Roberto Bolli, M.D., FAHA

Roberto Bolli, M.D., FAHA

Robert Bolli, M.D.

Roberto Bolli, M.D., FAHA

  • Professor of Medicine, Physiology and Biophysics
  • Jewish Hospital Heart and Lung Institute Distinguished Chair in Cardiology
  • Chief, Division of Cardiovascular Medicine
  • Executive Vice Chair, Department of Medicine
  • Director, Institute of Molecular Cardiology
  • Scientific Director, Cardiovascular Innovation Institute
  • Distinguished University Scholar
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959 - Academic Office

Clinical Expertise
Cardiology; Cardiovascular Disease


Board Certification

  • American Board of Internal Medicine -
    Internal Medicine / Cardiovascular Disease

Education and Training

  • Medical School: University of Perugia, Italy
  • Residency: Baylor College of Medicine
  • Fellowship: National Institutes of Health; Baylor College of Medicine



Recent Publications

        • Tang XL, Li Q, Rokosh G, Sanganalmath SK, Chen N, Ou Q, Stowers H, Hunt G, Bolli R. Long-Term Outcome of Administration of c-kitPOS Cardiac Progenitor Cells After Acute Myocardial Infarction: Transplanted Cells Do not Become Cardiomyocytes, but Structural and Functional Improvement and Proliferation of Endogenous Cells Persist for at Least One Year. Circ Res. 2016 Apr 1;118(7):1091-105. doi: 10.1161/CIRCRESAHA.115.307647. Epub 2016 Feb 2. PubMed PMID: 26838790; PubMed Central PMCID: PMC4818175.
        • Khan AR, Farid TA, Pathan A, Tripathi A, Ghafghazi S, Wysoczynski M, Bolli R. Impact of Cell Therapy on Myocardial Perfusion and Cardiovascular Outcomes in Patients With Angina Refractory to Medical Therapy: A Systematic Review and Meta-Analysis. Circ Res. 2016 Mar 18;118(6):984-93. doi: 10.1161/CIRCRESAHA.115.308056. Epub 2016 Jan 13. PubMed PMID: 26838794; PubMed Central PMCID: PMC4798914.
        • Golpanian S, Schulman IH, Ebert RF, Heldman AW, DiFede DL, Yang PC, Wu JC, Bolli R, Perin EC, Moyé L, Simari RD, Wolf A, Hare JM; Cardiovascular Cell Therapy Research Network. Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease. Stem Cells Transl Med. 2016 Feb;5(2):186-91. doi: 10.5966/sctm.2015-0101. Epub 2015 Dec 18. PubMed PMID: 26683870; PubMed Central PMCID: PMC4729551.
        • Cai C, Guo Y, Teng L, Nong Y, Tan M, Book MJ, Zhu X, Wang XL, Du J, Wu WJ, Xie W, Hong KU, Li Q, Bolli R. Preconditioning Human Cardiac Stem Cells with an HO-1 Inducer Exerts Beneficial Effects After Cell Transplantation in the Infarcted Murine Heart. Stem Cells. 2015 Dec;33(12):3596-607. doi: 10.1002/stem.2198. Epub 2015 Sep 23. PubMed PMID: 26299779; PubMed Central PMCID: PMC4766973.
        • Taylor DA, Perin EC, Willerson JT, Zierold C, Resende M, Carlson M, Nestor B, Wise E, Orozco A, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Traverse JH, Cooke JP, Schutt RC, Bhatnagar A, Grant MB, Lai D, Johnstone BH, Sayre SL, Moyé L, Ebert RF, Bolli R, Simari RD, Cogle CR. Identification of Bone Marrow Cell Subpopulations Associated with Improved Functional Outcomes in Patients with Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial. Cell Transplant. 2015 Nov 19. [Epub ahead of print] PubMed PMID: 26590374.
        • Bolli R, Ghafghazi S. Current status of cell therapy for non-ischaemic cardiomyopathy: a brief overview. Eur Heart J. 2015 Nov 7;36(42):2905-8. doi: 10.1093/eurheartj/ehv454. Epub 2015 Sep 10. PubMed PMID: 26358575.
        • Bolli R, Ghafghazi S. Cell Therapy Needs Rigorous Translational Studies in Large Animal Models. J Am Coll Cardiol. 2015 Nov 3;66(18):2000-4. doi: 10.1016/j.jacc.2015.09.002. PubMed PMID: 26516003.
        • Keith MC, Tokita Y, Tang XL, Ghafghazi S, Moore JB 4th, Hong KU, Elmore JB, Amraotkar AR, Guo H, Ganzel BL, Grubb KJ, Flaherty MP, Vajravelu BN, Wysoczynski M, Bolli R. Effect of the stop-flow technique on cardiac retention of c-kit positive human cardiac stem cells after intracoronary infusion in a porcine model of chronic ischemic cardiomyopathy. Basic Res Cardiol. 2015 Sep;110(5):503. doi: 10.1007/s00395-015-0503-8. Epub 2015 Jul 7. PubMed PMID: 26150250.
        • Amraotkar AR, Hargis CW, Cambon AC, Rai SN, Keith MC, Ghafghazi S, Bolli R, DeFilippis AP. Comparison of coliform contamination in non-municipal waters consumed by the Mennonite versus the non-Mennonite rural populations. Environ Health Prev Med. 2015 Sep;20(5):338-46. doi: 10.1007/s12199-015-0472-4. Epub 2015 Jun 12. PubMed PMID: 26068785; PubMed Central PMCID: PMC4550604.
        • Conklin DJ, Guo Y, Jagatheesan G, Kilfoil PJ, Haberzettl P, Hill BG, Baba SP, Guo L, Wetzelberger K, Obal D, Rokosh DG, Prough RA, Prabhu SD, Velayutham M, Zweier JL, Hoetker JD, Riggs DW, Srivastava S, Bolli R, Bhatnagar A. Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury. Circ Res. 2015 Aug 14;117(5):437-49. doi: 10.1161/CIRCRESAHA.114.305518. Epub 2015 Jul 13. PubMed PMID: 26169370.
        • Keith MC, Bolli R. "String theory" of c-kit(pos) cardiac cells: a new paradigm regarding the nature of these cells that may reconcile apparently discrepant results. Circ Res. 2015 Mar 27;116(7):1216-30. doi: 10.1161/CIRCRESAHA.116.305557. Review. Erratum in: Circ Res. 2015 May 22;116(11):e133. PubMed PMID: 25814683; PubMed Central PMCID: PMC4432841.