Roberto Bolli, M.D., FAHA, FACC

Robert Bolli, M.D.

Roberto Bolli, M.D., FAHA, FACC

  • Professor of Medicine, Physiology and Biophysics
  • Jewish Hospital Heart and Lung Institute Distinguished Chair in Cardiology
  • Chief, Division of Cardiovascular Medicine
  • Executive Vice Chair, Department of Medicine
  • Director, Institute of Molecular Cardiology
  • Distinguished University Scholar
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959- Academic Office
502-588-4600
- Patient Appointments


Clinical Expertise
Cardiology; Cardiovascular Disease


Board Certification

  • American Board of Internal Medicine -
    Internal Medicine / Cardiovascular Disease

Education and Training

  • Medical School: University of Perugia
  • Residency: Baylor College of Medicine Affiliated Hospitals
  • Fellowship: National Institutes of Health; Baylor College of Medicine

Featured Publications

  • Bolli R, Kahlon A. Time to end the war on cell therapy. Eur J Heart Fail. 2020 Feb 26. doi: 10.1002/ejhf.1767. [Epub ahead of print] PubMed PMID: 32100951.
  • Yang D, O'Brien CG, Ikeda G, Traverse JH, Taylor DA, Henry TD, Bolli R, Yang PC. Meta-analysis of short- and long-term efficacy of mononuclear cell transplantation in patients with myocardial infarction. Am Heart J. 2020 Feb;220:155-175. doi: 10.1016/j.ahj.2019.09.005. Epub 2019 Nov 11. PubMed PMID: 31821904.
  • Wysoczynski M, Bolli R. A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair. Eur Heart J. 2019 Nov 28. pii: ehz787. doi: 10.1093/eurheartj/ehz787. [Epub ahead of print] PubMed PMID: 31778154.
  • Ou Q, Jacobson Z, Abouleisa RRE, Tang XL, Hindi SM, Kumar A, Ivey KN, Giridharan G, El-Baz A, Brittian K, Rood B, Lin YH, Watson SA, Perbellini F, McKinsey TA, Hill BG, Jones SP, Terracciano CM, Bolli R, Mohamed TMA. Physiological Biomimetic Culture System for Pig and Human Heart Slices. Circ Res. 2019 Aug 30;125(6):628-642. doi: 10.1161/CIRCRESAHA.119.314996. Epub 2019 Jul 16. PubMed PMID: 31310161; PubMed Central PMCID: PMC6715512.
  • Wysoczynski M, Pathan A, Moore JB 4th, Farid T, Kim J, Nasr M, Kang Y, Li H, Bolli R. Pro-Angiogenic Actions of CMC-Derived Extracellular Vesicles Rely on Selective Packaging of Angiopoietin 1 and 2, but Not FGF-2 and VEGF. Stem Cell Rev Rep. 2019 Aug;15(4):530-542. doi: 10.1007/s12015-019-09891-6. PubMed PMID: 31102187; PubMed Central PMCID: PMC6941436.
  • Guo Y, Nong Y, Tukaye DN, Rokosh G, Du J, Zhu X, Book M, Tomlin A, Li Q, Bolli R. Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury. Basic Res Cardiol. 2019 Jul 5;114(5):32. doi: 10.1007/s00395-019-0741-2. PubMed PMID: 31278427.
  • Bolli R, Wysoczynski M. Human Embryonic Stem Cell-Derived Cardiomyocytes. Circ Res. 2019 Apr 12;124(8):1157-1159. doi: 10.1161/CIRCRESAHA.119.314869. PubMed PMID: 30973816.
  • Conklin DJ, Guo Y, Nystoriak MA, Jagatheesan G, Obal D, Kilfoil PJ, Hoetker JD, Guo L, Bolli R, Bhatnagar A. TRPA1 channel contributes to myocardial ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H889-H899. doi: 10.1152/ajpheart.00106.2018. Epub 2019 Feb 8. PubMed PMID: 30735434; PubMed Central PMCID: PMC6483018.
  • Grigorian Shamagian L, Madonna R, Taylor D, Climent AM, Prosper F, Bras-Rosario L, Bayes-Genis A, Ferdinandy P, Fernández-Avilés F, Izpisua Belmonte JC, Fuster V, Bolli R. Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine. Circ Res. 2019 Mar 15;124(6):938-951. doi: 10.1161/CIRCRESAHA.118.313795. Review. PubMed PMID: 30870121; PubMed Central PMCID: PMC6442739.
  • Vrtovec B, Bolli R. Potential Strategies for Clinical Translation of Repeated Cell Therapy. Circ Res. 2019 Mar;124(5):690-692. doi: 10.1161/CIRCRESAHA.118.314653. PubMed PMID: 30817255; PubMed Central PMCID: PMC6400294.