Research
The Division of Gastroenterology/Hepatology supports a long tradition of cutting-edge basic and clinical research conducted by outstanding faculty, who are integrated into the research enterprise of the University of Louisville. We are dedicated to discovering and teaching new knowledge of gastrointestinal and liver diseases, including Crohn's disease, inflammatory bowel disease, motility disorders, Barrett's esophagus, gastroesophageal reflux, NASH, hepatic encephalopathy, hepatitis, and liver transplantation. Our dedication has resulted in more effective methods of prevention, diagnosis and treatment. We are privileged to have several of our faculty who serve as presidents of nationally-recognized societies and editorial positions of leading gastroenterology journals.
Dr. Ashutosh Barve studies GI cancers, especially liver cancer.
Dr. Shirish Barve examines immunosuppression in ALD and epigenetic changes in ALD. A new area of research for this lab is the role of alcohol in HIV therapy hepatotoxicity.
Dr. Matthew Cave is examining the role of industrial pollutants in the development of liver disease.
Dr. Gerald Dryden is exploring the role of Green Tea Polyphenols in treating inflammatory bowel disease.
Dr. Craig McClain was the first to describe dysregulated cytokine metabolism in alcoholic liver disease two decades ago. He has recently been awarded a Alcohol Research Center grant by the NIH.
Dr. Stephen McClave is site PI for an NIH-funded study on pancreatitis.
Dr. John Wo studies motility problems and Barrett’s esophagus.
Dr. Zhanxiang Zhou focuses on zinc and alcoholic liver disease.
Clinical research includes studies are currently being conducted on Hepatitis C, alcoholic liver disease, non-alcoholic steatohepatitis, motility problems, Barrett’s esophagus, inflammatory bowel disease and irritable bowel syndrome.
