A researcher whose work has substantially advanced the understanding of metals toxicology, John Pierce Wise, Sr., Ph.D., University Scholar and professor in the Department of Pharmacology and Toxicology, has received the Career Achievement Award from the Society of Toxicology (SOT) Metals Specialty Section.

The award, presented at the SOT’s annual meeting held last month in San Antonio, recognizes the outstanding achievement of a researcher, mentor and leader in the field of toxicology.

Wise was nominated by Max Costa, Ph.D., professor and chair of the Department of Environmental Medicine at NYU School of Medicine.

Costa says Wise’s influence in the education, training and mentorship of young scientists in the field of metals toxicology is “unequivocal.”

Wise has served as primary mentor for more than 40 doctoral and masters level students, while guiding nearly 90 undergraduate and  60 high school students in the field of biomedical and environmental research. He received the SOT Education award in 2016.

His research focuses on mechanistic toxicology with an emphasis on metal carcinogenesis and the “One Health” concept that human health, animal health and ecosystem health are intertwined and interdependent.

“Dr. Wise’s work has led to important advances in metal-induced genotoxicity, DNA repair and chromosome instability,” Costa said. “He is leading the effort to understand how metals can induce DNA breaks while suppressing their repair. In addition, he is a pioneer in the effort to understand how metals impact centrosome biology.”

The breadth of Wise’s work is exemplified through research in human cells as well as cells from other species including fish, whales, sea turtles and sea lions. In addition to bench science, Wise has lead field efforts to study the impact of the Gulf of Mexico oil crisis on resident whale species, the impact of metals on whales in the Gulf of Maine, and the conservation of sea turtles in Vieques, Puerto Rico.

The Society of Toxicology (SOT) is a professional and scholarly organization of more than 7,800 scientists from academic institutions, government and industry in the U.S. and abroad. The Metals Specialty Section is one of the organization’s 28 subgroups.

April 9, 2018