Current Studies

Current Studies

Now Enrolling!

Childhood Obesity in African American Males 10 to less than 14 year olds

IRB #13.0334

The UofL Kosair Charities Pediatric Clinical Research Unit at Kosair Children’s Hospital is conducting a research study to evaluate the effect of an investigational product on childhood obesity. African American Males from 10 to less than 14 years of age who are overweight or obese may be eligible for participation. If a child qualifies to take part in this research study, he will receive the product or placebo and study related care at no cost. Compensation will be provided for time/travel.

For additional information, call Molly Harper by email or at 629-4695 or 620-0000 (pager)

PKU Study for 18 to 70 years old

IRB #13.0311

The Kosair Charities Pediatric Clinical Research Unit is conducting a clinical research study to evaluate the safety and tolerability of a medication in 18 to 70 year olds who have a diagnosis of PKU with a high Phe level. If the patient qualifies to take part in this research study, involvement lasts from 27 to 44 weeks with up to 15 study visits. They will receive the study medication and study-related care at no cost. Compensation available for time/travel.

For additional information, contact Lauren Rayborn, RN by email or at 629-7544 or 620-0000 (pager)

Type 1 Diabetes Mellitus Study for Adolescents and Adults aged 12 to 35 years

IRB #12.0380

The Kosair Charities Pediatric Clinical Research Unit and the Wendy L. Novak Diabetes Care Center are conducting a clinical research study to evaluate the safety of an experimental medication in 12 to 35 years olds who have recently been diagnosed with Type 1 Diabetes. If the subject qualifies to take part in this research study, participation lasts up to 2 years; he/she will receive the study medication or a placebo and study-related care at no cost . Compensation available for time/travel.

For additional information, contact Kupper Wintergerst, MD or Lauren Rayborn, RN by email or at 629-7544 or 620-0000 (pager)

Type 2 diabetes mellitus study for children and adolescents aged 10 to 17 years

IRB #12.0380

The Kosair Charities Pediatric Clinical Research Unit and the Wendy L. Novak Diabetes Care Center are conducting a clinical research study to evaluate the metabolism, as well as safety, of a medication in children and adolescents aged 10 to 17 years old who have been diagnosed with Type 2 Diabetes. If the child qualifies to take part in this research study, he/she will attend 3 clinic visits; receive the study medication and study-related care at no cost. Compensation available for time/travel.

For additional information, contact Kupper Wintergerst or Lauren Rayborn by email or at 629-7544 or 620-0000 (pager).

Autism study for children 4 to 10 years old

IRB #13.0779

The UofL Kosair Charities Pediatric Clinical Research Unit at Kosair Children's Hospital is conducting a clinical research study to evaluate how a medication treats abnormal EEG’s without seizures, as well as behavioral and neurological symptoms, in children with Autism Spectrum Disorder (ASD). If a child qualifies to take part in this research study, he/she will receive the study medication or placebo and study-related care at no cost. Parents will be offered compensation for time/travel.

For additional information, contact Bethany Stock, 629-4696 or 620-0000 (pager).

Research Study for Nausea and Vomiting after a Scheduled Surgery, Birth through less than 2 years

IRB # 12.0552

The UofL Kosair Charities Pediatric Clinical Research Unit at Kosair Children’s Hospital is conducting a clinical research study to evaluate the safety and dose response of a drug given by mouth prior to a scheduled surgery that is used to prevent post-operative nausea and vomiting. Children from birth to less than 2 years of age may be eligible for participation. Subjects may be compensated for time/travel.

If your child is scheduled or being scheduled for surgery, please call 629-5820 or 620-0000 (pager) to speak to study personnel or email c0kono01@louisville.edu

Pain Study, Infants, birth to less than 28 days

IRB #12.0228

The UofL Kosair Charities Pediatric Clinical Research Unit at Kosair Children’s Hospital is conducting a clinical research study to evaluate acetaminophen given into a vein to treat moderate to severe pain in infants less than 28 days of age following surgery or an injury. Subjects may be compensated for time/travel.

For more information, contact Jackie Perry at 629-5820 or 620-0000 (pager).

Pediatric pain study, 7 through 16 years

IRB #12.0192

The UofL Kosair Charities Pediatric Clinical Research Unit at Kosair Children's Hospital is conducting a clinical research study to evaluate the safety, pharmacokinetics and efficacy of an investigational drug used to treat moderate to severe prolonged or persistent pain.  Children 7 to less than 17 years of age who require continuous analgesia for moderate to severe pain for an extended period of time may be eligible for participation.  Patients will be reimbursed for reasonable travel costs associated with their participation in the study.

For more information, contact Karrie Kernen, 629-5820 or 620-0000 (pager).

Pediatric constipation study

IRB# 14.0007

The UofL Kosair Charities Pediatric Clinical Research Unit is conducting a clinical research study to assess the efficacy and safety of an investigational drug used to treat constipation. Children 6-17 years of age who have been diagnosed with functional constipation and are able to swallow capsules may be eligible to participate. Patients may be compensated for time/travel associated with their participation in the study.

For more information, contact Jackie Perry, 629-5123, pager 620-0000.