IACUC Policies


Welcome to the newly reorganized Policies and Procedures page!  We hope that the format will facilitate your finding and using these documents. 

I. Animal Care and Use

a.       Required Training  Revised February 15, 2024

b.       Animal Acquisition and Transfer  Revised July 20, 2023

c.       Acclimation Periods for Newly Received and Transferred Animals Revised January 18, 2024

d.       Social Housing of Animals  Revised  October 21, 2021

e.       Humane Endpoints  Revised July 21, 2022

f.        Individual Animal Records  Revised January 21, 2021

g.       Adoption of Research Animals  Revised April 21, 2022

h.       Housing of Mice and Rats  Revised April 20, 2023  [Other helpful documents: CMRU Caging Guide]

i.        Obtaining CMRU Facility Access  New May 16, 2024

 II. Reporting Concerns

 a.       Reporting and Investigating Animal Welfare ConcernsRevised April 18, 2024

 b.       Unexpected Findings and Adverse Events  Revised April 18, 2024

III. Occupational Health and Safety

 a.       Individual Risk Assessment and Medical Surveillance  Revised October 15, 2020

IV. IACUC Proposal

a.       Proposal Review and Approval  Revised October 20, 2022

b.       Modification of an Approved Proposal  Revised October 19, 2023

c.       Proposal Expiration  Revised August 20, 2020

d.       Use of Tissue and Tissue Sharing  Revised October 20, 2022

e.       Oversight of Core Animal Laboratories  Revised April 20, 2023

f.        The Use of Chicken/Avian Embryo  Revised April 21, 2022

g.       Research Studies Utilizing Privately Owned AnimalsRevised October 20, 2022

h.       Research Involving Collaborating Institutions  Revised October 20, 2022

i.        Field Investigations  NEW August 20, 2020

V. Laboratory Housing and Transportation

a.       Laboratory and Satellite Rodent Housing  Revised January 18, 2024

b.       PI Maintained Non-Mammalian Housing  Revised July 21, 2022

c.       Transportation of Research Animals  Revised January 18, 2024

d.       Animal Security in Investigator Laboratories  Revised May 19, 2022

e.      Microbiological Monitoring of PI Maintained Animal Rooms Support Areas and Equipment  Revised June 20, 2024

VI. Procedures

a.       Pain and Distress Class Categorization  Revised July 21, 2022

b.       Rodent Breeding Colonies  Revised May 1, 2023  [Other helpful documents: CMRU Caging Guide]

c.       Tissue Harvesting for Rodent Genotyping  Revised August 20, 2020

d.       Rodent Identification  Revised August 20, 2020

e.       Prolonged Physical Restraint  Revised October 21, 2021

f.        Euthanasia of Research Animals  Revised  November 17, 2022

g.       Rodent Anesthesia  Revised May 19, 2022

h.       Food and Fluid Regulation  Revised July 21, 2022

VII. Surgery

a.       Performing Rodent Survival Surgery  Revised August 20, 2020

b.       Use of Postoperative Analgesia  Revised August 20, 2020

c.       Multiple Survival Surgeries  Revised April 20, 2023

VIII. Use of Pharmaceutical, Biological and Chemical Agents

a.       Use of Pharmaceutical-Grade Medications and Outdated Drug Supplies  Revised March 21, 2024

b.       Use of Adjuvants in Rodents and Rabbits  Revised November 17, 2022

c.       Preparation, Storage, and Use of Tribromoethanol (Avertin)Revised April 20, 2023

d.       Hazardous Agent Review and ApprovalApproved 15 October 2020

e.       Testing of Cell Lines and Other Biological Materials for Rodent Pathogens  Revised April 21, 2022

f.        Use and Labeling of Drug Compounds, Dilutions, and Chronic-Use Fluids  Revised June 15, 2023

IX. Animal Care and Use Program

a.       Semi-Annual Program Review  Revised March 16, 2023



Reporting and Investigating Animal Welfare Concerns

The humane care and use of animals is of paramount importance to the University of Louisville. Individuals who may have specific concerns about animal care and treatment are strongly encouraged to report their observations of suspected deficiencies to the Institutional Animal Care and Use Committee (IACUC), Comparative Medicine Research Unit (CMRU), Institutional Official (Executive Vice President for Research and Innovation), or Institutional Compliance Office. Individuals generating a report of concern shall not be discriminated against or be subject to any reprisal for generating the report. Individuals who desire anonymity may be certain that the IACUC will handle a report of concern in confidence to the extent permitted by law.

Reporting and Investigating Animal Welfare Concerns

Below are signs, in both English and Chinese, on how to submit information regarding a Report of Concern (ROC). 

Please print and post in all locations that animal work is performed.

- Click for English sign

- Click for Chinese sign








Adoption of Research Animals

The University of Louisville (UofL) has elected to offer the adoption of animals designated for research or teaching. The adoptable status of an animal is determined by the Attending Veterinarian and/or clinical veterinarian. Adoption is done in consultation with the Principal Investigator and coordinated by the Comparative Medicine Research Unit. Any such adoption shall comply with applicable regulatory guidance and requirements and the associated UofL guidance and procedures.

Adoption of Research Animals Policy

Appendices I-III Adoption Form, Adoption Questionnaire and Animal Adoption Agreement