Elizabeth C. Riley M.D., FACP

Elizabeth C. Riley M.D.

Elizabeth C. Riley M.D., FACP

  • Professor of Medicine
  • Deputy Director of Health Affairs, UofL Health - Brown Cancer Center
  • Section Chief, Medical Oncology and Benign Hematology
  • Director, Breast Cancer Multidisciplinary Clinic
UofL Health - Brown Cancer Center
529 South Jackson Street
Louisville, KY 40202

502-852-2522 - Academic Office
502-562-4370 - Patient Appointments


Clinical Expertise
Medical Oncology-Breast; Hematology


Board Certifications

  • American Board of Internal Medicine -
    Medical Oncology

Education and Training

  • Medical School: University of Louisville
  • Residency: Beth Israel Deaconess Medical Center - Harvard Medical School
  • Fellowship: Beth Israel Deaconess Medical Center - Harvard Medical School

Get To Know Dr. Riley


Featured Publications

  • Mayer EL, Ren Y, Wagle N, Mahtani R, Ma C, DeMichele A, Cristofanilli M, Meisel J, Miller KD, Abdou Y, Riley EC, Qamar R, Sharma P, Reid S, Sinclair N, Faggen M, Block CC, Ko N, Partridge AH, Chen WY, DeMeo M, Attaya V, Okpoebo A, Alberti J, Liu Y, Gauthier E, Burstein HJ, Regan MM, Tolaney SM. PACE: A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab After Progression on Cyclin-Dependent Kinase 4/6 Inhibitor and Aromatase Inhibitor for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor-Negative Metastatic Breast Cancer. J Clin Oncol. 2024 Jun 10;42(17):2050-2060. doi: 10.1200/JCO.23.01940. Epub 2024 Mar 21. PMID: 38513188.
  • Reshko LB, Pan J, Rai SN, Ajkay N, Dragun A, Roberts TL, Riley EC, Quillo AR, Scoggins CR, McMasters KM, Eldredge-Hindy H. Final Analysis of a Phase 2 Trial of Once Weekly Hypofractionated Whole Breast Irradiation for Early-Stage Breast Cancer. Int J Radiat Oncol Biol Phys. 2022 Jan 1;112(1):56-65. doi: 10.1016/j.ijrobp.2021.06.026. Epub 2021 Oct 25. PMID: 34710520.
  • Eldredge-Hindy H, Pan J, Rai SN, Reshko LB, Dragun A, Riley EC, McMasters KM, Ajkay N. A Phase II Trial of Once Weekly Hypofractionated Breast Irradiation for Early Stage Breast Cancer. Ann Surg Oncol. 2021 Oct;28(11):5880-5892. doi: 10.1245/s10434-021-09777-3. Epub 2021 Mar 18. PMID: 33738712.
  • Eldredge-Hindy H, Gaskins J, Dragun A, Roberts TL, Riley EC, McMasters KM, Ajkay N. Patient-Reported Outcomes and Cosmesis After Once-Weekly Hypofractionated Breast Irradiation in Medically Underserved Patients. Int J Radiat Oncol Biol Phys. 2020 Aug 1;107(5):934-942. doi: 10.1016/j.ijrobp.2020.04.041. Epub 2020 May 6. PMID: 32387804.
  • Bhandari S, Kumar R, Tripathi P, Riley E. Apple-core lesion. Curr Probl Cancer. 2019 Dec;43(6):100475. doi: 10.1016/j.currproblcancer.2019.04.001. Epub 2019 May 3. PMID: 31079837.
  • Bhandari S, Ngo P, Kute B, Mandadi M, Pitman WA, Wu X, Lloyd S, Brown MC, Rai SN, Jain D, Riley EC. Adherence to anti-estrogen therapy in women with hormone receptor-positive breast cancer utilizing bubble packaging: a pilot study. Breast Cancer Res Treat. 2019 Sep;177(2):395-399. doi: 10.1007/s10549-019-05308-7. Epub 2019 Jun 6. PMID: 31172406.
  • Breaux A, Turner B, Wu X, Rai SN, Riley EC, Mandadi M, Sanders MA. Impact of 21-Gene Expression Assay on Staging Estrogen Receptor-Positive HER2-Negative Breast Cancer. Clin Breast Cancer. 2019 Feb;19(1):e261-e269. doi: 10.1016/j.clbc.2018.10.005. Epub 2018 Oct 29. PMID: 30509870.
  • Dragun AE, Ajkay NJ, Riley EC, Roberts TL, Pan J, Rai SN, Jain D, Quillo AR, Scoggins CR, McMasters KM, Woo SY. First Results of a Phase 2 Trial of Once-Weekly Hypofractionated Breast Irradiation (WHBI) for Early-Stage Breast Cancer. Int J Radiat Oncol Biol Phys. 2017 Jul 1;98(3):595-602. doi: 10.1016/j.ijrobp.2017.01.212. PMID: 28581400.
  • Panchabhai TS, Patil PD, Riley EC, Mitchell CK. When the picture is fragmented: Vitamin B12 deficiency masquerading as thrombotic thrombocytopenic purpura. Int J Crit Illn Inj Sci. 2016 Apr-Jun;6(2):89-92. doi: 10.4103/2229-5151.183026. PMID: 27308258; PMCID: PMC4901834.
  • Boone SD, Baumgartner KB, Baumgartner RN, Connor AE, John EM, Giuliano AR, Hines LM, Rai SN, Riley EC, Pinkston CM, Wolff RK, Slattery ML. Active and passive cigarette smoking and mortality among Hispanic and non-Hispanic white women diagnosed with invasive breast cancer. Ann Epidemiol. 2015 Nov;25(11):824-31. doi: 10.1016/j.annepidem.2015.08.007. Epub 2015 Aug 28. PMID: 26387598; PMCID: PMC4609618.