Natalie C. Dupré, Ph.D.

Education: 

B.A., Major: Neuroscience, Minor: Spanish, Middlebury College, Middlebury, VT; 2010
M.S., Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; 2014
Sc.D., Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; 2017
Postdoctoral Fellowship, Department of Medicine (Cancer Epidemiology), Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, MA (Mentor: Rulla Tamimi, ScD); 2017-2018

Curriculum Vitae 

Current Positions: 

Assistant Professor, Department of Epidemiology and Population Health, University of Louisville School of Public Health and Information Sciences
Member, James Graham Brown Cancer Center, University of Louisville 

Contact Information: 

School of Public Health and Information Sciences, Room 230
University of Louisville
485 E. Gray Street
Louisville, KY 40202, USA
Phone: 502-852-4627
Email:  natalie.dupre@louisville.edu

Research Description: 

DuPré joined the Department of Epidemiology and Population Health in November 2018 after completing postdoctoral research training at the Brigham and Women’s Hospital Channing Division of Network Medicine (Boston, MA) and a Curriculum Fellowship for a blended on-campus and online MPH program at the Harvard T.H. Chan School of Public Health.  She currently teaches epidemiology methods courses for the MPH program at UofL SPHIS.  Her long-term research goals are to investigate the role of environmental factors and their biological mechanisms that influence carcinogenesis and cancer progression in humans by combining expertise across cancer, environmental and molecular epidemiology.  Her primary research projects currently include investigating the role of ambient particulate matter exposure on breast tissue gene expression and the role of natural vegetation exposure on breast cancer survival utilizing rich data sources from the Nurses’ Health Study and Nurses’ Health Study II cohorts and writing grants for future research on environmental exposures, breast tissue gene expression, and intermediate markers of breast cancer risk including mammographic density in epidemiologic cohort studies. 

In addition, DuPre has led an epidemiology podcast, Pandemia, to discuss epidemiologic research and concepts by taking a deep dive in to epidemiologic research on topics that are of interest to the public.  She previously received funding to study whether student-led podcasting is an effective and engaging learning tool to apply epidemiologic thinking and public health communication skills. 

Literature Cited: 

  1.   Peng C, DuPre N, VoPham T, Heng YJ, Baker GM, Rubadue CA, Glass K, Sonawane A, Zeleznik O, Kraft P, Hankinson SE, Eliassen AH, Hart JE, Laden F, Tamimi RM.  Low dose environmental radon exposure with breast tumor gene expression.  BMC Cancer 2020;20:695.  doi: 10.1186/s12885-020-07184-7.  PMID: 32723380.  PMCID: PMC7385902
  2. DuPré NC, Blair LK, Moyer S, Cook EF, Little B, Howard J.  Hepatitis A outbreaks associated with the opioid epidemic in Kentucky counties, 2017-2018.  American Journal of Public Health 2020 Sep 1;110(9);1332.  doi: 10.2105/AJHP.2020.305789.  PMID: 32673108.  
  3. Karimi S, DuPre N, McKinney WP, Little B, Patel N, Moyer S. Projecting the Covid-19 Weekly Deaths and Hospitalizations for Jefferson County, Kentucky.  The University of Louisville Journal of Respiratory Infections 2020 Jul 8;4(1).  doi: 10.18297/jri/vol4/iss1/43.
  4. DuPré NC, Heng YJ, Raby BA, Glass K, Hart JE, Chu JH, Askew C, Eliassen AH, Hankinson SE, Kraft P, Laden F, Tamimi RM.  Involvement of fine particulate matter exposure with gene expression pathways in breast tumor and adjacent-normal breast tissue.  Environmental Research 2020 Jul;186:109535.  doi: 10.1016/j.envres.2020.109535.  Epub 2020 Apr 15.  PMID: 32668536.  PMCID: PMC7368092.
  5. Murray EJ, Farland LV, Caniglia EC, Dorans KS, DuPre NC, Hughes KC, Kim IY, Pernar CH, Tanz LJ, Zack RM.  Is This A Portrait of John Graunt? An Art History Mystery.  American Journal of Epidemiology 2020 Oct 1;189(10):1204-1207.  doi: 10.1093/aje/kwz212.  PMID: 31576411.  PMCID: PMC7670870.
  6. VoPham T, Bertrand KA, Jones RR, Deziel NC, DuPré NC, James P, Liu Y, Vieira VM, Tamimi RM, Hart JE, Ward MH, Laden F.  Dioxin exposure and breast cancer risk in a prospective cohort study.  Environmental Research 2020 Jul;186:109516.  doi: 10.1016/j.envres.2020.109516.  Epub 2020 Apr 13.  PMID: 32305677.  PMCID: PMC7363533.
  7. Peng C, Heng YJ, Lu D, DuPre NC, Kensler KH, Glass K, Zeleznik OA, Kraft P, Feldman D, Hankinson SE, Rexrode K, Eliassen AH, Tamimi RM.  Prediagnostic 25-hydroxyvitamin D concentrations in relation to tumor molecular alterations and risk of breast cancer recurrence.  Cancer Epidemiology Biomarkers & Prevention 2020 Jun;29(6):1253-1263.  doi: 10.1158/1055-9965.EPI-19-1217.  Epub 2020 Apr 1.  PMID: 32238406.  PMCID: PMC7284927.
  8. DuPré NC, Hart JE, Holmes MD, Poole EM, James P, Kraft P, Laden F, Tamimi RM.  Particulate matter and traffic-related exposures in relation to breast cancer survival.  Cancer Epidemiology Biomarkers Prevention 2019 Apr;28(4):751-759.  doi: 10.1158/1055-9965.EPI-18-0803.  Epub 2019 Jan 15.  PMID: 30647065.  PMCID: PMC6449193.
  9. VoPham T, Bertrand KA, DuPré NC, James P, Vieira VM, Tamimi RM, Laden F, Hart JE.  Ultraviolet radiation exposure and breast cancer risk in the Nurses' Health Study II.  Environmental Epidemiology 2019;3(4):e057.  doi: 10.1097/EE9.0000000000000057.  Epub 2019 Jun 17.  PMID: 31321375. PMCID: PMC6639017.
  10. Heng YJ, Wang J, Ahearn TU, Brown SB, Zhang X, Ambrosone CB, de Andrade VP, Brufsky AM, Couch FJ, King TA, Modugno F, Vachon CM, DuPre NC, Garcia-Closas M, Troester MA, Hunter DJ, Eliassen AH, Tamimi RM, Hankinson SE, Beck AH.  Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues.  Breast Cancer Research & Treatment 2019 Feb;173(3):667-677.  doi: 10.1007/s10549-018-5034-1.  Epub 2018 Nov 1.  PMID: 30387004.  PMCID: PMC6391202.
  11. DuPre NC, Flavin R, Sfanos KS, Unger RH, To S, Gazeeva E, Fiorentino M, De Marzo AM, Rider JR, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).  Corpora amylacea in prostatectomy tissue and associations with molecular, histological, and lifestyle factors.  Prostate 2018 Nov;78(15):1172-1180.  doi: 10.1002/pros.23692.  Epub 2018 Jul 15.  PMID: 30009541.
  12. Hart JE, Bertrand KA, DuPre N, James P, Vieira VM, VoPham T, Mittleman MR, Tamimi RM, Laden F.  Exposure to hazardous air pollutants and risk of incident breast cancer in the nurses' health study II.  Environmental Health 2018 Mar 27;17(1):28.  doi: 10.1186/s12940-018-0372-3.  PMID: 29587753.  PMCID: PMC5870204.
  13. VoPham T, DuPré N, Tamimi RM, James P, Bertrand KA, Vieira V, Laden F, Hart JE.  Environmental radon exposure and breast cancer risk in the Nurses’ Health Study II.  Environmental Health 2017 Sep 7.  doi: 10.1186/s12940-017-0305-6.  PMID: 28882148.  PMCID: PMC5590193.
  14. Hart JE, Bertrand KA, DuPré N, James P, Vieira VM, Tamimi RM, Laden F.  Long-term particulate matter exposures during adulthood and risk of breast cancer incidence in the Nurses’ Health Study II prospective cohort.  Cancer Epidemiology Biomarkers & Prevention (CEBP) 2016 Aug;25(8):1274-6.  PMID: 27257091.  PMC4970922.
  15. DuPre NC, Hart JE, Bertrand KA, Kraft P, Laden F, Tamimi RM.  Residential particulate matter and distance to roadways in relation to mammographic density: results from the Nurses' Health Studies.  Breast Cancer Research 2017 Nov 23;19(1):124.  doi: 10.1186/s13058-017-0915-5.  PMID: 29169389.  PMCID: PMC5701365.