Ashwani K. Singal M.D., MS, FACG, FAASLD, AGAF

• Professor of Medicine
• Chair, Alcohol-Asociated Liver Disease Committee, CLD Foundation
• Chair, American Gastroenterology Association Council - Liver Biliary Section
• Advisor, AASLD SIG Task Force
• Chair, American Association for Study of Liver Diseases Special Interest Group on Alcohol-Associated Liver Disease (2019-2021)

UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments

Clinical Trials Unit MedCenter One
501 E. Broadway, Suite 210
Louisville, KY 40202

Clinical Trials Unit
401 E. Chestnut St., Suite 460
Louisville, KY 40202

Get To Know Dr. Singal

Editorial Appointments

Associate Editor

• Clinical Translational Gastroenterology (Journal of American College of Gastroenterology)
• Journal of Clinical Translational Hepatology (Journal of Chinese Medical Association)
• Digestive Liver Disease (Journal of Italian Gastroenterology Association)
• Journal of Clinical Experimental Hepatology (Journal of Indian Association for Study of Liver)

Section Editor

• Current Hepatology Reports

Guest Editor

• Translational Gastroenterology Hepatology (2019)
• Frontiers in Hepatology (2021)
• JCEH (2022)
• Metabolism Target Organ Damage (2022)
• Clinics in Liver Disease (2023-24)

Editorial Board

• Hepatology (leading liver journal of AASLD)
• Liver Transplantation (leading liver transplant journal of AASLD)
• Seminars Liver Disease
• Clinical Gastroenterology Hepatology (leading GI and Liver journal of AGA)
• JHEP Reports (one of the leading liver journals of European Association for Study of Liver)

Featured Publications

• Lee BP, Witkiewitz K, Mellinger J, Anania FA, Bataller R, Cotter TG, Curtis B, Dasarathy S, DeMartini KS, Diamond I, Diazgranados N, DiMartini AF, Falk DE, Fernandez AC, German MN, Kamath PS, Kidwell KM, Leggio L, Litten R, Louvet A, Lucey MR, McCaul ME, Sanyal AJ, Singal AK, Sussman NL, Terrault NA, Thursz MR, Verna EC, Radaeva S, Nagy LE, Mitchell MC. Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement. Nat Rev Gastroenterol Hepatol. 2024 Sep;21(9):626-645. doi: 10.1038/s41575-024-00936-x. Epub 2024 Jun 7. PMID: 38849555.
• Torres S, Hardesty JK, Barrios MK, Garcia C, José CF, Singal AK. Mitochondria and ALD: Pathogenic Role and Target for Therapy. Semin Liver Dis. 2024 Sep 24. doi: 10.1055/a-2421-5658. Epub ahead of print. PMID: 39317216.
• Thakurdesai A, Jha SK, Erinkitola I, Said A, Joshi T, Schwandt ML, Parajuli D, Singal AK, Kong M, Cave MC, Vatsalya V. The gut-immune-liver axis in patients with alcohol use disorder and clinically low serum zinc levels. Alcohol Clin Exp Res (Hoboken). 2024 Aug 2. doi: 10.1111/acer.15408. Epub ahead of print. PMID: 39095327.
• Singal AK, Shah VH, Malhi H. Emerging targets for therapy in ALD: Lessons from NASH. Hepatology. 2024 Jul 1;80(1):223-237. doi: 10.1097/HEP.0000000000000381. Epub 2023 Mar 21. PMID: 36938877; PMCID: PMC10511666.
• Maiwall R, Singh SP, Angeli P, Moreau R, Krag A, Singh V, Singal AK, Tan SS, Puri P, Mahtab M, Lau G, Ning Q, Sharma MK, Rao PN, Kapoor D, Gupta S, Duseja A, Wadhawan M, Jothimani D, Saigal S, Taneja S, Shukla A, Puri P, Govil D, Pandey G, Madan K, Eapen CE, Benjamin J, Chowdhury A, Singh S, Salao V, Yang JM, Hamid S, Shalimar, Jasuja S, Kulkarni AV, Niriella MA, Tevethia HV, Arora V, Mathur RP, Roy A, Jindal A, Saraf N, Verma N, De A, Choudhary NS, Mehtani R, Chand P, Rudra O, Sarin SK. APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure. Hepatol Int. 2024 Jun;18(3):833-869. doi: 10.1007/s12072-024-10650-0. Epub 2024 Apr 5. PMID: 38578541.
• Wong RJ, Yang Z, Cheung R, Singal AK, Do A, Ahmed A, Yeoh A. Impact of Longitudinal Alcohol Use Patterns on Long-Term Risk of Cirrhosis Among US Veterans With Steatotic Liver Disease. Gastroenterology. 2024 Jun;166(6):1156-1165.e4. doi: 10.1053/j.gastro.2024.02.032. Epub 2024 Feb 29. PMID: 38428619.
• Jalil S, Elfeki MA, Kiefer MK, Kuo YF, Singal AK. Waitlist and posttransplant outcomes of pregnancy-related acute liver failure in the United States. Liver Transpl. 2024 Jun 1;30(6):573-581. doi: 10.1097/LVT.0000000000000319. Epub 2023 Dec 18. PMID: 38108820.
• Dunn W, Li Y, Singal AK, Simonetto DA, Díaz LA, Idalsoaga F, Ayares G, Arnold J, Ayala-Valverde M, Perez D, Gomez J, Escarate R, Fuentes-López E, Ramirez-Cadiz C, Morales-Arraez D, Zhang W, Qian S, Ahn JC, Buryska S, Mehta H, Dunn N, Waleed M, Stefanescu H, Bumbu A, Horhat A, Attar B, Agrawal R, Cabezas J, Echavaría V, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Guerra-Salazar P, Skladaný L, Kubánek N, Prado V, Clemente-Sanchez A, Rincon D, Haider T, Chacko KR, Romero GA, Pollarsky FD, Restrepo JC, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jiménez C, Hudson D, García-Tsao G, Ortiz G, Abraldes JG, Kamath PS, Arrese M, Shah VH, Bataller R, Arab JP. An artificial intelligence-generated model predicts 90-day survival in alcohol-associated hepatitis: A global cohort study. Hepatology. 2024 Apr 12. doi: 10.1097/HEP.0000000000000883. Epub ahead of print. PMID: 38607809.
• Verma N, Mehtani R, Haiar JM, Pradhan P, Duseja A, Im GY, Singal AK. Clinical criteria accurately diagnose severe but not moderate alcohol-associated hepatitis: A systematic review and meta-analysis. Hepatol Commun. 2024 Mar 18;8(4):e0404. doi: 10.1097/HC9.0000000000000404. PMID: 38497934; PMCID: PMC10948131.
• Singal AK, Leggio L, DiMartini A. Alcohol use disorder in alcohol-associated liver disease: Two sides of the same coin. Liver Transpl. 2024 Feb 1;30(2):200-212. doi: 10.1097/LVT.0000000000000296. Epub 2023 Nov 8. PMID: 37934047.

Full list of publications from PubMed

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