Publications & Collaborations

Collaborations: | Environmental Cardiology |

Here are some of our publications and presentations that include applications of mass spectrometry

Nerland, D.E., J. Cai, W.M. Pierce, Jr. and F.W. Benz. Covalent binding of acrylonitrile to specific rat liver glutathione-S-transferases in vivo. In press Chem. Res. Toxicol., 2001

Fitzpatrick, J.L., S.L. Ripp, N.B. Smith, W.M. Pierce, Jr. and R.A. Prough. Metabolism of DHEA by Cytochromes P450 in Rodent and Human Liver Microsomal Fractions. In press Arch. Biochem. Biophys. XXX:XX-XX, 2001 .

Ping, P, J Zhang, WM Pierce, Jr. and R. Bolli. Functional Proteomic Analysis of PKC? Signaling Complexes Assocaited with Cardioprotection. Circ Res. Jan 19;88(1):59-62, 2001 .

Madhavi J. Rane, Patricia Y. Coxon, David W. Powell, Rose Webster, Jon B. Klein, Peipei Ping, William Pierce, and Kenneth R. McLeish p38 kinase-dependent MAPKAPK-2 activation functions as PDK2 for AKT in human neutrophils. J. Biol. Chem., Vol. 276, Issue 5, 3517-3523, 2001 .

Thakkar, R.R., O.-L. Wang, M. Zrouga, W. Stillwell, A. Haq, R. Kissling, W.M. Pierce, Jr., N.B. Smith, F.N. Miller and W.D. Ehringer. Docosahexaenoic acid reverses cyclosporin A-induced changes in membrane structure and function. Biochim Biophys Acta Apr 6;1474(2):183-195, 2000 .

Feltzer, R., R.D. Gray, W.M. Pierce and W.L. Dean. Alkaline Proteinase Inhibitor of Pseudomonas aeruginosa: Interaction of Native and N-terminally Truncated Inhibitor Proteins with Pseudomonas Metalloproteinases. J. Biol. Chem., 275(28), 21002-21009, July 14, 2000.

Li J, T-Y Yen, ML Allende, RK Joshi, J Cai, WM Pierce, Jr., E Jaskiewicz, DS Darling, BA Macher and WW Young, Jr. Disulfide bonds of GM2 synthase homodimers: Antiparallel orientation of the catalytic domains. J Biol Chem 2000 Dec 29;275(52):41476-86 .

William M. Pierce Jr., K. Grant Taylor, Leonard C. Waite, Sujan Singh, Jason R. Neale, Xiaoping Tang, and Ned B. Smith. Bone-targeted Estrogens: Anabolic Bone Effects of an Ether-linked 17-O-Estradiol Derivative. J. Bone Mineral Res., 2000

K. Grant Taylor, Jason R. Neale, Sujan Singh, Xiaoping Tang, Peter C. Kulakosky, Valentyn V. Tyulmenkov, Leonard C. Waite, Carolyn M. Klinge, and William M. Pierce, Jr. BONE SELECTIVE ESTROGENS: Estrogen Receptor Alpha Selectivity is a Predictor of in vivo Efficacy. Presented at the annual meeting of the American Chemical Society - Southeast / Southwest Regions. December 2000.

E. Gozal, J.B. Klein, W.M. Pierce, J.A. Scherzer. J.Cai, L.R. Sachleben and D. Gozal. Proteomic analysius of CA1 and CA3 regions of the hippocampus following 6 hours of intermittent hypoxia. Presented at the annual meeting of the Society for Neurosciences.

Klein, J.B., J.J. Williams, J.A. Scherzer, J. Cai, W.M. Pierce and J.M. Arthur. Development of a protein expression database and comparison of rat renal cortical and medullary protein expression using high-throughput proteomic analysis.. J. Am. Soc. Nephrol. 11:409A, 2000.

Arthur, J.M., J.J. Williams, J.A. Scherzer, J. Cai, W.M. Pierce and J.B. Klein. Proteomic identification of proteins involved in magnesium reabsorption in the kidney. J. Am. Soc. Nephrol. 11:557A, 2000.

Song, W., W.M. Pierce, Jr., Y. Saeki, R.A. Prough and R.N. Redinger. Endogenous 7-Oxocholesterol is an Enzymatic Product: Characterization of 7a -Hydroxycholesterol Dehydrogenase Activity of Hamster Liver Microsomes. Arch. Biochem. Biophys., 328: 272-282, 1996 .

Pierce, W.M., Jr., M. Sharir, K.J. Waite, D. Chen and K.K. Kaysinger. Topically active ocular carbonic anhydrase inhibitors: Novel (biscarbonyl)amidothiadiazoles sulfonamides as ocular hypotensive agents. Proc. Soc. Exp. Biol. Med., 203: 360-365, 1993.

Fish, R.H., K.J. Oberhausen, S. Chen, J.F. Richardson, W.M. Pierce, Jr. and R.M. Buchanan. Biomimetic Oxidation Studies. 7. Alkane functionalization with a MMO structural model [Fe2O(OAc)(tris((1-methylylimidazol-2-yl)methyl)amine) 2]3+, in the presence of t-butylhydroperoxide and oxygen gas. Catalysis Letters 18: 357-265, 1993.

King, K.L., N.A. Delamere, S.C. Csukas and W.M. Pierce, Jr.. Metabolism of arachidonic acid by isolated rabbit ciliary epithelium. Exp. Eye Res. 55: 235-241, 1992.

Song, W., W.M. Pierce Jr., R.A. Prough, and R.N. Redinger. Characteristics of cholesterol 7-a -hydroxylase and 7-a -hydroxycholesterol hydroxylase activities of rodent liver. Biochem.Pharmacol. 41: 1439-1447, 1991.

Rodrigues, A.D, D. Fernandez, M.A. Nozarzewski, W.M. Pierce, Jr. and R.A. Prough. Inhibition of hepatic microsomal cytochrome P450-dependent monooxygenase activity by the antioxidant 3-t-butyl-4-hydroxyanisole. Chem. Res. Toxicology 4: 281-289, 1991.

S.D. Gettings, C.B. Brewer, W.M. Pierce Jr., J.A. Peterson, A.D. Rodrigues and R.A. Prough. Enhanced decomposition of oxyferrous cytochrome P450CIA1 (P-450cam) by the chemopreventive agent, 3-tert -butyl-4-hydroxyanisole. Arch. Biochem. Biophys. 276: 500-509, 1990.

T. Yamamoto, W.M. Pierce, Jr., H.E. Hurst, D. Chen and W.J. Waddell. Ethyl carbamate metabolism: in vivo inhibitors and in vitro enzymatic systems. Drug Metabolism and Disposition 18 : 276-280, 1990.

F.W. Benz, D.E. Nerland, W.M. Pierce, Jr. and C. Babiuk. Acute acrylonitrile toxicity: Studies on the mechanism of the antidotal effect of D- and L-cysteine and their N-acetyl derivatives. Toxicol. Appl. Pharmacol. 102: 142-150, 1990.

D.E. Nerland and W.M. Pierce, Jr. Identification of N-acetyl-S-(2,5-dihydroxyphenyl)-L-cysteine as a urinary metabolite of benzene, phenol, and hydroquinone. Drug Metabolism and Disposition 18: 958-961, 1990.

K.J. Oberhausen, J.F. Richardson, W.M. Pierce, Jr. and R.M. Buchanan. Synthesis, structure and properties of a N3 tridentate bis-imidazolyl ligand with copper(II). Polyhedron 8: 659-668, 1989.

M.S. Mashuta, W.M. Pierce, Jr. and R.M. Buchanan. Binuclear Schiff base macrocycles. Inorg. Chim. Acta 158: 227-237, 1989.

J.S. Hurst, C.A. Paterson, P. Bhattacherjee and W.M. Pierce, Jr. Effects of ebselen on arachadonate metabolism by ocular and non-ocular tissues. Biochem. Pharmacol. 38: 3357-3363, 1989.

L.A. Carr, P.P. Rowell and W.M. Pierce, Jr. Effects of subchronic nicotine administration on central dopaminergic mechanisms in the rat. Neurochemical Research 14: 511-515, 1989.

W.M. Pierce, Jr., A.O. Clark and H.E. Hurst. Determination of ethyl carbamate by gas chromatography with flame ionization or mass spectrometric detection. J. Official Analytical Chemists. 71: 781-784, 1988.

W.M. Pierce, Jr. and D.E. Nerland. Qualitative and quantitative analyses of phenol, phenylglucuronide and phenylsulfate in urine and plasma by gas chromatography/mass spectrometry. J. Anal Toxicology, 12: 344-347, 1988.

M.S. Mashuta, T.N. Doman, W.M. Pierce, Jr. and R.M. Buchanan. Synthesis and characterization of a new binucleating Schiff base macrocycle and its nickel(II) and copper(II) complexes. Inorgan. Chim. Acta 145: 21-28, 1988.

W.J. Waddell, C. Marlowe and W.M. Pierce, Jr. Inhibition of the localization of urethane in mouse tissues by ethanol. Food and Chemical Toxicology 25: 527-531, 1987.

R.D. Gray, W.M. Pierce, Jr., J.W. Harrod, Jr., and J.M. Rademacher. Inhibition of thermolysin by bifunctional N-carboxyalkyl dipeptides. Arch. Biochem. Biophys. 256: 692-698, 1987.

T.I. Senler, W.L. Dean, W.M. Pierce, Jr. and J.L. Witliff. Procedures for measuring Cytochrome P-450-dependent hydroxylation activity in reproductive tissues. Anal. Biochem. 144: 152-158, 1985.

W.M. Pierce, Jr., J.J. Schlager, R.J. Madden and H.E. Hurst. A simple, rapid synthesis of caffeine-1,7-13C. J. Labelled Compounds and Radiopharmaceuticals 21: 187-192, 1984.