July-October 2020 Member Publications

  1. Mazzocco JC, Jagadapillai R, Gozal E, Kong M, Xu Q, Barnes GN, Freedman JH. Disruption of essential metal homeostasis in the brain by cadmium and high-fat diet. Toxicol Rep. 2020 Aug 23;7:1164-1169. doi: 10.1016/j.toxrep.2020.08.005. PMID: 32983904; PMCID: PMC7494587.
  2. Miller I, Scheffer IE, Gunning B, Sanchez-Carpintero R, Gil-Nagel A, Perry MS, Saneto RP, Checketts D, Dunayevich E, Knappertz V for GWPCARE2 Study Group (including G.N. Barnes). Dose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome: A Randomized Clinical Trial. JAMA Neurol. 2020 May 1;77(5):613-621. doi: 10.1001/jamaneurol.2020.0073.
  3. F. El-Gamal, M. Elmogy, A. Mohammed Ghazal, J. Yousaf, X. Qiu, H. Soliman, A. Atwan, H. Frieboes, G. Barnes, and A. El-Baz. (2020) Personalized Computer-Aided Diagnosis for Mild Cognitive Impairment in Alzheimer’s Disease Based on sMRI and11C PiB-PET Analysis, IEEE Access, Volume 8, DOI: 10.1109/ACCESS.2020.3038723.
  4. Y. Elnakieb, M. Ali, A. Soliman, A. Mahmoud, A. Shalaby, N. Alghamdi, M. Ghazal, A. Khalil, A. Switala, R. Keynton, G. Barnes, and A. El-Baz. (2020) Computer Aided Autism Diagnosis Using Diffusion Tensor Imaging. IEEE ACCESS, Volume 8, Digital Object Identifier 10.1109/ACCESS.2020.3032066
  5. Tian Z, Chu T, Shields LBE, Zhu Q, Zhang YP, Kong M, Barnes GN, Wang Y, Shields CB, Cai J. Platelet-Activating Factor Deteriorates Lysophosphatidylcholine-Induced Demyelination Via Its Receptor-Dependent and -Independent Effects. Mol Neurobiol. 2020 Oct;57(10):4069-4081. doi: 10.1007/s12035-020-02003-3. Epub 2020 Jul 13. PMID: 32661728.
  6. Zhang Y, Cao H, Qiu X, Xu D, Chen Y, Barnes GN, Tu Y, Gyabaah AT, Gharbal AHAA, Peng C, Cai J, Cai X. Neuroprotective Effects of Adenosine A1 Receptor Signaling on Cognitive Impairment Induced by Chronic Intermittent Hypoxia in Mice. Front Cell Neurosci. 2020 Jul 9;14:202. doi: 10.3389/fncel.2020.00202. PMID: 32733207; PMCID: PMC7363980.
  7. Baba S, Smith T, Hellmann J, Bhatnagar A, Carter K, Vanhoover A, Caruso J. Space Flight Diet-Induced Deficiency and Response to Gravity-Free Resistive Exercise. Nutrients. 2020 Aug 11;12(8):2400. doi: 10.3390/nu12082400. PMID: 32796546; PMCID: PMC7468946.
  8. Galbraith NJ, Gardner SA, Walker SP, Trainor P, Carter JV, Bishop C, Sarojini H, O'Brien SJ, Bhatnagar A, Polk HC Jr, Galandiuk S. The role and function of IκKα/β in monocyte impairment. Sci Rep. 2020 Jul 22;10(1):12222. doi: 10.1038/s41598-020-68018-x. PMID: 32699255; PMCID: PMC7376008.
  9. Irfan AB, Arab C, DeFilippis AP, Lorkiewicz P, Keith RJ, Xie Z, Bhatnagar A, Carll AP. Smoking Accelerates Atrioventricular Conduction in Humans Concordant with Increased Dopamine Release. Cardiovasc Toxicol. 2020 Oct 12. doi: 10.1007/s12012-020-09610-5. Epub ahead of print. PMID: 33043409.
  10. Rai SN, Qian C, Pan J, Seth A, Srivastava DK, Bhatnagar A. Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients. BMC Med Res Methodol. 2020 Aug 31;20(1):220. doi: 10.1186/s12874-020-01101-z. PMID: 32867708; PMCID: PMC745675
  11. Cave MC. Environmental Pollution and the Developmental Origins of Childhood Liver Disease. Hepatology. 2020 Nov;72(5):1518-1521. doi: 10.1002/hep.31549. PMID: 32910501.
  12. Lin Q, Huang Z, Cai G, Fan X, Yan X, Liu Z, Zhao Z, Li J, Li J, Shi H, Kong M, Zheng MH, Conklin DJ, Epstein PN, Kupper AW, Mohammadi M, Cai L, Li X, Li Y, Tan Y. Activating AMP-activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection from Nonalcoholic Fatty Liver Disease in Mice. Hepatology. 2020 Sep 23. doi: 10.1002/hep.31568. Epub ahead of print. PMID: 32965675.
  13. Mohamed TMA, Conklin DJ. Emerging technology and platforms for cardiotoxicity testing. Toxicol Appl Pharmacol. 2020 Dec 1;408:115262. doi: 10.1016/j.taap.2020.115262. Epub 2020 Oct 2. PMID: 33017593.
  14. Lynch J, Jin L, Richardson A, Conklin DJ. Tobacco Smoke and Endothelial Dysfunction: Role of Aldehydes? Curr Hypertens Rep. 2020 Aug 28;22(9):73. doi: 10.1007/s11906-020-01085-7. PMID: 32857217.
  15. Miller JM, Meki MH, Ou Q, George SA, Gams A, Abouleisa RRE, Tang XL, Ahern BM, Giridharan GA, El-Baz A, Hill BG, Satin J, Conklin DJ, Moslehi J, Bolli R, Ribeiro AJS, Efimov IR, Mohamed TMA. Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity. Toxicol Appl Pharmacol. 2020 Nov 1;406:115213. doi: 10.1016/j.taap.2020.115213. Epub 2020 Aug 30. PMID: 32877659; PMCID: PMC7554180.
  16. Tyagi A, Chandrasekaran B, Kolluru V, Baby BV, Sripathi CA, Ankem MK, Ramisetti SR, Chirasani VR, Dokholyan NV, Sharma AK, Damodaran C. ASR490, a Small Molecule, Overrides Aberrant Expression of Notch1 in colorectal cancer. Mol Cancer Ther. 2020 Oct 21:molcanther.0949.2019. doi: 10.1158/1535-7163.MCT-19-0949. Epub ahead of print. PMID: 33087513.
  17. Hawkins AT, Wise PE, Chan T, Lee JT, Glyn T, Wood V, Eglinton T, Frizelle F, Khan A, Hall J, Ilyas MIM, Michailidou M, Nfonsam VN, Cowan ML, Williams J, Steele SR, Alavi K, Ellis CT, Collins D, Winter DC, Zaghiyan K, Gallo G, Carvello M, Spinelli A, Lightner AL. Diverticulitis: An Update From the Age Old Paradigm. Curr Probl Surg. 2020 Oct;57(10):100862. doi: 10.1016/j.cpsurg.2020.100862. Epub 2020 Jul 18. PMID: 33077029; PMCID: PMC7575828.
  18. Shrader SH, Tong YG, Duff MB, Freedman JH, Song ZH. Involvement of dopamine receptor in the actions of non-psychoactive phytocannabinoids. Biochem Biophys Res Commun. 2020 Oct 21:S0006-291X(20)31930-6. doi: 10.1016/j.bbrc.2020.10.021. Epub ahead of print. PMID: 33097185.
  19. Hein DW, Millner LM. Arylamine N-acetyltransferase acetylation polymorphisms: paradigm for pharmacogenomic-guided therapy- a focused review. Expert Opin Drug Metab Toxicol. 2020 Nov 3:1-13. doi: 10.1080/17425255.2021.1840551. Epub ahead of print. PMID: 33094670. PMCID 7790970.
  20. Hong KU, Doll MA, Lykoudi A, Salazar-González RA, Habil MR, Walls KM, Bakr AF, Ghare SS, Barve SS, Arteel GE, Hein DW. Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2. Toxicol Rep. 2020 Sep 28;7:1319-1330. doi: 10.1016/j.toxrep.2020.09.011. PMID: 33083237; PMCID: PMC7553889.
  21. Nardi D, Waite R, Nowak M, Hatcher B, Hines-Martin V, Stacciarini JR. Achieving Health Equity Through Eradicating Structural Racism in the United States: A Call to Action for Nursing Leadership. J Nurs Scholarsh. 2020 Oct 1. doi: 10.1111/jnu.12602. Epub ahead of print. PMID: 33002309.
  22. Metcalf S, Petri BJ, Kruer T, Green B, Dougherty S, Wittliff JL, Klinge CM, Clem BF. Serine synthesis influences tamoxifen response in ER+ human breast carcinoma. Endocr Relat Cancer. 2020 Oct 1:ERC-19-0510.R2. doi: 10.1530/ERC-19-0510. Epub ahead of print. PMID: 33112838.
  23. Shi H, Jin J, Hardesty JE, Falkner KC, Prough RA, Balamurugan AN, Mokshagundam SP, Chari ST, Cave MC. Corrigendum to "Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes" [Toxicology & Applied Pharmacology, 363 (2018) 22-33]. Toxicol Appl Pharmacol. 2020 Oct 1;404:115149. doi: 10.1016/j.taap.2020.115149. Epub 2020 Jul 20. Erratum for: Toxicol Appl Pharmacol. 2019 Jan 15;363:22-33. PMID: 32702359.
  24. Leggett CS, Doll MA, States JC, Hein DW. Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes. Arch Toxicol. 2020 Nov 2. doi: 10.1007/s00204-020-02901-4. Epub ahead of print. PMID: 33136180.
  25. Ferragut Cardoso AP, Udoh KT, States JC. Arsenic-induced changes in miRNA expression in cancer and other diseases. Toxicol Appl Pharmacol. 2020 Oct 28;409:115306. doi: 10.1016/j.taap.2020.115306. Epub ahead of print. PMID: 33127375.
  26. Mandal RK, Denny JE, Waide ML, Li Q, Bhutiani N, Anderson CD, Baby BV, Jala VR, Egilmez NK, Schmidt NW. Temporospatial shifts within commercial laboratory mouse gut microbiota impact experimental reproducibility. BMC Biol. 2020 Jul 3;18(1):83. doi: 10.1186/s12915-020-00810-7. PMID: 32620114; PMCID: PMC7334859.
  27. Annett RD, Chervinskiy S, Chun TH, Cowan K, Foster K, Goodrich N, Hirschfeld M, Hsia DS, Jarvis JD, Kulbeth K, Madden C, Nesmith C, Raissy H, Ross J, Saul JP, Shiramizu B, Smith P, Sullivan JE, Tucker L, Atz AM. IDeA States Pediatric Clinical Trials Network for Underserved and Rural Communities. Pediatrics. 2020 Oct;146(4):e20200290. doi: 10.1542/peds.2020-0290. Epub 2020 Sep 17. PMID: 32943534.
  28. Kolonics F, Kajdácsi E, Farkas VJ, Veres DS, Khamari D, Kittel Á, Merchant ML, McLeish KR, Lőrincz ÁM, Ligeti E. Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions. J Leukoc Biol. 2020 Sep 18. doi: 10.1002/JLB.3A0320-210R. Epub ahead of print. PMID: 32946637.
  29. Samuel G, Crow J, Klein JB, Merchant ML, Nissen E, Koestler DC, Laurence K, Liang X, Neville K, Staggs V, Ahmed A, Atay S, Godwin AK. Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers. Oncotarget. 2020 Aug 4;11(31):2995-3012. doi: 10.18632/oncotarget.27678. PMID: 32821345; PMCID: PMC7415402.
  30.  Satoskar AA, Shapiro JP, Jones M, Bott C, Parikh SV, Brodsky SV, Yu L, Nagaraja HN, Wilkey DW, Merchant ML, Klein JB, Nadasdy T, Rovin BH. Differentiating Staphylococcus infection-associated glomerulonephritis and primary IgA nephropathy: a mass spectrometry-based exploratory study. Sci Rep. 2020 Oct 14;10(1):17179. doi: 10.1038/s41598-020-73847-x. PMID: 33057112; PMCID: PMC7560901.
  31. Sears L, Sears CG, Myers JV, Brock GN, Zierold KM. Associations of the Behavioral Assessment and Research System (BARS) neurobehavioral outcomes with attention problems in children living near coal ash storage sites. Neurotoxicology. 2020 Aug 15;81:11-17. doi: 10.1016/j.neuro.2020.08.002. Epub ahead of print. PMID: 32810513.
  32. Kim C, States JC, Ceresa BP. Chronic and acute arsenic exposure enhance EGFR expression via distinct molecular mechanisms. Toxicol In Vitro. 2020 Sep;67:104925. doi: 10.1016/j.tiv.2020.104925. Epub 2020 Jun 26. PMID: 32599262; PMCID: PMC7375208.
  33. Bushau-Sprinkle A, Barati MT, Gagnon KB, Khundmiri SJ, Kitterman K, Hill BG, Sherwood A, Merchant M, Rai SN, Srivastava S, Clark B, Siskind L, Brier M, Hata J, Lederer E. NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex. Antioxidants (Basel). 2020 Sep 14;9(9):862. doi: 10.3390/antiox9090862. PMID: 32937931; PMCID: PMC7554817.
  34. Mo Y, Zhang Y, Mo L, Wan R, Jiang M, Zhang Q. The role of miR-21 in nickel nanoparticle-induced MMP-2 and MMP-9 production in mouse primary monocytes: In vitro and in vivo studies. Environ Pollut. 2020 Dec;267:115597. doi: 10.1016/j.envpol.2020.115597. Epub 2020 Sep 4. PMID: 33254626; PMCID: PMC7708676.