Featured Publications

  • Blancquaert L, Baba SP, Kwiatkowski S, Stautemas J, Stegen S, Barbaresi S, Chung W, Boakye AA, Hoetker JD, Bhatnagar A, Delanghe J, Vanheel B, Veiga-da-Cunha M, Derave W, Everaert I. Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by beta-alanine transamination. J Physiol. 2016 Apr . PMID27062388.
  • Conklin DJ, Guo Y, Jagatheesan G, Kilfoil PJ, Haberzettl P, Hill BG, Baba SP, Guo L, Wetzelberger K, Obal D, Rokosh DG, Prough RA, Prabhu SD, Velayutham M, Zweier JL, Hoetker JD, Riggs DW, Srivastava S, Bolli R, Bhatnagar A. Genetic deficiency of GlutathioneS-transferase P increases myocardial sensitivity to ischemia-reperfusion injury.Circ Res. 2015 Aug 14; 117(5);439-49. PMID 26169370.
  • Brainard RE, Watson LJ, Demartino AM, Brittian KR, Readnower RD, Boakye AA, Zhang D, Hoetker JD, Bhatnagar A, Baba SP, Jones SP. Hight fat feeding in mice is insufficient to induce cardiac dysfunction and doesnot exacerbate heart failure.PLoS One. 2013 Dec;8(12): PMID:24367585.
  • Baba SP, Hoetker DJ, Cai J, Barski AO, Conklin JD, Bhatnagar A. Role of aldose reductase in the metabolism and detoxification of carnosine aldehyde conjugates.  J. Biol. Chem. 2013 Sep 27; 288 (39):28163-79: PMID:23313711.
  • Baba SP, Hellmann J, Srivastava S, Bhatnagar A. Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE) Chem Biol Interact. 2011 May 30;191(1-3):357-63;PMID:21276777.
  • Wheat LA, Haberzettl P, Hellmann J, Baba SP, Bertke M, Lee J, McCracken J, O'Toole TE, Bhatnagar A, Conklin DJ. Acrolein inhalation prevents vascular endothelial growth factor induced mobilization of Flk-1+/Sca-1+ cells in mice. Arterioscler Thromb Vasc Biol. 2011;PMID:21527748.
  • Wetzelberger K, Baba SP, Thirunavukkarasu M, Ho YS, Maulik N, Barski OA, Conklin DJ, Bhatnagar A. Postischemic deactivation of cardiac aldose reductase:role of glutathione S-transferase P and glutaredoxin in regeneration of reduced thiols from sulfenic acids J Biol Chem. 2010 Aug 20;285(34):26135-48. PMID:20538586.
  • Baba SP, Barski OA, Ahmed Y, O'Toole TE, Conklin DJ, Bhatnagar A, Srivastava S. Reductive metabolism of AGE precursors: A metabolism route for preventing AGE accumulation in cardiovascular tissue. Diabetes. :58 (11); 2486-97 2009: PMID:19061876.
  • Baba SP, Wetzelberger K, Hoetker JD, Bhatnagar A. Posttranslational glutathiolation of aldose reductase (AKR1B1): a possible mechanism of protein recovery from S-nitrosylation. Chem Biol Interact.  16;178 (1-3):250-8.  2008. PMID:1965181.