Health Outcomes

Cardiopulmonary

A hypothesis: Potential contributions of metals to the pathogenesis of pulmonary artery hypertension

A novel evaluation of endothelial dysfunction ex vivo: "Teaching an Old Drug a New Trick"

Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications

Association between residential greenness and cardiovascular disease risk

Associations between residential exposure to volatile organic compounds and liver injury markers

Cardiovascular effects of particulate air pollution

Cardiovascular injury induced by tobacco products: assessment of risk factors and biomarkers of harm

Chronic benzene exposure aggravates pressure overload-induced cardiac dysfunction

Defining the human envirome: An omics approach for assessing the environmental risk of cardiovascular disease

Effect of vinyl chloride exposure on cardiometabolic toxicity

Electronic cigarette solvents, pulmonary irritation, and endothelial dysfunction: Role of acetaldehyde and formaldehyde

Emerging technology and platforms for cardiotoxicity testing

Exposure to airborne fine particulate matter is associated with impaired endothelial function and biomarkers of oxidative stress and inflammation

Exposure to vinyl chloride and its influence on western diet-induced cardiac remodeling

Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction

Exposure to volatile organic compounds is associated with hypertension in black adults: the Jackson heart study

How irritating! Electronic cigarettes not “95% safer” than combustible cigarettes: Recent mechanistic insights into endothelial dysfunction

Racial/Ethnic discrimination and cardiometabolic diseases: A systematic review

Metabolic pathways for removing reactive aldehydes are diminished in atrophic muscle during heart failure

Myeloid-specific deletion of epsins 1 and 2 reduces atherosclerosis by preventing LRP-1 downregulation

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer

Subclinical markers of cardiovascular toxicity of benzene inhalation in mice

Tobacco smoke and endothelial dysfunction: Role of aldehydes?

TRPA1 channel contributes to myocardial ischemia-reperfusion injury

Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis (MESA)

Metabolic

Altered splicing factor and alternative splicing events in a mouse model of diet- and polychlorinated biphenyl-induced liver disease

Associations between residential volatile organic compound exposures and liver injury markers: The role of biological sex and race

Benzene exposure induces insulin resistance in mice

Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents

Can zinc supplementation attenuate high fat diet-induced non-alcoholic fatty liver disease?

Changes in m6A in steatotic liver disease

Chronic Aroclor 1260 exposure alters the mouse liver proteome, selenoproteins, and metals in steatotic liver disease

Comprehensive, robust, and sensitive UPLC-MS/MS analysis of free biogenic monoamines and their metabolites in urine

Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT24, NAT25B or NAT27B N-acetyltransferase 2 haplotypes

Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity

Disruption of the mouse liver epitranscriptome by long-term Aroclor 1260 exposure

Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis

Effects of environmental polycyclic aromatic hydrocarbons exposure and pro-inflammatory activity on type 2 diabetes mellitus in US adults

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

Environmental pollution and the developmental origins of childhood liver disease

Epidermal growth factor receptor signaling disruption by endocrine and metabolic disrupting chemicals

Hepatic injury caused by the environmental toxicant vinyl chloride is sex-dependent in mice

Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells

Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk

Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver

Investigating the effects of long-term Aroclor 1260 exposure on fatty liver disease in a diet-induced obesity mouse model

Liver Disease in a Residential Cohort With Elevated Polychlorinated Biphenyl Exposures

Mechanisms of environmental contributions to fatty liver disease

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes

Obesity I: Overview and molecular and biochemical mechanisms

Obesity II: establishing causal links between chemical exposures and obesity

Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease

Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes

Polychlorinated biphenyls and nonalcoholic fatty liver disease

Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation

Sex differences in toxicant-associated fatty liver disease

Sex-specific effects of acute chlordane exposure in the context of steatotic liver disease, energy metabolism, and endocrine disruption

Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells

The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol-associated liver disease

Tributyrin inhibits ethanol-induced epigenetic repression of CPT-1A and attenuates hepatic steatosis and injury

Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients

Vinyl chloride dysregulates metabolic homeostasis and enhances diet-induced liver injury in mice

Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction

Whole life exposure to low dose cadmium alters diet-induced NAFLD

Other Diseases

A case for accelerating standards to achieve the FAIR principles of environmental health research experimental data

560G>A (rs4986782) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment

Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Acetylator genotype-dependent dyslipidemia in rats congenic for N-acetyltransferase 2

Associations of bedroom PM2.5, CO2, temperature, humidity, and noise with sleep: An observational actigraphy study

Biological sex as a moderator of work determinants of health: Implications for work and stress

Concentration dependence of human and mouse aryl hydrocarbon receptor responsiveness to polychlorinated biphenyl exposures: Implications for aroclor mixtures

Coronavirus (COVID-19): A Systematic Review and Meta-analysis to Evaluate the Significance of Demographics and Comorbidities

Depression and anxiety in a manganese-exposed community

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells

Functional expression of human arylamine N-acetyltransferase NAT110 and NAT111 alleles: A minireview

Generative AI as a tool for environmental health research translation

Harm perceptions of secondhand e-cigarette aerosol among youth in the United States

Human N-Acetyltransferase 1 and 2 differ in affinity towards acetyl-coenzyme A cofactor and N-hydroxy-arylamine carcinogens

Interactive Web Tool for Standardizing Proteomics Workflow for Liquid Chromatography-Mass Spectrometry Data

Iodine activation: A general method for catalytic enhancement of thiolate monolayer-protected metal clusters

Mortality risk associated with greenness, air pollution, and physical activity in a representative U.S. cohort

Multigroup prediction in lung cancer patients and comparative controls using signature of volatile organic compounds in breath samples

Potential roles of metals in the pathogenesis of pulmonary and systemic hypertension

Proteomic analysis reveals novel mechanisms by which polychlorinated biphenyls compromise the liver promoting diet-induced steatohepatitis

Residential proximity to greenness mitigates the hemodynamic effects of ambient air pollution

Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline

The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

The importance of urban planning: Views of greenness and open space is reversely associated with self-reported views and depressive symptoms

The role of perceived neighborhood cohesion in the association between depressive symptoms and cigarette smoking

Time spent outdoors and sleep normality: A preliminary investigation

Tunable Aminooxy‐Functionalized Monolayer‐Protected Gold Clusters for Nonpolar and Aqueous Oximation Reactions

Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-) transcriptome

Workplace culture and biomarkers of health risk