Education and Training

B.A.: Emory University (Chemistry)
Ph.D.: University of Kentucky (Toxicology)

Research Interests

• Oxidative stress and redox signaling
• Mechanistic toxicology
• Alcoholic and nonalcoholic fatty liver disease

Featured Publications

• Zhao J, Adiele N, Gomes D, Malovichko M, Conklin DJ, Ekuban A, Luo J, Gripshover T, Watson WH, Banerjee M, Smith ML, Rouchka EC, Xu R, Zhang X, Gondim DD, Cave MC, O'Toole TE. Obesogenic polystyrene microplastic exposures disrupt the gut-liver-adipose axis. Toxicol Sci. 2024 Mar 26;198(2):210-220. doi: 10.1093/toxsci/kfae013. PMID: 38291899; PMCID: PMC10964747.
• Luo J, Watson WH, Gripshover TC, Qaissi Z, Wahlang B. Sex-specific effects of acute chlordane exposure in the context of steatotic liver disease, energy metabolism and endocrine disruption. Food Chem Toxicol. 2023 Oct;180:114024. doi: 10.1016/j.fct.2023.114024. Epub 2023 Sep 4. PMID: 37666290; PMCID: PMC10617492.
• Minooei F, Gilbert NM, Zhang L, Sarah NeCamp M, Mahmoud MY, Kyser AJ, Tyo KM, Watson WH, Patwardhan R, Lewis WG, Frieboes HB, Lewis AL, Steinbach-Rankins JM. Rapid-dissolving electrospun nanofibers for intra-vaginal antibiotic or probiotic delivery. Eur J Pharm Biopharm. 2023 Sep;190:81-93. doi: 10.1016/j.ejpb.2023.07.009. Epub 2023 Jul 19. PMID: 37479065; PMCID: PMC10530173.
• Groswald AM, Gripshover TC, Watson WH, Wahlang B, Luo J, Jophlin LL, Cave MC. Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver. Metabolites. 2023 Aug 1;13(8):901. doi: 10.3390/metabo13080901. PMID: 37623845; PMCID: PMC10456691.
• Bolatimi OE, Head KZ, Luo J, Gripshover TC, Lin Q, Adiele NV, Watson WH, Wilkerson C, Cai L, Cave MC, Young JL. Can Zinc Supplementation Attenuate High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease? Int J Mol Sci. 2023 Jan 16;24(2):1763. doi: 10.3390/ijms24021763. PMID: 36675277; PMCID: PMC9864360.
• Watson WH, Ritzenthaler JD, Torres-Gonzalez E, Arteel GE, Roman J. Mice lacking α4 nicotinic acetylcholine receptors are protected against alcohol-associated liver injury. Alcohol Clin Exp Res. 2022 Aug;46(8):1371-1383. doi: 10.1111/acer.14893. Epub 2022 Jul 3. PMID: 35723023; PMCID: PMC9427714.
• Ritzenthaler JD, Torres-Gonzalez E, Zheng Y, Zelko IN, van Berkel V, Nunley DR, Kidane B, Halayko AJ, Summer R, Watson WH, Roman J. The profibrotic and senescence phenotype of old lung fibroblasts is reversed or ameliorated by genetic and pharmacological manipulation of Slc7a11 expression. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L449-L461. doi: 10.1152/ajplung.00593.2020. Epub 2022 Jan 5. PMID: 34984918; PMCID: PMC8917919.
• Zelko IN, Taylor BS, Das TP, Watson WH, Sithu ID, Wahlang B, Malovichko MV, Cave MC, Srivastava S. Effect of vinyl chloride exposure on cardiometabolic toxicity. Environ Toxicol. 2022 Feb;37(2):245-255. doi: 10.1002/tox.23394. Epub 2021 Oct 30. PMID: 34717031; PMCID: PMC8724461.
• Bushau-Sprinkle AM, Barati MT, Zheng Y, Watson WH, Gagnon KB, Khundmiri SJ, Kitterman KT, Clark BJ, Siskind LJ, Doll MA, Brier ME, Coventry S, Lederer ED. Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics. Antioxidants (Basel). 2021 Jun 28;10(7):1036. doi: 10.3390/antiox10071036. PMID: 34203453; PMCID: PMC8300832.
• Zhou B, Gentry A, Xu Q, Young JL, Yan X, Pagidas K, Yang Y, Watson WH, Kong M, Cai L, Freedman JH. Effects of cadmium and high-fat diet on essential metal concentration in the mouse testis. Toxicol Rep. 2021 Mar 20;8:718-723. doi: 10.1016/j.toxrep.2021.03.016. PMID: 33889501; PMCID: PMC8047427.