Alexander Ovechkin, M.D., Ph.D.
- Associate Professor of Neurological Surgery
- Kentucky Spinal Cord Injury Research Center
- Director of Adult NeuroRecovery Program and Respiratory-Cardiovascular Core
- Frazier Rehab Institute and Neuroscience Center
Research Focus:
Scientific interests of my Lab are in the development and implementation of clinical and neurophysiological methods for use in clinical research to examine pulmonary and cardiovascular functions in disease and injury. The focus of this work is the study of the functional impairment of respiratory and cardiovascular systems after spinal cord injury and the effects of new rehabilitative strategies.
Key Publications:
Legg Ditterline BE, Aslan SC, Randall DC, Harkema SJ, Castillo C, Ovechkin AV. (2018) Effects of Respiratory Training on Heart Rate Variability and Baroreflex Sensitivity in Individuals with Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2018. 99(3):423-432, PubMed PMID: 28802811; PMCID: PMC5807237.
Singh G, Behrman AL, Aslan SC, Trimble S, Ovechkin AV. (2018) Respiratory functional and motor control deficits in children with spinal cord injury. Respir Physiol Neurobiol. 2018;247:174-80, PubMed PMID: 29107737; PMCID: PMC5698146.
Aslan SC, Legg Ditterline BE, Park MC, Angeli CA, Rejc E, Chen Y, Ovechkin AV, Krassioukov A, Harkema SJ. (2018) Epidural Spinal Cord Stimulation of Lumbosacral Networks Modulates Arterial Blood Pressure in Individuals with Spinal Cord Injury-Induced Cardiovascular Deficits. Front. 2018;9:565, PMCID: PMC5968099; PubMed PMID: 29867586.
Harkema SJ, Legg Ditterline BE, Siqi Wang, Aslan SC, Angeli CA, Ovechkin AV, Hirsch GA. (2018) Epidural Spinal Cord Stimulation Training and Sustained Recovery of Cardiovascular Function in Individuals with Chronic Cervical Spinal Cord Injury. JAMA Neurol. 2018; doi: 10.1001/jamaneurol.2018.2617.
Aslan SC, McKay WB, Singh G, Ovechkin AV. (2018) Respiratory muscle activation patterns during maximum airway pressure efforts are different in women and men. Respir Physiol Neurobiol. 259, 143-148; NIHMSID: 988855.
Ditterline BE, Aslan SC, Randall DC, Harkema SJ, Ovechkin AV. (2016) Baroreceptor reflex during forced expiratory maneuvers in individuals with chronic spinal cord injury. Respir Physiol Neurobiol. 2016; 229:65-70, NIHMSID: 784743; PMID: 27137412.
Aslan SC, Randall DC, Krassioukov AV, Phillips A, Ovechkin AV. (2016) Respiratory training improves blood pressure regulation in individuals with chronic spinal cord injury. Arch Phys Med Rehabil., 97 (2016), 964-973, PMID: 26718236.
Ovechkin AV, Sayenko DG, Ovechkina EN, Aslan SC, Pitts T, Folz RJ. (2016) Respiratory motor training and neuromuscular plasticity in patients with chronic obstructive pulmonary disease: A pilot study. Respir Physiol Neurobiol. 2016; 229:59-64, NIHMSID: 784364; PMID: 27137413.
Terson de Paleville D, Sayenko D, Aslan S, Folz R, McKay W, Ovechkin A. (2014) Respiratory motor function in seated and supine positions in individuals with chronic spinal cord injury. Respir. Physiol. Neurobiol., 203 (2014), 9-14, NIHMSID: 622501, PMID: 25169115.
Aslan SC, Chopra MK, McKay WB, Folz RJ, Ovechkin AV. (2013) Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment (RMCA) in Individuals with Chronic Spinal Cord Injury. J Vis Exp. 2013;77(e50178):1-10. Epub July 2013. doi: 10.3791/50178, NIHSID: NIHMS456514. PMID: 23912611.
Nitzken M, Bajaj N, Aslan S, Gimel'farb G, El-Baz A, Ovechkin A. (2013) Local Wavelet-Based Filtering of Electromyographic Signals to Eliminate the Electrocardiographic-Induced Artifacts in Patients with Spinal Cord Injury. J Biomed Sci Eng. 2013;6(7B), PMCID: PMC3845519.
Terson de Paleville D, McKay W, Aslan S, Folz R, Sayenko D, Ovechkin A. (2013) Locomotor step training with body weight support improves respiratory motor function in individuals with chronic spinal cord injury. Respir. Physiol. Neurobiol., 189 (2013) 491–497, PMID: 23999001.
Ovechkin AV, Vitaz TW, Terson de Paleville DGL and McKay WB (2013) Quality of residual neuromuscular control and functional deficits in patients with spinal cord injury. Front. Neurol. 4(174), 1-8, PMID: 3819596.
Terson de Paleville DG, McKay WB, Folz RJ, Ovechkin AV. (2011) Respiratory Motor Control Disrupted by Spinal Cord Injury: Mechanisms, Evaluation, and Restoration. Transl Stroke Res. 2011, Dec 1;2(4):463-73. PMID: 22408690.
Ovechkin A, Vitaz T, Terson de Paleville DGL, Aslan S, McKay W. (2010) Evaluation of respiratory muscle activation in individuals with chronic spinal cord injury. Respir. Physiol. Neurobiol., 173(2): 171–178, 2010. PMID: 20692382