Ming Song, M.D., Ph.D.

Assistant Professor of Medicine


502-852-1370 E-mail

Education and Training

M.D.: Binzhou Medical College
M.S.: Capital University of Medical Sciences
Ph.D.: Capital University of Medical Sciences


Research Interests

  • Fructose and Fatty Liver
  • Spinal Cord Injury and Liver Disease
  • Nuclear Hormones and Liver Disease

Featured Publications

  • Xu M, Li M, Benz F, Merchant M, McClain CJ, Song M. Ileum Proteomics Identifies Distinct Pathways Associated with Different Dietary Doses of Copper-Fructose Interactions: Implications for the Gut-Liver Axis and MASLD. Nutrients. 2024 Jun 29;16(13):2083. doi: 10.3390/nu16132083. PMID: 38999831; PMCID: PMC11242941.
  • Ghooray DT, Xu M, Shi H, McClain CJ, Song M. Hepatocyte-Specific <i>Fads1</i> Overexpression Attenuates Western Diet-Induced Metabolic Phenotypes in a Rat Model. Int J Mol Sci. 2024 Apr 29;25(9):4836. doi: 10.3390/ijms25094836. PMID: 38732052; PMCID: PMC11084797.
  • Cai J, Song M, Li M, Merchant M, Benz F, McClain C, Klein J. Site-Specific Identification of Protein S-Acylation by IodoTMT0 Labeling and Immobilized Anti-TMT Antibody Resin Enrichment. J Proteome Res. 2024 Feb 2;23(2):673-683. doi: 10.1021/acs.jproteome.3c00525. Epub 2023 Dec 29. PMID: 38157263.
  • McClain CJ, Kirpich I, Song M, Vatsalya V. Keratin 18-M65: A biomarker for early-stage alcohol-associated liver disease. Alcohol Clin Exp Res (Hoboken). 2023 Jul;47(7):1257-1260. doi: 10.1111/acer.15117. Epub 2023 Jun 14. PMID: 37526591.
  • Cohen CC, Huneault H, Accardi CJ, Jones DP, Liu K, Maner-Smith KM, Song M, Welsh JA, Ugalde-Nicalo PA, Schwimmer JB, Vos MB. Metabolome × Microbiome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys. Metabolites. 2023 Mar 8;13(3):401. doi: 10.3390/metabo13030401. PMID: 36984841; PMCID: PMC10053986.
  • Shi H, Prough RA, McClain CJ, Song M. Different Types of Dietary Fat and Fructose Interactions Result in Distinct Metabolic Phenotypes in Male Mice. J Nutr Biochem. 2023 Jan;111:109189. doi: 10.1016/j.jnutbio.2022.109189. Epub 2022 Oct 19. PMID: 36272691.
  • Song M. Response to Letter to the Editor by Scarano-Pereira et al.: Response to: Recent advances in the mechanisms underlying the beneficial effects of bariatric and metabolic surgery. Surg Obes Relat Dis. 2022 Feb;18(2):298. doi: 10.1016/j.soard.2021.11.008. Epub 2021 Nov 11. PMID: 34866015.
  • Song M. Comment on: Toll-like receptor 4 and MyD88 are required for gastric bypass-induced metabolic effects. Surg Obes Relat Dis. 2021 Dec;17(12):2006-2008. doi: 10.1016/j.soard.2021.08.019. Epub 2021 Aug 30. PMID: 34538571.
  • Rai SN, Qian C, Pan J, Rai JP, Song M, Bagaitkar J, Merchant M, Cave M, Egilmez NK, McClain CJ. Microbiome data analysis with applications to pre-clinical studies using QIIME2: Statistical considerations. Genes Dis. 2019 Dec 24;8(2):215-223. doi: 10.1016/j.gendis.2019.12.005. PMID: 33997168; PMCID: PMC8099687.
  • Song M, Yuan F, Li X, Ma X, Yin X, Rouchka EC, Zhang X, Deng Z, Prough RA, McClain CJ. Analysis of sex differences in dietary copper-fructose interaction-induced alterations of gut microbial activity in relation to hepatic steatosis. Biol Sex Differ. 2021 Jan 6;12(1):3. doi: 10.1186/s13293-020-00346-z. PMID: 33407877; PMCID: PMC7789350.