Amy A. Lemke, PhD, MS

Associate Professor of Pediatrics

Division of Clinical and Translational Research
Director, Community Engaged Research
Norton Children's Research Institute



Dr. Lemke is an Associate Professor of Pediatrics in the Division of Clinical and Translational Research. She received a PhD in Public Health from the University of Illinois at Chicago and also holds a MS degree in Genetic Counseling from the University of California - Berkeley. Dr. Lemke’s expertise is in precision medicine implementation evaluation and community engaged research strategies with underrepresented populations. She has extensive experience in qualitative, mixed-methods, and survey research to elicit key stakeholder perspectives on the impact and outcomes of genomic technologies in varied healthcare settings.


 Research Interests

  • Precision medicine innovation evaluation
  • Genomic health service delivery and outcomes
  • Ethical and social issues in genomic healthcare
  • Community engaged research in underrepresented groups
  • Health services implementation assessment

Current Projects and Grants

  • National Human Genome Research Institute. “Utility of Genome Sequencing in Community Care Contexts.” 2022 to 2025. This study explores the potential and actual utilities that children with undiagnosed genetic conditions might receive in community settings as a result of receiving a genomic diagnosis. Co-investigator.
  • National Human Genome Research Institute. “SouthSeq: DNA Sequencing for Newborn Nurseries in the South.” 2022 to 2022. This project examines the application of exome and genome sequencing technologies to identify the cause of genetic conditions in newborns and the return of results process by genetics and non-genetics specialists. Co-investigator.

Selected Publications and Manuscripts in Progress

Studies and projects related to stakeholder engagement and genomic research:

  1. Madrid S, Blum-Barnett E, Lemke AA, Pan V, Paolino V, McGlynn E, Burnett-Hartman A (2022). “A Gift to My Family for Their Future”: Attitudes About Genetic Research Participation. Public Health Genomics 25:98-107.       
  2. Lemke AA*, Esplin ED, Goldenberg, AJ, Gonzaga-Jauregui C, Hanchard N, Harris-Wai J, Ideozu JE, Isasi R, Landstrom AP, Prince AER, Turbitt E, Sabatello M. Schrier Vergano AD, Taylor MRG, Yu J-H, Brothers KB*, Garrison NA *(2022). Addressing Underrepresentation in Genomics Research through Community Engagement *Contributed equally as Co-Chairs of the ASHG Community Engagement Guidance Working Group. Am Jr Hum Genet (submitted)


 Studies related to precision medicine impacts and outcomes:

  1. Lemke AA, Hulick P, Hutten CG, Sereika A, Glaser N, Wake D. Dunnenberger M (2017). Primary Care Physician Experiences with Integrated Pharmacogenomic Testing in a Community Health System. Personalized Medicine 14(5): 389-400.
  2. Lemke AA, Hulick P, Sereika A, Yu K, Wang C, Glaser N, Wake D. Dunnenberger M (2018). Patient Perspectives following Pharmacogenomics Results Disclosure in an Integrated Health System. Pharmacogenomics 19(4): 321-331.
  3. Lemke AA, Thompson J, Hulick PJ, Sereika A, Johnson C, Oshman L, Dunnenberger HM (2020). Primary Care Physician Experiences Utilizing a Family Health History Tool with Electronic Health Record-Integrated Clinical Decision Support: An Implementation Process Evaluation. J Community Genet 11(3):339-350.
  4. Lemke AA, Dunnenberger HM, Thompson J, Johnson C, Kuchta K, Ilbawi N, Oshman L, Hulick PJ (2020). Primary Care Physician Experiences with Integrated Population-Scale Genetic Testing: A Mixed Methods Assessment. J Pers Med 10(4):165-172.
  5. Lemke AA, Amendola L, Thompson J, Dunnenberger HM, Wang C, Kuchta K, Dilzell-Yu K, Johnson C, Hulick P (2021). Patient-reported outcomes and experiences with population genetic testing offered through a primary care network. Genet Test Mol Biomarkers 25(2):152-160.
  6. Lemke AA, Choi S, Vinh Dang,Tommy Q. Dang, Joon-Ho Yu (2022). Assessing Vietnamese American Patient Perspectives on Genetic Testing in Primary Care: A Community Engaged Approach. Human Genetics and Genomics Advances (accepted)


Selected Conference Publications and Presentations

  1.  Potential Benefits and Risks of Direct Access Pharmacogenomics Testing: Patient Perspectives following Results Disclosure. Genomics and Society ELSI Congress. Farmington, CT. June, 2017.
  2. Where Could this Information End Up? Patient Views toward Privacy and Discrimination after Receiving Results from a Clinical Pre-emptive Genetic Testing Program. ELSI Congress. New York, New York. June, 2020.
  3. Delivering genomics digitally: Are we ready? American Society of Human Genetics. San Diego, CA. October, 2020.
  4. Patient-reported Outcomes and Experiences with Population Genetic Testing offered through a Primary Care Network. American Society of Human Genetics. San Diego, CA. October, 2020.
  5. Community Engaged Research in Precision Medicine: Navigating Steps along the Research Continuum in a Vietnamese American Community-based Project. Presented as part of a panel on Engagement with Historically Marginalized Communities: Methods, Positionality and ELSI in Precision Medicine Research. 5th ELSI Congress. June, 2022.
  6. Addressing Underrepresentation in Genomics Research through Community Engagement: Overview of ASHG Guidance Recommendations for Genomic Researchers. ASHG Summer Impact Panel. July, 2022.
  7. Assessing Vietnamese American Patient Views toward incorporating Genomics in Primary Care: A Community Engaged Research Approach. American Society of Human Genetics conference. October, 2022.