Loretta L. Jophlin, M.D., Ph.D.

Loretta L. Jophlin, M.D., Ph.D.

Loretta L. Jophlin, M.D., Ph.D.

  • Assistant Professor of Medicine
  • Medical Director, Liver Transplant Program
UofL Healthcare Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Transplant Hepatology; Alcohol Associated Liver Disease


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Gastroenterology / Transplant Hepatology

Education and Training

  • Medical School: Medical University of South Carolina
  • Residency: Mount Sinai Hospital
  • Fellowships: Medical University of South Carolina (Gastroenterology); Mayo Clinic (Transplant Hepatology)
  • Ph.D.: Medical University of South Carolina

Get To Know Dr. Jophlin


Featured Publications

  • Jophlin L, Liu TY, McClain CJ. Nutritional deficiencies in alcohol use disorder/alcohol-associated liver disease. Curr Opin Gastroenterol. 2024 Mar 1;40(2):112-117. doi: 10.1097/MOG.0000000000000999. Epub 2024 Jan 2. PMID: 38193343.
  • Jophlin LL, Singal AK, Bataller R, Wong RJ, Sauer BG, Terrault NA, Shah VH. ACG Clinical Guideline: Alcohol-Associated Liver Disease. Am J Gastroenterol. 2024 Jan 1;119(1):30-54. doi: 10.14309/ajg.0000000000002572. Epub 2023 Sep 1. PMID: 38174913; PMCID: PMC11040545.
  • Condon S, Jophlin LL. Past, Present, and Future Therapies for Alcohol-associated Hepatitis. Clin Ther. 2023 Dec;45(12):1171-1176. doi: 10.1016/j.clinthera.2023.10.013. Epub 2023 Nov 18. PMID: 37980219; PMCID: PMC10842010.
  • Groswald AM, Gripshover TC, Watson WH, Wahlang B, Luo J, Jophlin LL, Cave MC. Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver. Metabolites. 2023 Aug 1;13(8):901. doi: 10.3390/metabo13080901. PMID: 37623845; PMCID: PMC10456691.
  • Winrich E, Belur AD, Shine A, Jophlin LL. Takotsubo cardiomyopathy following liver transplantation and COVID-19 infection. Proc (Bayl Univ Med Cent). 2022 Aug 23;36(1):99-100. doi: 10.1080/08998280.2022.2114069. PMID: 36578602; PMCID: PMC9762796.
  • Sagaram M, Parthasarathy R, Condon SL, Closson CF, Kong M, Schwandt ML, Jophlin LL, Feng W, Barve AJ, Vatsalya V. Theragnostic Efficacy of K18 Response in Alcohol Use Disorder with Clinically Significant Fibrosis Using Gut-Liver Axis. Int J Mol Sci. 2022 May 23;23(10):5852. doi: 10.3390/ijms23105852. PMID: 35628661; PMCID: PMC9143806.
  • Faulkner CS, White CM, Manatsathit W, Lamb B, Vatsalya V, McClain CJ, Jophlin LL. Positive blood phosphatidylethanol concentration is associated with unfavorable waitlist-related outcomes for patients medically appropriate for liver transplantation. Alcohol Clin Exp Res. 2022 Apr;46(4):581-588. doi: 10.1111/acer.14786. Epub 2022 Mar 15. PMID: 35102553; PMCID: PMC9150771.
  • Jophlin LL, Hartley CP, Katzka DA. Ectopic Esophageal Sebaceous Glands. Clin Gastroenterol Hepatol. 2022 Apr;20(4):e647. doi: 10.1016/j.cgh.2020.11.034. Epub 2020 Dec 3. PMID: 33279776.
  • Jophlin L, Singal AK. Liver Biopsy in Patients With Alcohol-Associated Liver Disease With Acute-on-Chronic Liver Failure. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):544-550. doi: 10.1016/j.jceh.2021.08.009. Epub 2021 Aug 14. PMID: 35535109; PMCID: PMC9077173.
  • Im GY, Mellinger JL, Winters A, Aby ES, Lominadze Z, Rice J, Lucey MR, Arab JP, Goel A, Jophlin LL, Sherman CB, Parker R, Chen PH, Devuni D, Sidhu S, Dunn W, Szabo G, Singal AK, Shah VH. Provider Attitudes and Practices for Alcohol Screening, Treatment, and Education in Patients With Liver Disease: A Survey From the American Association for the Study of Liver Diseases Alcohol-Associated Liver Disease Special Interest Group. Clin Gastroenterol Hepatol. 2021 Nov;19(11):2407-2416.e8. doi: 10.1016/j.cgh.2020.10.026. Epub 2020 Oct 16. PMID: 33069880; PMCID: PMC8291372.