Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

Matthew C. Cave, M.D.

  • Associate Professor of Medicine
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Hepatology; Nutrition; Liver Transplantation

 

Board Certifications

  • American Board of Internal Medicine -
    Gastroenterology / Transplant Hepatology

Education and Training

  • Medical School: University of Kentucky
  • Residency: Washington University Barnes-Jewish Hospital
  • Fellowship: University of Louisville

 

Recent Publications

      • Cave MC, Clair HB, Hardesty JE, Falkner KC, Feng W, Clark BJ, Sidey J, Shi H, Aqel BA, McClain CJ, Prough RA. Nuclear receptors and nonalcoholic fatty liver disease. Biochim Biophys Acta. 2016 Mar 4. pii: S1874-9399(16)30041-4. doi: 10.1016/j.bbagrm.2016.03.002. [Epub ahead of print] PubMed PMID: 26962021.
      • Song M, Chen T, Prough RA, Cave MC, McClain CJ. Chronic Alcohol Consumption Causes Liver Injury in High-Fructose-Fed Male Mice Through Enhanced Hepatic Inflammatory Response. Alcohol Clin Exp Res. 2016 Mar;40(3):518-528. doi: 10.1111/acer.12994. Epub 2016 Feb 9. PubMed PMID: 26858005.
      • Crittenden NE, Buchanan LA, Pinkston CM, Cave B, Barve A, Marsano L, McClain CJ, Jones CM, Marvin MR, Davis EG, Kuns-Adkins CB, Gedaly R, Brock G, Shah MB, Rosenau J, Cave MC. Simeprevir and sofosbuvir with or without ribavirin to treat recurrent genotype 1 hepatitis C virus infection after orthotopic liver transplantation. Liver Transpl. 2016 Feb 25. doi: 10.1002/lt.24422. [Epub ahead of print] PubMed PMID: 26915588.
      • Wahlang B, Prough RA, Falkner KC, Hardesty JE, Song M, Clair HB, Clark BJ, States JC, Arteel GE, Cave MC. Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. Toxicol Sci. 2016 Feb;149(2):396-410. doi: 10.1093/toxsci/kfv250. Epub 2015 Nov 25. PubMed PMID: 26612838; PubMed Central PMCID: PMC4751229.
      • Kirpich IA, Miller ME, Cave MC, Joshi-Barve S, McClain CJ. Alcoholic Liver Disease: Update on the Role of Dietary Fat. Biomolecules. 2016 Jan 6;6(1). pii: E1. doi: 10.3390/biom6010001. Review. PubMed PMID: 26751488; PubMed Central PMCID: PMC4808795.
      • Jiang M, Klein M, Zanger UM, Mohammad MK, Cave MC, Gaikwad NW, Dias NJ, Selcer KW, Guo Y, He J, Zhang X, Shen Q, Qin W, Li J, Li S, Xie W. Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease. J Hepatol. 2016 Jan;64(1):44-52. doi: 10.1016/j.jhep.2015.07.022. Epub 2015 Jul 26. PubMed PMID: 26220752; PubMed Central PMCID: PMC4691383.
      • Wahlang B, Song M, Beier JI, Cameron Falkner K, Al-Eryani L, Clair HB, Prough RA, Osborne TS, Malarkey DE, Christopher States J, Cave MC. Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):380-90. doi: 10.1016/j.taap.2014.06.019. Epub 2014 Jul 3. PubMed PMID: 24998970; PubMed Central PMCID: PMC4225625.
      • Wahlang B, Falkner KC, Clair HB, Al-Eryani L, Prough RA, States JC, Coslo DM, Omiecinski CJ, Cave MC. Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture. Toxicol Sci. 2014 Aug 1;140(2):283-97. doi: 10.1093/toxsci/kfu083. Epub 2014 May 8. PubMed PMID: 24812009; PubMed Central PMCID: PMC4176050.
      • Ghare SS, Joshi-Barve S, Moghe A, Patil M, Barker DF, Gobejishvili L, Brock GN, Cave M, McClain CJ, Barve SS. Coordinated histone H3 methylation and acetylation regulate physiologic and pathologic fas ligand gene expression in human CD4+ T cells. J Immunol. 2014 Jul 1;193(1):412-21. doi: 10.4049/jimmunol.1400055. Epub 2014 Jun 4. PubMed PMID: 24899502.
      • Shi X, Wahlang B, Wei X, Yin X, Falkner KC, Prough RA, Kim SH, Mueller EG, McClain CJ, Cave M, Zhang X. Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease. J Proteome Res.2012 Jul 6;11(7):3805-15. doi: 10.1021/pr300297z. Epub 2012 Jun 21. PubMed PMID: 22686559; PubMed Central PMCID: PMC3391350.