Brian Willliams, MD

Director of Brain Tumor Program, Neurosurgery Residency Program Co-Director, Associate Professor Neurosurgery

Department of Neurological Surgery


220 Abraham Flexner Way 502-588-2160

Make an appointment with Dr. Williams

Dr. Brian Williams is an Associate Professor in the Department of Neurosurgery at the University of Louisville School of Medicine. He joined the faculty in August 2016 after completing his residency in neurological surgery and specialty training in neurosurgical oncology and skull base surgery. Dr. Williams has special expertise in treating primary and metastatic tumors of the brain, spine, and skull base. In general, he seeks to treat each patient in the least invasive fashion possible. This includes using minimally invasive approaches such as laser ablation and endoscopic surgery whenever indicated.

Dr. Williams believes in patient-centered and collaborative medical treatment. He works closely with patients, family/caregivers and other healthcare providers to develop an individualized treatment plan for each specific circumstance. He works in multidisciplinary clinics for neuro-oncology and pituitary tumors.

His research interest focuses on understanding the stem cell biology of glioblastoma cancer-initiating cells and the role of hypoxia signaling in peritumoral edema from brain tumors. Dr. Williams also participates in collaborative research programs studying the clinical application of laser ablation as well as brain tumor banking.

In addition to his sub-specialty, Dr. Williams performs general neurosurgery procedures. He is licensed in Kentucky and Texas. To view Dr. Williams' CV, click here.

Dr. Williams was named to Louisville Magazine's Top Surgeons 2018 list in the Brain Surgery category.

Colleagues of Dr. Williams in related fields:

Brain Tumors

Pituitary Disorders

Recent Publications: