Roberto Bolli, M.D., FAHA

Roberto Bolli, M.D., FAHA

Robert Bolli, M.D.

Roberto Bolli, M.D., FAHA

  • Professor of Medicine, Physiology and Biophysics
  • Chief, Division of Cardiovascular Medicine
  • Executive Vice Chair, Department of Medicine
  • Director, Institute of Molecular Cardiology
  • Scientific Director, Cardiovascular Innovation Institute
  • Jewish Hospital Heart and Lung Institute Distinguished Chair in Cardiology
  • Distinguished University Scholar
University of Louisville Health Care Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959 - Academic Office
502-588-4600 - Patient Appointments

Clinical Expertise
Cardiology; Cardiovascular Disease


Board Certification

  • American Board of Internal Medicine -
    Internal Medicine / Cardiovascular Disease

Education and Training

  • Medical School: University of Perugia, Italy
  • Residency: Baylor College of Medicine
  • Fellowship: National Institutes of Health; Baylor College of Medicine



Recent Publications

      • Jones SP, Tang XL, Guo Y, Steenbergen C, Lefer DJ, Kukreja RC, Kong M, Li Q, Bhushan S, Zhu X, Du J, Nong Y, Stowers HL, Kondo K, Hunt GN, Goodchild TT, Orr A, Chang CC, Ockaili R, Salloum FN, Bolli R. The NHLBI-Sponsored Consortium for preclinicAl assESsment of cARdioprotective Therapies (CAESAR): A New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative Infarct-Sparing Interventions in Mice, Rabbits, and Pigs. Circ Res. 2015 Feb 13;116(4):572-86. doi: 10.1161/CIRCRESAHA.116.305462. Epub 2014 Dec 11. PubMed PMID: 25499773; PubMed Central PMCID: PMC4329104.
      • Wysoczynski M, Ratajczak J, Pedziwiatr D, Rokosh G, Bolli R, Ratajczak MZ. Identification of Heme Oxygenase 1 (HO-1) as a Novel Negative Regulator of Mobilization of Hematopoietic Stem/Progenitor Cells. Stem Cell Rev. 2015 Feb;11(1):110-8. doi: 10.1007/s12015-014-9547-7. PubMed PMID: 25086571; PubMed Central PMCID: PMC4333311.
      • Bolli R. Actions speak much louder than words: for midcareer and senior investigators, the track record of productivity should be paramount in selecting grant recipients. Circ Res. 2014 Dec 5;115(12):962-6. doi: 10.1161/CIRCRESAHA.114.305556. Epub 2014 Nov 4. PubMed PMID: 25371545.
      • Bolli R, Birks E, Flaherty MP, Keith M, Ghafghazi S. Response to letter regarding article, "Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions". Circ Res. 2014 Nov 7;115(11):e33-4. doi: 10.1161/CIRCRESAHA.114.305263. PubMed PMID: 25378533.
      • Brooks AC, Guo Y, Singh M, McCracken J, Xuan YT, Srivastava S, Bolli R, Bhatnagar A. Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning. J Mol Cell Cardiol. 2014 Nov;76:138-47. doi: 10.1016/j.yjmcc.2014.08.011. Epub 2014 Aug 23. PubMed PMID: 25151953; PubMed Central PMCID: PMC4336548.
      • Cogle CR, Wise E, Meacham AM, Zierold C, Traverse JH, Henry TD, Perin EC, Willerson JT, Ellis SG, Carlson M, Zhao DX, Bolli R, Cooke JP, Anwaruddin S, Bhatnagar A, da Graca Cabreira-Hansen M, Grant MB, Lai D, Moyé L, Ebert RF, Olson RE, Sayre SL, Schulman IH, Bosse RC, Scott EW, Simari RD, Pepine CJ, Taylor DA; Cardiovascular Cell Therapy Research Network (CCTRN). Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. Circ Res. 2014 Oct 24;115(10):867-74. doi: 10.1161/CIRCRESAHA.115.304353. Epub 2014 Aug 18. PubMed PMID: 25136078; PubMed Central PMCID: PMC4358751.
      • Madonna R, Geng YJ, Bolli R, Rokosh G, Ferdinandy P, Patterson C, De Caterina  R. Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts. J Biol Chem. 2014 Jul 11;289(28):19585-98. doi: 10.1074/jbc.M113.540559. Epub 2014 May 22. PubMed PMID: 24855642; PubMed Central PMCID: PMC4094070.
      • Hong KU, Bolli R. Cardiac stem cell therapy for cardiac repair. Curr Treat Options Cardiovasc Med. 2014 Jul;16(7):324. doi: 10.1007/s11936-014-0324-3. PubMed PMID: 24903489; PubMed Central PMCID: PMC4055849.
      • Simari RD, Pepine CJ, Traverse JH, Henry TD, Bolli R, Spoon DB, Yeh E, Hare JM, Schulman IH, Anderson RD, Lambert C, Sayre SL, Taylor DA, Ebert RF, Moyé LA. Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network. Circ Res. 2014 May 9;114(10):1564-8. doi: 10.1161/CIRCRESAHA.114.303720. Review. PubMed PMID: 24812350; PubMed Central PMCID: PMC4271539.
      • Bolli R. Reaching out to young investigators. Circ Res. 2014 Mar 14;114(6):930. doi: 10.1161/CIRCRESAHA.114.303709. PubMed PMID: 24625720.