Natalie C. DuPré, ScD, MS

Natalie DuPre imageEpidemiology and Population Health
Assistant Professor 
485 E. Gray St, Room 230
Phone: 502-852-4627
Fax: 502-852-3294 
Office Hours By Appointment



ScD – Harvard T.H. Chan School of Public Health (2017) Epidemiology
MS – Harvard T.H. Chan School of Public Health (2014) Epidemiology
BA – Middlebury College (2010) Neuroscience

Dr. Natalie DuPré joined the Department of Epidemiology and Population Health in November 2018 after completing postdoctoral research training at the Brigham and Women’s Hospital Channing Division of Network Medicine (Boston, MA) and a Curriculum Fellowship for a blended on-campus and online MPH program at the Harvard T.H. Chan School of Public Health. She currently teaches epidemiology methods courses for the MPH program at UofL SPHIS. Her long-term research goals are to investigate the role of environmental factors and their biological mechanisms that influence carcinogenesis and cancer progression in humans by combining expertise across cancer, environmental and molecular epidemiology. Her primary research projects currently include investigating the role of ambient particulate matter exposure on breast tissue gene expression and the role of natural vegetation exposure on breast cancer survival utilizing rich data sources from the Nurses’ Health Study and Nurses’Health Study II cohorts and writing grants for future research on environmental exposures, breast tissue gene expression, and intermediate markers of breast cancer risk including mammographic density in epidemiologic cohort studies. She is a current member of the Society for Epidemiologic Research (SER), International Society for Environmental Epidemiology (ISEE), and the American Society of Preventive Oncology (ASPO).

Other Interests: Dr. DuPre has led an epidemiology podcast, Pandemia, to discuss epidemiologic research and concepts by taking a deep dive in to epidemiologic research on topics that are of interest to the public. She previously received funding to study whether student-led podcasting is an effective and engaging learning tool to apply epidemiologic thinking and public health communication skills.


DuPre NC, Hart JE, Holmes MD, Poole EM, James P, Kraft P, Laden F, Tamimi RM. Particulate Matter and Traffic-related Exposures in Relation to Breast Cancer Survival. Cancer Epidemiology, Biomarkers & Prevention. 2019 Jan 15. DOI: 10.1158/1055-9965.EPI-18-0803. PMID: 30647065.

Heng YJ, Wang J, Ahern TU, Brown SB, Zhang X, Ambrosone CB, Piana de Andrade V, Brufsky AM, Couch FJ, King TA, Modugno F, Vachon CM, DuPré N, Garcia-Closas M, Troester MA, Hunter DJ, Eliassen AH, Tamimi RM, Hankinson SE, Beck AH. Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues. Breast Cancer Research and Treatment. 2018 Nov 1. DOI: 10.1007/s10549-018-5034-1. PMID: 30387004.

DuPré N, Flavin R, Sfanos K, Unger R, To S, Gazeeva E, Fiorentino M, DeMarzo A, Rider J, Mucci LA. Corpora amylacea in prostatectomy tissue and associations with molecular, histological and lifestyle factors. The Prostate. 2018 July 15. DOI: 10.1002/pros.23692. PMID: 30009541.

Hart JE, Bertrand KA, DuPré N, James P, Vieira VM, VoPham T, Mittleman MR, Tamimi RM, Laden F. Exposure to Hazard Air Pollutants and Risk of Incident Breast Cancer in the Nurses’ Health Study II. Environmental Health. 2018 Mar 27;17(1):28. PMCID: PMC5870204.

DuPré NC, Hart JE, Bertrand KA, Kraft P, Laden F, Tamimi RM. Residential particulate matter and distance to roadways in relation to mammographic density: results from the Nurses’ Health Studies. Breast Cancer Res. 2017 Nov 23. DOI: 10.1186/s13058-017-0915-5. PMID: 29169389.

VoPham T, DuPré N, Tamimi RM, James P, Bertrand KA, Vieira V, Laden F, Hart JE. Environmental radon exposure and breast cancer risk in the Nurses’ Health Study II. Environmental Health. 2017 Sep 7. DOI: 10.1186/s12940-017-0305-6. PMID: 28882148.

Hart JE, Bertrand KA, DuPré N, James P, Vieira VM, Tamimi RM, Laden F. Long-Term Particulate Matter Exposures During Adulthood and Risk of Breast Cancer Incidence in the Nurses’ Health Study II Prospective Cohort. CEBP. 2016 Jun 2. DOI: 10.1158/1055-9965.EPI-16-0246. PMID: 27257091.

Graff RE, Pettersson A, Lis RT, DuPré N, Jordahl KM, Nuttall E, Rider JR, Fiorentino M, Sesso HD, Kenfield SA, Loda M, Giovannucci EL, Rosner B, Nguyen RL, Sweeney CJ, Mucci LA; on behalf of the Transdisciplinary Prostate Cancer Partnership ToPCaP. The TMPRSS2:ERG fusion and response to androgen deprivation therapy for prostate cancer. Prostate. 2015 Mar 1. doi: 10.1002/pros.22973. PMCID: PMC4424159.

Kenfield SA, Van Blarigan EL, DuPré N, Stampfer MJ, Giovannucci EL, Chan JM. Selenium supplementation and prostate cancer mortality. J Natl Cancer Inst. 2014 Dec 12. doi: 10.1093/jnci/dju360. PMCID: PMC4296194.

Kenfield SA, DuPré N, Richman EL, Stampfer MJ, Chan JM, Giovannucci EL. Mediterranean Diet and Prostate Cancer Risk and Mortality in the Health Professionals Follow-up Study. Eur Urol. 2013 Aug 13. doi: 10.1016/j.eururo.2013.08.009. PMCID: PMC4157361.

Gershman B, Shui IM, Stampfer MJ, Platz EA, Gann PH, Sesso HL, DuPré N, Giovannucci EL, Mucci LA. Prediagnostic Circulating Sex Hormones Are Not Associated with Mortality for Men with Prostate Cancer. Eur Urol. 2013 Jan 1. doi: 10.1016/j.eururo.2013.01.003. PMCID: PMC3664134.

Shui IM, Mucci LA, Kraft P, Tamimi RM, Lindstrom S, Penney KL, Nimptsch K, Hollis BW, DuPré N, Platz EA, Stampfer MJ, Giovannucci E. Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study. JNCI. 2012 May 2; 104(9):690-699. doi: 10.1093/jnci/djs189. PMCID: PMC3341310.

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