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Molecular
mechanisms of craniofacial defects such as facial
clefting and neural tube defects
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Regulation
of gene transcription in eukaryotic cells
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Mechanisms
by which drugs and environmental toxins alter embryonic
development via modulation of the signal transduction
pathways of endogenous growth/differentiation factors
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Function
and interplay of a group of genes/gene products which
collectively have growth regulatory potential in the
embryo, such as oncogenes, tumor supressor genes,
cell cycle regulatory proteins, peptide growth factors
and morphogens.
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The
molecular genetic basis of mental retardation
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Clarification
of the role of neural crest cells in craniofacial
and cardiovascular development.
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Assessment
of cognitive and language abilities in infants.
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Pharmacogenetics
of fetal tobacco smoke exposure.
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Molecular
and genetic control of early development of the central
nervous system.
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Obstructive
sleep apnea and learning disabilities.