David J. Samuelson, Ph.D.

Assistant Professor

Department of Biochemistry and Molecular Biology


319 Abraham Flexner Way, HSC-A, Room 7083 502-852-7797 502-852-6222 (fax) david.samuelson@louisville.edu

Education

PhD 2001 University of Arizona, Tucson

Post-Doc, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison

Research Group Members

Aaron DenDekker, Graduate Student

Jennifer Sanders, Graduate Student

Bharat Devapatla, Post-Doc

Xin Xu, Post Doc

Aaron Puckett, Technician

Research Interests

Genetic and environmental breast cancer susceptibility.

Selected Publications

Smits BM, Sharma D, Samuelson DJ, Woditschka S, Mau B, Haag JD, Gould MN. (2011) The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast Cancer Res. 2011 Aug 16;13(4):R81.

Sanders J, Haag JD, Samuelson DJ. (2011) Physical confirmation and mapping of overlapping rat mammary carcinoma susceptibility QTLs, Mcs2 and Mcs6. PLoS One. 2011;6(5):e19891. Epub 2011 May 18.

Veillet AL, Haag JD, Remfert JL, Meilahn AL, Samuelson DJ, Gould MN. (2011) Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression. Cancer Prev Res. 2011 Jan;4(1):97-106.

Samuelson DJ, Hesselson SE, Aperavich BA, Zan Y, Haag JD, Trentham-Dietz A, Hampton JM, Mau B, Chen K, Baynes C, Khaw KT, Luben RN, Perkins B, Shah M, Pharoah PD, Dunning AM, Easton DF, Ponder BA, and Gould MN. Rat Mcs5a is a compound QTL with orthologous human loci that associate with breast cancer risk. Proc Natl Acad Sci U S A. 2007; 104: 6299-304.

Samuelson DJ, Aperavich BA, Haag JD, Gould MN. Fine Mapping Reveals Multiple Loci and a Possible Epistatic Interaction within the Mammary Carcinoma Susceptibility Quantitative Trait Locus, Mcs5. Cancer Res. 2005; 65: 9637-42.

Haag JD, Shepel LA, Kolman BD, Monson DM, Benton ME, Watts KT, Waller JL, Lopez-Guajardo CC, Samuelson DJ, Gould MN. Congenic rats reveal three independent Copenhagen alleles within the Mcs1 quantitative trait locus that confer resistance to mammary cancer. Cancer Res. 2003; 63: 5808-12.

Samuelson DJ, Haag JD, Lan H, Monson DM, Shultz MA, Kolman BD, Gould MN. Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats. Carcinogenesis 2003; 24: 1455-60.