Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

  • Associate Professor of Medicine
University of Louisville Health Care Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6189 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Hepatology; Nutrition; Liver Transplantation

 

Board Certifications

  • American Board of Internal Medicine -
    Gastroenterology / Transplant Hepatology

Education and Training

  • Medical School: University of Kentucky
  • Residency: Washington University Barnes-Jewish Hospital
  • Fellowship: University of Louisville

 

Recent Publications

    • Wahlang B, Song M, Beier JI, Cameron Falkner K, Al-Eryani L, Clair HB, Prough RA, Osborne TS, Malarkey DE, Christopher States J, Cave MC. Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):380-90. doi: 10.1016/j.taap.2014.06.019. Epub 2014 Jul 3. PubMed PMID: 24998970; PubMed Central PMCID: PMC4225625.
    • Wahlang B, Falkner KC, Clair HB, Al-Eryani L, Prough RA, States JC, Coslo DM, Omiecinski CJ, Cave MC. Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture. Toxicol Sci. 2014 Aug 1;140(2):283-97. doi: 10.1093/toxsci/kfu083. Epub 2014 May 8. PubMed PMID: 24812009; PubMed Central PMCID: PMC4176050.
    • Ghare SS, Joshi-Barve S, Moghe A, Patil M, Barker DF, Gobejishvili L, Brock GN, Cave M, McClain CJ, Barve SS. Coordinated histone H3 methylation and acetylation regulate physiologic and pathologic fas ligand gene expression in human CD4+ T cells. J Immunol. 2014 Jul 1;193(1):412-21. doi: 10.4049/jimmunol.1400055. Epub 2014 Jun 4. PubMed PMID: 24899502.
    • Shi X, Wahlang B, Wei X, Yin X, Falkner KC, Prough RA, Kim SH, Mueller EG, McClain CJ, Cave M, Zhang X. Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease. J Proteome Res. 2012 Jul 6;11(7):3805-15. doi: 10.1021/pr300297z. Epub 2012 Jun 21. PubMed PMID: 22686559; PubMed Central PMCID: PMC3391350.
    • Mohammad MK, Zhou Z, Cave M, Barve A, McClain CJ. Zinc and liver disease. Nutr Clin Pract. 2012 Feb;27(1):8-20. doi: 10.1177/0884533611433534. Review. Erratum in: Nutr Clin Pract. 2012 Apr;27(2):305. Mohommad, Mohammad K [corrected to Mohammad, Mohammad K]. PubMed PMID: 22307488.
    • Zhong W, McClain CJ, Cave M, Kang YJ, Zhou Z. The role of zinc deficiency in alcohol-induced intestinal barrier dysfunction. Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G625-33. doi: 10.1152/ajpgi.00350.2009. Epub 2010 Feb 18. PubMed PMID: 20167873; PubMed Central PMCID: PMC2867425.
    • Joshi-Barve S, Amancherla K, Patil M, Bhatnagar A, Mathews S, Gobejishvili L, Cave M, McClain C, Barve S. Acrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C. Free Radic Biol Med. 2009 Jul 1;47(1):47-54. doi: 10.1016/j.freeradbiomed.2009.03.021. Epub 2009 Apr 1. PubMed PMID: 19345260; PubMed Central PMCID: PMC3947765.
    • Joshi-Barve S, Barve SS, Amancherla K, Gobejishvili L, Hill D, Cave M, Hote P, McClain CJ. Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes. Hepatology. 2007 Sep;46(3):823-30. PubMed PMID: 17680645.
    • Hurt RT, Frazier TH, Matheson PJ, Cave MC, Garrison RN, McClain CJ, McClave SA. Obesity and inflammation: III. Curr Gastroenterol Rep. 2007 Aug;9(4):307-8. PubMed PMID: 17883979.
    • Hurt RT, Frazier TH, Matheson PJ, Cave MC, Garrison RN, McClain CJ, McClave SA. Obesity and inflammation: II. Curr Gastroenterol Rep. 2007 Aug;9(4):306-7. PubMed PMID: 17883978.