Roberto Bolli, M.D., FAHA, FACC

Roberto Bolli, M.D., FAHA, FACC

Robert Bolli, M.D.

Roberto Bolli, M.D., FAHA, FACC

  • Professor of Medicine, Physiology and Biophysics
  • Jewish Hospital Heart and Lung Institute Distinguished Chair in Cardiology
  • Chief, Division of Cardiovascular Medicine
  • Executive Vice Chair, Department of Medicine
  • Director, Institute of Molecular Cardiology
  • Scientific Director, Cardiovascular Innovation Institute
  • Distinguished University Scholar
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959 - Academic Office

Clinical Expertise
Cardiology; Cardiovascular Disease


Board Certification

  • American Board of Internal Medicine -
    Internal Medicine / Cardiovascular Disease

Education and Training

  • Medical School: University of Perugia, Italy
  • Residency: Baylor College of Medicine
  • Fellowship: National Institutes of Health; Baylor College of Medicine



Featured Publications

Lindsey ML, Bolli R, Canty JM Jr., Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, Recchia FA, Schwartz Longacre L, Ripplinger CM, Van Eyk JE, Heusch G. Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H812-H838. doi: 10.1152/ajpheart.00335.2017. Epub 2018 Jan 12. PubMed PMID: 29351451.

Tang XL, Nakamura S, Li Q, Wysoczynski M, Gumpert AM, Wu WJ, Hunt G, Stowers H, Ou Q, Bolli R. Repeated Administrations of Cardiac Progenitor Cells Are Superior to a Single Administration of an Equivalent Cumulative Dose. J Am Heart Assoc. 2018 Feb 13;7(4). pii: e007400. doi: 10.1161/JAHA.117.007400. PubMed PMID: 29440036; PubMed Central PMCID: PMC5850187.


  • Chamuleau SAJ, van der Naald M, Climent AM, Kraaijeveld AO, Wever KE, Duncker DJ, Fernández-Avilés F, Bolli R; Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Group. Translational Research in Cardiovascular Repair: A Call for a Paradigm Shift. Circ Res. 2018 Jan 19;122(2):310-318. doi: 10.1161/CIRCRESAHA.117.311565. Review. PubMed PMID: 29348252.
  • Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Pinto FJ, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC; TACTICS Writing Group. Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine. Circ Res. 2018 Jan 19;122(2):199-201. doi: 10.1161/CIRCRESAHA.117.312099. PubMed PMID: 29348246.
  • Kahlon A, Vaidya G, Bolli R. Cell therapy for heart disease: current status and future directions. Minerva Cardioangiol. 2018 Jan 10. doi: 10.23736/S0026-4725.18.04596-6. [Epub ahead of print] PubMed PMID: 29327894.
  • Uchida S, Bolli R. Short and Long Noncoding RNAs Regulate the Epigenetic Status of Cells. Antioxid Redox Signal. 2017 Sep 28. doi: 10.1089/ars.2017.7262. [Epub ahead of print] PubMed PMID: 28847161.
  • Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser S, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, Ruiz-Lozano P, Sadek HA, Sussman MA, Hill JA. Cardiomyocyte Regeneration: A Consensus Statement. Circulation. 2017 Aug 15;136(7):680-686. doi: 10.1161/CIRCULATIONAHA.117.029343. Epub 2017 Jul 6. Review. PubMed PMID: 28684531; PubMed Central PMCID: PMC5557671.
  • Yanamandala M, Zhu W, Garry DJ, Kamp TJ, Hare JM, Jun HW, Yoon YS, Bursac N, Prabhu SD, Dorn GW 2nd, Bolli R, Kitsis RN, Zhang J. Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering. J Am Coll Cardiol. 2017 Aug 8;70(6):766-775. doi: 10.1016/j.jacc.2017.06.012. Review. PubMed PMID: 28774384; PubMed Central PMCID: PMC5553556.
  • Moore JB 4th, Zhao J, Fischer AG, Keith MCL, Hagan D, Wysoczynski M, Bolli R. Histone Deacetylase 1 Depletion Activates Human Cardiac Mesenchymal Stromal Cell Proangiogenic Paracrine Signaling Through a Mechanism Requiring Enhanced Basic Fibroblast Growth Factor Synthesis and Secretion. J Am Heart Assoc. 2017 Jul 5;6(7). pii: e006183. doi: 10.1161/JAHA.117.006183. PubMed PMID: 28679560; PubMed Central PMCID: PMC5586316.
  • Jokerst JV, Cauwenberghs N, Kuznetsova T, Haddad F, Sweeney T, Hou J, Rosenberg-Hasson Y, Zhao E, Schutt R, Bolli R, Traverse JH, Pepine CJ, Henry TD, Schulman IH, Moyé L, Taylor DA, Yang PC. Circulating Biomarkers to Identify Responders in Cardiac Cell therapy. Sci Rep. 2017 Jun 30;7(1):4419. doi: 10.1038/s41598-017-04801-7. Erratum in: Sci Rep. 2018 Mar 6;8(1):4257. PubMed PMID: 28667255; PubMed Central PMCID: PMC5493650.