The Administrative Core (Core A) is responsible for the day-to-day operation of the MT-COBRE program.  The overall goal of the Phase III application of the Molecular Targets COBRE (MT-COBRE) is to ensure that the novel targets and compounds identified by MT-COBRE faculty are translated to pivotal human clinical trials.  Under Dr. Miller’s direction, the Administrative Core will provide budgetary management, core oversight, management of the Pilot Grant Program and monitor progress of the MT-COBRE faculty.  The MT-COBRE Administrative Assistant and the Program Coordinator report to the MT-COBRE PIs (Dr. Miller and Dr. Eaton) through this core.  The Administrative Core is responsible for organizing all committee meetings including those of the Steering Committee, the Internal Advisory Committee and the External Advisory Committee.  It will provide regular evaluations of research core function and fiscal status.  This Core also will provide the requisite reports to the NIH Program administration on an annual basis.  During the first ten years of MT-COBRE funding, the Administrative Core provided very important support to all of the MT-COBRE faculty and played an important role in the overall success of the program.  This core will assume an even more important role during Phase III of the MT-COBRE.