Oct. 29: R!L Keynote Address (virtual) and Awards Ceremony (virtual)

R!L keynote address is virtual (See MS Teams link in description below.)
When Oct 29, 2021
from 01:00 PM to 02:45 PM
Contact Name
Contact Phone 852-2647 or 502-550-3928
Attendees administrators, research faculty, staff, students, fellows, post-docs, community
Add event to calendar vCal
iCal

R!L Keynote Speaker

Research!Louisville 2021 Keynote Speaker

Mary Jo Turk, Ph.D., Professor of Microbiology and Immunology, Geisel School of Medicine, Dartmouth College

Co-director, Immunology and Cancer Immunotherapy Program, Norris-Cotton Cancer Center

Lecture title: Lymph node resident memory T responses to metastatic melanoma

Highlights:

While immune responses against primary tumors are critically important, T cells must also be capable of functioning at sites where cancers metastasize. Our laboratory investigated how resident memory (Trm) and circulating memory (Tcirm) CD8 T cells potentiate immunity to cancer in diverse tissue microenvironments. Based on a mouse model of immunity to melanoma with associated autoimmune vitiligo, we found that tumor-specific memory T cells form a widespread network of transcriptionally distinct subsets throughout lymphoid tissues and visceral organs. Among these, we discovered a population of Trm cells that reside durably within lymph nodes (LN), where they protect against invading melanoma cells. These LN-Trm cells adopt a transcriptional program that is distinct from Trm cells in other tissues, and which uniquely predicts survival in melanoma patients with regional LN metastases. This work reveals a novel role for Trm cells in durable immunity to cancer at crucial sites of metastasis.

Microsoft Teams meeting

Join on your computer or mobile app

Click here to join the meeting

Or call in (audio only)

+1 502-792-9582,,120961257#   United States, Louisville

Phone Conference ID: 120 961 257#

Find a local number | Reset PIN

Awards Ceremony will be virtual: Winners of R!L 2021 scientific poster competitions will be announced via a slide presentation. Certificates will be available the following week.