Alfred A. Jacobs Jr., M.D., Ph.D.
Alfred A. Jacobs Jr., M.D., Ph.D.
- Associate Professor of Medicine
401 East Chestnut Street, Ste. 690
Louisville, KY 40202
502-852-5757 - Academic Office
502-588-4710 - Patient Appointments
Clinical Expertise
Nephrology; Hemodialysis; Peritoneal Dialysis; Acute Therapies
Board Certifications
- American Board of Internal Medicine -
Internal Medicine - American Board of Nephrology
Education and Training
- Medical School: University of Louisville
- Residency: University of Louisville Hospital
- Fellowship: University of Louisville
Featured Publications
- Gaweda AE, Jacobs AA, Aronoff GR, Brier ME. Individualized anemia management in a dialysis facility - long-term utility as a single-center quality improvement experience . Clin Nephrol. 2018 Oct;90(4):276-285. doi: 10.5414/CN109499. PMID: 30049300; PMCID: PMC6350237.
- Gaweda AE, Aronoff GR, Jacobs AA, Rai SN, Brier ME. Individualized anemia management reduces hemoglobin variability in hemodialysis patients. J Am Soc Nephrol. 2014 Jan;25(1):159-66. doi: 10.1681/ASN.2013010089. Epub 2013 Sep 12. PMID: 24029429; PMCID: PMC3871773.
- Gaweda AE, Nathanson BH, Jacobs AA, Aronoff GR, Germain MJ, Brier ME. Determining optimum hemoglobin sampling for anemia management from every-treatment data. Clin J Am Soc Nephrol. 2010 Nov;5(11):1939-45. doi: 10.2215/CJN.03540410. Epub 2010 Jul 29. PMID: 20671221; PMCID: PMC3001763.
- Brier ME, Gaweda AE, Dailey A, Aronoff GR, Jacobs AA. Randomized trial of model predictive control for improved anemia management. Clin J Am Soc Nephrol. 2010 May;5(5):814-20. doi: 10.2215/CJN.07181009. Epub 2010 Feb 25. PMID: 20185598; PMCID: PMC2863987.
- Gaweda AE, Jacobs AA, Aronoff GR, Brier ME. Model predictive control of erythropoietin administration in the anemia of ESRD. Am J Kidney Dis. 2008 Jan;51(1):71-9. doi: 10.1053/j.ajkd.2007.10.003. PMID: 18155535.
- Gaweda AE, Muezzinoglu MK, Aronoff GR, Jacobs AA, Zurada JM, Brier ME. Using clinical information in goal-oriented learning. IEEE Eng Med Biol Mag. 2007 Mar- Apr;26(2):27-36. doi: 10.1109/memb.2007.335580. PMID: 17441606.
- Gaweda AE, Muezzinoglu MK, Jacobs AA, Aronoff GR, Brier ME. Model predictive control with reinforcement learning for drug delivery in renal anemia management. Conf Proc IEEE Eng Med Biol Soc. 2006;2006:5177-80. doi: 10.1109/IEMBS.2006.260685. PMID: 17946288.
- Gaweda AE, Muezzinoglu MK, Aronoff GR, Jacobs AA, Zurada JM, Brier ME. Individualization of pharmacological anemia management using reinforcement learning. Neural Netw. 2005 Jun-Jul;18(5-6):826-34. doi: 10.1016/j.neunet.2005.06.020. PMID: 16109475.
- Gaweda AE, Jacobs AA, Brier ME, Zurada JM. Pharmacodynamic population analysis in chronic renal failure using artificial neural networks--a comparative study. Neural Netw. 2003 Jun-Jul;16(5-6):841-5. doi: 10.1016/S0893-6080(03)00084-4. PMID: 12850042.