Education and Training

• B.Sc.: Wilson College, University of Mumbai
• M.Sc.: LTMM College, University of Mumbai
• Ph.D.: University of Louisville

Research Interests

• Epigenetics
• HIV and Liver Disease

Featured Publications

• Cook RL, Richards VL, Gullett JM, Lerner BDG, Zhou Z, Porges EC, Wang Y, Kahler CW, Barnett NP, Li Z, Pallikkuth S, Thomas E, Rodriguez A, Bryant KJ, Ghare S, Barve S, Govind V, Dévieux JG, Cohen RA; 30-Day Challenge Research Team. Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial. JMIR Res Protoc. 2024 Apr 2;13:e53684. doi: 10.2196/53684. PMID: 38564243; PMCID: PMC11028398.
• Harris LM, Kerr JC, Skidmore BD, Ghare S, Reyes-Vega A, Remenik-Zarauz V, Samanapally H, Anwar RU, Rijal R, Bryant K, Hall MT, Barve S. A conceptual analysis of SBIRT implementation alongside the continuum of PrEP awareness: domains of fit and feasibility. Front Public Health. 2024 Jan 8;11:1310388. doi: 10.3389/fpubh.2023.1310388. PMID: 38259734; PMCID: PMC10801388.
• Ghare S, Gardener H, Ariko T, Gutierrez J, Wright CB, Goldberg RB, Elkind MSV, Cooper GE, Shields CB, Barve S, Rundek T. Osteopontin Is Associated with Dementia in the Presence of Cerebral Small Vessel Disease. Cerebrovasc Dis. 2024;53(4):495-500. doi: 10.1159/000533953. Epub 2023 Sep 6. PMID: 37673055.
• Ghare SS, Charpentier BT, Ghooray DT, Zhang J, Vadhanam MV, Reddy S, Joshi-Barve S, McClain CJ, Barve SS. Tributyrin Mitigates Ethanol-Induced Lysine Acetylation of Histone-H3 and p65-NFκB Downregulating CCL2 Expression and Consequent Liver Inflammation and Injury. Nutrients. 2023 Oct 17;15(20):4397. doi: 10.3390/nu15204397. PMID: 37892472; PMCID: PMC10610222.
• Ghare S, Singhal R, Bryant V, Gautam S, Tirumala CC, Srisailam PK, Reyes-Vega A, Ghooray D, McClain CJ, Hoffman K, Petrosino J, Bryant K, Govind V, Cohen R, Cook RL, Barve S. Age-Associated Gut Dysbiosis, Marked by Loss of Butyrogenic Potential, Correlates With Altered Plasma Tryptophan Metabolites in Older People Living With HIV. J Acquir Immune Defic Syndr. 2022 Feb 1;89(Suppl 1):S56-S64. doi: 10.1097/QAI.0000000000002866. PMID: 35015746; PMCID: PMC8751293.
• Hamorsky KT, Bushau-Sprinkle AM, Kitterman K, Corman JM, DeMarco J, Keith RJ, Bhatnagar A, Fuqua JL, Lasnik A, Joh J, Chung D, Klein J, Flynn J, Gardner M, Barve S, Ghare SS, Palmer KE. Serological assessment of SARS-CoV-2 infection during the first wave of the pandemic in Louisville Kentucky. Sci Rep. 2021 Sep 14;11(1):18285. doi: 10.1038/s41598-021-97423-z. PMID: 34521900; PMCID: PMC8440627.
• Morrissey SM, Geller AE, Hu X, Tieri D, Ding C, Klaes CK, Cooke EA, Woeste MR, Martin ZC, Chen O, Bush SE, Zhang HG, Cavallazzi R, Clifford SP, Chen J, Ghare S, Barve SS, Cai L, Kong M, Rouchka EC, McLeish KR, Uriarte SM, Watson CT, Huang J, Yan J. A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients. JCI Insight. 2021 May 10;6(9):e148435. doi: 10.1172/jci.insight.148435. PMID: 33986193; PMCID: PMC8262329.
• Singhal R, Donde H, Ghare S, Stocke K, Zhang J, Vadhanam M, Reddy S, Gobejishvili L, Chilton P, Joshi-Barve S, Feng W, McClain C, Hoffman K, Petrosino J, Vital M, Barve S. Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice. Gut Microbes. 2021 Jan-Dec;13(1):1946367. doi: 10.1080/19490976.2021.1946367. PMID: 34369304; PMCID: PMC8354657.
• Ghare SS, Chilton PM, Rao AV, Joshi-Barve S, Peyrani P, Reyes Vega A, McClain CJ, Bryant K, Cook RL, Freiberg M, Barve S. Epigenetic Mechanisms Underlying HIV-Infection Induced Susceptibility of CD4+ T Cells to Enhanced Activation-Induced FasL Expression and Cell Death. J Acquir Immune Defic Syndr. 2021 Jan 1;86(1):128-137. doi: 10.1097/QAI.0000000000002526. PMID: 33093334; PMCID: PMC8384352.
• Hong KU, Doll MA, Lykoudi A, Salazar-González RA, Habil MR, Walls KM, Bakr AF, Ghare SS, Barve SS, Arteel GE, Hein DW. Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2. Toxicol Rep. 2020 Sep 28;7:1319-1330. doi: 10.1016/j.toxrep.2020.09.011. PMID: 33083237; PMCID: PMC7553889.