Program
Events planned for the Tamburro Symposium on Environmental Chemicals and Liver Disease
- Conference Organizer
- Matt Cave, MD, University of Louisville
- Welcome and Introduction to Environmental Liver Disease
- Matt Cave, MD, University of Louisville
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- Session 1
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Mechanisms of Liver injury and Fibrosis
- Moderation
- Craig McClain, MD, University of Louisville
- Bob Roth, PhD, DABT, Michigan State University
- Role of Nutrition and the Gut:Liver Axis in HepatotoxicityCraig McClain, MD, University of Louisville
- Pediatric Steatohepatitis Mechanisms and Environmental ExposuresMiriam Vos, MD, MSPH, Emory University
- Mechanisms of Drug Induced Liver Injury (DILI) and the DILI Network ExperienceRaj Vuppalanchi, MD, Indiana University
- Role of Inflammation in HepatotoxicityBob Roth, PhD, DABT, Michigan State University
- Liver Fibrosis and Extracellular Matrix HomeostasisGavin Arteel, PhD, University of Louisville
- Break and Poster Session
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- Session 2
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Hepatic Xenobiotic Metabolism
- Moderation
- Russ Prough, PhD, University of Louisville
- Jose Manautou, PhD, University of Connecticut
- Phase 1 and Phase 2 Xenobiotic MetabolismRuss Prough, PhD, University of LouisvilleDavid Hein, PhD, University of Louisville
- Hepatic Xenobiotic TransportersAngela Slitt, PhD, University of Rhode Island
- Utilization of System Genomics in the Identification of Genetic Determinants of Adaptation to Chemical Liver InjuryJose Manautou, PhD, University of Connecticut
- Genes and Big Jeans: Synergistic Interaction of Pharmacogenetics and Disease in Adverse Drug ReactionsNathan Cherrington, PhD, University of Arizona
- Lunch Break and Poster Judging Session
- Moderation
- Swati Joshi-Barve, PhD, University of Louisville
- Break-out Lecture
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Ethical, Legal, and Social Issues Surrounding Environmental Health ResearchLauren Heberle, PhD, University of Louisville
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- Session 3
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Halogenated Aliphatics and Metal(oids)
- Moderation
- Jim Luyendyk, PhD, Michigan State University
- Vinyl Chloride and SteatohepatitisJulianne Beier, PhD, University of Louisville
- TRPV4: A Novel Master Regulator of Disease Progression in Bromodichloromethane-Induced Nonalcoholic SteatohepatitisSaurahb Chatterjee, PhD, University of South Carolina
- Role of Arsenic in Non-Alcoholic Fatty Liver DiseaseBert Watson, PhD, University of Louisville
- Arsenic and the Impact of Mechanisms Coupling Coagulation to Fatty Liver DiseaseJim Luyendyk, PhD, Michigan State University
- Cadmium and SteatohepatitisDean Jones, PhD, Emory University
- Invitation Only
- Dinner Reception and Seminar
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Hepatotoxicity in NTP StudiesDavid Malarkey, DVM, PhD, DACVP, NIEHS
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- Session 4
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Polycyclic Aromatic Hydrocarbons
- Moderation
- Matt Cave, MD, University of Louisville
- Dioxins and SteatohepatitisTim Zacharewski, PhD, Michigan State University
- Reprogramming of the Hepatocyte Genome by Benzo[α]pyreneKen Ramos, MD, PhD, PharmB, University of Arizona
- Polychlorinated Biphenyls in SteatohepatitisMatt Cave, MD, University of Louisville
- The Hepatic Function of AhR: The Expected and UnexpectedWen Xie, PhD, University of Pittsburgh
- Break and Poster Session
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- Session 5
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Chemical Hepatocarcinogenesis
- Moderation
- Ken Ramos, MD, PhD, PharmB, University of Arizona
- David Hein, PhD, University of Louisville
- Xenobiotics and Liver CancerGarry Williams, MD, New York Medical CollegeTetyana Kobets, MD, MSPH, New York Medical College, FDA: NCTR
- Dietary Modulation of Aflatoxin Carcinogenesis: Functional Importance of Species Differences in BiotransformationDave Eaton, PhD, University of Washington
- Vinyl Chloride Related Hemangiosarcoma–The Louisville ExperienceMatt Cave, MD, University of Louisville
- The William Waddell Memorial Seminar–Vinyl Chloride, Liver Cancer, and DNA AdductsJim Swenberg, DVM, PhD, University of North Carolina
- Lunch and Presentation of Poster Session Awards
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- Session 6
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Alternative Testing Strategies, Systems Biology, and Biomarkers for Liver Disease
- Moderation
- Jim Klaunig, PhD, Indiana University
- v-Liver™ and ToxCast™Imran Shah, PhD, EPA
- Imaging Biomarkers for Liver DiseaseSudhakar Venkatesh, MD, Mayo Clinic
- Session 7
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Panel Discussion–Integration, Identification of Knowledge Gaps, Future Directions for Research
- Moderation
- Matt Cave, MD, University of Louisville
- End