Brian E. Sansbury, Ph.D.

Assistant Professor of Medicine


E-mail

Education and Training

Ph.D.: University of Louisville, Physiology and Biophysics
Postdoctoral Fellowships: University of Louisville, Cardiovascular Medicine; Brigham and Women's Hospital/Harvard Medical School, Physiologic Chemistry and Immunology


Featured Publications

  • Navarro-Corcuera A, Zhu Y, Ma F, Gupta N, Asplund H, Yuan F, Friedman S, Sansbury BE, Huang X, Cai B. Therapeutic Activity of Resolvin D1 (RvD1) in Murine MASH. bioRxiv [Preprint]. 2024 Apr 26:2024.04.22.590633. doi: 10.1101/2024.04.22.590633. PMID: 38712196; PMCID: PMC11071427.
  • Asplund H, Dreyer HH, Singhal R, Rouchka EC, O'Toole TE, Haberzettl P, Conklin DJ, Sansbury BE. Exposure to Fine Particulate Matter Air Pollution Disrupts Erythrocyte Turnover. Circ Res. 2024 Apr 26;134(9):1224-1227. doi: 10.1161/CIRCRESAHA.124.324411. Epub 2024 Apr 25. PMID: 38662858; PMCID: PMC11059477.
  • Berrueta L, Muñoz-Vergara D, Martin D, Thompson R, Sansbury BE, Spite M, Badger GJ, Langevin HM. Effect of stretching on inflammation in a subcutaneous carrageenan mouse model analyzed at single-cell resolution. J Cell Physiol. 2023 Dec;238(12):2778-2793. doi: 10.1002/jcp.31133. Epub 2023 Nov 1. PMID: 37909412; PMCID: PMC10773986.
  • Levy ES, Kim AS, Werlin E, Chen M, Sansbury BE, Spite M, Desai TA, Conte MS. Tissue factor targeting peptide enhances nanoparticle binding and delivery of a synthetic specialized pro-resolving lipid mediator to injured arteries. JVS Vasc Sci. 2023 Sep 26;4:100126. doi: 10.1016/j.jvssci.2023.100126. PMID: 38045567; PMCID: PMC10692706.
  • Sansbury BE, Nystoriak MA, Uchida S, Wysoczynski M, Moore JB 4th. Rigor Me This: What Are the Basic Criteria for a Rigorous, Transparent, and Reproducible Scientific Study? Front Cardiovasc Med. 2022 Jul 1;9:913612. doi: 10.3389/fcvm.2022.913612. PMID: 35845053; PMCID: PMC9283916.
  • Sugimoto S, Mena HA, Sansbury BE, Kobayashi S, Tsuji T, Wang CH, Yin X, Huang TL, Kusuyama J, Kodani SD, Darcy J, Profeta G, Pereira N, Tanzi RE, Zhang C, Serwold T, Kokkotou E, Goodyear LJ, Cypess AM, Leiria LO, Spite M, Tseng YH. Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation. Nat Metab. 2022 Jun;4(6):775-790. doi: 10.1038/s42255-022-00590-0. Epub 2022 Jun 27. PMID: 35760872; PMCID: PMC9792164.
  • Reeves AR, Sansbury BE, Pan M, Han X, Spite M, Greenberg AS. Correction: Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid-Derived Proinflammatory Lipid Mediators. J Immunol. 2022 Jun 1;208(11):2593. doi: 10.4049/jimmunol.2200133. Epub 2022 May 16. Erratum for: J Immunol. 2021 Dec 1;207(11):2744-2753. doi: 10.4049/jimmunol.2100393. PMID: 35577369.
  • Reeves AR, Sansbury BE, Pan M, Han X, Spite M, Greenberg AS. Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid-Derived Proinflammatory Lipid Mediators. J Immunol. 2021 Dec 1;207(11):2744-2753. doi: 10.4049/jimmunol.2100393. Epub 2021 Nov 1. Erratum in: J Immunol. 2022 Jun 1;208(11):2593. doi: 10.4049/jimmunol.2200133. PMID: 34725110; PMCID: PMC8802997.
  • Sadhu S, Decker C, Sansbury BE, Marinello M, Seyfried A, Howard J, Mori M, Hosseini Z, Arunachalam T, Finn AV, Lamar JM, Jourd'heuil D, Guo L, MacNamara KC, Spite M, Fredman G. Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation. J Immunol. 2021 Oct 1;207(7):1812-1823. doi: 10.4049/jimmunol.2100284. Epub 2021 Aug 30. PMID: 34462312; PMCID: PMC8555670.
  • Sansbury BE, Li X, Wong B, Riley CO, Shay AE, Nshimiyimana R, Petasis NA, Serhan CN, Spite M. PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds. Am J Pathol. 2021 Jun;191(6):1049-1063. doi: 10.1016/j.ajpath.2021.02.015. Epub 2021 Mar 6. PMID: 33689792; PMCID: PMC8176141.