ULARC Highlights in 2024 Publications

  • Warner JB, Hardesty JE, Song YL, Floyd AT, Deng Z, Jebet A, He L, Zhang X, McClain CJ, Hammock BD, Warner DR, Kirpich IA Hepatic transcriptome and its regulation following soluble epoxide hydrolase inhibition in alcohol-associated liver disease. Am J Pathol. 2024, Jan; 194(1):71-84. PMID: 37925018
  • Hardesty J, Hawthorne M, Day L., Warner J., Warner D, Gritsenko M, Asghar A, Stolz A, Morgan T, McClai C, Jacobs J, Kirpich I. Steroid responsiveness in alcohol-associated hepatitis is linked to glucocorticoid metabolism, mitochondrial repair, and heat shock proteins. Hepatol Commun. 2024; 8(3):e0393. PMID: 38437061
  • Xu R., Liu H, Yuan F, Kim S, Kirpich IA, McClain CJ, Zhang X Lipid Wizard: analysis software for comprehensive two-dimensional liquid chromatography – mass spectrometry-based lipid profiling. Analytical Chemistry. 2024; 96, 5375-5383. PMID: 38523323
  • Hardesty J, Warner J., Wilkey D., Phinney B., Salemi M., Merchant M., McClain C., Warner D., Kirpich I. Hepatic Proteomic Changes Associated with Liver Injury Caused by Alcohol Consumption in Fpr2-/- Mice. Int. J. Mol.Sci. 2024, Sep 11; 25(18), 9807. PMID: 39337294
  • Gripshover TC, Treves RS, Rouchka EC, Chariker JH, Zheng S, Hudson E, Smith ML, Singal AK, McClain CJ, Hardesty JE. Visium spatial transcriptomics and proteomics identifies novel hepatic cell populations and transcriptomic signatures of alcohol-associated hepatitis. Alcohol Clin Exp Res. 2024 Nov 26. doi: 10.1111/acer.15494 PMID: 39592394
  • Chilton PM, Ghare SS, Charpentier BT, Myers SA, Rao AV, Petrosino JF, Hoffman KL, Greenwell JC, Tyagi N, Behera J, Wang Y, Sloan LJ, Zhang J, Shields CB, Cooper GE, Gobejishvili L, Whittemore SR, McClain CJ, Barve SS. Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice. Gut Microbes. 2024 Jan-Dec;16(1):2389319. PMID: 39182227
  • Xu M, Li M, Benz F, Merchant M, McClain CJ, Song M. Ileum Proteomics Identifies Distinct Pathways Associated with Different Dietary Doses of Copper-Fructose Interactions: Implications for the Gut-Liver Axis and MASLD. Nutrients. 2024 Jun 29;16(13):2083. PMID: 38999831
  • Sundaram K, Teng Y, Mu J, Xu Q, Xu F, Sriwastva MK, Zhang L, Park JW, Zhang X, Yan J, Zhang SQ, Merchant ML, Chen S-y, McClain CJ, Dryden GW, Zhang H-G. Outer Membrane Vesicles Released from Garlic Exosome-like Nanoparticles (GaELNs) Train Gut Bacteria that Reverses Type 2 Diabetes via the Gut-Brain Axis. Small. 2024:e2308680. PMID: 38225709
  • Walter MN, Montoya-Durango D, Rodriguez W, Wang Y, Zhang JW, Chariker JH, Rouchka EC, Maldonado C, Bennett A, McClain CJ, Barve S, Gobejishvili L. Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 (MKP1) in sexual dimorphism and susceptibility to alcohol induced liver injury. Front Immunol. 2024 Feb 1:15:1316228. PMID: 38370409
  • Jophlin L, Liu TY, McClain CJ. Nutritional deficiencies in alcohol use disorder/alcohol associated liver disease. Curr Opin Gastroenterol. 2024 Mar 1;40(2):112-117. PMID: 38193343
  • Hardesty JE, McClain CJ Current Pharmacotherapy and Nutrition Therapy of Alcohol-Associated Liver Disease. Clin Liver Dis. 2024 Nov;28(4):731-745. PMID: 39362718
  • Brown K, Funk K, Figueroa Barrientos A, Bailey A, Shrader S, Feng W, McClain CJ, Song ZH. The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut. Cells. 2024 Sep 26;13(19):1618. PMID: 39404382