Chin Ng, Ph.D.

Associate Professor

Department of Radiology


University of Louisville Hospital, 530 S. Jackson St. 502-852-5875 ckng0001@louisville.edu

Education

  • Ph.D., University of Wisconsin-Madison, WI
  • M.S., University of Wisconsin-Madison, WI
  • B.S., Purdue University, Fort Wayne, IN

Postgraduate Training

  • University of California-Los Angeles, CA
    Nuclear Medicine and Biophysics, 1989-1991

Specialty Interests:

  • Medical Physics, Preclinical Imaging, Molecular Imaging

Research Interests:

  • Validating and characterizing novel imaging probes for multimodality imaging (MRI, PET, SPECT, CT and Optical)
  • Exploring approaches for early detection and monitoring of treatment efficacy of multiple diseases such as infectious diseases, cancer, spinal cord injury, brain diseases, diabetes and heart diseases.
  • Developing thermal laser ablation devices for treating spinal metastases in a MRI environment.

Recent Publications:

  1. Li J, Bates PJ, Trent JO, Ng CK. Labeling G-rich oligonucleotides (GROs) with N-succinimidyl 4-[18-F]fluorobenzoate (S18FB). J Label Compd Radiopharm 2006; 49:1213-1221.
  2. Li J, Trent JO, Bates PJ, Ng CK. Factors affecting the labeling yield of F-18-labeled AS1411. J Label Compd Radiopharm 2007; 50(14):1255-1259.
  3. Li Y, Woodall C, Wo JM, Zheng H, Ng CK, Ray MB, Martin RC. The use of dynamic positron emission tomography imaging for evaluating the carcinogenic progression of intestinal metaplasia to esophageal adenocarcinoma. Cancer Investigation. 2008; 26:278-285.
  4. Hougland, MT, Gao Y, Herman L, Ng CK, Lei Z, El-Mallakh. Positron emission tomography with fluorodeoxyglucose-F18 in an animal model of mania. Psychiatry Research: Neuroimaging. 2008; 164:166-171.
  5. Wang Yi-Xiang J, Ng CK. The impact of quantitative imaging in medicine and surgery: Charting our course for the future. Quant Imaging Med Surg 2011: 1(1): 1-3.
  6. Li J, Gray BD, Pak KY, Ng CK. Radiolabeling and optimizing of zinc(II) dipicolylamine (DPA) with three 18F-prosthetic groups (18F-NFP, 18F-SFB and 18F-FET) as potential imaging agent for metastatic infectious disease. Journal of Labelled Compounds and Radiopharmaceuticals, March 14, 2012. (published online)
  7. Wu A, Zheng H, Krazenzler J, Biller A, Vanover C, Proctor M, Sherwood L, Steffen M, Ng C, Mollular DJ, Jonsson CB. Thoracic Anatomy by 18F-FDG PET/CT Imaging. Journal of Laboratory Animal Research, 2012 (published online: Issue of Neurobiology of Addictive Behaviors).
  8. Jonsson CB, Camp JV, Wu A, Zheng H, Kraenzle JL, Biller AE, Vanover CD, Chu YK, Ng CK, Proctor M, Sherwood L, Steffen MC, Mollura DJ. Molecular imaging reveals a progressive pulmonary inflammation in lower airways in ferrets infected with 2009 H1N1 pandemic influenza virus. PLoS ONE 7(7):1-12, July 2012.
  9. Huang T, Li J, Jiang H, Ng CK, Civelek CA, Postel GC, Shen B, Li XF. Tumor microenvironment dependent F-18 FDG, F-18 FLT and F-18 MISO uptake: A pilot preclinical study in mouse models of human non-small cell lung cancer. J Nucl Med 53(8):1262-1268, 2012.
  10. Huang T, Civelek AC, Zheng H, Ng CK, Duan X, Li J, Postel GC, Shen B, Li X. 18F-misonidazole PET imaging of hypoxia in micrometastases and macroscopic xenografts of human non-small cell lung cancer: a correlation with autoradiography and histological findings. Am J Nucl Med Mol Imaging 3(2):142-153, 2013.
  11. Downs RK, Bashir MH, Ng CK, Heidenreich JO. Quantitative contrast ratio comparison between T1 (TSE at 1.5T, FLAIR at 3T), magnetization prepared rapid gradient echo and subtraction imaging at 1.5T and 3T. Quant Imaging Med Surg 2013 May 13. doi: 10.3978/j.issn.2223-4292.2013.05.02
  12. LeBlanc AJ, Nguygen QT, Touroo JS, Aird AL, Chang RC, Ng CK, Hoying JB, Williams SK. Adipose-derived cell construct stabilizes heart function and increases microvascular perfusion in an established infarct. Stem Cells Translational Medicine, 2013 (2).