Education and Training

B.Sc.: University of Bombay
M.Sc.: University of Bombay
Ph.D.: University of Kentucky

Research Interests

• Alcohol and Immune Function
• Epigenetics and Immune Function
• HIV

Featured Publications

• Gobejishvili L, Vatsalya V, Avila DV, Feygin YB, McClain CJ, Mokshagundam S, Barve S. Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes. Biomedicines. 2024 May 31;12(6):1227. doi: 10.3390/biomedicines12061227. PMID: 38927434; PMCID: PMC11200675.
• Cook RL, Richards VL, Gullett JM, Lerner BDG, Zhou Z, Porges EC, Wang Y, Kahler CW, Barnett NP, Li Z, Pallikkuth S, Thomas E, Rodriguez A, Bryant KJ, Ghare S, Barve S, Govind V, Dévieux JG, Cohen RA; 30-Day Challenge Research Team. Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial. JMIR Res Protoc. 2024 Apr 2;13:e53684. doi: 10.2196/53684. PMID: 38564243; PMCID: PMC11028398.
• Walter MN, Montoya-Durango D, Rodriguez W, Wang Y, Zhang J, Chariker JH, Rouchka EC, Maldonado C, Bennett A, McClain CJ, Barve S, Gobejishvili L. Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 in sexual dimorphism and susceptibility to alcohol induced liver injury. Front Immunol. 2024 Feb 1;15:1316228. doi: 10.3389/fimmu.2024.1316228. PMID: 38370409; PMCID: PMC10871047.
• Harris LM, Kerr JC, Skidmore BD, Ghare S, Reyes-Vega A, Remenik-Zarauz V, Samanapally H, Anwar RU, Rijal R, Bryant K, Hall MT, Barve S. A conceptual analysis of SBIRT implementation alongside the continuum of PrEP awareness: domains of fit and feasibility. Front Public Health. 2024 Jan 8;11:1310388. doi: 10.3389/fpubh.2023.1310388. PMID: 38259734; PMCID: PMC10801388.
• Ghare S, Gardener H, Ariko T, Gutierrez J, Wright CB, Goldberg RB, Elkind MSV, Cooper GE, Shields CB, Barve S, Rundek T. Osteopontin Is Associated with Dementia in the Presence of Cerebral Small Vessel Disease. Cerebrovasc Dis. 2024;53(4):495-500. doi: 10.1159/000533953. Epub 2023 Sep 6. PMID: 37673055.
• Elnagdy M, Wang Y, Rodriguez W, Zhang J, Bauer P, Wilkey DW, Merchant M, Pan J, Farooqui Z, Cannon R, Rai S, Maldonado C, Barve S, McClain CJ, Gobejishvili L. Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration. J Pathol. 2023 Nov;261(3):361-371. doi: 10.1002/path.6194. Epub 2023 Sep 21. PMID: 37735782; PMCID: PMC10653049.
• Ghare SS, Charpentier BT, Ghooray DT, Zhang J, Vadhanam MV, Reddy S, Joshi-Barve S, McClain CJ, Barve SS. Tributyrin Mitigates Ethanol-Induced Lysine Acetylation of Histone-H3 and p65-NFκB Downregulating CCL2 Expression and Consequent Liver Inflammation and Injury. Nutrients. 2023 Oct 17;15(20):4397. doi: 10.3390/nu15204397. PMID: 37892472; PMCID: PMC10610222.
• Montoya-Durango D, Walter MN, Rodriguez W, Wang Y, Chariker JH, Rouchka EC, Maldonado C, Barve S, McClain CJ, Gobejishvili L. Dysregulated Cyclic Nucleotide Metabolism in Alcohol-Associated Steatohepatitis: Implications for Novel Targeted Therapies. Biology (Basel). 2023 Oct 10;12(10):1321. doi: 10.3390/biology12101321. PMID: 37887031; PMCID: PMC10604143.
• Knibbe CA, Ahmed RU, Wilkins F, Sharma M, Ethridge J, Morgan M, Gibson D, Cooper KB, Howland DR, Vadhanam MV, Barve SS, Davison S, Sherwood LC, Semler J, Abell T, Boakye M. SmartPill™ Administration to Assess Gastrointestinal Function after Spinal Cord Injury in a Porcine Model-A Preliminary Study. Biomedicines. 2023 Jun 7;11(6):1660. doi: 10.3390/biomedicines11061660. PMID: 37371755; PMCID: PMC10295578.
• Jiang M, Li F, Liu Y, Gu Z, Zhang L, Lee J, He L, Vatsalya V, Zhang HG, Deng Z, Zhang X, Chen SY, Guo GL, Barve S, McClain CJ, Feng W. Probiotic-derived nanoparticles inhibit ALD through intestinal miR194 suppression and subsequent FXR activation. Hepatology. 2023 Apr 1;77(4):1164-1180. doi: 10.1002/hep.32608. Epub 2022 Jul 7. PMID: 35689610; PMCID: PMC9741667.