Mohamed A. Saad, M.D., FCCP, FAASM

Mohamed Saad, M.D.

Mohamed A. Saad, M.D., FCCP, FAASM

UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 690
Louisville, KY 40202
502-852-5841 - Academic Office
502-588-4710 - Patient Appointments

Clinical Expertise
Critical Care (Sepsis, ARDS, Nutrition in Critically Ill Patients, Role of Ultra Sonography in the ICU); Sleep Medicine (SDB, Insomnia, Narcolepsy)

Board Certifications

  • American Board of Internal Medicine -
    Pulmonary Disease / Sleep Medicine / Critical Care Medicine
  • American Board of Sleep Medicine

Education and Training

  • Medical School: Alexandria University
  • Residency: Fairview Health System/ The Ohio State University
  • Fellowship: University of Louisville

Featured Publications

  • Duggal A, Conrad SA, Barrett NA, Saad M, Cheema T, Pannu S, Romero RS, Brochard L, Nava S, Ranieri VM, May A, Brodie D, Hill NS; VENT-AVOID Investigators. Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial - A Randomized Clinical Trial. Am J Respir Crit Care Med. 2024 Mar 1;209(5):529-542. doi: 10.1164/rccm.202311-2060OC. PMID: 38261630.
  • Tyagi SC, Pushpakumar S, Sen U, Mokshagundam SPL, Kalra DK, Saad MA, Singh M. COVID-19 Mimics Pulmonary Dysfunction in Muscular Dystrophy as a Post-Acute Syndrome in Patients. Int J Mol Sci. 2022 Dec 24;24(1):287. doi: 10.3390/ijms24010287. PMID: 36613731; PMCID: PMC9820572.
  • Moldoveanu B, Gearhart AM, Jalil BA, Saad M, Guardiola JJ. Pulmonary Aspergillosis: Spectrum of Disease. Am J Med Sci. 2021 Apr;361(4):411-419. doi: 10.1016/j.amjms.2020.12.009. Epub 2020 Dec 13. PMID: 33563417.
  • Akkanti B, Jagpal S, Darwish R, Saavedra Romero R, Scott LK, Dinh K, Hussain S, Radbel J, Saad MA, Enfield KB, Conrad SA. Physiologic Improvement in Respiratory Acidosis Using Extracorporeal Co2 Removal With Hemolung Respiratory Assist System in the Management of Severe Respiratory Failure From Coronavirus Disease 2019. Crit Care Explor. 2021 Mar 9;3(3):e0372. doi: 10.1097/CCE.0000000000000372. PMID: 33786448; PMCID: PMC7994071.
  • Lodise TP, Van Wart S, Sund ZM, Bressler AM, Khan A, Makley AT, Hamad Y, Salata RA, Silveira FP, Sims MD, Kabchi BA, Saad MA, Brown C, Oler RE Jr, Fowler V Jr, Wunderink RG. Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (ACUMIN). Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01809-20. doi: 10.1128/AAC.01809-20. PMID: 33168615; PMCID: PMC8092545.
  • Guardiola J, Saad M, Yu J. Hypertonic saline stimulates vagal afferents that respond to lung deflation. Am J Physiol Regul Integr Comp Physiol. 2019 Dec 1;317(6):R814-R817. doi: 10.1152/ajpregu.00064.2019. Epub 2019 Oct 9. PMID: 31596107; PMCID: PMC6962621.
  • Varajic B, Cavallazzi R, Mann J, Furmanek S, Guardiola J, Saad M. High versus low mean arterial pressures in hepatorenal syndrome: A randomized controlled pilot trial. J Crit Care. 2019 Aug;52:186-192. doi: 10.1016/j.jcrc.2019.04.006. Epub 2019 Apr 15. PMID: 31096099.
  • Kim RY, Ng AM, Persaud AK, Furmanek SP, Kothari YN, Price JD, Wiemken TL, Saad MA, Guardiola JJ, Cavallazzi RS. Antibiotic Timing and Outcomes in Sepsis. Am J Med Sci. 2018 Jun;355(6):524-529. doi: 10.1016/j.amjms.2018.02.007. Epub 2018 Feb 21. PMID: 29891035.
  • Jalil B, Thompson P, Cavallazzi R, Marik P, Mann J, El-Kersh K, Guardiola J, Saad M. Comparing Changes in Carotid Flow Time and Stroke Volume Induced by Passive Leg Raising. Am J Med Sci. 2018 Feb;355(2):168-173. doi: 10.1016/j.amjms.2017.09.006. Epub 2017 Sep 20. PMID: 29406045.
  • El-Kersh K, Jalil B, McClave SA, Cavallazzi R, Guardiola J, Guilkey K, Persaud AK, Furmanek SP, Guinn BE, Wiemken TL, Alhariri BC, Kellie SP, Saad M. Enteral nutrition as stress ulcer prophylaxis in critically ill patients: A randomized controlled exploratory study. J Crit Care. 2018 Feb;43:108-113. doi: 10.1016/j.jcrc.2017.08.036. Epub 2017 Aug 26. PMID: 28865339.