Zhengzhi Xie, Ph.D.

Instructor in Medicine

E-mail 852-2477

Education and Training

Ph.D.: University of Arizona, Pharmaceutical Sciences
Postdoctoral Fellowship: University of Louisville, Center for Regulatory and Environmental Analytical Metabolomics

Featured Publications

  • Xie Z, Chen JY, Gao H, Keith RJ, Bhatnagar A, Lorkiewicz P, Srivastava S. Global Profiling of Urinary Mercapturic Acids Using Integrated Library-Guided Analysis. Environ Sci Technol. 2023 Jul 25;57(29):10563-10573. doi: 10.1021/acs.est.2c09554. Epub 2023 Jul 11. PMID: 37432892.
  • McGraw KE, Konkle SL, Riggs DW, Rai SN, DeJarnett N, Xie Z, Keith RJ, Oshunbade A, Hall ME, Shimbo D, Bhatnagar A. Exposure to Volatile Organic Compounds Is Associated with Hypertension in Black Adults: The Jackson Heart Study. Environ Res. 2023 Apr 15;223:115384. doi: 10.1016/j.envres.2023.115384. Epub 2023 Feb 14. PMID: 36796615; PMCID: PMC10134439.
  • Kumar R, Adhikari S, Driver EM, Smith T, Bhatnagar A, Lorkiewicz PK, Xie Z, Hoetker JD, Halden RU. Towards a novel application of wastewater-based epidemiology in population-wide assessment of exposure to volatile organic compounds. Sci Total Environ. 2022 Nov 1;845:157008. doi: 10.1016/j.scitotenv.2022.157008. Epub 2022 Jun 27. PMID: 35772546.
  • McGraw KE, Riggs DW, Rai S, Navas-Acien A, Xie Z, Lorkiewicz P, Lynch J, Zafar N, Krishnasamy S, Taylor KC, Conklin DJ, DeFilippis AP, Srivastava S, Bhatnagar A. Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction. Environ Res. 2021 May;196:110903. doi: 10.1016/j.envres.2021.110903. Epub 2021 Feb 24. PMID: 33636185; PMCID: PMC8119348.
  • Irfan AB, Arab C, DeFilippis AP, Lorkiewicz P, Keith RJ, Xie Z, Bhatnagar A, Carll AP. Smoking Accelerates Atrioventricular Conduction in Humans Concordant with Increased Dopamine Release. Cardiovasc Toxicol. 2021 Feb;21(2):169-178. doi: 10.1007/s12012-020-09610-5. Epub 2020 Oct 12. PMID: 33043409; PMCID: PMC7855806.
  • Lynch J, Jin L, Richardson A, Jagatheesan G, Lorkiewicz P, Xie Z, Theis WS, Shirk G, Malovichko MV, Bhatnagar A, Srivastava S, Conklin DJ. Acute and chronic vascular effects of inhaled crotonaldehyde in mice: Role of TRPA1. Toxicol Appl Pharmacol. 2020 Sep 1;402:115120. doi: 10.1016/j.taap.2020.115120. Epub 2020 Jul 4. PMID: 32634517; PMCID: PMC7485374.
  • Yeager R, Riggs DW, DeJarnett N, Srivastava S, Lorkiewicz P, Xie Z, Krivokhizhina T, Keith RJ, Srivastava S, Browning MHEM, Zafar N, Krishnasamy S, DeFilippis A, Turner J, Rai SN, Bhatnagar A. Association between residential greenness and exposure to volatile organic compounds. Sci Total Environ. 2020 Mar 10;707:135435. doi: 10.1016/j.scitotenv.2019.135435. Epub 2019 Nov 23. PMID: 31865083; PMCID: PMC7294698.
  • Carll AP, Salatini R, Pirela SV, Wang Y, Xie Z, Lorkiewicz P, Naeem N, Qian Y, Castranova V, Godleski JJ, Demokritou P. Inhalation of printer-emitted particles impairs cardiac conduction, hemodynamics, and autonomic regulation and induces arrhythmia and electrical remodeling in rats. Part Fibre Toxicol. 2020 Jan 29;17(1):7. doi: 10.1186/s12989-019-0335-z. PMID: 31996220; PMCID: PMC6990551.
  • Lorkiewicz P, Riggs DW, Keith RJ, Conklin DJ, Xie Z, Sutaria S, Lynch B, Srivastava S, Bhatnagar A. Comparison of Urinary Biomarkers of Exposure in Humans Using Electronic Cigarettes, Combustible Cigarettes, and Smokeless Tobacco. Nicotine Tob Res. 2019 Aug 19;21(9):1228-1238. doi: 10.1093/ntr/nty089. PMID: 29868926; PMCID: PMC6698950.
  • Abplanalp WT, Wickramasinghe NS, Sithu SD, Conklin DJ, Xie Z, Bhatnagar A, Srivastava S, O'Toole TE. Benzene Exposure Induces Insulin Resistance in Mice. Toxicol Sci. 2019 Feb 1;167(2):426-437. doi: 10.1093/toxsci/kfy252. PMID: 30346588; PMCID: PMC6358255.