M. Tariq Malik, Ph.D. MSPH

Education:

B.Sc. (Hons)., University of Karachi, Pakistan, 1985
M.Sc., Microbiology, University of Karachi, Pakistan, 1986
MSPH, Epidemiology and International Health, University of Alabama at Birmingham, Alabama, 2000
Ph.D., Molecular Biology and Biochemistry, University of Louisville, Kentucky, 2006
CPHE, Certificate in Health Professional Education, University of Louisville, Kentucky 2010
MT, Certificate in Medical Technologist, Aga Khan Medical University, Karachi Pakistan, 1992
Postdoctoral Fellowship, Department of Biochemistry, University of Louisville, Kentucky, 2007-08
Postdoctoral Fellowship, James Graham Brown Cancer Center, University of Louisville, Kentucky 2008-12

Curriculum Vitae

Current Positions:

Assistant Professor, Department of Medicine, University of Louisville School of Medicine
Member, James Graham Brown Cancer Center

Contact Information:

Clinical and Translational Research Buliding Room 308
Univerity of Louisville
505 S Hancock St.
Louisville, KY 40202
Phone: 502-852-1445

Email: tariq.malik@louisville.edu

Research Description:

Literature Cited:

  1. Malik MT, O'Toole MG, Casson LK, Thomas SD, Bardi GT, Reyes-Reyes EM, Ng CK, Kang KA, Bates PJ. AS1411-conjugated gold nanospheres and their potential for breast cancer therapy. Oncotarget. 2015 Jun 3. [Epub ahead of print] PubMed PMID: 26045302.
  2. Junling Li, Huaiyu Zheng, Paula J. Bates. Mohammad T. Malik, Xiao-Feng Li, John O Trent, Paula J. Bates, Ng Chin (2013). Aptamer Imaging with Cu-64 Labeled AS1411: Preliminary Assessment in Lung Cancer". Nucl Med. Bio. 2014 Feb; 41(2):179-85. PIMD: 24373858
  3. Tariq Hamid, Mohammad T Malik, Robert P. Millar, and Kakar S.S. Protein kinase A serves as a primary pathway in activation of Nur77 expression by gonadotropin-releasing hormone in the LßT2 mouse pituitary gonadotroph tumor cell line. International Journal of Oncology 2008, 33: 1055-1064. PMID: 18949369
  4. Larry D. B.  Malik M.T, Nanez A, Powell WD, Ramos KS, Andrew A, and Dean WL. PLASMA MEMBRANE Ca2+-ATPase ASSOCIATES WITH CLP36, alpha-ACTININ and ACTIN IN HUMAN PLATELETS. Thrombosis and Hemostatsis 2007 April, 97(4): 587-97. PMID: 17393022
  5. L. D Bozulic,Malik M.T., and W. L. Dean. Effects of plasma membrane Ca2+ ATPase tyrosine phosphorylation on human platelet function. Thrombosis and Hemostatsis 2007 May, 5(5): 1041-6. PMID: 17461933
  6. El-Naggar SM., Malik M.T., Alvin Martin, Joseph. P. Moore, Mary Proctor, Tariq Hamid and Sham S. Kakar. Development of Cystic Glandular Hyperplasia of the Endometrium in MISIIP-PTTG Transgenic Mice. Journal of Endocrinology. 2007 194: 1-14. PMID: 17592032
  7. El-Naggar SM*., Malik M.T. *, and Sham S. Kakar (* Authors contributed equally) Small interfering RNA against PTTG: A novel therapy for ovarian cancer treatment. Int. J Oncol. 2007 Jul; 31(1): 137-43. PMID: 17549414
  8. Malik M.T, and Sham S Kakar. Regulation of angiogenesis and invasion by human pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinases-2 (MMP-2). Mol. Cancer: 2006 Nov, 10(5): 61. PMID: 17096843
  9. Kakar SS,Malik MT.  Suppression of lung cancer with siRNA targeting PTTG. 2006, International Journal of Oncology, Aug, 29(2): 385-95. PMID: 16820881
  10. Hamid T *, Malik MT *, Kakar SS, (* Authors contributed equally). Ectopic expression of PTTG1 / Securin promotes tumorigenesis in human kidney cells. Mol. Cancer, 2005 Jan, 13;4(1):3. PMID: 15649325
  11. Kakar SS, Malik MT, Winters SJ, Mazhawidza W 2004 Gonadotropin-releasing hormone receptors: structure, expression, and signaling transduction. Vitam Horm 69:151-207. PMID: 15196882
  12. Kakar SS,Malik MT, Winters SJ 2002 Gonadotropin-releasing hormone receptor: cloning, expression and transcriptional regulation. Prog Brain Res 141:129-47. PMID: 12508566
  13. Khan AJ, Luby SP, Malik MT, Fikree F, et al. 2000 Unsafe injections and the transmission of hepatitis B and C in a periurban community in Pakistan. Bull World Health Organ 78:956-63. PMID: 10994278
  14. Sheikh A, Khan A, Malik T, Fisher-Hoch SP 1997 Cholera in a developing megacity; Karachi, Pakistan. Epidemiol Infect 119:287-92. PMID: 9440430

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