Louisville health care workers experienced an increase in SARS-CoV-2 infection from May to July, according to the Co-Immunity Project, the University of Louisville’s groundbreaking initiative to track COVID-19 in Metro Louisville. In July, the Co-Immunity Project tested health care workers as part of the second round of Phase I of the project, which tracks current and previous exposure to SARS-CoV-2, the virus that causes COVID-19, among health care workers. Despite the increase, their rates remained significantly lower than those of the general public, which project leaders believe may be the result of personal protective equipment (PPE) use and other safety procedures.