There are several exemptions to the new KASPER requirements.

General Exceptions for all Prescriptions

• A patient admitted to inpatient, outpatient or observation status of a hospital
• A patient as part of hospice or end of life treatment
• To a patient for the treatment of pain associated with cancer or the treatment of cancer
• During times of disaster or mass casualty directly impacting the physician’s practice
• In a single dose prescribed/dispensed to relieve anxiety/pain/discomfort by a patient subjecting to a diagnostic test or procedure
• Schedule V controlled substances

Special Additional Exceptions/Limitations for Schedule II controlled substances and scheduled III controlled substances

• Prescribing or administering a controlled substance to treat an emergency situation
• Prescribing or dispensing for administration to a patient admitted to a hospital or long-term care facility if the facility or practitioner places a KASPER report on the chart within 12 hours of admission
• Prescribing or dispensing no more than a 14-day supply to a patient following an operative or invasive procedure or delivery
• Prescribing or dispensing a substitute prescription within 7 days of the initial prescription so long as any refills to the initial prescription are cancelled and the patient is required to dispose of any unused medication
• Prescribing or dispensing to the same patient for the same condition by a partner in practice with the initial prescriber (or other coverage arrangement) within 90 days of 
the initial prescription
• Prescribing or dispensing to research subject enrolled in an IRB-approved single, double or triple blind study, or is otherwise covered by an NIH certificate of confidentiality