 Inhibitor as a New Immunotherapeutic for Uveitis

$50,000

 

Yoannis Imbert-Fernandez, Ph.D.

Oncology/
Hematology

National Institutes of Health

Targeting 6-Phosphofructo-2-Kinase to Increase Efficacy of CDK4/6 Inhibitors

$356,850

 

Tamer Mohamed, Ph.D.

Cardiovascular Medicine

University of Kentucky Res. Fdn.

An Innovative Therapeutic Approach to Treat Cardiomyopathy

$64,133

 

Jerry Yu, Ph.D.

Pulmonary

V.A. Medical Center

IPA Agreement - Lu Cai

$15,522

 

 

 

V.A. Medical Center

IPA Agreement - Igor Zelko

$4,774


June 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Robert Emmons, M.D.

Oncology/
Hematology

Ky. Cabinet for Health & Family Services

FY21 & FY22 - Good Manufacturing Practices Facility

$900,000


May 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Tamer Mohamed, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart Failure

$767,728


February 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Douglas Dean, Ph.D.

Oncology/
Hematology

National Institutes of Health

Blood Outer Retina Barrier Regulation

$594,101

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Jewish Heritage Fund for Excellence

JHFE Research Enhancement Grants

$600,000


January 2020

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Nationwide Children's Hospital

CUREGN 2.0 - Midwest Pediatric Nephrology Consortium - PCC

$13,726

 

Sanjay Srivastava, Ph.D.

Environmental Medicine

National Institutes of Health

Atherogenic Mechanisms of Electronic Nicotine Delivery Systems

$742,925

December 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Shirish Barve, Ph.D.

Gastroenterology

University of Florida

Health Outcomes and Cognitive Effects of Marijuana Use Among Persons Living With HIV/AIDS

$107,800


November 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jerry Yu, Ph.D.

Pulmonary

V.A. Medical Center

Zhong-bin Deng IPA Agreement

$35,227

 

Andrew DeFilippis, M.D.

Cardiovascular Medicine

University of Kentucky Res. Fdn.

Understanding the Role of Anti-Apolipoprotein A-I Antibodies in Atherosclerotic Cardiovascular Disease

$51,965

 

Shizuka Uchida, Ph.D.

Environmental Medicine

Brigham & Women's Hospital

Pro-Inflammatory Activation of Human Macrophages Regulated by lncRNAs

$32,098


August 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Bradford Hill, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Biosynthetic Pathways in Cardiac Remodeling

$763,757

 

Chi Li, Ph.D.

Oncology/
Hematology

U.S. Army Med Research Acq Activity

Identifying and Characterizing Neoantigens of an Embryonic Stem Cell-Based Lung Cancer Vaccine

$151,794

 

Jason Chesney, M.D., Ph.D.

Oncology/
Hematology

Susan G. Komen B. Cancer Fdn. Lou

Reducing Barriers to Breast Patient Care for Low Income and Rural Patients

$26,240


June 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Steven Jones, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Imaging and Physiology Core: High Frequency, High Resolution, Ultrasound Imaging System

$363,800


April 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Joongho Joh, Ph.D.

Oncology/
Hematology

Massachusetts General Hospital

The Role of the Immune System in Skin Homeostasis and Prevention of Skin Aging

$13,531


March 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Marcin Wysoczynski, Ph.D.

Cardiovascular Medicine

National Institutes of Health

The Role of Bioactive Lipids in CMC-induced Myocardial Repair

$385,000


February 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Sanjay Srivastava, Ph.D.

Cardiovascular Medicine

Children's Hospital Boston

Molecular Regulation of Atherosclerosis

$169,400


January 2019

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Aruni Bhatnagar, Ph.D.

Cardiovascular Medicine

National American Heart Association

ATRAC 2.0 - American Heart Association Tobacco Regulatory Science Center

$1,736,930

December 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jerry Yu, Ph.D.

Pulmonary

V.A. Medical Center

Xia Yu IPA Agreement

$78,281


November 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jason Chesney, M.D., Ph.D.

Oncology/
Hematology

Ky. Council on Postsecondary Ed

FY2019 & FY2020 - Cancer Research and Screening

$6,843,250

 

 

 

Ky. Council on Postsecondary Ed

FY2019 & FY2020 - Cancer Research Inst. Matching

$4,110,000

 

 

 

American Cancer Society

JGBCC M Krista Loyd Resource Center Transportation Fund

$15,000

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Jewish Heritage Fund

JHFE Research Enhancement Grants

$600,000

 

 

 

Jewish Heritage Fund

JHFE Research Recruitment

$600,000

 

 

Shirish Barve, Ph.D.

Gastroenterology

National Institutes of Health

Role of Gut Microbial Dysbiosis and Aging on HIV-Associated Neurocognitive and Brain Dysfunction

$779,748


October 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Eleanor Lederer, M.D.

Nephrology/
Hypertension

V.A. Medical Center

Michelle Barati IPA

$22,821

 

Craig McClain, M.D.

Gastroenterology

National Institutes of Health

Alcoholic Hepatitis Network 3/9 University of Louisville

$369,000


September 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jason Chesney, M.D., Ph.D.

Oncology/
Hematology

Ky. Cabinet for Health & Family Services

FY19 & FY20 Adult Hemophilia Clinics

$30,000

 

Paula Bates, Ph.D.

Oncology/
Hematology

National Science Foundation

PFI-RP: Development of Delivery Devices to Enable Cell Transformation or Preservation

$750,000

 

Petra Haberzettl, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Effects of Air Pollution on Stem Cell Health

$456,275

 

Jason Hellmann, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Exercise-enhanced Resolution of Inflammation

$462,462


August 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Paula Bates, Ph.D.

Oncology/
Hematology

U.S. Department of Defense

Combining Immunotherapy with Nanoparticles for Improved Kidney Cancer Outcomes

$115,500

 

Zhong-bin Deng, Ph.D.

Oncology/
Hematology

National Institutes of Health

Gut Extracellular Vesicles Promote Alcohol-Induced Liver Injury via TLR4-Regulated miRNAs

$221,375

 

 

 

National Institutes of Health

CSN8 Regulation of S1P-Enriched Extracellular Vesicles to Modulate NAFLD by Gut-Liver Axis

$415,800

 

Jerry Yu, Ph.D.

Pulmonary

V.A. Medical Center

IPA Agreement - Igor Zelko (Yu PULM-024-17S The Vagus Nerve in Lung Disease)

$112,036

 

 

 

V.A. Medical Center

IPA Agreement - Lu Cai (Yu PULM-024-17S The Vagus Nerve in Lung Disease)

$19,276


July 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Aruni Bhatnagar, Ph.D.

Cardiovascular Medicine

National Institutes of Health

COBRE - Center for Excellence in Diabetes and Obesity Research

$1,115,000

 

 

 

The Nature Conservancy

Green Heart Project

$2,000,000


June 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Levi Beverly, Ph.D.

Oncology/
Hematology

Kentucky Lung Cancer Research Program

Understanding the Role of Gamma Secretase and Ubiquilin in Antigen Processing, Interferon Signaling and Immunotherapy

$75,000

 

Ruth Carrico, Ph.D.

Infectious Diseases

Kentucky Department for Public Health

UofL Ebola Stimulus FY19

$170,000

 

Howard Donninger, Ph.D.

Oncology/
Hematology

Kentucky Lung Cancer Research Program

Overcoming Lung Cancer MDSC-mediated Immune Suppression by Targeting IL-6 Signaling

$75,000

 

Chi Li, Ph.D.

Oncology/
Hematology

Kentucky Lung Cancer Research Program

Inhibit Non-Small Cell Lung Cancer Growth by Targeting Paraoxonase 2

$75,000


March 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Joseph Moore IV, Ph.D.

Cardiovascular Medicine

National Institutes of Health

The Role of Cardiomyogenic Lineage Commitment in Cardiac Mesenchymal Cell-Mediated Extracellular Vesicle Signaling and Cardiac Repair

$385,000

 

Timothy O'Toole, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Endothelial Progenitor Cells and Particulate Air Pollution

$624,022


February 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Shirish Barve, Ph.D.

Gastroenterology

Vanderbilt University

1/2 Alcohol Associated Comorbidities and Microbiome Evaluation in HIV (ACME HIV)

$289,851


January 2018

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Ruth Carrico, Ph.D., RN

Infectious Diseases

Catholic Charities

Refugee Health Surveillance

$30,000

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Jewish Heritage Fund

Jewish Heritage Fund for Excellence Research Enhancement Grant

$347,385

November 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Shirish Barve, Ph.D.

Gastroenterology

National Institutes of Health

2/2 Alcohol Associated Comorbidities and Microbiome Evaluation in HIV (ACME HIV)

$673,788

 

Matthew Cave, M.D.

Gastroenterology

National Institutes of Health

Environmental Liver Disease

$550,876


October 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Roberto Bolli, M.D.

Cardiovascular Medicine

National Institutes of Health

Protection of Ischemic Myocardium

$2,774,979

 

Sanjay Srivastava, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Environmental Exposure and Cardiometabolic Disease - Admin Core

$1,335,021


September 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jonathan Chaires, Ph.D.

Oncology/
Hematology

National Institutes of Health

Targeting Nucleic Acids with an Integrated Virtual and Actual Screen

$355,395

 

Craig McClain, M.D.

Gastroenterology

VA Medical Center

IPA-Lanceta CSP#577 CONFIRM VA Cooperative Study

$35,587


August 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Sanjay Srivastava, Ph.D.

Cardiovascular Medicine

University of Texas Medical Branch

Using Fortilin Inhibitors to Block Atherosclerosis

$123,200

 

Children's Hospital Boston

Molecular Mechanisms Regulating Endothelial Dysfunction

$200,200

 

Jun Yan, Ph.D.

Oncology/
Hematology

National Psoriasis Foundation

Regulation of Innate Gammadelta T17 Cells in Skin Inflammation

$100,000


July 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Steven Jones, Ph.D.

Cardiovascular Medicine

National American Heart Association

Louisville Cardiovascular Mentorship Program: Developing Independent Cardiovascular Investigators

$60,000

 

Zhong-bin Deng, Ph.D.

Oncology/
Hematology

National Institutes of Health

Intestinal Epithelial Cells-Derived Exosomal miRNA's Regulate Liver Inflammation in Obesity

$231,000

 

Mariusz Ratajczak, M.D., Ph.D.

Oncology/
Hematology

National Institutes of Health

Novel Mechanisms Involving Complement Cascade in Stem Cell Trafficking

$346,500


June 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Nichola Garbett, Ph.D.

Oncology/
Hematology

Wake Forest University

Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer

$3,186

 

Wake Forest University

Stroma Targeted Theranostic Nanoparticles for Pancreatic Cancer

$5,461

 

Kavitha Yaddanapudi, M.D., Ph.D.

Oncology/
Hematology

Kentucky Lung Cancer Research Program

A Novel Immunotherapeutic Approach for the Treatment of Lung Cancer

$150,000

 

Mariusz Ratajczak, M.D., Ph.D.

Oncology/
Hematology

National Institutes of Health

Current Trends in Stem Cell Therapies

$128,751

 

Mark Rothstein, J.D.

Internal Medicine

National Institutes of Health

Addressing ELSI Issues in Unregulated Health Research Using Mobile Devices

$676,565


May 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Nichola Garbett, Ph.D.

Oncology/
Hematology

National Institutes of Health

Enhanced Diagnostic Assessment in Lupus Using Differential Scanning Calorimetry

$360,517

 

Petra Haberzettl, Ph.D.

Cardiovascular Medicine

National Institutes of Health

Air Pollution, Circadian Rhythm Disruption and Cardiometabolic Disease

$344,607


April 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Julio Ramirez, M.D.

Infectious Diseases

National Institutes of Health

Clinical and Translational Research in Pneumonia: Creating a Research Agenda for Today and Tomorrow

$5,000

 

John Trent, Ph.D.

Oncology/
Hematology

Kentucky Lung Cancer Research Program

Targeting the Human Telomere Complex in Lung Cancer

$150,000

 

Jun Yan, M.D., Ph.D.

Oncology/
Hematology

National Institutes of Health

Regulation of Dermal Gamma Delta T Cells by Pathogens/Microbial Commensals in Health and Psoriasis

$200,000

 


March 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Mark Pfiefer, M.D.

Internal Medicine

National Institutes of Health

Training in Interprofessional Education for Palliative Care in Oncology

$203,380

 

Craig McClain, M.D.

Gastroenterology

VA Medical Center

IPA - Mahanes - Dietary Fat & Alcoholic Liver Disease

$130,727

 

VA Medical Center

IPA - Warner - Dietary Fat & Alcoholic Liver Disease

$84,778

 

VA Medical Center

IPA - Mir-CSP#577 Confirm VA Cooperative Study

$123,854

 

 

Jon Klein, M.D., Ph.D.

Nephrology/
Hypertension

Nationwide Children's Hospital

Integrating Proteomics and Metabolomics to Understand Pediatric Glomerular Disease Pathophysiology and Prognosis

$250,784


February 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Jun Yan, Ph.D.

Oncology/
Hematology

National Institutes of Health

Transcriptional Regulation of Immunosupressive Macrophages by c-Maf in Cancer

$352,275


January 2017

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Monica Ann Shaw, M.D.

Internal Medicine

Commonwealth of Kentucky

Trover Rural Scholarships for Class 2017 and 2018

$1,406,000

 

Vincent La Russa, Ph.D.

Cardiovascular Medicine

Indiana University

Stem Cell Manufacturing to Support STL16101Q Champ Pilot Study

$69,900

December 2016

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Barbara Head, Ph.D., RN

Internal Medicine

Gordon and Betty Moore Foundation

Palliative and Hospice Social Worker Certification

$289,382


November 2016

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Lacey McNally, Ph.D.

Oncology/
Hematology

National Institutes of Health

Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer

$390,388


September 2016

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Barbara Head, Ph.D., RN

Internal Medicine

Hospice and Palliative Nurses Foundation

Work and Compassion Satisfaction, Burnout and Secondary Trauma Among Hospice and Palliative Nurses: Does Certification Make a Difference?

$14,926

 

Paula Bates, Ph.D.

Oncology/
Hematology

Jewish Heritage Fund

New Approaches to Overcome Malignant Brain Tumors

$112,670

 

Thomas Abell, M.D.

Gastroenterology

National Institutes of Health

University of Louisville's Clinical Center in Gastroparesis Clinical Research Consortium

$383,920

 

Ruth Carrico, Ph.D., RN

Infectious Diseases

Catholic Charities

Refugee Health Promotion

$19,244

 

Shirish Barve, Ph.D.

Gastroenterology

National Institutes of Health

Role of Gut Microbiome and DHA Deficiency in Alcohol Induced Neuroinflammation

$337,500


August 2016

 

Principal Investigator

Division

Sponsor

Title

Amount

 

Madhavi Rane, Ph.D.

Nephrology

Johns Hopkins University

Targeting Divergent Roles of Caspase 3 to Promote Endothelial Barrier Integrity

$30,800

 

Matthew Nystoriak, Ph.D.

Cardiovascular Medicine

American Heart Association - Great Rivers Affiliate

Compartmentalized Camp Signaling in Diabetic Vascular Dysfunction

$77,000

 

Jerry Yu, Ph.D.

Pulmonary

Pulmonary Fibrosis Foundation

The Vagus Nerve in Pulmonary Fibrosis

$50,000

 

Donald Miller, M.D., Ph.D.

Oncology/
Hematology

Kentucky Cabinet for Health & Family Services

Y17 Adult Hemophilia Clinics

$15,000

 

Kentucky Council on Postsecondary Education

Kentucky Lung Cancer Research Program - Administration

$3,718,600

 

Kentucky Council on Postsecondary Education

Tobacco Tax Funding-Cancer Research Institute Matching FY17-18

$4,110,000

 

Lacey McNalley, Ph.D.

Oncology/
Hematology

National Institutes of Health

Non-invasive Detection of Tumor Extracellular pH Using Multispectral Optoacoustic Tomography

$350,293


July 2016

 

Principal Investigator

Division

Sponsor

Title

Amount

 

A. Gregory Deam, M.D.

Cardiovascular Medicine

Boston Scientific Corproation

Clinical Cardiac Electrophysiology Fellowship Program

$25,000

 

Medtronic, Inc.

Clinical Cardiac Electrophysiology Fellowship Program

$30,000

 

Umair Gauhar, M.D.

Pulmonary

Veracyte, Inc.

Percepta R-1 :Respective Registry to Evaluate Percepta Bronchial Genomic Classifier Patient Data: The PERCEPTA Registry

$1,888

 

Veracyte, Inc.

Bronchial Sample Collection for a Novel Genomic Test-3

$68,380.37

 

Craig McClain, M.D.

Gastroenterology

National Institutes of Health

Novel Therapies In Alcoholic Hepatitis University of Louisville

$261,000

 

National Institutes of Health

Mechanisms for Alcohol Induced Gut Barrier Dysfunction in ALD

$322,818

 

National Institutes of Health

Hepatobiology and Toxicology COBRE - Administrative Core

$2,608,500

 

Donald Miller, M.D., Ph.D.

Oncology/
Hematology

National Institutes of Health

Molecular Targets CoBRE Phase III - Core A

$1,052,312

 

Sanjay Srivastava, Ph.D.

Cardiovascular Medicine

National American Heart Association

ATRAC -CORE A - Adminstration

$86,169

 

Aruni Bhatnagar, Ph.D.

Cardiovascular Medicine

National Institutes of Health

COBRE - Administrative Core

$2,250,000

 

Paula Peyrani, M.D.

Infectious Diseases

Health Resources and Services Administration

University of Louisville HIV Early Interventions Service (EIS Program)

$333,918

 

Kentucky Department for Public Health

FEDERAL FY17-18 KHCCP - UofL 550 Clinic

$2,026,382

 

Kentucky Department for Public Health

STATE FY17-18 KHCCP - UofL 550 Clinic

$1,198,680

 

Kavitha Yaddanapudi, Ph.D.

Oncology/
Hematology

National Institutes of Health

A Novel Vaccination Stratagem for Lung Cancer

$163,125

 

Shirish Barve, Ph.D.

Gastroenterology

National Institutes of Health

SAM Deficiency Mediated Epigenetic Mechanisms in Alcohol Induced Immunosuppression - Supplement

$100,000

 

Irina Kirpich, Ph.D.

Gastroenterology

National Institutes of Health

The Role of Dietary Unsaturated Fat and Inflammasome in Alcoholic Liver Disease

$346,500

 

Andrew Gibb

Cardiovascular Medicine

American Heart Association - Great Rivers Affiliate

Metabolic Regulation of Myocardial Adaptations to Exercise

$51,900

 

Xian-Liang Tang, M.D.

Cardiovascular Medicine

EndoProtech, Inc.

A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction

$69,253