COVID-19 Projections in Kentucky

Introduction

A team of UofL SPHIS researchers, led by Dr. Seyed Karimi, is projecting trends in COVID-19 cases in Kentucky using a model of epidemic dynamics called the susceptible-exposed-infectious-recovered (SEIR) model. The model allows for measuring the effect of a public health policy intervention to contain an infection.

Check back frequently for updates. In addition to improving the precision of the current projections with new data, the team is working on measuring changes in the transmission of the disease over time. They are also assessing the impact of different  reopening scenarios on the trends of hospitalization and deaths.


Projecting COVID-19 Hospitalizations for Regions 2, 3, and 4 of the Kentucky Regional Hospital Preparedness Program (HPP) Coalition during the Implementation of the State’s “Targeted Measures”

November 30, 2020

On Nov. 18, Gov. Andy Beshear announced that Kentucky would implement new restrictions for restaurants, schools, indoor social  gatherings, gyms/fitness centers, and schools in Kentucky. The SPHIS COVID-19 Projection Team investigated how these targeted measures could affect hospitalizations due to COVID-19 in three regions of Kentucky:

  • Region 2 includes 11 counties (Daviess is the largest) and has an estimated population 374,030.
  • Region 3 includes 15 counties (Jefferson is the largest) and has an estimated population 1,286,637.
  • Region 3 includes 10 counties (Warren is the largest) and has an estimated population 308,919.

 The study found that mid-range and high compliance with the new restrictions is projected to prevent excess hospitalizations and will allow the regions’ hospitals to operate elective surgeries at normal capacity. Projections also showed that without the new measures, the number of active hospitalizations in Region 2 would exceed the number of inpatient beds by mid-January 2021.

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Projecting COVID-19 Hospitalizations and Deaths for Region 3 of the Kentucky Regional Hospital Preparedness Program (HPP) Coalition

November 20, 2020

Region 3 imageThe research team was asked to estimate how Kentucky's newly implemented targeted measures could affect hospitalizations and deaths in Region 3 of the Kentucky Regional Hospital Preparedness Program (HPP) Coalition. Region 3 includes Jefferson County and 14 Surrounding Counties

The study found that compliance with new restrictions is projected to prevent excess hospitalizations and deaths. In contrast, in the absence of (or no compliance with) new restrictions, the number of active hospitalizations and total deaths is expected to be 789 and 1092 by mid-December 2020. Projections also show that without the new measures, the number of active hospitalizations and total deaths is expected to be 1689 and 1932 by mid-January 2021.

Key Takeaways

  • High compliance with the targeted measures (if it reduces transmission rate by 75%) prevents ~690 excess hospitalizations and ~194 deaths by mid-December 2020 and ~1,582 excess hospitalizations and ~970 deaths by mid-January 2021.
  • Even low compliance with the targeted measures (if it reduces transmission rate by 25%) prevents ~355 excess hospitalizations and ~98 deaths by mid-December 2020 and ~933 excess hospitalizations and ~513 deaths by mid-January 2021.
  • Mid-range compliance with the targeted measures (if it reduces transmission rate by 50%) prevents ~574 excess hospitalizations and ~155 deaths by mid-December 2020 and ~1,363 excess hospitalizations and ~828 deaths by mid-January 2010.

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Results of the Observational Surveys of Mask Use and Protective Measures of Indoor Public Areas in Jefferson County, KY during November 5−11, 2020

November 17, 2020


A new report summarizes an observational study of mask use and protective measures in indoor public areas (PAs) of Jefferson County, Kentucky. Surveyors observed 191 indoor public areas during the first wave of data collection: November 5-11, 2020. Surveyors observed the protective measures and mask-wearing behaviors at randomly selected businesses. Researchers also accounted for business type, size, and location in their study design. The study, funded by the Louisville Metro Department of Public Health & Wellness, will be conducted in multiple waves.

Key Findings

  • The level of protective measures available at Jefferson County indoor public areas is low. Protective measures include providing hand sanitizer, sanitizing shopping carts, having a separate entrance and exit, checking visitors’ mask-wearing at the entrance, and providing masks or wipes to visitors.
  • It is common to see unmasked staff and visitors in public areas, and even more common to see incorrectly masked staff and visitors in public areas.
  • Unmasked staff and visitors in Jefferson County public areas are more commonly 19−44-year-old men.

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Mobility Trends in Jefferson County, KY: February 15 to October 18, 2020

October 25, 2020

 Dr. Seyed Karimi studied Google mobility indicators, which indicate the number of people going to work has been continuously increasing while residential and grocery store visits have been continuously decreasing from early September 2020.

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Projecting COVID-19 Deaths and Hospitalizations for Region 4 of the Kentucky Regional Hospital Preparedness Program (HPP) Coalition from August 18 to October 17, 2020

Sept. 2, 2020

Graph from CEHD report 9-2-2020 showing the rate of mask-wearing in KY Region 4 from the NY Times

Dr. Karimi and his colleagues produced this report as part of the team’s collaboration with the Kentucky's Office of Health Data and Analytics, based in the Cabinet for Health and Family Services, and the Kentucky Regional Hospital Preparedness Program (HPP) Coalition. The HPP Region IV consists of ten counties: Allen, Barren, Butler, Edmonson, Hart, Logan, Metcalfe, Monroe, Simpson, and Warren. Warren County includes the city of Bowling Green, the third largest city in Kentucky. The analysis looked out how different rates of mobility and mask-wearing among Region IV residents would affect hospitalizations and deaths. The mask-wearing rate in the region is significantly lower and mobility rates are noticeably higher than those in Jefferson County, for which this research group predicted COVID-19 hospitalization and deaths previously. Also, COVID-19 hospitalizations in this region have been increasing from the beginning of the pandemic. Researchers found that increasing mask wearing is projected to prevent excess hospitalizations and deaths; however, the estimated benefits of increasing mask wearing will be attenuated if mobility increases at high rates. They conclude that mask wearing cannot/will not be able to mitigate high mobility rates.

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Projecting the COVID-19 Deaths and Hospitalizations for Jefferson County, Kentucky from July 16 to September 15, 2020

July 31, 2020

Figure S1.2_H shows Active Hospitalizations

The focus of this report is showing the importance of mask-wearing in managing the number of hospitalizations and preventing additional deaths. Researchers examined moderate and high increases in the mask-wearing rates following the July 10 mask order, the possibility of the order’s reversal, and increases in mobility with the reopening of schools and universities.

Figure S1.2_H (shown left) illustrates the scenario with the greatest compliance with preventive strategies: mask-wearing compliance (i.e., local mask order in effect) and no significant change in mobility (i.e., schools remain closed). This scenario projects that by mid-September, Jefferson County would have approximately 70 active hospitalizations and 270 total deaths. These projections are lower than the study’s status quo scenario (no change in mask-wearing or mobility rates), which shows the number of active hospitalizations increasing to approximately 260 by mid-September.

If the mask order is reversed after a moderate increase in mask-wearing rate and school opening results in a high increase mobility, the numbers of active hospitalizations and total deaths can increase to approximately 350 and 400, respectively, by mid-September. Projections under this scenario are depicted in Figure S6.1_H in the report.

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Projecting the COVID-19 Weekly Hospitalizations and Deaths for Jefferson County, Kentucky

May 13, 2020

Figure 2 Page 14 (5-12-20) More precise data has informed a second modeling study produced by the UofL School of Public Health and Information Sciences and the Louisville Metro Department of Public Health & Wellness. The updated projections show a current plateau in hospitalizations, along with a slight decrease in death rates and a significant decrease in hospitalizations by the end of August, compared to the first report published a couple of weeks ago.

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Projecting the COVID-19 Weekly Deaths, Infections, and Hospitalizations for Jefferson County, Kentucky

April 23, 2020

Projected numbers of total deaths by week under different social distancing scenarios. The status quo in this figure assumes the social distancing measures became effective on March 31 and decreased transmission by 65% (Figure 2.6 in the report). A new modeling study by the UofL School of Public Health and Information Sciences and the Louisville Metro Department of Public Health & Wellness indicates that stringent social distancing measures the city put in place in March have significantly slowed the spread of COVID-19 in the city.

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Research Team

Seyed Karimi, PhD, Assistant Professor, Department of Health Management & System Sciences; Health Economist, Louisville Metro Department of Public Health & Wellness; 

Natalie DuPre, ScD, Assistant Professor, Department of Epidemiology and Population Health

W. Paul McKinney, MD, Professor and Associate Dean, Department of Health Promotion and Behaviorial Sciences

Bert Little, PhD, Professor, Department of Health Management & System Sciences

Riten Mitra, PhD, Associate Professor, Department of Bioinformatics and Biostatistics 

Naiya Patel, MPH, PhD student, Department of Health Management & Systems Sciences

Hamid Zarei, PhD Student, Department of Health Management & System Sciences

Rameez Ul Hassan, MD, PhD Student, Department of Health Management & System Sciences

YuTing Chen, MPH, MS, Center for Health Equity, Louisville Metro Department of Public Health & Wellness

Sarah Moyer, MD, MPH, Director, Louisville Metro Department of Public Health & Wellness; Assistant Professor, Department of Health Management & System Sciences


Contact Information 
Media inquiries — Julie Heflin, julie.heflin@louisville.edu502-852-7987
Questions about the study methods or results — Dr. Seyed Karimin, Seyed.Karimi@louisville.edu

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